Nathan Lo, MD, PhD

Title(s)Clinical Fellow, Medicine
SchoolSchool of Medicine
Address1001 Potrero Avenue
San Francisco CA 94110
Phone628-206-9854
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    Collapse Biography 
    Collapse Education and Training
    Rice UniversityBS2013Bioengineering
    Stanford UniversityPhD2019Epidemiology
    Stanford UniversityMD2019Medicine
    UCSFResidency2021Internal Medicine
    Collapse Awards and Honors
    Media coverage New York Times, CNN, BBC, The Guardian, NPR, San Francisco Chronicle, Scientific American, ABC, NBC
    Top 5 articles of 20172017JAMA Pediatrics
    Kass Award2016Infectious Diseases Society of America
    Clinical Research Mentorship (CRM) grantee2015Doris Duke Charitable Foundation
    Medical Scholar2015Infectious Diseases Society of America
    Benjamin H. Kean Fellow2015American Society of Tropical Medicine and Hygiene
    Young Investigator Award2015Conference on Retroviruses and Opportunistic Infections
    Student/Post-Doc Travel Award2014American Society of Tropical Medicine and Hygiene
    Top Graduate (Outstanding Senior) 2013 Rice University Department of Bioengineering

    Collapse Overview 
    Collapse Overview
    I am a Faculty Fellow in Infectious Diseases (Research) in the Division of HIV, Infectious Diseases, and Global Medicine at the University of California San Francisco (UCSF). My research group (http://lolab.ucsf.edu/) studies the transmission of infectious diseases with an ultimate goal of informing public health policy. My research blends diverse computational methodologies, including tools of simulation modeling, decision analysis, machine learning, and microbial genomics. My interest spans across multiple infectious diseases including neglected tropical diseases, vaccine-preventable infections, and COVID-19. My research group is affiliated with the Experimental and Population-based Pathogen Investigation center (EPPIcenter).

    A large emphasis of my work is translating scientific evidence into public health policy. Our track record includes multiple studies that have changed policy in the fields of tropical diseases, HIV, and COVID-19. I work closely with policy organizations like the World Health Organization and the California Department of Public Health. From 2018-2021, I served as the lead writer and editor for the WHO guidelines on public health control and elimination of schistosomiasis. My work has been supported by grants from the Bill and Melinda Gates Foundation, California Department of Public Health, and World Health Organization. I received a BS in Bioengineering from Rice University and MD/PhD (Epidemiology) from Stanford University. I completed my clinical residency in internal medicine at UCSF, and am a clinical fellow in infectious diseases.

    My current research focuses on the following areas:
    (1) Public health strategies to control the COVID-19 pandemic
    (2) Public health strategies for tropical infections, such as helminths infections and typhoid fever
    (3) Vaccine-preventable infectious diseases in the United States
    Collapse In The News
    Collapse Global Health Equity

    Collapse Research 
    Collapse Research Activities and Funding
    Identifying hot spots of transmission to improve equity in mass drug administration programs against schistosomiasis
    UCSF IGHS Affiliate Seed Award Jul 1, 2022
    Role: Principal investigator
    Development, evaluation, and integration of mobile phone microscopes for the rapid diagnosis of schistosomiasis in public health programs
    University Health Network Apr 12, 2022
    Role: Co-Investigator
    COVID-19 vaccination and public health control in California
    California Department of Public Health Sep 1, 2020
    Role: Principal investigator
    Evaluation of evidence from mathematical modeling studies in WHO guidelines
    World Health Organization Jul 1, 2019 - Jul 1, 2021
    Role: Co-Principal investigator
    Guidelines on public health control of schistosomiasis
    World Health Organization Jan 1, 2018 - Feb 15, 2022
    Role: Lead guidelines writer and editor

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Featured Content 
    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. COVID-19 Vaccination and Estimated Public Health Impact in California. JAMA Netw Open. 2022 Apr 01; 5(4):e228526. Tan ST, Park HJ, Rodríguez-Barraquer I, Rutherford GW, Bibbins-Domingo K, Schechter R, Lo NC. PMID: 35452106.
