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TIP60 is required for tumorigenesis in non-small cell lung cancer. Cancer Sci. 2023 Mar 14.
Shibahara D, Akanuma N, Kobayashi IS, Heo E, Ando M, Fujii M, Jiang F, Prin PN, Pan G, Wong KK, Costa DB, Bararia D, Tenen DG, Watanabe H, Kobayashi SS. PMID: 36916958.
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Fundic Gland Polyps Lack DNA Content Abnormality Characteristic of Other Adenomatous Precursor Lesions in the Gastrointestinal Tract. Mod Pathol. 2023 Feb 01; 36(5):100117.
Akanuma N, Rabinovitch PS, Mattis AN, Lauwers GY, Choi WT. PMID: 36805791.
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Humans
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Paracrine Secretion of Transforming Growth Factor β by Ductal Cells Promotes Acinar-to-Ductal Metaplasia in Cultured Human Exocrine Pancreas Tissues. Pancreas. 2017 10; 46(9):1202-1207.
Akanuma N, Liu J, Liou GY, Yin X, Bejar KR, Liu C, Sun LZ, Storz P, Wang P. PMID: 28902792; PMCID: PMC6192250.
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4 Fields:
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HumansAnimalsCells
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Fra-1 Regulates the Expression of HMGA1, Which is Associated with a Poor Prognosis in Human Esophageal Squamous Cell Carcinoma. Ann Surg Oncol. 2017 Oct; 24(11):3446-3455.
Toyozumi T, Hoshino I, Takahashi M, Usui A, Akutsu Y, Hanari N, Murakami K, Kano M, Akanuma N, Suitoh H, Matsumoto Y, Sekino N, Komatsu A, Matsubara H. PMID: 27882471.
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6 Fields:
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HumansCells
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TGF-β1 promotes acinar to ductal metaplasia of human pancreatic acinar cells. Sci Rep. 2016 08 03; 6:30904.
Liu J, Akanuma N, Liu C, Naji A, Halff GA, Washburn WK, Sun L, Wang P. PMID: 27485764; PMCID: PMC4971483.
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20 Fields:
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HumansCells
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Treatment of near-infrared photodynamic therapy using a liposomally formulated indocyanine green derivative for squamous cell carcinoma. PLoS One. 2015; 10(4):e0122849.
Maruyama T, Akutsu Y, Suganami A, Tamura Y, Fujito H, Ouchi T, Akanuma N, Isozaki Y, Takeshita N, Hoshino I, Uesato M, Toyota T, Hayashi H, Matsubara H. PMID: 25850029; PMCID: PMC4388603.
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3 Fields:
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AnimalsCells
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Histone Demethylase LSD1 Inhibitors Prevent Cell Growth by Regulating Gene Expression in Esophageal Squamous Cell Carcinoma Cells. Ann Surg Oncol. 2016 Jan; 23(1):312-20.
Hoshino I, Akutsu Y, Murakami K, Akanuma N, Isozaki Y, Maruyama T, Toyozumi T, Matsumoto Y, Suito H, Takahashi M, Sekino N, Komatsu A, Suzuki T, Matsubara H. PMID: 25791791.
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13 Fields:
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HumansCells
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Detection of peritoneal dissemination with near-infrared fluorescence laparoscopic imaging using a liposomal formulation of a synthesized indocyanine green liposomal derivative. Anticancer Res. 2015 Mar; 35(3):1353-9.
Hoshino I, Maruyama T, Fujito H, Tamura Y, Suganami A, Hayashi H, Toyota T, Akutsu Y, Murakami K, Isozaki Y, Akanuma N, Takeshita N, Toyozumi T, Komatsu A, Matsubara H. PMID: 25750285.
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4 Fields:
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HumansAnimalsCells
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Usefulness of microRNA‑375 as a prognostic and therapeutic tool in esophageal squamous cell carcinoma. Int J Oncol. 2015 Mar; 46(3):1059-66.
Isozaki Y, Hoshino I, Akutsu Y, Hanari N, Mori M, Nishimori T, Murakami K, Akanuma N, Takeshita N, Maruyama T, Toyozumi T, Takahashi M, Suito H, Matsubara H. PMID: 25501018.
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10 Fields:
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HumansAnimals
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The outcome of laparoscopic surgery with and without short gastric vessel division for achalasia. Int Surg. 2014 Nov-Dec; 99(6):846-50.
Akutsu Y, Hanari N, Kono T, Uesato M, Hoshino I, Murakami K, Natsume T, Isozaki Y, Akanuma N, Toyozumi T, Suito H, Matsubara H. PMID: 25437598; PMCID: PMC4254251.
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Humans
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Modulated electro-hyperthermia enhances dendritic cell therapy through an abscopal effect in mice. Oncol Rep. 2014 Dec; 32(6):2373-9.
Qin W, Akutsu Y, Andocs G, Suganami A, Hu X, Yusup G, Komatsu-Akimoto A, Hoshino I, Hanari N, Mori M, Isozaki Y, Akanuma N, Tamura Y, Matsubara H. PMID: 25242303.
