Michael Oldham, PhD

Title(s)Associate Professor, Neurological Surgery
SchoolSchool of Medicine
Address1450 3rd Street
San Francisco CA 94158
Phone415-502-5498
ORCID ORCID Icon0000-0001-7633-6932 Additional info
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    Collapse Biography 
    Collapse Education and Training
    UCLA, Los Angeles, CAPhD06/2009Neuroscience
    Duke University, Durham, NCBS05/1992Psychology (major), Chemistry (minor)
    Collapse Awards and Honors
    UCSF2016  - 2017Weill Institute for Neurosciences Scholar Award
    UCSF2015  - 2016Program for Breakthrough Biomedical Research New Frontiers Research Award
    UCLA2008  - 2008Eva Kavan Prize for Excellence in Research on the Brain

    Collapse Overview 
    Collapse Overview
    I am an Assistant Professor in the Department of Neurological Surgery and Brain Tumor Research Center at UCSF. My lab uses novel computational and experimental strategies to study the molecular basis of cellular identity in the human brain in health and disease. Much of our work is motivated by a simple but powerful idea: by analyzing gene coexpression relationships in heterogeneous tissue samples, it is possible to isolate robust transcriptional signatures of distinct cell types and cellular processes in silico. More generally, we have found that the covariance structure of omics data contains an enormous amount of untapped information about the molecular and cellular organization of biological systems. We have developed a computational pipeline to extract this information and are applying it to samples from normal human brain samples and brain tumors. These efforts will produce mathematical definitions of neurobiological cell types under a range of conditions and reveal the critical molecular features that promote and maintain cellular identity in the human brain in health and disease.

    Collapse Research 
    Collapse Research Activities and Funding
    Multiscale transcriptional architecture of the human brain
    NIH R01MH123156May 1, 2020 - Mar 31, 2024
    Role: Principal Investigator
    Decoding the molecular basis of cellular identity in adult malignant gliomas
    NIH R01CA244621Dec 1, 2019 - Nov 30, 2024
    Role: Principal Investigator
    Peripheral blood RNA biomarkers of recovery after spinal cord injury
    NIH R21NS106981Aug 15, 2018 - Jul 31, 2021
    Role: Co-Investigator
    Decoding the molecular basis of cellular identity in the human brain
    NIH R01MH113896Dec 5, 2017 - Nov 30, 2022
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse Faculty Mentoring
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Nests of dividing neuroblasts sustain interneuron production for the developing human brain. Science. 2022 01 28; 375(6579):eabk2346. Paredes MF, Mora C, Flores-Ramirez Q, Cebrian-Silla A, Del Dosso A, Larimer P, Chen J, Kang G, Gonzalez Granero S, Garcia E, Chu J, Delgado R, Cotter JA, Tang V, Spatazza J, Obernier K, Ferrer Lozano J, Vento M, Scott J, Studholme C, Nowakowski TJ, Kriegstein AR, Oldham MC, Hasenstaub A, Garcia-Verdugo JM, Alvarez-Buylla A, Huang EJ. PMID: 35084970; PMCID: PMC8887556.
      View in: PubMed   Mentions:
    2. ECOA-5. Integrative 3D spatial characterization of genomic and epigenomic intratumoral heterogeneity in glioblastoma. Neuro-Oncology Advances. 2021 Jul 5; 3(Supplement_2):ii2-ii2. Mathur MR, Wang WQ, Schupp SP, Hilz HS, Hong HC, Smirnov SI, Lafontaine LM, Nair ND, Iyyanaki IS, Phillips PJ, Chang CS, Li LY, Lupo LJ, Oldham OM, Yue YF, Costello CJ. .
      View in: Publisher Site   Mentions:
    3. ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects. J Clin Invest. 2021 04 01; 131(7). Qiu H, Lee S, Shang Y, Wang WY, Au KF, Kamiya S, Barmada SJ, Finkbeiner S, Lui H, Carlton CE, Tang AA, Oldham MC, Wang H, Shorter J, Filiano AJ, Roberson ED, Tourtellotte WG, Chen B, Tsai LH, Huang EJ. PMID: 33792567; PMCID: PMC8011883.
