Nevan Krogan, PhD

Title(s)Professor, Bioengineering
SchoolSchool of Pharmacy
Address1700 4th Street, #308-D
San Francisco CA 94158
Phone415-476-2980
PronounsHe/Him/His
ORCID ORCID Icon0000-0003-4902-337X Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Regina, Regina, Saskatchewan, CanadaBSc (Hons)05/1997Biochemistry
    University of Regina, Regina, Saskatchewan, CanadaMSc08/1999Biology
    University of Toronto, Toronto, Ontario, CanadaPhD06/2006Medical Genetics
    Collapse Awards and Honors
    European Molecular Biology Organization2022Elected to EMBO
    President of the French Republic2021France Legion of Honor
    Laboratory of Genomics Research2020Excellence in Research Award
    Clarivate Web of Science2020Highly Cited Researchers 2020 - ranked in top 1% of citations for field and year
    Roddenberry Foundation2017The Roddenberry Prize
    Blavatnik Foundation2015  - 2016Blavatnik Scholar
    Cell 2014Top 40 Under 40
    University of Regina2012Distinguished Alumni Award
    W. M. Keck Foundation2009  - 2014Keck Distinguished Young Scholar
    Searle Foundation2009  - 2012Searle Scholar
    Sciencewatch.com2008Top 25 authors of high-impact papers in molecular biology and genetics from 2002 to 2006
    University of Toronto2005L. W. Macpherson Microbiology Award
    University of Toronto2004Hannah Farkas-Himsley and Alexander Memorial Award
    Canadian Institute of Health Research2001  - 2004CIHR Doctoral Fellowship
    Natural Sciences and Engineering Research Council 1999  - 2001PGS-B Award
    Society of Chemical Industry 1997Merit Award
    Canadian Cancer Society 1995  - 1996Studentship

    Collapse Overview 
    Collapse Overview
    Dr. Krogan was born and raised in Regina, Saskatchewan, Canada, obtained his undergraduate degree from the University of Regina and his PhD from the University of Toronto. Dr. Krogan’s lab at UCSF focuses on developing and applying quantitative, systematic proteomic and genetic approaches to study complex biological and biomedical problems. At present time, the Krogan group is focused on studying cancer, infectious disease and psychiatric disorders.
    Collapse In The News
    Collapse Global Health Equity

    Collapse Research 
    Collapse Research Activities and Funding
    The Cancer Cell Map Initiative v2.0
    NIH 1U54CA274502Sep 15, 2022 - Aug 31, 2027
    Role: Co-Principal Investigator
    Building an Interpretable Genomic Translator Using Maps of Cell Architecture
    NIH OT2OD032742Sep 1, 2022 - Aug 31, 2025
    Role: Co-Principal Investigator
    HARC: HIV accessory and regulatory complexes
    NIH U54AI170792Jul 15, 2022 - Apr 30, 2027
    Role: Principal Investigator
    QCRG Pandemic Response Program
    NIH U19AI171110May 16, 2022 - Apr 30, 2025
    Role: Principal Investigator
    Host Pathogen Variation & TB Pathogenesis
    NIH U19AI162583Aug 1, 2021 - May 31, 2026
    Role: Co-Investigator
    Childhood ?Omics? and Mycobacterium tuberculosis-derived BiOsignatures (COMBO) for TB diagnosis in high HIV prevalence settings
    NIH R01AI152161Apr 22, 2020 - Mar 31, 2025
    Role: Co-Investigator
    Proteomic and Genetic Approaches Defining Apolipoprotein E4 Neuropathologic Mechanisms
    NIH RF1AG059751Sep 15, 2019 - Mar 31, 2024
    Role: Co-Principal Investigator
    Combinatorial Regulation of Gene Networks During Cardiac Development and Disease
    NIH P01HL146366Sep 1, 2019 - Aug 31, 2024
    Role: Co-Investigator
    Novel VP30-host Interactions that Negatively Regulate Ebola Virus Infection
    NIH R01AI143292Mar 1, 2019 - Feb 29, 2024
    Role: Co-Principal Investigator
    CasCUT&RUN: An in vivo method to analyze locus-specific protein complexes driving transcription of target genes in cancer
