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Noah Zaitlen, PhD

Title(s)Assistant Professor in Res, Medicine
SchoolSchool of Medicine
AddressLocation Required
Varies CA 00000
Phone415-502-2027
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    Collapse Research 
    Collapse Research Activities and Funding
    Improved methods for inference of genotype-specific response to environmental toxins
    NIH/NIEHS R01ES029929Feb 1, 2019 - Jan 31, 2024
    Role: Co-Principal Investigator
    Epigenetics of Socio-Environmental Effects on Asthma in Minorities
    NIH/NIMHD R56MD013312Sep 25, 2018 - Sep 24, 2019
    Role: Principal Investigator
    (PQ3) A functional genomic approach to identification and interpretation of germline-tumor genetic interactions
    NIH/NCI R01CA227237Jun 8, 2018 - May 31, 2023
    Role: Co-Principal Investigator
    Leveraging Novel Multivariate Methods of Subphenotypes in Genetic Association Studies of Sjogren?s Syndrome
    NIH/NIDCR R03DE025665Sep 2, 2016 - Aug 31, 2018
    Role: Co-Principal Investigator
    Richer Models of Asthma Risk: Bridging the Environment-Genetics Divide
    NIH/NHLBI K25HL121295Aug 1, 2014 - Oct 31, 2019
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Whole-Genome and RNA Sequencing Reveal Variation and Transcriptomic Coordination in the Developing Human Prefrontal Cortex. Cell Rep. 2020 Apr 07; 31(1):107489. Werling DM, Pochareddy S, Choi J, An JY, Sheppard B, Peng M, Li Z, Dastmalchi C, Santpere G, Sousa AMM, Tebbenkamp ATN, Kaur N, Gulden FO, Breen MS, Liang L, Gilson MC, Zhao X, Dong S, Klei L, Cicek AE, Buxbaum JD, Adle-Biassette H, Thomas JL, Aldinger KA, O'Day DR, Glass IA, Zaitlen NA, Talkowski ME, Roeder K, State MW, Devlin B, Sanders SJ, Sestan N. PMID: 32268104.
      View in: PubMed   Mentions:    Fields:    
    2. Efficient Estimation and Applications of Cross-Validated Genetic Predictions to Polygenic Risk Scores and Linear Mixed Models. J Comput Biol. 2020 Apr; 27(4):599-612. Mefford J, Park D, Zheng Z, Ko A, Ala-Korpela M, Laakso M, Pajukanta P, Yang J, Witte J, Zaitlen N. PMID: 32077750.
      View in: PubMed   Mentions:    Fields:    
    3. A Robust Method Uncovers Significant Context-Specific Heritability in Diverse Complex Traits. Am J Hum Genet. 2020 01 02; 106(1):71-91. Dahl A, Nguyen K, Cai N, Gandal MJ, Flint J, Zaitlen N. PMID: 31901249.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    4. Estimating the Rate of Cell Type Degeneration from Epigenetic Sequencing of Cell-Free DNA. . 2020 Jan 1; 12074:240-242. Christa Caggiano, Barbara Celona, Fleur Garton, Joel Mefford, Brian Black, Catherine Lomen-Hoerth, Andrew Dahl, Noah Zaitlen. .
      View in: Publisher Site   Mentions:
    5. A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context. Nat Commun. 2019 10 21; 10(1):4788. Gallois A, Mefford J, Ko A, Vaysse A, Julienne H, Ala-Korpela M, Laakso M, Zaitlen N, Pajukanta P, Aschard H. PMID: 31636271.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Reverse GWAS: Using genetics to identify and model phenotypic subtypes. PLoS Genet. 2019 04; 15(4):e1008009. Dahl A, Cai N, Ko A, Laakso M, Pajukanta P, Flint J, Zaitlen N. PMID: 30951530.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. Genetic effects on the commensal microbiota in inflammatory bowel disease patients. PLoS Genet. 2019 03; 15(3):e1008018. Aschard H, Laville V, Tchetgen ET, Knights D, Imhann F, Seksik P, Zaitlen N, Silverberg MS, Cosnes J, Weersma RK, Xavier R, Beaugerie L, Skurnik D, Sokol H. PMID: 30849075.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    8. Tracing cellular heterogeneity in pooled genetic screens via multi-level barcoding. BMC Genomics. 2019 Feb 06; 20(1):107. Boettcher M, Covarrubias S, Biton A, Blau J, Wang H, Zaitlen N, McManus MT. PMID: 30727954.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    9. Adjusting for Principal Components of Molecular Phenotypes Induces Replicating False Positives. Genetics. 2019 04; 211(4):1179-1189. Dahl A, Guillemot V, Mefford J, Aschard H, Zaitlen N. PMID: 30692194.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    10. 22 MOLECULAR GENETIC ANALYSIS SUBDIVIDED BY ADVERSITY EXPOSURE SUGGESTS ETIOLOGIC HETEROGENEITY IN MAJOR DEPRESSION. European Neuropsychopharmacology. 2019 Jan 1; 29:s792-s793. Roseann Peterson, Na Cai, Andy Dahl, Tim Bigdeli, Alexis Edwards, Bradley Webb, Silviu Bacanu, Noah Zaitlen, Jonathan Flint, Kenneth Kendler. .
