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The impact of adjuvant EGFR-TKIs and 14-gene molecular assay on stage I non-small cell lung cancer with sensitive EGFR mutations. EClinicalMedicine. 2023 Oct; 64:102205.
Jiang Y, Lin Y, Fu W, He Q, Liang H, Zhong R, Cheng R, Li B, Wen Y, Wang H, Li J, Li C, Xiong S, Chen S, Xiang J, Mann MJ, He J, Liang W. PMID: 37745018; PMCID: PMC10511786.
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7
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Caffeine consumption and onset of alcohol use among early adolescents. Prev Med. 2022 10; 163:107208.
Kristjansson AL, Mann MJ, Smith ML, Kogan SM, Lilly CL, James JE. PMID: 35987370; PMCID: PMC10163886.
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2 Fields:
Translation:
Humans
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Genetic and immunologic features of recurrent stage I lung adenocarcinoma. Sci Rep. 2021 12 08; 11(1):23690.
Kratz JR, Li JZ, Tsui J, Lee JC, Ding VW, Rao AA, Mann MJ, Chan V, Combes AJ, Krummel MF, Jablons DM. PMID: 34880292; PMCID: PMC8654957.
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4 Fields:
Translation:
Humans
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Improved outcomes and staging in non-small-cell lung cancer guided by a molecular assay. Future Oncol. 2021 Dec; 17(34):4785-4795.
Gupta AR, Woodard GA, Jablons DM, Mann MJ, Kratz JR. PMID: 34435876; PMCID: PMC9039775.
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2 Fields:
Translation:
Humans
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Molecular Risk Stratification is Independent of EGFR Mutation Status in Identifying Early-Stage Non-Squamous Non-Small Cell Lung Cancer Patients at Risk for Recurrence and Likely to Benefit From Adjuvant Chemotherapy. Clin Lung Cancer. 2021 11; 22(6):587-595.
Woodard GA, Kratz JR, Haro G, Gubens MA, Blakely CM, Jones KD, Mann MJ, Jablons DM. PMID: 34544620.
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6 Fields:
Translation:
Humans
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Resectability, Recurrence, and Risk Stratification of Giant Solitary Fibrous Tumors in the Thoracic Cavity. Ann Surg Oncol. 2021 Sep; 28(9):4953-4959.
Woodard GA, Fels Elliott DR, Yap A, Haro GJ, Kratz JR, Mann MJ, Jones KD, Jablons DM. PMID: 33728541.
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4 Fields:
Translation:
Humans
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MO01.13 Molecular Risk Stratification is Independent of EGFR Mutation Status in Identifying Early Stage Non-Squamous Non-Small Cell Lung Cancer Patients at Risk for Recurrence and Likely to Benefit from Adjuvant Chemotherapy. Journal of Thoracic Oncology. 2021 Jan 1; 16(1):s21.
Woodard WG, Kratz KJ, Haro HG, Gubens GM, Blakely BC, Jones JK, Mann MM, Jablons JD. .
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Comparison of Conventional TNM and Novel TNMB Staging Systems for Non-Small Cell Lung Cancer. JAMA Netw Open. 2019 12 02; 2(12):e1917062.
Haro GJ, Sheu B, Cook NR, Woodard GA, Mann MJ, Kratz JR. PMID: 31808928; PMCID: PMC6902768.
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10 Fields:
Translation:
Humans
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MA06.09 Timing of Driver Mutation Development and the Genetic Evolution of Semi-Solid Lung Nodules into Early NSCLC. Journal of Thoracic Oncology. 2019 Oct 1; 14(10):s271-s272.
Woodard WG, Ding DV, Kim KI, Jones JK, Chavez CG, Haro HG, Kratz KJ, Mann MM, Rotow RJ, Blakely BC, Jablons JD. .
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Differential gene expression identifies KRT7 and MUC1 as potential metastasis-specific targets in sarcoma. Cancer Manag Res. 2019; 11:8209-8218.
Jiang L, Tolani B, Yeh CC, Fan Y, Reza JA, Horvai AE, Xia E, Kratz JR, Jablons DM, Mann MJ. PMID: 31686913; PMCID: PMC6751227.
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5
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Incorporation of a Molecular Prognostic Classifier Improves Conventional Non-Small Cell Lung Cancer Staging. J Thorac Oncol. 2019 07; 14(7):1223-1232.