      View in: PubMed   Mentions:
    2. Risk factor targeting for vaccine prioritization during the COVID-19 pandemic. Sci Rep. 2022 02 23; 12(1):3055. Chapman LAC, Shukla P, Rodríguez-Barraquer I, Shete PB, León TM, Bibbins-Domingo K, Rutherford GW, Schechter R, Lo NC. PMID: 35197495; PMCID: PMC8866501.
      View in: PubMed   Mentions:
    3. Predicting covid-19 outcomes. BMJ. 2022 02 17; 376:o354. Habib AR, Lo NC. PMID: 35177413.
      View in: PubMed   Mentions:
    4. WHO guideline on control and elimination of human schistosomiasis. World Health Organization. 2022. View Publication.
    5. Geographic Pattern of Typhoid Fever in India: A Model-Based Estimate of Cohort and Surveillance Data. J Infect Dis. 2021 11 23; 224(224 Supple 5):S475-S483. Cao Y, Karthikeyan AS, Ramanujam K, Raju R, Krishna S, Kumar D, Ryckman T, Mohan VR, Kang G, John J, Andrews JR, Lo NC. PMID: 35238365; PMCID: PMC8892532.
      View in: PubMed   Mentions:
    6. Comparison of Strategies for Typhoid Conjugate Vaccine Introduction in India: A Cost-Effectiveness Modeling Study. J Infect Dis. 2021 11 23; 224(Supple 5):S612-S624. Ryckman T, Karthikeyan AS, Kumar D, Cao Y, Kang G, Goldhaber-Fiebert JD, John J, Lo NC, Andrews JR. PMID: 35238367; PMCID: PMC8892534.
      View in: PubMed   Mentions:
    7. Frequency of Routine Testing for Coronavirus Disease 2019 (COVID-19) in High-risk Healthcare Environments to Reduce Outbreaks. Clin Infect Dis. 2021 11 02; 73(9):e3127-e3129. Chin ET, Huynh BQ, Chapman LAC, Murrill M, Basu S, Lo NC. PMID: 33570097; PMCID: PMC7797732.
      View in: PubMed   Mentions: 17     Fields:    
    8. Addendum needed on COVID-19 travel study - Authors' reply. Lancet Infect Dis. 2021 11; 21(11):1495-1496. Kiang MV, Chin ET, Huynh BQ, Chapman LAC, Lo NC. PMID: 34536351; PMCID: PMC8443231.
      View in: PubMed   Mentions:    Fields:    
    9. Comparison of infection control strategies to reduce COVID-19 outbreaks in homeless shelters in the United States: a simulation study. BMC Med. 2021 05 07; 19(1):116. Chapman LAC, Kushel M, Cox SN, Scarborough A, Cawley C, Nguyen TQ, Rodriguez-Barraquer I, Greenhouse B, Imbert E, Lo NC. PMID: 33962621; PMCID: PMC8103431.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    10. Routine asymptomatic testing strategies for airline travel during the COVID-19 pandemic: a simulation study. Lancet Infect Dis. 2021 07; 21(7):929-938. Kiang MV, Chin ET, Huynh BQ, Chapman LAC, Rodríguez-Barraquer I, Greenhouse B, Rutherford GW, Bibbins-Domingo K, Havlir D, Basu S, Lo NC. PMID: 33765417; PMCID: PMC7984872.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    11. Influenza, Varicella, and Mumps Outbreaks in US Migrant Detention Centers. JAMA. 2021 Jan 12; 325(2):180-182. Lo NC, Nyathi S, Chapman LAC, Rodriguez-Barraquer I, Kushel M, Bibbins-Domingo K, Lewnard JA. PMID: 33119037; PMCID: PMC7596678.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    12. Comparison of World Health Organization and Demographic and Health Surveys data to estimate sub-national deworming coverage in pre-school aged children. PLoS Negl Trop Dis. 2020 08; 14(8):e0008551. Lo NC, Gupta R, Addiss DG, Bendavid E, Heft-Neal S, Mikhailov A, Montresor A, Mbabazi PS. PMID: 32804925; PMCID: PMC7462292.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Projected geographic disparities in healthcare worker absenteeism from COVID-19 school closures and the economic feasibility of child care subsidies: a simulation study. BMC Med. 2020 07 15; 18(1):218. Chin ET, Huynh BQ, Lo NC, Hastie T, Basu S. PMID: 32664927; PMCID: PMC7360472.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    14. Application of Schistosomiasis Consortium for Operational Research and Evaluation Study Findings to Refine Predictive Modeling of Schistosoma mansoni and Schistosoma haematobium Control in Sub-Saharan Africa. Am J Trop Med Hyg. 2020 07; 103(1_Suppl):97-104. King CH, Yoon N, Wang X, Lo NC, Alsallaq R, Ndeffo-Mbah M, Li E, Gurarie D. PMID: 32400357; PMCID: PMC7351296.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsPHPublic Health