    NIH R21CA235303Feb 15, 2019 - Jan 31, 2022
    Role: Co-Principal Investigator
    The Psychiatric Cell Map Initiative: Connecting Genomics, Subcellular Networks, and Higher Order Phenotypes
    NIH U01MH115747Sep 5, 2018 - Jun 30, 2023
    Role: Co-Principal Investigator
    HPMI: Host Pathogen Mapping Initiative
    NIH U19AI135990Aug 17, 2018 - Jul 31, 2022
    Role: Co-Principal Investigator
    Fluomics: The Next Generation
    NIH U19AI135972Jan 20, 2018 - Dec 31, 2022
    Role: Co-Investigator
    Research Center for Cancer Systems Biology: Cancer Cell Map Initiative
    NIH U54CA209891May 11, 2017 - Apr 30, 2022
    Role: Co-Principal Investigator
    Linking tau proteostasis with neuronal activity in FTD
    NIH U54NS100717Sep 30, 2016 - Aug 31, 2021
    Role: Co-Investigator
    Proteomics Analysis of Host-Pathogen Interactions in Histoplasma
    NIH R21AI122064Dec 15, 2015 - Nov 30, 2017
    Role: Co-Principal Investigator
    Decoding the Chlamydia inclusion membrane protein-host protein interactome
    NIH R01AI122747Dec 1, 2015 - Nov 30, 2020
    Role: Co-Principal Investigator
    Discovery of novel, ubiquitin-regulated mechanisms of TB control by macrophages
    NIH R01AI120694Aug 1, 2015 - Jan 31, 2021
    Role: Principal Investigator
    Dengue Human Immunology Project Consortium (DHIPC)
    NIH U19AI118610Jun 24, 2015 - May 31, 2020
    Role: Co-Investigator
    Physical and Genetic Interaction Landscape of the Tyrosine Kinome
    NIH R01GM107671Sep 1, 2014 - Jun 30, 2019
    Role: Co-Principal Investigator
    Multiscale analysis of influenza host-pathogen interactions: Fluomics
    NIH U19AI106754Jun 26, 2013 - May 31, 2018
    Role: Co-Investigator
    Integrating computation and genetics to quantify specificity in protein networks
    NIH R01GM098101Aug 1, 2011 - May 31, 2016
    Role: Principal Investigator
    Protein homeostasis mechanisms underlying enterovirus replication and evolution
    NIH P01AI091575Jul 13, 2011 - Jun 30, 2016
    Role: Co-Investigator
    Exploring Design Principles of Cellular Control Circuits
    NIH P50GM081879Sep 1, 2010 - Jul 31, 2019
    Role: Co-Investigator
    Global innate immune responses to HIV-1 infection
    NIH P01AI090935Aug 15, 2010 - Jul 31, 2015
    Role: Co-Investigator
    Global Genetic Interaction Profiling in Prokaryotes
    NIH R01GM085697Sep 25, 2008 - Jul 31, 2012
    Role: Co-Principal Investigator
    Comparative Analysis of Genetic Interaction Networks
    NIH R01GM084279Aug 1, 2008 - Feb 28, 2019
    Role: Co-Principal Investigator
    Genetic Analysis of the Nucleosome and RNA Polymerase II: A Systems Approach
    NIH R01GM084448Jun 1, 2008 - Apr 30, 2014
    Role: Principal Investigator
    HARC Center: HIV Accessory and Regulatory Complexes
    NIH P50AI150476Aug 27, 2007 - Aug 31, 2022
    Role: Principal Investigator
    HARC Center: HIV Accessory and Regulatory Complexes
    NIH P50GM082250Aug 27, 2007 - Aug 31, 2022
    Role: Principal Investigator
    Transcriptional Networks During Cardiac Differentiation
    NIH P01HL089707Jul 1, 2007 - Jul 31, 2018
    Role: Co-Investigator
    Intracellular pathogens and innate immunity
    NIH P01AI063302Sep 30, 2004 - Jun 30, 2021
    Role: Co-Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator

    Collapse ORNG Applications 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Central control of dynamic gene circuits governs T cell rest and activation. Nature. 2024 Dec 11. Arce MM, Umhoefer JM, Arang N, Kasinathan S, Freimer JW, Steinhart Z, Shen H, Pham MTN, Ota M, Wadhera A, Dajani R, Dorovskyi D, Chen YY, Liu Q, Zhou Y, Swaney DL, Obernier K, Shy BR, Carnevale J, Satpathy AT, Krogan NJ, Pritchard JK, Marson A. PMID: 39663454.
