Micquel Little joined UCSF Library in 2019 as Associate University Librarian for Research and Learning. In 2024, Micquel was promoted to Deputy University Librarian.

In this role, she provides leadership, vision, strategic direction, and coordination in developing, assessing, and sustaining the Library’s services and spaces that support teaching, research, and clinical activities of UCSF faculty, students, and staff. Micquel oversees multiple research and learning programs at the UCSF Library, ensuring consistent direction, leadership, administration of learning activities, processes, evaluations, and resource management. She leads strategic program improvements to increase educational quality and operational efficiency through managing program leaders in the following areas: Access Services, Data Science & Open Scholarship, Education Research, Makers Lab, Instructional Design, Innovative Technologies of the Library, Outreach and Marketing, User Experience, Technology Systems and Strategy, and clinical research support at the UCSF Benioff Children's Hospital Oakland and Zuckerberg San Francisco General Hospital campuses.