Michael Podolsky, MD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
Address555 Mission Bay Blvd South
San Francisco CA 94158
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    Fibrosis is usually defined as the excess accumulation of extracellular matrix that replaces normal tissue architecture. Yet, this can actually be part of the physiologic process of wound healing. The distinction between normal wound healing and pathological fibrosis is the persistence of fibrosis. The biology that underlies whether fibrosis resolves or persists still remains incompletely understood. My research is focused on understanding the resolution of fibrosis, both how this phenomenon is regulated in health and dysregulated in disease. In particular, this includes the study of age-related pulmonary fibrosis and mechanisms of extracellular matrix turnover.

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    Role of Endo180 Regulation in Tissue Fibrosis
    NIH K08HL145015Aug 15, 2019 - Jul 31, 2024
    Role: Principal Investigator
    Cell-based control of collagen uptake in health and in fibrotic disease
    NIH F32HL136062Jan 9, 2018 - Jan 8, 2020
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Autoregulation of insulin receptor signaling through MFGE8 and the avß5 integrin. Proc Natl Acad Sci U S A. 2021 May 04; 118(18). Datta R, Lizama CO, Soltani AK, Mckleroy W, Podolsky MJ, Yang CD, Huynh TL, Cautivo KM, Wang B, Koliwad SK, Abumrad NA, Atabai K. PMID: 33903257.
      View in: PubMed   Mentions:    Fields:    
    2. You Say You Want a Resolution (of Fibrosis). Am J Respir Cell Mol Biol. 2020 10; 63(4):424-435. Atabai K, Yang CD, Podolsky MJ. PMID: 32640171.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    3. Age-dependent regulation of cell-mediated collagen turnover. JCI Insight. 2020 05 21; 5(10). Podolsky MJ, Yang CD, Valenzuela CL, Datta R, Huang SK, Nishimura SL, Dallas SL, Wolters PJ, Le Saux CJ, Atabai K. PMID: 32315288.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    4. Fat fibrosis: friend or foe? JCI Insight. 2018 10 04; 3(19). Datta R, Podolsky MJ, Atabai K. PMID: 30282827.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    5. Cell division cycle 7 kinase is a negative regulator of cell-mediated collagen degradation. . 2018 09 01; 315(3):L360-L370. Podolsky MJ, Gupta D, Ha A, Ta R, Khalifeh-Soltani A, McKleroy W, Datta R, Sheppard D, Atabai K. PMID: 29792348.
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    6. The Mfge8-a8ß1-PTEN pathway regulates airway smooth muscle contraction in allergic inflammation. FASEB J. 2018 May 15; fj201800109R. Khalifeh-Soltani A, Gupta D, Ha A, Podolsky MJ, Datta R, Atabai K. PMID: 29763381.
      View in: PubMed   Mentions: 5     Fields:    
    7. Mfge8 regulates enterocyte lipid storage by promoting enterocyte triglyceride hydrolase activity. JCI Insight. 2016 11 03; 1(18):e87418. Khalifeh-Soltani A, Gupta D, Ha A, Iqbal J, Hussain M, Podolsky MJ, Atabai K. PMID: 27812539.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    8. Loss Of Fatty Acid Synthase Increases The Severity Of Lung Fibrosis By Preventing Collagen Resorption. QJM. 2016 Sep 1; 109(suppl_1):s20-s21. Kamran Atabai, Michael Podolsky, Donald Mccarthy. .
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    9. a8ß1 integrin regulates nutrient absorption through an Mfge8-PTEN dependent mechanism. Elife. 2016 04 19; 5. Khalifeh-Soltani A, Ha A, Podolsky MJ, McCarthy DA, McKleroy W, Azary S, Sakuma S, Tharp KM, Wu N, Yokosaki Y, Hart D, Stahl A, Atabai K. PMID: 27092791.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
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