Kratz JR, Haro GJ, Cook NR, He J, Van Den Eeden SK, Woodard GA, Gubens MA, Jahan TM, Jones KD, Kim IJ, He B, Jablons DM, Mann MJ. PMID: 30959120.
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12 Fields:
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Humans
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P2.16-12 Expanded Data Confirm Molecular Testing Identifies Lung Adenocarcinoma Patients, Including Stage IA, Who Benefit from Adjuvant Chemotherapy. Journal of Thoracic Oncology. 2018 Oct 1; 13(10):s835.
Woodard WG, Wang WS, Kratz KJ, Haro HG, Gubens GM, Blakely BC, Jahan JT, Jones JK, Mann MM, Jablons JD. .
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P3.03-24 Incorporation of a Molecular Prognostic Classifier Improves Conventional Non-Small Cell Lung Cancer Staging. Journal of Thoracic Oncology. 2018 Oct 1; 13(10):s919.
Haro HG, Kratz KJ, Cook CN, He HJ, Van Den Eeden VS, Woodard WG, Gubens GM, Jahan JT, Jones JK, Kim KI, He HB, Jablons JD, Mann MM. .
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Propensity Matched Analysis of Perioperative Outcomes in Robotic-Assisted Thoracic Surgery, Video Assisted Thoracic Surgery, and Open Lung Resections. Journal of the American College of Surgeons. 2018 Oct 1; 227(4):s53.
Haro HG, Kratz KJ, Jablons JD, Mann MM, Kukreja KJ. .
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A review of soft-tissue sarcomas: translation of biological advances into treatment measures. Cancer Manag Res. 2018; 10:1089-1114.
Hoang NT, Acevedo LA, Mann MJ, Tolani B. PMID: 29785138; PMCID: PMC5955018.
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52
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Shift toward greater pathologic post-myocardial infarction remodeling with loss of the adaptive hypertrophic signaling of alpha1 adrenergic receptors in mice. PLoS One. 2017; 12(12):e0188471.
Yeh CC, Fan Y, Xu Y, Yang YL, Simpson PC, Mann MJ. PMID: 29216197; PMCID: PMC5720786.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Atrial ERK1/2 activation in the embryo leads to incomplete Septal closure: a novel mouse model of atrial Septal defect. J Biomed Sci. 2017 Nov 24; 24(1):89.
Yeh CC, Fan Y, Yang YL, Mann MJ. PMID: 29178881; PMCID: PMC5702213.
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2 Fields:
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HumansAnimalsCells
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Adjuvant Chemotherapy Guided by Molecular Profiling and Improved Outcomes in Early Stage, Non-Small-Cell Lung Cancer. Clin Lung Cancer. 2018 01; 19(1):58-64.
Woodard GA, Wang SX, Kratz JR, Zoon-Besselink CT, Chiang CY, Gubens MA, Jahan TM, Blakely CM, Jones KD, Mann MJ, Jablons DM. PMID: 28645632.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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OA19.06 Adjuvant Chemotherapy Decisions Based on Molecular Risk Status Improves Outcomes in Early Stage, Non-Small Cell Lung Cancer. Journal of Thoracic Oncology. 2017 Jan 1; 12(1):s320.
Woodard WG, Crockard CJ, Zoon-Besselink ZC, Kratz KJ, Gubens GM, Jahan JT, Blakely BC, Jones JK, Mann MM, Jablons JD. .
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P1.03-066 Incorporation of a Molecular Prognostic Classifier Improves Conventional Non-Small Cell Lung Cancer TNM Staging Topic: Staging. Journal of Thoracic Oncology. 2017 Jan 1; 12(1):s584-s585.
Kratz KJ, Cook CN, Woodard WG, Jones JK, Gubens GM, Jahan JT, Kim KI, He HB, Jablons JD, Mann MM. .
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Spacial and Temporal Patterns of Gene Expression After Cardiac MEK1 Gene Transfer Improve Post-Infarction Remodeling Without Inducing Global Hypertrophy. J Cell Biochem. 2017 04; 118(4):775-784.
Fan Y, Yang YL, Yeh CC, Mann MJ. PMID: 27639174.
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2 Fields:
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HumansAnimalsCells
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Genistein Suppresses Growth of Human Uterine Sarcoma Cell Lines via Multiple Mechanisms. Anticancer Res. 2015 Jun; 35(6):3167-73.
Yeh CC, Fan Y, Jiang L, Yang YL, He B, You L, Mann M. PMID: 26026076.