      View in: PubMed   Mentions:    Fields:    
    4. Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus. J Neurosci. 2021 03 24; 41(12):2554-2565. Sorrells SF, Paredes MF, Zhang Z, Kang G, Pastor-Alonso O, Biagiotti S, Page CE, Sandoval K, Knox A, Connolly A, Huang EJ, Garcia-Verdugo JM, Oldham MC, Yang Z, Alvarez-Buylla A. PMID: 33762407; PMCID: PMC8018729.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    5. Diagnostic blood RNA profiles for human acute spinal cord injury. J Exp Med. 2021 03 01; 218(3). Kyritsis N, Torres-Espín A, Schupp PG, Huie JR, Chou A, Duong-Fernandez X, Thomas LH, Tsolinas RE, Hemmerle DD, Pascual LU, Singh V, Pan JZ, Talbott JF, Whetstone WD, Burke JF, DiGiorgio AM, Weinstein PR, Manley GT, Dhall SS, Ferguson AR, Oldham MC, Bresnahan JC, Beattie MS. PMID: 33512429; PMCID: PMC7852457.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. Machine intelligence identifies soluble TNFa as a therapeutic target for spinal cord injury. Sci Rep. 2021 02 09; 11(1):3442. Huie JR, Ferguson AR, Kyritsis N, Pan JZ, Irvine KA, Nielson JL, Schupp PG, Oldham MC, Gensel JC, Lin A, Segal MR, Ratan RR, Bresnahan JC, Beattie MS. PMID: 33564058; PMCID: PMC7873211.
      View in: PubMed   Mentions: 1     Fields:    
    7. Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module. Nat Neurosci. 2019 11; 22(11):1892-1902. Munji RN, Soung AL, Weiner GA, Sohet F, Semple BD, Trivedi A, Gimlin K, Kotoda M, Korai M, Aydin S, Batugal A, Cabangcala AC, Schupp PG, Oldham MC, Hashimoto T, Noble-Haeusslein LJ, Daneman R. PMID: 31611708; PMCID: PMC6858546.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    8. MicroRNA Ratios Distinguish Melanomas from Nevi. J Invest Dermatol. 2020 01; 140(1):164-173.e7. Torres R, Lang UE, Hejna M, Shelton SJ, Joseph NM, Shain AH, Yeh I, Wei ML, Oldham MC, Bastian BC, Judson-Torres RL. PMID: 31580842; PMCID: PMC6926155.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    9. Immunopeptidomics and Peptide Expression Profiles to Develop T-Cell Receptors Against Glioma-Associated Antigens. Neurosurgery. 2019 Sep 1; 66(Supplement_1). Carrera CD, Hayes HJ, Müller MS, Watchmaker WP, Shelton SS, Hilf HN, Weinschenk WT, Schoor SO, Kohanbash KG, Oldham OM, Costello CJ, Singh SH, Okada OH. .
      View in: Publisher Site   Mentions:
    10. 786 A machine-learning classifier trained with microRNA ratios to distinguish melanomas from nevi. Journal of Investigative Dermatology. 2019 May 1; 139(5):s136. Torres TR, Lang LU, Joseph JN, Shain SA, Yeh YI, Wei WM, Oldham OM, Bastian BB, Judson-Torres JR. .
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    11. Does Adult Neurogenesis Persist in the Human Hippocampus? Cell Stem Cell. 2018 12 06; 23(6):780-781. Paredes MF, Sorrells SF, Cebrian-Silla A, Sandoval K, Qi D, Kelley KW, James D, Mayer S, Chang J, Auguste KI, Chang EF, Gutierrez Martin AJ, Kriegstein AR, Mathern GW, Oldham MC, Huang EJ, Garcia-Verdugo JM, Yang Z, Alvarez-Buylla A. PMID: 30526879; PMCID: PMC6800191.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    12. Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes. Nat Neurosci. 2018 09; 21(9):1171-1184. Kelley KW, Nakao-Inoue H, Molofsky AV, Oldham MC. PMID: 30154505; PMCID: PMC6192711.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    13. Sequencing Diversity One Cell at a Time. Cell. 2018 08 09; 174(4):777-779. Oldham MC, Kreitzer AC. PMID: 30096308.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    14. Secretagogin is Expressed by Developing Neocortical GABAergic Neurons in Humans but not Mice and Increases Neurite Arbor Size and Complexity. Cereb Cortex. 2018 06 01; 28(6):1946-1958. Raju CS, Spatazza J, Stanco A, Larimer P, Sorrells SF, Kelley KW, Nicholas CR, Paredes MF, Lui JH, Hasenstaub AR, Kriegstein AR, Alvarez-Buylla A, Rubenstein JL, Oldham MC. PMID: 28449024; PMCID: PMC6019052.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    15. 1220 MicroRNA signature distinguishing nevi from primary melanoma. Journal of Investigative Dermatology. 2018 May 1; 138(5):s207. Torres TR, Lang LU, Shelton SS, Yeniay YY, Joseph JN, Shain SA, Yeh YI, Oldham OM, Wei WM, Bastian BB, Judson JR. .