      View in: Publisher Site   Mentions:
    11. Estimating cross-population genetic correlations of causal effect sizes. Genet Epidemiol. 2019 03; 43(2):180-188. Galinsky KJ, Reshef YA, Finucane HK, Loh PR, Zaitlen N, Patterson NJ, Brown BC, Price AL. PMID: 30474154.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Comparing Ethnicity-Specific Reference Intervals for Clinical Laboratory Tests from EHR Data. The Journal of Applied Laboratory Medicine. 2018 Nov 1; 3(3):366-377. Nadav Rappoport, Hyojung Paik, Boris Oskotsky, Ruth Tor, Elad Ziv, Noah Zaitlen, Atul J. Butte. .
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    13. An Association Mapping Framework To Account for Potential Sex Difference in Genetic Architectures. Genetics. 2018 07; 209(3):685-698. Kang EY, Lee CH, Furlotte NA, Joo JWJ, Kostem E, Zaitlen N, Eskin E, Han B. PMID: 29752291.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Molecular Genetic Analysis Subdivided by Adversity Exposure Suggests Etiologic Heterogeneity in Major Depression. Am J Psychiatry. 2018 06 01; 175(6):545-554. Peterson RE, Cai N, Dahl AW, Bigdeli TB, Edwards AC, Webb BT, Bacanu SA, Zaitlen N, Flint J, Kendler KS. PMID: 29495898.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    15. ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues. Genome Biol. 2018 02 15; 19(1):36. Mangul S, Yang HT, Strauli N, Gruhl F, Porath HT, Hsieh K, Chen L, Daley T, Christenson S, Wesolowska-Andersen A, Spreafico R, Rios C, Eng C, Smith AD, Hernandez RD, Ophoff RA, Santana JR, Levanon EY, Woodruff PG, Burchard E, Seibold MA, Shifman S, Eskin E, Zaitlen N. PMID: 29548336.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    16. Dual gene activation and knockout screen reveals directional dependencies in genetic networks. Nat Biotechnol. 2018 02; 36(2):170-178. Boettcher M, Tian R, Blau JA, Markegard E, Wagner RT, Wu D, Mo X, Biton A, Zaitlen N, Fu H, McCormick F, Kampmann M, McManus MT. PMID: 29334369.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    17. Multiplexed droplet single-cell RNA-sequencing using natural genetic variation. Nat Biotechnol. 2018 01; 36(1):89-94. Kang HM, Subramaniam M, Targ S, Nguyen M, Maliskova L, McCarthy E, Wan E, Wong S, Byrnes L, Lanata CM, Gate RE, Mostafavi S, Marson A, Zaitlen N, Criswell LA, Ye CJ. PMID: 29227470.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    18. An ancestry-based approach for detecting interactions. Genet Epidemiol. 2018 02; 42(1):49-63. Park DS, Eskin I, Kang EY, Gamazon ER, Eng C, Gignoux CR, Galanter JM, Burchard E, Ye CJ, Aschard H, Eskin E, Halperin E, Zaitlen N. PMID: 29114909.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    19. Covariate selection for association screening in multiphenotype genetic studies. Nat Genet. 2017 Dec; 49(12):1789-1795. Aschard H, Guillemot V, Vilhjalmsson B, Patel CJ, Skurnik D, Ye CJ, Wolpin B, Kraft P, Zaitlen N. PMID: 29038595.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    20. CRISPR-Cas9-mediated functional dissection of 3'-UTRs. Nucleic Acids Res. 2017 Oct 13; 45(18):10800-10810. Zhao W, Siegel D, Biton A, Tonqueze OL, Zaitlen N, Ahituv N, Erle DJ. PMID: 28985357.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    21. Heritable natural variation of an anxiety-like behavior in larval zebrafish. J Neurogenet. 2017 09; 31(3):138-148. Wagle M, Nguyen J, Lee S, Zaitlen N, Guo S. PMID: 28678579.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    22. GLINT: a user-friendly toolset for the analysis of high-throughput DNA-methylation array data. Bioinformatics. 2017 Jun 15; 33(12):1870-1872. Rahmani E, Yedidim R, Shenhav L, Schweiger R, Weissbrod O, Zaitlen N, Halperin E. PMID: 28177067.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    23. Correction: Pleiotropic Mechanisms Indicated for Sex Differences in Autism. PLoS Genet. 2017 Jun; 13(6):e1006831. Mitra I, Tsang K, Ladd-Acosta C, Croen LA, Aldinger KA, Hendren RL, Traglia M, Lavillaureix A, Zaitlen N, Oldham MC, Levitt P, Nelson S, Amaral DG, Hertz-Picciotto I, Fallin MD, Weiss LA. PMID: 28591140.