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21 Fields:
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HumansAnimalsCells
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Screening of alternative drugs to the tumor suppressor miR-375 in esophageal squamous cell carcinoma using the connectivity map. Oncology. 2014; 87(6):351-63.
Isozaki Y, Hoshino I, Akutsu Y, Hanari N, Mori M, Nishimori T, Murakami K, Akanuma N, Toyozumi T, Takahashi M, Suito H, Takeshita N, Maruyama T, Suzuki A, Nakayama T, Matsubara H. PMID: 25195536.
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4 Fields:
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HumansCells
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Giant esophageal gastrointestinal stromal tumor: report of a case. Surg Today. 2015 Feb; 45(2):247-52.
Nakano A, Akutsu Y, Shuto K, Uesato M, Kono T, Hoshino I, Akanuma N, Maruyama T, Isozaki Y, Matsubara H. PMID: 24890800.
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6 Fields:
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Humans
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A COX-2 inhibitor enhances the antitumor effects of chemotherapy and radiotherapy for esophageal squamous cell carcinoma. Int J Oncol. 2014 Apr; 44(4):1146-52.
Yusup G, Akutsu Y, Mutallip M, Qin W, Hu X, Komatsu-Akimoto A, Hoshino I, Hanari N, Mori M, Akanuma N, Isozaki Y, Matsubara H. PMID: 24535229.
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PubMed Mentions:
14 Fields:
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HumansCells
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Incidence, risk factors and treatment outcomes of extravasation of cytotoxic agents in an outpatient chemotherapy clinic. Jpn J Clin Oncol. 2014 Feb; 44(2):168-71.
Sakaida E, Sekine I, Iwasawa S, Kurimoto R, Uehara T, Ooka Y, Akanuma N, Tada Y, Imai C, Oku T, Takiguchi Y. PMID: 24302758.
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3 Fields:
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Humans
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The overall prevalence of metastasis in T1 esophageal squamous cell carcinoma: a retrospective analysis of 295 patients. Ann Surg. 2013 Jun; 257(6):1032-8.
Akutsu Y, Uesato M, Shuto K, Kono T, Hoshino I, Horibe D, Sazuka T, Takeshita N, Maruyama T, Isozaki Y, Akanuma N, Matsubara H. PMID: 23108117.
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PubMed Mentions:
59 Fields:
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Humans
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A phase 1/11 study of second-line chemotherapy with fractionated docetaxel and nedaplatin for 5-FU/cisplatin-resistant esophageal squamous cell carcinoma. Hepatogastroenterology. 2012 Oct; 59(119):2095-8.
Akutsu Y, Shuto K, Kono T, Uesato M, Hoshino I, Shiratori T, Miyazawa Y, Isozaki Y, Akanuma N, Matsubara H. PMID: 22328303.
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8 Fields:
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HumansCTClinical Trials
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miR-203 inhibits the migration and invasion of esophageal squamous cell carcinoma by regulating LASP1. Int J Oncol. 2012 Nov; 41(5):1653-61.
Takeshita N, Mori M, Kano M, Hoshino I, Akutsu Y, Hanari N, Yoneyama Y, Ikeda N, Isozaki Y, Maruyama T, Akanuma N, Miyazawa Y, Matsubara H. PMID: 22940702.
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PubMed Mentions:
33 Fields:
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HumansCells
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Identification of novel molecular targets regulated by tumor suppressive miR-375 induced by histone acetylation in esophageal squamous cell carcinoma. Int J Oncol. 2012 Sep; 41(3):985-94.
Isozaki Y, Hoshino I, Nohata N, Kinoshita T, Akutsu Y, Hanari N, Mori M, Yoneyama Y, Akanuma N, Takeshita N, Maruyama T, Seki N, Nishino N, Yoshida M, Matsubara H. PMID: 22752059.
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30 Fields:
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HumansCells
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Primary esophageal adenocarcinoma arising from heterotopic gastric mucosa: report of a case. Surg Today. 2013 Apr; 43(4):446-51.
Akanuma N, Hoshino I, Akutsu Y, Shuto K, Shiratori T, Kono T, Uesato M, Sato A, Isozaki Y, Maruyama T, Takeshita N, Matsubara H. PMID: 22706784.
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8 Fields:
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Humans
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The number of pathologic lymph nodes involved is still a significant prognostic factor even after neoadjuvant chemoradiotherapy in esophageal squamous cell carcinoma. J Surg Oncol. 2012 Jun 15; 105(8):756-60.
Akutsu Y, Shuto K, Kono T, Uesato M, Hoshino I, Shiratori T, Isozaki Y, Akanuma N, Uno T, Matsubara H. PMID: 22162007.
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13 Fields:
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Humans
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[The present state and task of the Palliative Care Team at Tokyo Women's Medical University Yachiyo Medical Center]. Gan To Kagaku Ryoho. 2007 Dec; 34 Suppl 2:201-2.
Imai K, Shirotani N, Hirai E, Akanuma N, Nishino T, Sato J, Kimura K, Egawa T, Shimono S. PMID: 20443260.
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Humans