    15. Childhood vaccines and antibiotic use in low- and middle-income countries. Nature. 2020 05; 581(7806):94-99. Lewnard JA, Lo NC, Arinaminpathy N, Frost I, Laxminarayan R. PMID: 32376956; PMCID: PMC7332418.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    16. Scientific and ethical basis for social-distancing interventions against COVID-19. Lancet Infect Dis. 2020 06; 20(6):631-633. Lewnard JA, Lo NC. PMID: 32213329; PMCID: PMC7118670.
      View in: PubMed   Mentions: 213     Fields:    Translation:CellsPHPublic Health
    17. The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis. Lancet. 2020 03 21; 395(10228):973-984. Martinez L, Cords O, Horsburgh CR, Andrews JR, Pediatric TB Contact Studies Consortium. PMID: 32199484; PMCID: PMC7289654.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsPHPublic Health
    18. Hunter's Tropical Medicine and Emerging Infectious Diseases. Neglected Tropical Diseases: Public Health Control Programs and Mass Drug Administration. 2020. .
    19. The 2016 California policy to eliminate nonmedical vaccine exemptions and changes in vaccine coverage: An empirical policy analysis. PLoS Med. 2019 12; 16(12):e1002994. Nyathi S, Karpel HC, Sainani KL, Maldonado Y, Hotez PJ, Bendavid E, Lo NC. PMID: 31869328; PMCID: PMC6927583.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    20. Improving public health control of schistosomiasis with a modified WHO strategy: a model-based comparison study. Lancet Glob Health. 2019 10; 7(10):e1414-e1422. Li EY, Gurarie D, Lo NC, Zhu X, King CH. PMID: 31537371; PMCID: PMC7024988.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansPHPublic Health
    21. State of deworming coverage and equity in low-income and middle-income countries using household health surveys: a spatiotemporal cross-sectional study. Lancet Glob Health. 2019 11; 7(11):e1511-e1520. Lo NC, Heft-Neal S, Coulibaly JT, Leonard L, Bendavid E, Addiss DG. PMID: 31558383; PMCID: PMC7024997.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    22. Clinical evaluation for morbidity associated with soil-transmitted helminth infection in school-age children on Pemba Island, Tanzania. PLoS Negl Trop Dis. 2019 07; 13(7):e0007581. Bogoch II, Speich B, Lo NC, Moser W, Croll D, Ali SM, Ame SM, Utzinger J, Andrews JR, Keiser J. PMID: 31306433; PMCID: PMC6658009.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    23. Antibacterial mass drug administration for child mortality reduction: Opportunities, concerns, and possible next steps. PLoS Negl Trop Dis. 2019 05; 13(5):e0007315. Bogoch II, Utzinger J, Lo NC, Andrews JR. PMID: 31120903; PMCID: PMC6532835.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    24. Paediatric tuberculosis transmission outside the household: challenging historical paradigms to inform future public health strategies. Lancet Respir Med. 2019 06; 7(6):544-552. Martinez L, Lo NC, Cords O, Hill PC, Khan P, Hatherill M, Mandalakas A, Kay A, Croda J, Horsburgh CR, Zar HJ, Andrews JR. PMID: 31078497; PMCID: PMC7323920.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCellsPHPublic Health
    25. Comparison of Strategies and Incidence Thresholds for Vi Conjugate Vaccines Against Typhoid Fever: A Cost-effectiveness Modeling Study. J Infect Dis. 2018 11 10; 218(suppl_4):S232-S242. Lo NC, Gupta R, Stanaway JD, Garrett DO, Bogoch II, Luby SP, Andrews JR. PMID: 29444257; PMCID: PMC6226717.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansPHPublic Health
