Misung Han, PhD

Title(s)Assistant Researcher, Radiology
SchoolSchool of Medicine
Address1700 4th St
San Francisco CA 94158
Phone415-514-9655
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    Collapse Biography 
    Collapse Education and Training
    Korea Advanced Institute of Science and Technology, Daejeon, KoreaB.S.08/2002Electrical Engineering
    Stanford University, Stanford, CAM.S.08/2004Electrical Engineering
    Stanford University, Stanford, CAPh.D.08/2010Electrical Engineering
    University of California, San Francisco, San Francisco, CAPostdoctoral Training09/2014Radiology and Biomedical Imaging
    Collapse Awards and Honors
    ISMRM2016  - 2018Distinguished Reviewer, Journal of Magnetic Resonance Imaging
    ISMRM2019  - 2019Distinguished Reviewer, Magnetic Resonance in Medicine
    ISMRM2018  - 2020Reviewer Certificate, NMR in Biomedicine
    ISMRM2012Magna Cum Laude Award

    Collapse Overview 
    Collapse Overview
    Misung Han, Ph.D, is a Professional Assistant Researcher in the Department of Radiology and Biomedical Imaging at UCSF. She has developed various MRI techniques ranging over MRI acquisition, reconstruction, and quantification for breast, musculoskeletal, and brain applications both at Stanford (as a graduate student) and at UCSF. At UCSF, she primarily belongs to the Musculoskeletal and Quantitative Imaging Research Group. She has focused on developing new MRI methods for depicting high-resolution structure and quantifying tissue parameters in musculoskeletal tissues including semi-solid/solid tissues. In addition, she has worked with other research groups, applying her technical expertise for diverse clinical applications. By working with the Neuro Imaging group, she developed accelerated DSC perfusion imaging techniques for brain tumor quantification and multiband TOF/SWI techniques to assess vasculature and vascular injury. By working with the Focused Ultrasound Lab, she developed UTE temperature mapping methods that have potentials to assess heat deposition in cortical bone.

    She is a recipient of an NIAMS K01 grant to develop MRI techniques to comprehensively assess rotator cuff pathology. She has great interests in developing novel, efficient MRI techniques to improve diagnostic capability and to quantify image biomarkers associated with degeneration.

    Collapse Research 
    Collapse Research Activities and Funding
    Quantitative shoulder MRI for evaluating rotator cuff pathology
    NIH K01AR075895Jul 1, 2020 - Jun 30, 2025
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Magnetization-prepared spoiled gradient-echo snapshot imaging for efficient measurement of R2 -R1ρ in knee cartilage. Magn Reson Med. 2021 Sep 30. Han M, Tibrewala R, Bahroos E, Pedoia V, Majumdar S. PMID: 34590728.
      View in: PubMed   Mentions:    Fields:    
    2. Measurement of vertebral endplate bone marrow lesion (Modic change) composition with water-fat MRI and relationship to patient-reported outcome measures. Eur Spine J. 2021 Sep; 30(9):2549-2556. Fields AJ, Ballatori A, Han M, Bailey JF, McCormick ZL, O'Neill CW, Demir-Deviren S, Krug R, Lotz JC. PMID: 33547944.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Simultaneous multi-slice spin- and gradient-echo dynamic susceptibility-contrast perfusion-weighted MRI of gliomas. NMR Biomed. 2021 01; 34(1):e4399. Han M, Yang B, Fernandez B, Lafontaine M, Alcaide-Leon P, Jakary A, Burns BL, Morrison MA, Villanueva-Meyer JE, Chang SM, Banerjee S, Lupo JM. PMID: 32844496.
      View in: PubMed   Mentions: 1     Fields:    
    4. Investigating the Association of Metabolic Biomarkers With Knee Cartilage Composition and Structural Abnormalities Using MRI: A Pilot Study. Cartilage. 2020 Aug 06; 1947603520946376. Ashmeik W, Baal JD, Foreman SC, Joseph GB, Bahroos E, Han M, Krug R, Link TM. PMID: 32757831.
      View in: PubMed   Mentions:    Fields:    
    5. Evaluation of human cartilage endplate composition using MRI: Spatial variation, association with adjacent disc degeneration, and in vivo repeatability. J Orthop Res. 2021 07; 39(7):1470-1478. Wang L, Han M, Wong J, Zheng P, Lazar AA, Krug R, Fields AJ. PMID: 32592504.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    6. Bone material analogues for PET/MRI phantoms. Med Phys. 2020 Jun; 47(5):2161-2170. Chandramohan D, Cao P, Han M, An H, Sunderland JJ, Kinahan PE, Laforest R, Hope TA, Larson PEZ. PMID: 32034945.
