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Nick Castello, PhD

Title(s)Senior Research Associate, Gladstone Institutes
SchoolSchool of Medicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD. Neuron. 2019 09 04; 103(5):802-819.e11. Fang MY, Markmiller S, Vu AQ, Javaherian A, Dowdle WE, Jolivet P, Bushway PJ, Castello NA, Baral A, Chan MY, Linsley JW, Linsley D, Mercola M, Finkbeiner S, Lecuyer E, Lewcock JW, Yeo GW. PMID: 31272829.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    2. Microglial complement receptor 3 regulates brain Aß levels through secreted proteolytic activity. J Exp Med. 2017 04 03; 214(4):1081-1092. Czirr E, Castello NA, Mosher KI, Castellano JM, Hinkson IV, Lucin KM, Baeza-Raja B, Ryu JK, Li L, Farina SN, Belichenko NP, Longo FM, Akassoglou K, Britschgi M, Cirrito JR, Wyss-Coray T. PMID: 28298456.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    3. Hippocampal adaptive response following extensive neuronal loss in an inducible transgenic mouse model. PLoS One. 2014; 9(9):e106009. Myczek K, Yeung ST, Castello N, Baglietto-Vargas D, LaFerla FM. PMID: 25184527.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    4. Optical imaging in an Alzheimer's mouse model reveals amyloid-ß-dependent vascular impairment. Neurophotonics. 2014 Jul; 1(1):011005. Lin AJ, Liu G, Castello NA, Yeh JJ, Rahimian R, Lee G, Tsay V, Durkin AJ, Choi B, LaFerla FM, Chen Z, Green KN, Tromberg BJ. PMID: 25133200.
      View in: PubMed   Mentions:
    5. Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models. Stem Cell Res Ther. 2014 Apr 16; 5(2):46. Blurton-Jones M, Spencer B, Michael S, Castello NA, Agazaryan AA, Davis JL, Müller FJ, Loring JF, Masliah E, LaFerla FM. PMID: 25022790.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    6. 7,8-Dihydroxyflavone, a small molecule TrkB agonist, improves spatial memory and increases thin spine density in a mouse model of Alzheimer disease-like neuronal loss. PLoS One. 2014; 9(3):e91453. Castello NA, Nguyen MH, Tran JD, Cheng D, Green KN, LaFerla FM. PMID: 24614170.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    7. Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease. Neurobiol Dis. 2014 Apr; 64:107-17. Chabrier MA, Cheng D, Castello NA, Green KN, LaFerla FM. PMID: 24440055.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    8. In vivo optical signatures of neuronal death in a mouse model of Alzheimer's disease. Lasers Surg Med. 2014 Jan; 46(1):27-33. Lin AJ, Castello NA, Lee G, Green KN, Durkin AJ, Choi B, LaFerla F, Tromberg BJ. PMID: 24284732.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    9. a7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles. Am J Pathol. 2014 Feb; 184(2):520-9. Medeiros R, Castello NA, Cheng D, Kitazawa M, Baglietto-Vargas D, Green KN, Esbenshade TA, Bitner RS, Decker MW, LaFerla FM. PMID: 24269557.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    10. Genetic knockdown of brain-derived neurotrophic factor in 3xTg-AD mice does not alter Aß or tau pathology. PLoS One. 2012; 7(8):e39566. Castello NA, Green KN, LaFerla FM. PMID: 22870188.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    11. Exercise and time-dependent benefits to learning and memory. Neuroscience. 2010 May 19; 167(3):588-97. Berchtold NC, Castello N, Cotman CW. PMID: 20219647.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    12. Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32):13594-9. Blurton-Jones M, Kitazawa M, Martinez-Coria H, Castello NA, Müller FJ, Loring JF, Yamasaki TR, Poon WW, Green KN, LaFerla FM. PMID: 19633196.
      View in: PubMed   Mentions: 216     Fields:    Translation:AnimalsCells
    13. Noradrenergic activation of the basolateral amygdala modulates consolidation of object recognition memory. Neurobiol Learn Mem. 2008 Oct; 90(3):576-9. Roozendaal B, Castello NA, Vedana G, Barsegyan A, McGaugh JL. PMID: 18657626.
      View in: PubMed   Mentions: 62     Fields:    Translation:Animals
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