    26. Modulation of Antibody Responses to the V1V2 and V3 Regions of HIV-1 Envelope by Immune Complex Vaccines. Front Immunol. 2018; 9:2441. Hioe CE, Kumar R, Upadhyay C, Jan M, Fox A, Itri V, Peachman KK, Rao M, Liu L, Lo NC, Tuen M, Jiang X, Kong XP, Zolla-Pazner S. PMID: 30416503; PMCID: PMC6212562.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    27. Typhoid conjugate vaccines: a new tool in the fight against antimicrobial resistance. Lancet Infect Dis. 2019 01; 19(1):e26-e30. Andrews JR, Baker S, Marks F, Alsan M, Garrett D, Gellin BG, Saha SK, Qamar FN, Yousafzai MT, Bogoch II, Antillon M, Pitzer VE, Kim JH, John J, Gauld J, Mogasale V, Ryan ET, Luby SP, Lo NC. PMID: 30170987.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCellsPHPublic Health
    28. Deworming in pre-school age children: A global empirical analysis of health outcomes. PLoS Negl Trop Dis. 2018 05; 12(5):e0006500. Lo NC, Snyder J, Addiss DG, Heft-Neal S, Andrews JR, Bendavid E. PMID: 29852012; PMCID: PMC5997348.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    29. The human-snail transmission environment shapes long term schistosomiasis control outcomes: Implications for improving the accuracy of predictive modeling. PLoS Negl Trop Dis. 2018 05; 12(5):e0006514. Gurarie D, Lo NC, Ndeffo-Mbah ML, Durham DP, King CH. PMID: 29782500; PMCID: PMC5983867.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    30. Review of the 2017 WHO Guideline: Preventive chemotherapy to control soil-transmitted helminth infections in at-risk population groups. An opportunity lost in translation. PLoS Negl Trop Dis. 2018 04; 12(4):e0006296. Savioli L, Albonico M, Daumerie D, Lo NC, Stothard JR, Asaolu S, Tchuem Tchuenté LA, Anderson RM. PMID: 29698486; PMCID: PMC5919405.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsPHPublic Health
    31. Invasive Pomacea snails as important intermediate hosts of Angiostrongylus cantonensis in Laos, Cambodia and Vietnam: Implications for outbreaks of eosinophilic meningitis. Acta Trop. 2018 Jul; 183:32-35. Lv S, Guo YH, Nguyen HM, Sinuon M, Sayasone S, Lo NC, Zhou XN, Andrews JR. PMID: 29574000.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsPHPublic Health
    32. Impact and cost-effectiveness of snail control to achieve disease control targets for schistosomiasis. Proc Natl Acad Sci U S A. 2018 01 23; 115(4):E584-E591. Lo NC, Gurarie D, Yoon N, Coulibaly JT, Bendavid E, Andrews JR, King CH. PMID: 29301964; PMCID: PMC5789907.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimals
    33. Schistosoma haematobium Egg Excretion does not Increase after Exercise: Implications for Diagnostic Testing. Am J Trop Med Hyg. 2018 03; 98(3):772-775. Coulibaly JT, Andrews JR, Lo NC, N'Goran EK, Utzinger J, Keiser J, Bogoch II. PMID: 29260647; PMCID: PMC5930907.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    34. Public Health and Economic Consequences of Vaccine Hesitancy for Measles in the United States. JAMA Pediatr. 2017 09 01; 171(9):887-892. Lo NC, Hotez PJ. PMID: 28738137; PMCID: PMC5710408.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansPHPublic Health