      View in: PubMed   Mentions:    Fields:    
    2. HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma. Cancer Res. 2024 Dec 09. Turnham RE, Pitea A, Jang GM, Xu Z, Lim HC, Choi AL, Von Dollen J, Levin RS, Webber JT, McCarthy E, Hu J, Li X, Che L, Singh A, Yoon A, Chan G, Kelley RK, Swaney DL, Zhang W, Bandyopadhyay S, Theis FJ, Eckhardt M, Chen X, Shokat KM, Ideker T, Krogan NJ, Gordan JD. PMID: 39652575.
      View in: PubMed   Mentions:    Fields:    
    3. A Genome-Wide Screen Identifies the Evolutionarily Conserved KEOPS Complex as a Telomere Regulator. Cell. 2024 Dec 1; 187(26):7655. Downey DM, Houlsworth HR, Maringele ML, Rollie RA, Brehme BM, Galicia GS, Guillard GS, Partington PM, Zubko ZM, Krogan KN, Emili EA, Greenblatt GJ, Harrington HL, Lydall LD, Durocher DD. .
      View in: Publisher Site   Mentions:
    4. SARS-CoV-2 evolution balances conflicting roles of N protein phosphorylation. PLoS Pathog. 2024 Nov 21; 20(11):e1012741. Syed AM, Ciling A, Chen IP, Carlson CR, Adly AN, Martin HS, Taha TY, Khalid MM, Price N, Bouhaddou M, Ummadi MR, Moen JM, Krogan NJ, Morgan DO, Ott M, Doudna JA. PMID: 39571001.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. Discovery and significance of protein-protein interactions in health and disease. Cell. 2024 Nov 14; 187(23):6501-6517. Greenblatt JF, Alberts BM, Krogan NJ. PMID: 39547210.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    6. A Perturbation Cell Atlas of Human Induced Pluripotent Stem Cells. bioRxiv. 2024 Nov 04. Nourreddine S, Doctor Y, Dailamy A, Forget A, Lee YH, Chinn B, Khaliq H, Polacco B, Muralidharan M, Pan E, Zhang Y, Sigaeva A, Hansen JN, Gao J, Parker JA, Obernier K, Clark T, Chen JY, Metallo C, Lundberg E, Ideker T, Krogan N, Mali P. PMID: 39574586; PMCID: PMC11580897.
      View in: PubMed   Mentions:
    7. Protocol for mapping differential protein-protein interaction networks using affinity purification-mass spectrometry. STAR Protoc. 2024 Dec 20; 5(4):103286. Kaushal P, Ummadi MR, Jang GM, Delgado Y, Makanani SK, Alba K, Winters DM, Blanc SF, Xu J, Polacco B, Zhou Y, Stevenson E, Eckhardt M, Zuliani-Alvarez L, Kaake R, Swaney DL, Krogan NJ, Bouhaddou M. PMID: 39488835; PMCID: PMC11567037.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. Institutional Conversion to Energy-Efficient Ultra-Low Freezers Decreases Carbon Footprint and Reduces Energy Costs. Biopreserv Biobank. 2024 Sep 25. Shehu D, Kim MO, Rosendo J, Krogan N, Morgan DO, Guglielmo BJ. PMID: 39321093.
      View in: PubMed   Mentions:    Fields:    
    9. EGFR and EGFRvIII coopt host defense pathways, promoting progression in glioblastoma. Neuro Oncol. 2024 Sep 09. An Z, Fan QW, Wang L, Yoda H, Barata MJ, Jimenez-Morales D, Phillips JJ, Swaney DL, Stevenson E, Lee E, Krogan N, Weiss WA. PMID: 39248287.
      View in: PubMed   Mentions: 1     Fields:    
    10. MerlinS13 phosphorylation regulates meningioma Wnt signaling and magnetic resonance imaging features. Nat Commun. 2024 Sep 09; 15(1):7873. Eaton CD, Avalos L, Liu SJ, Chen Z, Zakimi N, Casey-Clyde T, Bisignano P, Lucas CG, Stevenson E, Choudhury A, Vasudevan HN, Magill ST, Young JS, Krogan NJ, Villanueva-Meyer JE, Swaney DL, Raleigh DR. PMID: 39251601; PMCID: PMC11383945.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    11. The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2. bioRxiv. 2024 Aug 29. Suryawanshi RK, Jaishankar P, Correy GJ, Rachman MM, O'Leary PC, Taha TY, Zapatero-Belinchón FJ, McCavittMalvido M, Doruk YU, Stevens MGV, Diolaiti ME, Jogalekar MP, Richards AL, Montano M, Rosecrans J, Matthay M, Togo T, Gonciarz RL, Gopalkrishnan S, Neitz RJ, Krogan NJ, Swaney DL, Shoichet BK, Ott M, Renslo AR, Ashworth A, Fraser JS. PMID: 39149230; PMCID: PMC11326214.