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6 Fields:
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HumansAnimalsCells
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Prognostic molecular assay might improve identification of patients at risk for recurrence in early-stage non-small-cell lung cancer. Clin Lung Cancer. 2014 Nov; 15(6):426-32.
Woodard GA, Gubens MA, Jahan TM, Jones KD, Kukreja J, Theodore PR, Cardozo S, Jew G, Clary-Macy C, Jablons DM, Mann MJ. PMID: 25258195.
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4 Fields:
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Humans
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Aggressive and minimally invasive surgery for pulmonary metastasis of sarcoma. J Thorac Cardiovasc Surg. 2014 Apr; 147(4):1193-200; discussion 1200-1.
Reza J, Sammann A, Jin C, Horvai A, Hudnall M, Jablons DM, Jahan T, Kornak J, Mann MJ. PMID: 24507991.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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VATS lobectomy facilitates the delivery of adjuvant docetaxel-carboplatin chemotherapy in patients with non-small cell lung cancer. J Thorac Dis. 2013 Oct; 5(5):578-84.
Zhi X, Gao W, Han B, Yang Y, Li H, Liu D, Wang C, Min G, Long H, Rigas JR, Carey M, Jahan T, Sammann A, Reza J, Wang D, Mann MJ, Jablons DM, He J, China Clinical Trials Consortium. PMID: 24255769; PMCID: PMC3815738.
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4
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Novel video-assisted thoracoscopic surgery metastatectomy technique equivalent to open thoracotomy for identification of numerous and small lesions. Journal of the American College of Surgeons. 2013 Sep 1; 217(3):s43.
Reza RJ, Hudnall HM, Sammann SA, Jablons JD, Mann MM. .
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International trial of adjuvant therapy in high risk stage I non-squamous cell carcinoma identified by a 14-gene prognostic signature. Transl Lung Cancer Res. 2013 Jun; 2(3):222-5.
Kratz JR, Mann MJ, Jablons DM. PMID: 25806235; PMCID: PMC4367604.
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6
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Analytical validation of a practical molecular assay prognostic of survival in nonsquamous non-small cell lung cancer. Diagn Mol Pathol. 2013 Jun; 22(2):65-9.
Kratz JR, Tham PT, Mulvihill MS, Ziaei F, Ray MR, Hurst JW, Segal MR, Berryman DM, Chu W, He B, Jablons DM, Mann MJ. PMID: 23628816.
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11 Fields:
Translation:
Humans
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Impact of a multigene prognostic assay on postoperative management of early-stage non-small cell lung cancer. Journal of Clinical Oncology. 2013 May 20; 31(15_suppl):e22124-e22124.
Dormady DS, Jahan JT, Mann MM, Jablons JD, Broder BM, DeCristofaro DA, Anene AA. .
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Prognostic assay in small, node-negative non-small cell lung cancer--reply. JAMA. 2013 Feb 27; 309(8):769-70.
Mann MJ, Jablons DM, Kratz JR. PMID: 23443437.
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MEK1-induced physiological hypertrophy inhibits chronic post-myocardial infarction remodeling in mice. J Cell Biochem. 2013 Jan; 114(1):47-55.
Yeh CC, Malhotra D, Yang YL, Xu Y, Fan Y, Li H, Mann MJ. PMID: 22821618.
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5 Fields:
Translation:
AnimalsCells
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A prognostic assay to identify patients at high risk of mortality despite small, node-negative lung tumors. JAMA. 2012 Oct 24; 308(16):1629-31.
Kratz JR, Van den Eeden SK, He J, Jablons DM, Mann MJ. PMID: 23093159.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Pulmonary metastasectomy: Improving survival with less invasive, more aggressive surgery. Journal of the American College of Surgeons. 2012 Sep 1; 215(3):s46.
Reza RJ, Sammann SA, Grimes GB, Mann MM. .
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A practical molecular assay to predict survival in resected non-squamous, non-small-cell lung cancer: development and international validation studies. Lancet. 2012 Mar 03; 379(9818):823-32.
Kratz JR, He J, Van Den Eeden SK, Zhu ZH, Gao W, Pham PT, Mulvihill MS, Ziaei F, Zhang H, Su B, Zhi X, Quesenberry CP, Habel LA, Deng Q, Wang Z, Zhou J, Li H, Huang MC, Yeh CC, Segal MR, Ray MR, Jones KD, Raz DJ, Xu Z, Jahan TM, Berryman D, He B, Mann MJ, Jablons DM. PMID: 22285053; PMCID: PMC3294002.