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    16. A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment. Cancer Cell. 2018 05 14; 33(5):874-889.e7. Griveau A, Seano G, Shelton SJ, Kupp R, Jahangiri A, Obernier K, Krishnan S, Lindberg OR, Yuen TJ, Tien AC, Sabo JK, Wang N, Chen I, Kloepper J, Larrouquere L, Ghosh M, Tirosh I, Huillard E, Alvarez-Buylla A, Oldham MC, Persson AI, Weiss WA, Batchelor TT, Stemmer-Rachamimov A, Suvà ML, Phillips JJ, Aghi MK, Mehta S, Jain RK, Rowitch DH. PMID: 29681511; PMCID: PMC6211172.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    17. Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults. Nature. 2018 03 15; 555(7696):377-381. Sorrells SF, Paredes MF, Cebrian-Silla A, Sandoval K, Qi D, Kelley KW, James D, Mayer S, Chang J, Auguste KI, Chang EF, Gutierrez AJ, Kriegstein AR, Mathern GW, Oldham MC, Huang EJ, Garcia-Verdugo JM, Yang Z, Alvarez-Buylla A. PMID: 29513649; PMCID: PMC6179355.
      View in: PubMed   Mentions: 335     Fields:    Translation:HumansAnimalsCells
    18. IMMU-52. SELECTION OF GLIOMA T-CELL THERAPY TARGETS BASED ON THE ANALYSIS OF TUMOR IMMUNOPEPTIDOME AND EXPRESSION PROFILES. Neuro-Oncology. 2017 Nov 6; 19(suppl_6):vi124-vi124. Carrera CD, Hayes HJ, Mueller MS, Shelton SS, Weinschenk WT, Song SC, Fritsche FJ, Schoor SO, Kuttruff-Coqui KS, Hilf HN, Kohanbash KG, Watchmaker WP, Oldham OM, Costello CJ, Singh SH, Okada OH. .
      View in: Publisher Site   Mentions:
    19. GENE-33. THE 3D EVOLUTION AND IN VIVO GROWTH PATTERNS OF GLIOMA CELL POPULATIONS. Neuro-Oncology. 2017 Nov 6; 19(suppl_6):vi99-vi99. Hilz HS, Shelton SS, Jalbert JL, Wong WH, Mazor MT, Hong HC, Hayes HJ, Luks LT, Bengtsson BH, Molinaro MA, McDermott MM, Berger BM, Lim LD, Diaz DA, Phillips PJ, Chang CS, Nelson NS, Oldham OM, Costello CJ. .
      View in: Publisher Site   Mentions:
    20. Genetic Characterization of Stromal Cells in High Grade Gliomas. International Journal of Radiation Oncology • Biology • Physics. 2017 Oct 1; 99(2):e68. Choi CS, Hayes HJ, Shelton SS, Jones JL, Mazor MT, Fouse FS, Oldham OM, Costello CJ. .
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    21. Correction: Pleiotropic Mechanisms Indicated for Sex Differences in Autism. PLoS Genet. 2017 Jun; 13(6):e1006831. Mitra I, Tsang K, Ladd-Acosta C, Croen LA, Aldinger KA, Hendren RL, Traglia M, Lavillaureix A, Zaitlen N, Oldham MC, Levitt P, Nelson S, Amaral DG, Hertz-Picciotto I, Fallin MD, Weiss LA. PMID: 28591140; PMCID: PMC5462340.