      View in: PubMed   Mentions:
    12. Fibrin drives thromboinflammation and neuropathology in COVID-19. Nature. 2024 Sep; 633(8031):905-913. Ryu JK, Yan Z, Montano M, Sozmen EG, Dixit K, Suryawanshi RK, Matsui Y, Helmy E, Kaushal P, Makanani SK, Deerinck TJ, Meyer-Franke A, Rios Coronado PE, Trevino TN, Shin MG, Tognatta R, Liu Y, Schuck R, Le L, Miyajima H, Mendiola AS, Arun N, Guo B, Taha TY, Agrawal A, MacDonald E, Aries O, Yan A, Weaver O, Petersen MA, Meza Acevedo R, Alzamora MDPS, Thomas R, Traglia M, Kouznetsova VL, Tsigelny IF, Pico AR, Red-Horse K, Ellisman MH, Krogan NJ, Bouhaddou M, Ott M, Greene WC, Akassoglou K. PMID: 39198643; PMCID: PMC11424477.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    13. Interactome of the HIV-1 proteome and human host RNA. EMBO Rep. 2024 Sep; 25(9):4078-4090. Schynkel T, Snippenberg WV, Verniers K, Jang GM, Krogan NJ, Mestdagh P, Vandekerckhove L, Trypsteen W. PMID: 39122863; PMCID: PMC11387401.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    14. Parallel genetic screens identify nuclear envelope homeostasis as a key determinant of telomere entanglement resolution in fission yeast. G3 (Bethesda). 2024 Jul 08; 14(7). Nageshan RK, Krogan N, Cooper JP. PMID: 38657142; PMCID: PMC11228871.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    15. A proximity proteomics pipeline with improved reproducibility and throughput. Mol Syst Biol. 2024 Aug; 20(8):952-971. Zhong X, Li Q, Polacco BJ, Patil T, Marley A, Foussard H, Khare P, Vartak R, Xu J, DiBerto JF, Roth BL, Eckhardt M, von Zastrow M, Krogan NJ, Hüttenhain R. PMID: 38951684; PMCID: PMC11297269.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    16. Fate of telomere entanglements is dictated by the timing of anaphase midregion nuclear envelope breakdown. Nat Commun. 2024 Jun 03; 15(1):4707. Nageshan RK, Ortega R, Krogan N, Cooper JP. PMID: 38830842; PMCID: PMC11148042.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    17. Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule. Nat Cancer. 2024 Jul; 5(7):1082-1101. Kelly LM, Rutter JC, Lin KH, Ling F, Duchmann M, Latour E, Arang N, Pasquer H, Ho Nhat D, Charles J, Killarney ST, Ang HX, Namor F, Culeux C, Lombard B, Loew D, Swaney DL, Krogan NJ, Brunel L, Carretero É, Verdié P, Amblard M, Fodil S, Huynh T, Sebert M, Adès L, Raffoux E, Fenouille N, Itzykson R, Lobry C, Benajiba L, Forget A, Martin AR, Wood KC, Puissant A. PMID: 38816660.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    18. The Chlamydia trachomatis Inc Tri1 interacts with TRAF7 to displace native TRAF7 interacting partners. Microbiol Spectr. 2024 Jul 02; 12(7):e0045324. Herrera CM, McMahon E, Swaney DL, Sherry J, Pha K, Adams-Boone K, Johnson JR, Krogan NJ, Stevers M, Solomon D, Elwell C, Engel J. PMID: 38814079; PMCID: PMC11218536.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    19. Predicted mechanistic impacts of human protein missense variants. bioRxiv. 2024 May 29. Jänes J, Müller M, Selvaraj S, Manoel D, Stephenson J, Gonçalves C, Lafita A, Polacco B, Obernier K, Alasoo K, Lemos MC, Krogan N, Martin M, Saraiva LR, Burke D, Beltrao P. PMID: 38854010; PMCID: PMC11160786.
