Nicholas Artinian, MD

TitleResident Physician
InstitutionUniversity of California San Francisco
DepartmentDean's Office
Address155 N Fresno St
Fresno CA 93701
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    1. Artinian N, Cloninger C, Holmes B, Benavides-Serrato A, Bashir T, Gera J. Phosphorylation of the Hippo Pathway Component AMOTL2 by the mTORC2 Kinase Promotes YAP Signaling, Resulting in Enhanced Glioblastoma Growth and Invasiveness. J Biol Chem. 2015 Aug 07; 290(32):19387-401. PMID: 25998128; PMCID: PMC4528104.
    2. Benavides-Serrato A, Anderson L, Holmes B, Cloninger C, Artinian N, Bashir T, Gera J. mTORC2 modulates feedback regulation of p38 MAPK activity via DUSP10/MKP5 to confer differential responses to PP242 in glioblastoma. Genes Cancer. 2014 Nov; 5(11-12):393-406. PMID: 25568665; PMCID: PMC4279437.
    3. Bashir T, Cloninger C, Artinian N, Anderson L, Bernath A, Holmes B, Benavides-Serrato A, Sabha N, Nishimura RN, Guha A, Gera J. Conditional astroglial Rictor overexpression induces malignant glioma in mice. PLoS One. 2012; 7(10):e47741. PMID: 23077666; PMCID: PMC3471885.
    4. Holmes B, Artinian N, Anderson L, Martin J, Masri J, Cloninger C, Bernath A, Bashir T, Benavides-Serrato A, Gera J. Protor-2 interacts with tristetraprolin to regulate mRNA stability during stress. Cell Signal. 2012 Jan; 24(1):309-15. PMID: 21964062; PMCID: PMC3205320.
    5. Cloninger C, Bernath A, Bashir T, Holmes B, Artinian N, Ruegg T, Anderson L, Masri J, Lichtenstein A, Gera J. Inhibition of SAPK2/p38 enhances sensitivity to mTORC1 inhibition by blocking IRES-mediated translation initiation in glioblastoma. Mol Cancer Ther. 2011 Dec; 10(12):2244-56. PMID: 21911485; PMCID: PMC3237929.
    6. Martin J, Masri J, Cloninger C, Holmes B, Artinian N, Funk A, Ruegg T, Anderson L, Bashir T, Bernath A, Lichtenstein A, Gera J. Phosphomimetic substitution of heterogeneous nuclear ribonucleoprotein A1 at serine 199 abolishes AKT-dependent internal ribosome entry site-transacting factor (ITAF) function via effects on strand annealing and results in mammalian target of rapamycin complex 1 (mTORC1) inhibitor sensitivity. J Biol Chem. 2011 May 06; 286(18):16402-13. PMID: 21454539; PMCID: PMC3091246.
    7. Vartanian R, Masri J, Martin J, Cloninger C, Holmes B, Artinian N, Funk A, Ruegg T, Gera J. AP-1 regulates cyclin D1 and c-MYC transcription in an AKT-dependent manner in response to mTOR inhibition: role of AIP4/Itch-mediated JUNB degradation. Mol Cancer Res. 2011 Jan; 9(1):115-30. PMID: 21135252; PMCID: PMC3105464.
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