      View in: PubMed   Mentions: 2     Fields:    
    7. Associations between vertebral body fat fraction and intervertebral disc biochemical composition as assessed by quantitative MRI. Journal of Magnetic Resonance Imaging. 2019 Oct 1; 50(4):spcone-spcone. Krug KR, Joseph JG, Han HM, Fields FA, Cheung CJ, Mundada MM, Bailey BJ, Rochette RA, Ballatori BA, McCulloch MC, McCormick MZ, O'Neill OC, Link LT, Lotz LJ. .
      View in: Publisher Site   Mentions:
    8. Patients with Type 2 Diabetes Exhibit a More Mineralized Deep Cartilage Layer Compared with Nondiabetic Controls: A Pilot Study. Cartilage. 2019 Aug 27; 1947603519870853. Foreman SC, Ashmeik W, Baal JD, Han M, Bahroos E, von Schacky CE, Carl M, Krug R, Joseph GB, Link TM. PMID: 31455093.
      View in: PubMed   Mentions:    Fields:    
    9. The Relationship Between Endplate Pathology and Patient-reported Symptoms for Chronic Low Back Pain Depends on Lumbar Paraspinal Muscle Quality. Spine (Phila Pa 1976). 2019 Jul 15; 44(14):1010-1017. Bailey JF, Fields AJ, Ballatori A, Cohen D, Jain D, Coughlin D, O'Neill C, McCormick Z, Han M, Krug R, Demir-Deviren S, Lotz JC. PMID: 30896590.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    10. Cortical bone vessel identification and quantification on contrast-enhanced MR images. Quant Imaging Med Surg. 2019 Jun; 9(6):928-941. Wu PH, Gibbons M, Foreman SC, Carballido-Gamio J, Han M, Krug R, Liu J, Link TM, Kazakia GJ. PMID: 31367547.
      View in: PubMed   Mentions:
    11. Patients with type 2 diabetes exhibit a more calcified deep cartilage layer compared to nondiabetic controls: a pilot study. Osteoarthritis and Cartilage. 2019 Apr 1; 27:s148. Foreman FS, Ashmeik AW, Baal BJ, Bahroos BE, Krug KR, Han HM, Joseph JG, Link LT. .
      View in: Publisher Site   Mentions:
    12. Associations between vertebral body fat fraction and intervertebral disc biochemical composition as assessed by quantitative MRI. J Magn Reson Imaging. 2019 10; 50(4):1219-1226. Krug R, Joseph GB, Han M, Fields A, Cheung J, Mundada M, Bailey J, Rochette A, Ballatori A, McCulloch CE, McCormick Z, O'Neill C, Link TM, Lotz J. PMID: 30701594.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    13. Cartilage Endplate Thickness Variation Measured by Ultrashort Echo-Time MRI Is Associated With Adjacent Disc Degeneration. Spine (Phila Pa 1976). 2018 05 15; 43(10):E592-E600. Berg-Johansen B, Han M, Fields AJ, Liebenberg EC, Lim BJ, Larson PE, Gunduz-Demir C, Kazakia GJ, Krug R, Lotz JC. PMID: 28984733.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    14. Quantification of 89 Zr-Iron oxide nanoparticle biodistribution using PET-MR and ultrashort TE sequences. J Magn Reson Imaging. 2018 12; 48(6):1717-1720. Jordan CD, Han M, Kondapavulur S, Vera DB, Neumann KD, Moore T, Stillson C, Krug R, Behr S, Seo Y, VanBrocklin HF, Larson PEZ, Wilson M, Martin AJ, Hetts SW. PMID: 29761624.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    15. Trabecular bone microstructure is impaired in the proximal femur of human immunodeficiency virus-infected men with normal bone mineral density. Quant Imaging Med Surg. 2018 Feb; 8(1):5-13. Kazakia GJ, Carballido-Gamio J, Lai A, Nardo L, Facchetti L, Pasco C, Zhang CA, Han M, Parrott AH, Tien P, Krug R. PMID: 29541618.
      View in: PubMed   Mentions: 1  
    16. In vivo characterization of brain ultrashort-T2 components. Magn Reson Med. 2018 08; 80(2):726-735. Boucneau T, Cao P, Tang S, Han M, Xu D, Henry RG, Larson PEZ. PMID: 29194734.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    17. T2-based temperature monitoring in bone marrow for MR-guided focused ultrasound. J Ther Ultrasound. 2016; 4:26. Ozhinsky E, Han M, Bucknor M, Krug R, Rieke V. PMID: 27882240.
      View in: PubMed   Mentions: 2  
    18. Ultrashort echo time and zero echo time MRI at 7T. MAGMA. 2016 Jun; 29(3):359-70. Larson PE, Han M, Krug R, Jakary A, Nelson SJ, Vigneron DB, Henry RG, McKinnon G, Kelley DA. PMID: 26702940.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    19. Relationship between temperature and T2 in subcutaneous fat and bone marrow at 3T. Journal of Therapeutic Ultrasound. 2015 Dec 1; 3(Suppl 1):p89. Ozhinsky OE, Han HM, Scott SS, Diederich DC, Rieke RV. .