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PubMed Mentions:
168 Fields:
Translation:
Humans
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IL11 is prognostic of survival in lung adenocarcinoma. Journal of the American College of Surgeons. 2011 Sep 1; 213(3):s38-s39.
Kratz KJ, Pham PP, Mulvihill MM, Ray RM, Mann MM, Jablons JD. .
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Stem Cell Transplantation to the Heart. . 2010 Oct 7; 279-297.
Mann MM. .
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Biomimetic matrices for myocardial stabilization and stem cell transplantation. J Biomed Mater Res A. 2010 Dec 15; 95(4):1055-66.
Wall ST, Yeh CC, Tu RY, Mann MJ, Healy KE. PMID: 20878934; PMCID: PMC2975774.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Distinctive ERK and p38 signaling in remote and infarcted myocardium during post-MI remodeling in the mouse. J Cell Biochem. 2010 Apr 15; 109(6):1185-91.
Yeh CC, Li H, Malhotra D, Turcato S, Nicholas S, Tu R, Zhu BQ, Cha J, Swigart PM, Myagmar BE, Baker AJ, Simpson PC, Mann MJ. PMID: 20186881; PMCID: PMC3397305.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Heart Failure Switches RV Inotropic Responses from Negative to Positive. Biophysical Journal. 2010 Jan 1; 98(3):715a.
Wang WG, Yeh YC, Jensen JB, Mann MM, Simpson SP, Baker BA. .
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Heart failure switches the RV alpha1-adrenergic inotropic response from negative to positive. Am J Physiol Heart Circ Physiol. 2010 Mar; 298(3):H913-20.
Wang GY, Yeh CC, Jensen BC, Mann MJ, Simpson PC, Baker AJ. PMID: 20035030; PMCID: PMC2838546.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Myocardial survival signaling in response to stem cell transplantation. J Am Coll Surg. 2009 Apr; 208(4):607-13.
Li H, Malhotra D, Yeh CC, Tu R, Zhu BQ, Birger N, Wisneski A, Cha J, Karliner JS, Mann MJ. PMID: 19476797; PMCID: PMC2817986.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Sphingolipid signaling and treatment during remodeling of the uninfarcted ventricular wall after myocardial infarction. Am J Physiol Heart Circ Physiol. 2009 Apr; 296(4):H1193-9.
Yeh CC, Li H, Malhotra D, Huang MC, Zhu BQ, Goetzl EJ, Vessey DA, Karliner JS, Mann MJ. PMID: 19234089; PMCID: PMC2670694.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Surgical ventricular reconstruction in mice: elucidating potential targets for combined molecular/surgical intervention. J Thorac Cardiovasc Surg. 2009 Apr; 137(4):942-9.
Yeh CC, Malhotra D, Li H, Nicholas S, Tu R, Mann MJ. PMID: 19327522; PMCID: PMC2692719.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Cardiac transgenic matrix metalloproteinase-2 expression induces myxomatous valve degeneration: a potential model of mitral valve prolapse disease. Cardiovasc Pathol. 2009 Sep-Oct; 18(5):253-61.
Mahimkar R, Nguyen A, Mann M, Yeh CC, Zhu BQ, Karliner JS, Lovett DH. PMID: 18835790; PMCID: PMC3367668.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimals
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National Institutes of Health funding for cardiothoracic surgical research. J Thorac Cardiovasc Surg. 2008 Aug; 136(2):392-7; discussion 398-9.
Ratcliffe MB, Howard C, Mann M, del Nido P. PMID: 18692647.
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18 Fields:
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Humans
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National institutes of health funding for surgical research. Ann Surg. 2008 Feb; 247(2):217-21.
Mann M, Tendulkar A, Birger N, Howard C, Ratcliffe MB. PMID: 18216525.
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36 Fields:
Translation:
Humans
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Transcription factor decoys: a new model for disease intervention. Ann N Y Acad Sci. 2005 Nov; 1058:128-39.
Mann MJ. PMID: 16394132.
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16 Fields:
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HumansAnimalsCells
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Use of bivalirudin, a direct thrombin inhibitor, and its reversal with modified ultrafiltration during heart transplantation in a patient with heparin-induced thrombocytopenia. J Heart Lung Transplant. 2005 Feb; 24(2):222-5.