      View in: PubMed   Mentions:    Fields:    
    24. Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk. PLoS Genet. 2017 Mar; 13(3):e1006690. Hoffman JD, Graff RE, Emami NC, Tai CG, Passarelli MN, Hu D, Huntsman S, Hadley D, Leong L, Majumdar A, Zaitlen N, Ziv E, Witte JS. PMID: 28362817.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    25. Correcting for cell-type heterogeneity in DNA methylation: a comprehensive evaluation. Nat Methods. 2017 02 28; 14(3):218-219. Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E. PMID: 28245214.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    26. Genome-wide methylation data mirror ancestry information. Epigenetics Chromatin. 2017; 10:1. Rahmani E, Shenhav L, Schweiger R, Yousefi P, Huen K, Eskenazi B, Eng C, Huntsman S, Hu D, Galanter J, Oh SS, Waldenberger M, Strauch K, Grallert H, Meitinger T, Gieger C, Holland N, Burchard EG, Zaitlen N, Halperin E. PMID: 28149326.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    27. PhAT-QTL: A Phase-Aware Test for QTL Detection. Bioinformatics Research and Applications. 2017 Jan 1; 10330:150-161. Meena Subramaniam, Noah Zaitlen, Jimmie Ye. .
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    28. T6 An Investigation Of Assortative Mating Patterns And Underlying Genetic Correlates In Parents Of Offspring With Asd. European Neuropsychopharmacology. 2017 Jan 1; 27:s435. Aaron Besterman, Jeffrey Mandell, Noah Zaitlen. .
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    29. Mixed Model Association with Family-Biased Case-Control Ascertainment. Am J Hum Genet. 2017 Jan 05; 100(1):31-39. Hayeck TJ, Loh PR, Pollack S, Gusev A, Patterson N, Zaitlen NA, Price AL. PMID: 28017371.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Genetic Mechanisms Leading to Sex Differences Across Common Diseases and Anthropometric Traits. Genetics. 2017 02; 205(2):979-992. Traglia M, Bseiso D, Gusev A, Adviento B, Park DS, Mefford JA, Zaitlen N, Weiss LA. PMID: 27974502.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    31. The Effects of Migration and Assortative Mating on Admixture Linkage Disequilibrium. Genetics. 2017 01; 205(1):375-383. Zaitlen N, Huntsman S, Hu D, Spear M, Eng C, Oh SS, White MJ, Mak A, Davis A, Meade K, Brigino-Buenaventura E, LeNoir MA, Bibbins-Domingo K, Burchard EG, Halperin E. PMID: 27879348.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. Pleiotropic Mechanisms Indicated for Sex Differences in Autism. PLoS Genet. 2016 11; 12(11):e1006425. Mitra I, Tsang K, Ladd-Acosta C, Croen LA, Aldinger KA, Hendren RL, Traglia M, Lavillaureix A, Zaitlen N, Oldham MC, Levitt P, Nelson S, Amaral DG, Hertz-Picciotto I, Fallin MD, Weiss LA. PMID: 27846226.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    33. Transethnic Genetic-Correlation Estimates from Summary Statistics. Am J Hum Genet. 2016 07 07; 99(1):76-88. Brown BC, Ye CJ, Price AL, Zaitlen N. PMID: 27321947.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    34. Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants. Genome Res. 2016 07; 26(7):863-73. Uricchio LH, Zaitlen NA, Ye CJ, Witte JS, Hernandez RD. PMID: 27197206.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    35. Local Joint Testing Improves Power and Identifies Hidden Heritability in Association Studies. Genetics. 2016 07; 203(3):1105-16. Brown BC, Price AL, Patsopoulos NA, Zaitlen N. PMID: 27182951.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies. Nat Methods. 2016 05; 13(5):443-5. Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E. PMID: 27018579.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    37. A Novel Test for Detecting SNP-SNP Interactions in Case-Only Trio Studies. Genetics. 2016 Apr; 202(4):1289-97. Balliu B, Zaitlen N. PMID: 26865367.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    38. Comment: A Human Genetics Perspective. Journal of the American Statistical Association. 2016 Jan 2; 111(513):124-127. Joel A. Mefford, Noah A. Zaitlen, John S. Witte. .
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    39. Genetic and socioeconomic study of mate choice in Latinos reveals novel assortment patterns. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):13621-6. Zou JY, Park DS, Burchard EG, Torgerson DG, Pino-Yanes M, Song YS, Sankararaman S, Halperin E, Zaitlen N. PMID: 26483472.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    40. Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors. Hum Mol Genet. 2015 Dec 20; 24(25):7421-31. Caswell JL, Camarda R, Zhou AY, Huntsman S, Hu D, Brenner SE, Zaitlen N, Goga A, Ziv E. PMID: 26472073.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    41. Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. Am J Hum Genet. 2015 Oct 01; 97(4):576-92. