Fibrosis is usually defined as the excess accumulation of extracellular matrix that replaces normal tissue architecture. Yet, this can actually be part of the physiologic process of wound healing. The distinction between normal wound healing and pathological fibrosis is the persistence of fibrosis. The biology that underlies whether fibrosis resolves or persists still remains incompletely understood. My research is focused on understanding the resolution of fibrosis, both how this phenomenon is regulated in health and dysregulated in disease. In particular, this includes the study of age-related pulmonary fibrosis and mechanisms of extracellular matrix turnover.