Mann MJ, Tseng E, Ratcliffe M, Strattman G, De Silva A, Demarco T, Achorn N, Moskalik W, Hoopes C. PMID: 15701441.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Reversal of direct thrombin inhibition after cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia. Anesth Analg. 2004 Jun; 98(6):1635-1639.
Stratmann G, deSilva AM, Tseng EE, Hambleton J, Balea M, Romo AJ, Mann MJ, Achorn NL, Moskalik WF, Hoopes CW. PMID: 15155316.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Cell cycle-dependent regulation of smooth muscle cell activation. Arterioscler Thromb Vasc Biol. 2004 May; 24(5):845-50.
Braun-Dullaeus RC, Mann MJ, Sedding DG, Sherwood SW, von der Leyen HE, Dzau VJ. PMID: 15016640.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Isolated pulmonary arteriovenous malformations requiring anatomic resection. J Thorac Cardiovasc Surg. 2004 Feb; 127(2):574-6.
Mann MJ, Kramer MJ, Hall TS, Anastassiou P, Katz J, Golden J, Jones K, Jablons DM. PMID: 14762372.
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Humans
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Novel strategies for the prevention of bypass graft failure. BioDrugs. 2004; 18(1):1-8.
Mann MJ. PMID: 14733603.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: implications for cell-based vascular therapy. Circulation. 2003 Nov 25; 108(21):2710-5.
Griese DP, Ehsan A, Melo LG, Kong D, Zhang L, Mann MJ, Pratt RE, Mulligan RC, Dzau VJ. PMID: 14597586.
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PubMed Mentions:
110 Fields:
Translation:
AnimalsCells
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Transcription factor decoys for the prevention of vein bypass graft failure. Am J Cardiovasc Drugs. 2003; 3(2):79-85.
Mann MJ, Conte MS. PMID: 14727934.
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PubMed Mentions:
5 Fields:
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HumansAnimalsCells
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Molecular approaches for the treatment of atherosclerosis. Cardiol Clin. 2002 Nov; 20(4):633-43.
Mann MJ, Dzau VJ. PMID: 12472049.
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1 Fields:
Translation:
Humans
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Genetic interventions for vein bypass graft disease: a review. J Vasc Surg. 2002 Nov; 36(5):1040-52.
Conte MS, Mann MJ, Simosa HF, Rhynhart KK, Mulligan RC. PMID: 12422116.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
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Endothelial healing in vein grafts: proliferative burst unimpaired by genetic therapy of neointimal disease. Circulation. 2002 Apr 09; 105(14):1686-92.
Ehsan A, Mann MJ, Dell'Acqua G, Tamura K, Braun-Dullaeus R, Dzau VJ. PMID: 11940548.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Gene therapy strategy for long-term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase gene. Circulation. 2002 Feb 05; 105(5):602-7.
Melo LG, Agrawal R, Zhang L, Rezvani M, Mangi AA, Ehsan A, Griese DP, Dell'Acqua G, Mann MJ, Oyama J, Yet SF, Layne MD, Perrella MA, Dzau VJ. PMID: 11827926.
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PubMed Mentions:
74 Fields:
Translation:
HumansAnimalsCells
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Experimental Models of Arteriovenous Grafting. . 2000 Nov 9; 0:61-78.
Ehsan EA, Mann MM, Dzau DV. .
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Gene Therapy in Cardiovascular Disease. . 2000 Oct 20; 183-201.
Dzau DV, Ehsan EA, Mann MM. .
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Vascular growth factors as an adjunct to surgical revascularization. ACC Current Journal Review. 2000 Jul 1; 9(4):43-46.
Mann MM, Ehsan EA, Dzau DV. .
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DNA transfer into vascular smooth muscle using fusigenic Sendai virus (HJV)-liposomes. . 1997 Jan 1; 3-12.
Mann MM, Morishita MR, Gibbons GG, von der Leyen vH, Dzau DV. .
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914-71 High Efficiency Gene Transfer into Atherosclerotic Lesions in Hypercholesterolemic Rabbit Carotid Arteries. Journal of the American College of Cardiology. 1995 Feb 1; 25(2):71a.
von der Leyen vH, Mann MM, Gibbons GG, Dzau DV. .
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901-90 In Vivo Genetic Engineering of Cardiac Cells: Intracoronary Administration of Antisense (AS) Oligonucleotides (ODN). Journal of the American College of Cardiology. 1995 Feb 1; 25(2):26a.
Ellison EK, Gibbons GG, Morishita MR, Mann MM, Kernoff KR, Dzau DV. .
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