      View in: PubMed   Mentions: 1     Fields:    
    22. Resolving stem and progenitor cells in the adult mouse incisor through gene co-expression analysis. Elife. 2017 05 05; 6. Seidel K, Marangoni P, Tang C, Houshmand B, Du W, Maas RL, Murray S, Oldham MC, Klein OD. PMID: 28475038; PMCID: PMC5419740.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    23. An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice. Cell Stem Cell. 2017 07 06; 21(1):91-106.e6. Hu JK, Du W, Shelton SJ, Oldham MC, DiPersio CM, Klein OD. PMID: 28457749; PMCID: PMC5501749.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    24. Pleiotropic Mechanisms Indicated for Sex Differences in Autism. PLoS Genet. 2016 11; 12(11):e1006425. Mitra I, Tsang K, Ladd-Acosta C, Croen LA, Aldinger KA, Hendren RL, Traglia M, Lavillaureix A, Zaitlen N, Oldham MC, Levitt P, Nelson S, Amaral DG, Hertz-Picciotto I, Fallin MD, Weiss LA. PMID: 27846226; PMCID: PMC5147776.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    25. GENT-15. INTEGRATED MOLECULAR PROFILING OF HUMAN BRAIN TUMORS THROUGH MULTIOMIC ANALYSIS OF SERIAL SECTIONS (MASS). Neuro-Oncology. 2016 Nov 1; 18(suppl_6):vi76-vi77. Shelton SS, Johnson JB, Mazor MT, Potts PM, McDermott MM, Huang HE, Lim LD, Pieper PR, Berger BM, Phillips PJ, Costello CJ, Oldham OM. .
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    26. Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation. Cell. 2016 May 05; 165(4):921-35. Lui H, Zhang J, Makinson SR, Cahill MK, Kelley KW, Huang HY, Shang Y, Oldham MC, Martens LH, Gao F, Coppola G, Sloan SA, Hsieh CL, Kim CC, Bigio EH, Weintraub S, Mesulam MM, Rademakers R, Mackenzie IR, Seeley WW, Karydas A, Miller BL, Borroni B, Ghidoni R, Farese RV, Paz JT, Barres BA, Huang EJ. PMID: 27114033; PMCID: PMC4860138.
      View in: PubMed   Mentions: 217     Fields:    Translation:HumansAnimalsCells
    27. Transcriptional architecture of the human brain. Nat Neurosci. 2015 Dec; 18(12):1699-701. Kelley KW, Oldham MC. PMID: 26605877.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    28. MPTH-29CONNECTING MUTANT GENOTYPES TO ABERRANT TRANSCRIPTIONAL SIGNATURES ACROSS SERIAL SECTIONS OF A HUMAN TUMOR. Neuro-Oncology. 2015 Nov 1; 17(suppl_5):v144-v145. Shelton SS, Johnson JB, Mazor MT, Potts PM, McDermott MM, Huang HE, Lim LD, Pieper PR, Berger BM, Phillips PJ, Costello CJ, Oldham OM. .
      View in: Publisher Site   Mentions:
    29. ANGI-04Olig2 REGULATES Wnt7b EXPRESSION AND VASCULATURE CHARACTERISTICS IN GLIOMA. Neuro-Oncology. 2015 Nov 1; 17(suppl_5):v41-v41. Griveau GA, Shelton SS, Tien TA, Seano SG, Yuen YT, Sabo SJ, Lau LJ, Jahangiri JA, Huillard HE, Phillips PJ, Persson PA, Oldham OM, Weiss WW, Aghi AM, Stiles SC, Mehta MS, Batchelor BT, Jain JR, Rowitch RD. .
      View in: Publisher Site   Mentions:
    30. Molecular identity of human outer radial glia during cortical development. Cell. 2015 Sep 24; 163(1):55-67. Pollen AA, Nowakowski TJ, Chen J, Retallack H, Sandoval-Espinosa C, Nicholas CR, Shuga J, Liu SJ, Oldham MC, Diaz A, Lim DA, Leyrat AA, West JA, Kriegstein AR. PMID: 26406371; PMCID: PMC4583716.