      View in: PubMed   Mentions:
    20. Cell Maps for Artificial Intelligence: AI-Ready Maps of Human Cell Architecture from Disease-Relevant Cell Lines. bioRxiv. 2024 May 24. Clark T, Mohan J, Schaffer L, Obernier K, Al Manir S, Churas CP, Dailamy A, Doctor Y, Forget A, Hansen JN, Hu M, Lenkiewicz J, Levinson MA, Marquez C, Nourreddine S, Niestroy J, Pratt D, Qian G, Thaker S, Bélisle-Pipon JC, Brandt C, Chen J, Ding Y, Fodeh S, Krogan N, Lundberg E, Mali P, Payne-Foster P, Ratcliffe S, Ravitsky V, Sali A, Schulz W, Ideker T. PMID: 38826258; PMCID: PMC11142054.
      View in: PubMed   Mentions:
    21. Mapping Differential Protein-Protein Interaction Networks using Affinity Purification Mass Spectrometry. ArXiv. 2024 May 15. Kaushal P, Ummadi MR, Jang GM, Delgado Y, Makanani SK, Blanc SF, Winters DM, Xu J, Polacco B, Zhou Y, Stevenson E, Eckhardt M, Zuliani-Alvarez L, Kaake R, Swaney DL, Krogan N, Bouhaddou M. PMID: 38800652; PMCID: PMC11118664.
      View in: PubMed   Mentions:
    22. A proximity proteomics pipeline with improved reproducibility and throughput. bioRxiv. 2024 Apr 27. Zhong X, Li Q, Polacco BJ, Patil T, Marley A, Foussard H, Khare P, Vartak R, Xu J, DiBerto JF, Roth BL, Eckhardt M, Zastrow MV, Krogan NJ, Hüttenhain R. PMID: 37090610; PMCID: PMC10120663.
      View in: PubMed   Mentions:
    23. Global mapping of the Chlamydia trachomatis conventional secreted effector - host interactome reveals CebN interacts with nucleoporins and Rae1 to impede STAT1 nuclear translocation. bioRxiv. 2024 Apr 25. Steiert B, Andersen SE, McCaslin PN, Elwell CA, Faris R, Tijerina X, Smith P, Eldridge Q, Imai BS, Arrington JV, Yau PM, Mirrashidi KM, Johnson JR, Verschueren E, Von Dollen J, Jang GM, Krogan NJ, Engel JN, Weber MM. PMID: 38712050; PMCID: PMC11071493.
      View in: PubMed   Mentions:
    24. ATG7(2) Interacts With Metabolic Proteins and Regulates Central Energy Metabolism. Traffic. 2024 Apr; 25(4):e12933. Ostacolo K, López García de Lomana A, Larat C, Hjaltalin V, Holm KY, Hlynsdóttir SS, Soucheray M, Sooman L, Rolfsson O, Krogan NJ, Steingrimsson E, Swaney DL, Ogmundsdottir MH. PMID: 38600522; PMCID: PMC11480896.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    25. Protein Interaction Map of APOBEC3 Enzyme Family Reveals Deamination-Independent Role in Cellular Function. Mol Cell Proteomics. 2024 May; 23(5):100755. Jang GM, Annan Sudarsan AK, Shayeganmehr A, Prando Munhoz E, Lao R, Gaba A, Granadillo Rodríguez M, Love RP, Polacco BJ, Zhou Y, Krogan NJ, Kaake RM, Chelico L. PMID: 38548018; PMCID: PMC11070599.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    26. Profiling the proximal proteome of the activated μ-opioid receptor. Nat Chem Biol. 2024 Sep; 20(9):1133-1143. Polacco BJ, Lobingier BT, Blythe EE, Abreu N, Khare P, Howard MK, Gonzalez-Hernandez AJ, Xu J, Li Q, Novy B, Naing ZZC, Shoichet BK, Coyote-Maestas W, Levitz J, Krogan NJ, Von Zastrow M, Hüttenhain R. PMID: 38528119; PMCID: PMC11365811.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    27. CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. mBio. 2024 Apr 10; 15(4):e0222223. Rathore U, Haas P, Easwar Kumar V, Hiatt J, Haas KM, Bouhaddou M, Swaney DL, Stevenson E, Zuliani-Alvarez L, McGregor MJ, Turner-Groth A, Ochieng' Olwal C, Bediako Y, Braberg H, Soucheray M, Ott M, Eckhardt M, Hultquist JF, Marson A, Kaake RM, Krogan NJ. PMID: 38411080; PMCID: PMC11005436.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    28. Spatial control of sensory adaptation modulates mechanosensing in Pseudomonas aeruginosa. bioRxiv. 2024 Feb 27. Patino R, Kühn MJ, Macmillan H, Inclan YF, Chavez I, Von Dollen J, Johnson JR, Swaney DL, Krogan NJ, Persat A, Engel JN. PMID: 38464290; PMCID: PMC10925122.