    35. Mobile phone and handheld microscopes for public health applications. Lancet Public Health. 2017 08; 2(8):e355. Bogoch II, Lundin J, Lo NC, Andrews JR. PMID: 29253476.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    36. Mobile-phone and handheld microscopy for neglected tropical diseases. PLoS Negl Trop Dis. 2017 07; 11(7):e0005550. Rajchgot J, Coulibaly JT, Keiser J, Utzinger J, Lo NC, Mondry MK, Andrews JR, Bogoch II. PMID: 28683127; PMCID: PMC5499985.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    37. The Perils of Trumping Science in Global Health - The Mexico City Policy and Beyond. N Engl J Med. 2017 Apr 13; 376(15):1399-1401. Lo NC, Barry M. PMID: 28225666.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    38. A call to strengthen the global strategy against schistosomiasis and soil-transmitted helminthiasis: the time is now. Lancet Infect Dis. 2017 02; 17(2):e64-e69. Lo NC, Addiss DG, Hotez PJ, King CH, Stothard JR, Evans DS, Colley DG, Lin W, Coulibaly JT, Bustinduy AL, Raso G, Bendavid E, Bogoch II, Fenwick A, Savioli L, Molyneux D, Utzinger J, Andrews JR. PMID: 27914852; PMCID: PMC5280090.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    39. Comparison of sensitivity and faecal egg counts of Mini-FLOTAC using fixed stool samples and Kato-Katz technique for the diagnosis of Schistosoma mansoni and soil-transmitted helminths. Acta Trop. 2016 Dec; 164:107-116. Coulibaly JT, Ouattara M, Becker SL, Lo NC, Keiser J, N'Goran EK, Ianniello D, Rinaldi L, Cringoli G, Utzinger J. PMID: 27591137.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    40. Evaluation of a Urine Pooling Strategy for the Rapid and Cost-Efficient Prevalence Classification of Schistosomiasis. PLoS Negl Trop Dis. 2016 08; 10(8):e0004894. Lo NC, Coulibaly JT, Bendavid E, N'Goran EK, Utzinger J, Keiser J, Bogoch II, Andrews JR. PMID: 27504954; PMCID: PMC4978437.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    41. Improving helminth treatment access: costs and opportunities. Lancet Infect Dis. 2016 07; 16(7):762-764. Lo NC, Andrews JR, Bogoch II. PMID: 27352742.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    42. Assessment of global guidelines for preventive chemotherapy against schistosomiasis and soil-transmitted helminthiasis: a cost-effectiveness modelling study. Lancet Infect Dis. 2016 Sep; 16(9):1065-1075. Lo NC, Lai YS, Karagiannis-Voules DA, Bogoch II, Coulibaly JT, Bendavid E, Utzinger J, Vounatsou P, Andrews JR. PMID: 27286968.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    43. Abstinence Funding Was Not Associated With Reductions In HIV Risk Behavior In Sub-Saharan Africa. Health Aff (Millwood). 2016 05 01; 35(5):856-63. Lo NC, Lowe A, Bendavid E. PMID: 27140992.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    44. Cost-effectiveness of community-wide treatment for helminthiasis--Authors' reply. Lancet Glob Health. 2016 Mar; 4(3):e157-8. Lo NC, Bogoch II, Utzinger J, Andrews JR. PMID: 26848087.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    45. Comparison of community-wide, integrated mass drug administration strategies for schistosomiasis and soil-transmitted helminthiasis: a cost-effectiveness modelling study. Lancet Glob Health. 2015 Oct; 3(10):e629-38. Lo NC, Bogoch II, Blackburn BG, Raso G, N'Goran EK, Coulibaly JT, Becker SL, Abrams HB, Utzinger J, Andrews JR. PMID: 26385302.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    46. Strategies for last mile implementation of global health technologies. Lancet Glob Health. 2014 Sep; 2(9):e497-e498. Chao TE, Lo NC, Mody GN, Sinha SR. PMID: 25304406.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    47. Interaction of Shiga toxin with the A-domains and multimers of von Willebrand Factor. J Biol Chem. 2013 Nov 15; 288(46):33118-23. Lo NC, Turner NA, Cruz MA, Moake J. PMID: 24097977; PMCID: PMC3829160.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsCTClinical Trials
    48. The aging of biomedical research in the United States. PLoS One. 2011; 6(12):e29738. Matthews KR, Calhoun KM, Lo N, Ho V. PMID: 22216352; PMCID: PMC3247288.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
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