 Nicholas Polizzi, PhD
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| Title(s) | Postdoctoral Scholar, Pharmaceutical Chemistry |
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| School | School of Pharmacy |
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| vCard | Download vCard |
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 Bibliographic
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Shan B, Nayak A, Williams OF, Yost DC, Polizzi NF, Liu Y, Zhou N, Kanai Y, Moran AM, Therien MJ, Meyer TJ. Excitation energy-dependent photocurrent switching in a single-molecule photodiode. Proc Natl Acad Sci U S A. 2019 Aug 13; 116(33):16198-16203. PMID: 31366631.
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Tan SK, Fong KP, Polizzi NF, Sternisha A, Slusky JSG, Yoon K, DeGrado WF, Bennett JS. Modulating Integrin aIIbß3 Activity through Mutagenesis of Allosterically Regulated Intersubunit Contacts. Biochemistry. 2019 Jul 30; 58(30):3251-3259. PMID: 31264850.
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Thomaston JL, Wu Y, Polizzi N, Liu L, Wang J, DeGrado WF. X-ray Crystal Structure of the Influenza A M2 Proton Channel S31N Mutant in Two Conformational States: An Open and Shut Case. J Am Chem Soc. 2019 Jul 24; 141(29):11481-11488. PMID: 31184871.
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Polizzi NF, Jiang T, Beratan DN, Therien MJ. Engineering opposite electronic polarization of singlet and triplet states increases the yield of high-energy photoproducts. Proc Natl Acad Sci U S A. 2019 Jul 16; 116(29):14465-14470. PMID: 31182609.
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Yang B, Wang N, Schnier PD, Zheng F, Zhu H, Polizzi NF, Ittuveetil A, Saikam V, DeGrado WF, Wang Q, Wang PG, Wang L. Genetically Introducing Biochemically Reactive Amino Acids Dehydroalanine and Dehydrobutyrine in Proteins. J Am Chem Soc. 2019 May 15; 141(19):7698-7703. PMID: 31038942.
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Bisignano P, Ghezzi C, Jo H, Polizzi NF, Althoff T, Kalyanaraman C, Friemann R, Jacobson MP, Wright EM, Grabe M. Inhibitor binding mode and allosteric regulation of Na+-glucose symporters. Nat Commun. 2018 12 07; 9(1):5245. PMID: 30532032.
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Thomaston JL, Polizzi NF, Konstantinidi A, Wang J, Kolocouris A, DeGrado WF. Inhibitors of the M2 Proton Channel Engage and Disrupt Transmembrane Networks of Hydrogen-Bonded Waters. J Am Chem Soc. 2018 11 14; 140(45):15219-15226. PMID: 30165017.
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Bai Y, Olivier JH, Yoo H, Polizzi NF, Park J, Rawson J, Therien MJ. Molecular Road Map to Tuning Ground State Absorption and Excited State Dynamics of Long-Wavelength Absorbers. J Am Chem Soc. 2017 11 22; 139(46):16946-16958. PMID: 29043788.
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Polizzi NF, Wu Y, Lemmin T, Maxwell AM, Zhang SQ, Rawson J, Beratan DN, Therien MJ, DeGrado WF. De novo design of a hyperstable non-natural protein-ligand complex with sub-Å accuracy. Nat Chem. 2017 12; 9(12):1157-1164. PMID: 29168496.
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Jiang T, Polizzi NF, Rawson J, Therien MJ. Engineering High-Potential Photo-oxidants with Panchromatic Absorption. J Am Chem Soc. 2017 06 28; 139(25):8412-8415. PMID: 28613070.
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Lee M, Wang T, Makhlynets OV, Wu Y, Polizzi NF, Wu H, Gosavi PM, Stöhr J, Korendovych IV, DeGrado WF, Hong M. Zinc-binding structure of a catalytic amyloid from solid-state NMR. Proc Natl Acad Sci U S A. 2017 06 13; 114(24):6191-6196. PMID: 28566494.
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Polizzi NF, Therien MJ, Beratan DN. Mean First-Passage Times in Biology. Isr J Chem. 2016 Nov; 56(9-10):816-824. PMID: 29081538.
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Zheng L, Polizzi NF, Dave AR, Migliore A, Beratan DN. Where Is the Electronic Oscillator Strength? Mapping Oscillator Strength across Molecular Absorption Spectra. J Phys Chem A. 2016 Mar 24; 120(11):1933-43. PMID: 26950828.
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Polizzi NF, Eibling MJ, Perez-Aguilar JM, Rawson J, Lanci CJ, Fry HC, Beratan DN, Saven JG, Therien MJ. Photoinduced Electron Transfer Elicits a Change in the Static Dielectric Constant of a de Novo Designed Protein. J Am Chem Soc. 2016 Feb 24; 138(7):2130-3. PMID: 26840013.
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Nicholas F. Polizzi, David N. Beratan. Open-Access, Interactive Explorations for Teaching and Learning Quantum Dynamics. Journal of Chemical Education. 2015 Dec 8; 92(12):2161-2164.
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Polizzi NF, Migliore A, Therien MJ, Beratan DN. Defusing redox bombs? Proc Natl Acad Sci U S A. 2015 Sep 01; 112(35):10821-2. PMID: 26290579.
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Beratan DN, Liu C, Migliore A, Polizzi NF, Skourtis SS, Zhang P, Zhang Y. Charge transfer in dynamical biosystems, or the treachery of (static) images. Acc Chem Res. 2015 Feb 17; 48(2):474-81. PMID: 25307316.
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Migliore A, Polizzi NF, Therien MJ, Beratan DN. Biochemistry and theory of proton-coupled electron transfer. Chem Rev. 2014 Apr 09; 114(7):3381-465. PMID: 24684625.
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Polizzi NF, Skourtis SS, Beratan DN. Physical constraints on charge transport through bacterial nanowires. Faraday Discuss. 2012; 155:43-62; discussion 103-14. PMID: 22470966.
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