      View in: PubMed   Mentions: 226     Fields:    Translation:HumansAnimalsCells
    31. miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability. Cell Rep. 2015 Aug 04; 12(5):760-73. Parchem RJ, Moore N, Fish JL, Parchem JG, Braga TT, Shenoy A, Oldham MC, Rubenstein JL, Schneider RA, Blelloch R. PMID: 26212322; PMCID: PMC4741278.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    32. Radial glia require PDGFD-PDGFRβ signalling in human but not mouse neocortex. Nature. 2014 Nov 13; 515(7526):264-8. Lui JH, Nowakowski TJ, Pollen AA, Javaherian A, Kriegstein AR, Oldham MC. PMID: 25391964; PMCID: PMC4231536.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    33. Analysis of Mll1 deficiency identifies neurogenic transcriptional modules and Brn4 as a factor for direct astrocyte-to-neuron reprogramming. Neurosurgery. 2014 Oct; 75(4):472-82; discussion 482. Potts MB, Siu JJ, Price JD, Salinas RD, Cho MJ, Ramos AD, Hahn J, Margeta M, Oldham MC, Lim DA. PMID: 24887289; PMCID: PMC4420187.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    34. DISTINCT AND SEPARABLE ROLES FOR HISTONE METHYLTRANSFERASE EZH2 IN NEUROGENIC ASTROCYTES. Neuro-Oncology. 2014 Jul 1; 16(suppl_3):iii17-iii17. Lim LD, Hwang HW, Salinas SR, Siu SJ, Kelley KK, Delgado DR, Paredes PM, Alvarez-Buylla AA, Oldham OM, Lim LD. .
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    35. Distinct and separable roles for EZH2 in neurogenic astroglia. Elife. 2014 May 27; 3:e02439. Hwang WW, Salinas RD, Siu JJ, Kelley KW, Delgado RN, Paredes MF, Alvarez-Buylla A, Oldham MC, Lim DA. PMID: 24867641; PMCID: PMC4032491.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    36. Two miRNA clusters reveal alternative paths in late-stage reprogramming. Cell Stem Cell. 2014 May 01; 14(5):617-31. Parchem RJ, Ye J, Judson RL, LaRussa MF, Krishnakumar R, Blelloch A, Oldham MC, Blelloch R. PMID: 24630794; PMCID: PMC4305531.
      View in: PubMed   Mentions: 44     Fields:    Translation:Animals
    37. ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects. J Clin Invest. 2014 Mar; 124(3):981-99. Qiu H, Lee S, Shang Y, Wang WY, Au KF, Kamiya S, Barmada SJ, Finkbeiner S, Lui H, Carlton CE, Tang AA, Oldham MC, Wang H, Shorter J, Filiano AJ, Roberson ED, Tourtellotte WG, Chen B, Tsai LH, Huang EJ. PMID: 24509083; PMCID: PMC3938263.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    38. Expression profiling of Aldh1l1-precursors in the developing spinal cord reveals glial lineage-specific genes and direct Sox9-Nfe2l1 interactions. Glia. 2013 Sep; 61(9):1518-32. Molofsky AV, Glasgow SM, Chaboub LS, Tsai HH, Murnen AT, Kelley KW, Fancy SP, Yuen TJ, Madireddy L, Baranzini S, Deneen B, Rowitch DH, Oldham MC. PMID: 23840004; PMCID: PMC3909648.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    39. Integration of genome-wide approaches identifies lncRNAs of adult neural stem cells and their progeny in vivo. Cell Stem Cell. 2013 May 02; 12(5):616-28. Ramos AD, Diaz A, Nellore A, Delgado RN, Park KY, Gonzales-Roybal G, Oldham MC, Song JS, Lim DA. PMID: 23583100; PMCID: PMC3662805.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    40. Human-specific regulation of MeCP2 levels in fetal brains by microRNA miR-483-5p. Genes Dev. 2013 Mar 01; 27(5):485-90. Han K, Gennarino VA, Lee Y, Pang K, Hashimoto-Torii K, Choufani S, Raju CS, Oldham MC, Weksberg R, Rakic P, Liu Z, Zoghbi HY. PMID: 23431031; PMCID: PMC3605462.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    41. Human-specific transcriptional networks in the brain. Neuron. 2012 Aug 23; 75(4):601-17. Konopka G, Friedrich T, Davis-Turak J, Winden K, Oldham MC, Gao F, Chen L, Wang GZ, Luo R, Preuss TM, Geschwind DH. PMID: 22920253; PMCID: PMC3645834.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansAnimals
    42. Network methods for describing sample relationships in genomic datasets: application to Huntington's disease. BMC Syst Biol. 2012 Jun 12; 6:63. Oldham MC, Langfelder P, Horvath S. PMID: 22691535; PMCID: PMC3441531.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    43. Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling. Neuron. 2011 Sep 22; 71(6):1030-42. Rosen EY, Wexler EM, Versano R, Coppola G, Gao F, Winden KD, Oldham MC, Martens LH, Zhou P, Farese RV, Geschwind DH. PMID: 21943601; PMCID: PMC3633414.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    44. Neurons show distinctive DNA methylation profile and higher interindividual variations compared with non-neurons. Genome Res. 2011 May; 21(5):688-96. Iwamoto K, Bundo M, Ueda J, Oldham MC, Ukai W, Hashimoto E, Saito T, Geschwind DH, Kato T. PMID: 21467265; PMCID: PMC3083085.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    45. Is my network module preserved and reproducible? PLoS Comput Biol. 2011 Jan 20; 7(1):e1001057. Langfelder P, Luo R, Oldham MC, Horvath S. PMID: 21283776; PMCID: PMC3024255.