      View in: PubMed   Mentions:
    29. The Chlamydia trachomatis Inc Tri1 interacts with TRAF7 to displace native TRAF7 interacting partners. bioRxiv. 2024 Feb 26. Herrera CM, McMahon E, Swaney DL, Sherry J, Pha K, Adams-Boone K, Johnson JR, Krogan NJ, Stevers M, Solomon D, Elwell C, Engel J. PMID: 38464023; PMCID: PMC10925117.
      View in: PubMed   Mentions:
    30. A foundational atlas of autism protein interactions reveals molecular convergence. bioRxiv. 2024 Feb 08. Wang B, Vartak R, Zaltsman Y, Naing ZZC, Hennick KM, Polacco BJ, Bashir A, Eckhardt M, Bouhaddou M, Xu J, Sun N, Lasser MC, Zhou Y, McKetney J, Guiley KZ, Chan U, Kaye JA, Chadha N, Cakir M, Gordon M, Khare P, Drake S, Drury V, Burke DF, Gonzalez S, Alkhairy S, Thomas R, Lam S, Morris M, Bader E, Seyler M, Baum T, Krasnoff R, Wang S, Pham P, Arbalaez J, Pratt D, Chag S, Mahmood N, Rolland T, Bourgeron T, Finkbeiner S, Swaney DL, Bandyopadhay S, Ideker T, Beltrao P, Willsey HR, Obernier K, Nowakowski TJ, Hüttenhain R, State MW, Willsey AJ, Krogan NJ. PMID: 38076945; PMCID: PMC10705567.
      View in: PubMed   Mentions:
    31. Protein interaction map of APOBEC3 enzyme family reveals deamination-independent role in cellular function. bioRxiv. 2024 Feb 06. Jang GM, Sudarsan AKA, Shayeganmehr A, Munhoz EP, Lao R, Gaba A, Rodríguez MG, Love RP, Polacco BJ, Zhou Y, Krogan NJ, Kaake RM, Chelico L. PMID: 38370690; PMCID: PMC10871184.
      View in: PubMed   Mentions:
    32. Epigenetic reprogramming shapes the cellular landscape of schwannoma. Nat Commun. 2024 Jan 12; 15(1):476. Liu SJ, Casey-Clyde T, Cho NW, Swinderman J, Pekmezci M, Dougherty MC, Foster K, Chen WC, Villanueva-Meyer JE, Swaney DL, Vasudevan HN, Choudhury A, Pak J, Breshears JD, Lang UE, Eaton CD, Hiam-Galvez KJ, Stevenson E, Chen KH, Lien BV, Wu D, Braunstein SE, Sneed PK, Magill ST, Lim D, McDermott MW, Berger MS, Perry A, Krogan NJ, Hansen MR, Spitzer MH, Gilbert L, Theodosopoulos PV, Raleigh DR. PMID: 38216587; PMCID: PMC10786948.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. Cross-family small GTPase ubiquitination by the intracellular pathogen Legionella pneumophila. Mol Biol Cell. 2024 Mar 01; 35(3):ar27. Steinbach A, Bhadkamkar V, Jimenez-Morales D, Stevenson E, Jang GM, Krogan NJ, Swaney DL, Mukherjee S. PMID: 38117589; PMCID: PMC10916871.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    34. Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy. Cell Rep. 2023 12 26; 42(12):113529. Krause GJ, Kirchner P, Stiller B, Morozova K, Diaz A, Chen KH, Krogan NJ, Agullo-Pascual E, Clement CC, Lindenau K, Swaney DL, Dilipkumar S, Bravo-Cordero JJ, Santambrogio L, Cuervo AM. PMID: 38060380; PMCID: PMC10807933.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    35. Hepatitis C virus infects and perturbs liver stem cells. mBio. 2023 Dec 19; 14(6):e0131823. Meyers NL, Ashuach T, Lyons DE, Khalid MM, Simoneau CR, Erickson AL, Bouhaddou M, Nguyen TT, Kumar GR, Taha TY, Natarajan V, Baron JL, Neff N, Zanini F, Mahmoudi T, Quake SR, Krogan NJ, Cooper S, McDevitt TC, Yosef N, Ott M. PMID: 37938000; PMCID: PMC10746249.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    36. De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking. Cell. 2023 11 09; 186(23):5041-5053.e19. Chen Z, Shiozaki M, Haas KM, Skinner WM, Zhao S, Guo C, Polacco BJ, Yu Z, Krogan NJ, Lishko PV, Kaake RM, Vale RD, Agard DA. PMID: 37865089; PMCID: PMC10842264.