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Nick Castello, PhD

Title(s)Research Associate III, Gladstone Institutes
SchoolSchool of Medicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Czirr E, Castello NA, Mosher KI, Castellano JM, Hinkson IV, Lucin KM, Baeza-Raja B, Ryu JK, Li L, Farina SN, Belichenko NP, Longo FM, Akassoglou K, Britschgi M, Cirrito JR, Wyss-Coray T. Microglial complement receptor 3 regulates brain Aß levels through secreted proteolytic activity. J Exp Med. 2017 04 03; 214(4):1081-1092. PMID: 28298456.
      View in: PubMed
    2. Myczek K, Yeung ST, Castello N, Baglietto-Vargas D, LaFerla FM. Hippocampal adaptive response following extensive neuronal loss in an inducible transgenic mouse model. PLoS One. 2014; 9(9):e106009. PMID: 25184527; PMCID: PMC4153578.
    3. Lin AJ, Liu G, Castello NA, Yeh JJ, Rahimian R, Lee G, Tsay V, Durkin AJ, Choi B, LaFerla FM, Chen Z, Green KN, Tromberg BJ. Optical imaging in an Alzheimer's mouse model reveals amyloid-ß-dependent vascular impairment. Neurophotonics. 2014 Jul; 1(1):011005. PMID: 25133200.
      View in: PubMed
    4. Blurton-Jones M, Spencer B, Michael S, Castello NA, Agazaryan AA, Davis JL, Müller FJ, Loring JF, Masliah E, LaFerla FM. Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models. Stem Cell Res Ther. 2014 Apr 16; 5(2):46. PMID: 25022790; PMCID: PMC4055090.
    5. Castello NA, Nguyen MH, Tran JD, Cheng D, Green KN, LaFerla FM. 7,8-Dihydroxyflavone, a small molecule TrkB agonist, improves spatial memory and increases thin spine density in a mouse model of Alzheimer disease-like neuronal loss. PLoS One. 2014; 9(3):e91453. PMID: 24614170; PMCID: PMC3948846.
    6. Chabrier MA, Cheng D, Castello NA, Green KN, LaFerla FM. Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease. Neurobiol Dis. 2014 Apr; 64:107-17. PMID: 24440055; PMCID: PMC4072239.
    7. Lin AJ, Castello NA, Lee G, Green KN, Durkin AJ, Choi B, LaFerla F, Tromberg BJ. In vivo optical signatures of neuronal death in a mouse model of Alzheimer's disease. Lasers Surg Med. 2014 Jan; 46(1):27-33. PMID: 24284732; PMCID: PMC4001800.
    8. Medeiros R, Castello NA, Cheng D, Kitazawa M, Baglietto-Vargas D, Green KN, Esbenshade TA, Bitner RS, Decker MW, LaFerla FM. a7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles. Am J Pathol. 2014 Feb; 184(2):520-9. PMID: 24269557.
      View in: PubMed
    9. Castello NA, Green KN, LaFerla FM. Genetic knockdown of brain-derived neurotrophic factor in 3xTg-AD mice does not alter Aß or tau pathology. PLoS One. 2012; 7(8):e39566. PMID: 22870188; PMCID: PMC3411687.
    10. Berchtold NC, Castello N, Cotman CW. Exercise and time-dependent benefits to learning and memory. Neuroscience. 2010 May 19; 167(3):588-97. PMID: 20219647; PMCID: PMC2857396.
    11. Blurton-Jones M, Kitazawa M, Martinez-Coria H, Castello NA, Müller FJ, Loring JF, Yamasaki TR, Poon WW, Green KN, LaFerla FM. Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32):13594-9. PMID: 19633196.
      View in: PubMed
    12. Roozendaal B, Castello NA, Vedana G, Barsegyan A, McGaugh JL. Noradrenergic activation of the basolateral amygdala modulates consolidation of object recognition memory. Neurobiol Learn Mem. 2008 Oct; 90(3):576-9. PMID: 18657626; PMCID: PMC2572617.