      View in: PubMed   Mentions: 344     Fields:    Translation:HumansAnimals
    46. Is human blood a good surrogate for brain tissue in transcriptional studies? BMC Genomics. 2010 Oct 20; 11:589. Cai C, Langfelder P, Fuller TF, Oldham MC, Luo R, van den Berg LH, Ophoff RA, Horvath S. PMID: 20961428; PMCID: PMC3091510.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    47. Detecting network modules in fMRI time series: a weighted network analysis approach. Neuroimage. 2010 Oct 01; 52(4):1465-76. Mumford JA, Horvath S, Oldham MC, Langfelder P, Geschwind DH, Poldrack RA. PMID: 20553896; PMCID: PMC3632300.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    48. The organization of the transcriptional network in specific neuronal classes. Mol Syst Biol. 2009; 5:291. Winden KD, Oldham MC, Mirnics K, Ebert PJ, Swan CH, Levitt P, Rubenstein JL, Horvath S, Geschwind DH. PMID: 19638972; PMCID: PMC2724976.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    49. Functional Connectivity Using Weighted Voxel Coexpression Network Analysis. NeuroImage. 2009 Jul 1; 47:s169. Mumford MJ, Poldrack PR, Oldham OM, Geshwind GD, Langfelder LP, Horvath HS. .
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    50. Gene Expression in the Evolution of the Human Brain. Encyclopedia of Neuroscience. 2009 Jan 1; (Nature Reviews Genetics52004):597-603. Oldham OM, Geschwind GD. .
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    51. Functional organization of the transcriptome in human brain. Nat Neurosci. 2008 Nov; 11(11):1271-82. Oldham MC, Konopka G, Iwamoto K, Langfelder P, Kato T, Horvath S, Geschwind DH. PMID: 18849986; PMCID: PMC2756411.
      View in: PubMed   Mentions: 372     Fields:    Translation:HumansCells
    52. A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging. J Neurosci. 2008 Feb 06; 28(6):1410-20. Miller JA, Oldham MC, Geschwind DH. PMID: 18256261; PMCID: PMC2902235.
      View in: PubMed   Mentions: 163     Fields:    Translation:HumansCells
    53. Genome-wide analyses of human perisylvian cerebral cortical patterning. Proc Natl Acad Sci U S A. 2007 Nov 06; 104(45):17849-54. Abrahams BS, Tentler D, Perederiy JV, Oldham MC, Coppola G, Geschwind DH. PMID: 17978184; PMCID: PMC2077018.
      View in: PubMed   Mentions: 88     Fields:    Translation:Humans
    54. Identification of the transcriptional targets of FOXP2, a gene linked to speech and language, in developing human brain. Am J Hum Genet. 2007 Dec; 81(6):1144-57. Spiteri E, Konopka G, Coppola G, Bomar J, Oldham M, Ou J, Vernes SC, Fisher SE, Ren B, Geschwind DH. PMID: 17999357; PMCID: PMC2276350.
      View in: PubMed   Mentions: 115     Fields:    Translation:HumansAnimalsCells
    55. Conservation and evolution of gene coexpression networks in human and chimpanzee brains. Proc Natl Acad Sci U S A. 2006 Nov 21; 103(47):17973-8. Oldham MC, Horvath S, Geschwind DH. PMID: 17101986; PMCID: PMC1693857.
      View in: PubMed   Mentions: 276     Fields:    Translation:HumansAnimals
    56. Comparative genomics: grasping human transcriptome evolution: what does it all mean? Heredity (Edinb). 2006 May; 96(5):339-40. Oldham MC, Geschwind DH. PMID: 16552432.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    57. Deconstructing language by comparative gene expression: from neurobiology to microarray. Genes Brain Behav. 2006; 5 Suppl 1:54-63. Oldham MC, Geschwind DH. PMID: 16417618.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
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