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    37. The multi-lineage transcription factor ISL1 controls cardiomyocyte cell fate through interaction with NKX2.5. Stem Cell Reports. 2023 11 14; 18(11):2138-2153. Maven BEJ, Gifford CA, Weilert M, Gonzalez-Teran B, Hüttenhain R, Pelonero A, Ivey KN, Samse-Knapp K, Kwong W, Gordon D, McGregor M, Nishino T, Okorie E, Rossman S, Costa MW, Krogan NJ, Zeitlinger J, Srivastava D. PMID: 37863045; PMCID: PMC10679653.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
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    164. Dynamic post-translational modification profiling of Mycobacterium tuberculosis-infected primary macrophages. Elife. 2020 01 17; 9. Budzik JM, Swaney DL, Jimenez-Morales D, Johnson JR, Garelis NE, Repasy T, Roberts AW, Popov LM, Parry TJ, Pratt D, Ideker T, Krogan NJ, Cox JS. PMID: 31951200; PMCID: PMC7030789.
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    165. Splicing Defects of the Profilin Gene Alter Actin Dynamics in an S. pombe SMN Mutant. iScience. 2020 Jan 24; 23(1):100809. Antoine M, Patrick KL, Soret J, Duc P, Rage F, Cacciottolo R, Nissen KE, Cauchi RJ, Krogan NJ, Guthrie C, Gachet Y, Bordonné R. PMID: 31927482; PMCID: PMC6957872.
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    170. Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen. Cell Host Microbe. 2019 10 09; 26(4):551-563.e6. Jeng EE, Bhadkamkar V, Ibe NU, Gause H, Jiang L, Chan J, Jian R, Jimenez-Morales D, Stevenson E, Krogan NJ, Swaney DL, Snyder MP, Mukherjee S, Bassik MC. PMID: 31540829; PMCID: PMC6800164.
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    174. Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers. Cell Rep. 2019 08 27; 28(9):2317-2330.e8. Chatterjee N, Pazarentzos E, Mayekar MK, Gui P, Allegakoen DV, Hrustanovic G, Olivas V, Lin L, Verschueren E, Johnson JR, Hofree M, Yan JJ, Newton BW, Dollen JV, Earnshaw CH, Flanagan J, Chan E, Asthana S, Ideker T, Wu W, Suzuki J, Barad BA, Kirichok Y, Fraser JS, Weiss WA, Krogan NJ, Tulpule A, Sabnis AJ, Bivona TG. PMID: 31461649; PMCID: PMC6728083.
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    180. ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection. Cell Host Microbe. 2019 07 10; 26(1):86-99.e7. Hüttenhain R, Xu J, Burton LA, Gordon DE, Hultquist JF, Johnson JR, Satkamp L, Hiatt J, Rhee DY, Baek K, Crosby DC, Frankel AD, Marson A, Harper JW, Alpi AF, Schulman BA, Gross JD, Krogan NJ. PMID: 31253590; PMCID: PMC7153695.
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    191. Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication. Cell. 2018 12 13; 175(7):1917-1930.e13. Batra J, Hultquist JF, Liu D, Shtanko O, Von Dollen J, Satkamp L, Jang GM, Luthra P, Schwarz TM, Small GI, Arnett E, Anantpadma M, Reyes A, Leung DW, Kaake R, Haas P, Schmidt CB, Schlesinger LS, LaCount DJ, Davey RA, Amarasinghe GK, Basler CF, Krogan NJ. PMID: 30550789; PMCID: PMC6366944.
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    204. Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis. Sci Rep. 2018 Jul 20; 8(1):11001. Paulo E, Wu D, Wang Y, Zhang Y, Wu Y, Swaney DL, Soucheray M, Jimenez-Morales D, Chawla A, Krogan NJ, Wang B. PMID: 30030465; PMCID: PMC6054673.
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