      View in: Publisher Site   Mentions:
    20. Assessing temperature dependence of T1 in cortical bone using ultrashort echo-time MRI. Journal of Therapeutic Ultrasound. 2015 Dec 1; 3(Suppl 1):p5. Han HM, Scott SS, Ozhinsky OE, Salgaonkar SV, Jones JP, Larson LP, Diederich DC, Krug KR, Rieke RV. .
      View in: Publisher Site   Mentions:
    21. Quantifying temperature-dependent T1 changes in cortical bone using ultrashort echo-time MRI. Magn Reson Med. 2015 Dec; 74(6):1548-55. Han M, Rieke V, Scott SJ, Ozhinsky E, Salgaonkar VA, Jones PD, Larson PE, Diederich CJ, Krug R. PMID: 26390357.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    22. Metal artifact suppression at the hip: diagnostic performance at 3.0 T versus 1.5 Tesla. Skeletal Radiol. 2015 Nov; 44(11):1609-16. Nardo L, Han M, Kretzschmar M, Kretschmar M, Guindani M, Koch K, Vail T, Krug R, Link TM. PMID: 26201676.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Variable flip angle three-dimensional fast spin-echo sequence combined with outer volume suppression for imaging trabecular bone structure of the proximal femur. Journal of Magnetic Resonance Imaging. 2015 May 1; 41(5):spcone-spcone. Han HM, Chiba CK, Banerjee BS, Carballido-Gamio CJ, Krug KR. .
      View in: Publisher Site   Mentions:
    24. Metal artefact suppression at 3 T MRI: comparison of MAVRIC-SL with conventional fast spin echo sequences in patients with Hip joint arthroplasty. Eur Radiol. 2015 Aug; 25(8):2403-11. Kretzschmar M, Nardo L, Han MM, Heilmeier U, Sam C, Joseph GB, Koch KM, Krug R, Link TM. PMID: 25680728.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    25. Validation of bone marrow fat quantification in the presence of trabecular bone using MRI. J Magn Reson Imaging. 2015 Aug; 42(2):539-44. Gee CS, Nguyen JT, Marquez CJ, Heunis J, Lai A, Wyatt C, Han M, Kazakia G, Burghardt AJ, Karampinos DC, Carballido-Gamio J, Krug R. PMID: 25425074.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    26. Cartilaginous end plates: Quantitative MR imaging with very short echo times-orientation dependence and correlation with biochemical composition. Radiology. 2015 Feb; 274(2):482-9. Fields AJ, Han M, Krug R, Lotz JC. PMID: 25302832.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    27. Variable flip angle three-dimensional fast spin-echo sequence combined with outer volume suppression for imaging trabecular bone structure of the proximal femur. J Magn Reson Imaging. 2015 May; 41(5):1300-10. Han M, Chiba K, Banerjee S, Carballido-Gamio J, Krug R. PMID: 24956149.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    28. In vitro assessment of knee MRI in the presence of metal implants comparing MAVRIC-SL and conventional fast spin echo sequences at 1.5 and 3 T field strength. J Magn Reson Imaging. 2015 May; 41(5):1291-9. Liebl H, Heilmeier U, Lee S, Nardo L, Patsch J, Schuppert C, Han M, Rondak IC, Banerjee S, Koch K, Link TM, Krug R. PMID: 24912802.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    29. Depiction of achilles tendon microstructure in vivo using high-resolution 3-dimensional ultrashort echo-time magnetic resonance imaging at 7 T. Invest Radiol. 2014 May; 49(5):339-45. Han M, Larson PE, Liu J, Krug R. PMID: 24500089.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    30. Approaches for modelling interstitial ultrasound ablation of tumours within or adjacent to bone: theoretical and experimental evaluations. Int J Hyperthermia. 2013 Nov; 29(7):629-42. Scott SJ, Prakash P, Salgaonkar V, Jones PD, Cam RN, Han M, Rieke V, Burdette EC, Diederich CJ. PMID: 24102393.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    31. Homogenous fat suppression for bilateral breast imaging using independent shims. Magn Reson Med. 2014 Apr; 71(4):1511-7. Han M, Cunningham CH, Pauly JM, Daniel BL, Hargreaves BA. PMID: 23821305.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    32. Reduction of flow artifacts by using partial saturation in RF-spoiled gradient-echo imaging. Magn Reson Med. 2011 May; 65(5):1326-34. Han M, Hargreaves BA. PMID: 21319219.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    33. Independent slab-phase modulation combined with parallel imaging in bilateral breast MRI. Magn Reson Med. 2009 Nov; 62(5):1221-31. Han M, Beatty PJ, Daniel BL, Hargreaves BA. PMID: 19780156.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    34. Accelerated bilateral dynamic contrast-enhanced 3D spiral breast MRI using TSENSE. J Magn Reson Imaging. 2008 Dec; 28(6):1425-34. Han M, Daniel BL, Hargreaves BA. PMID: 19025951.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
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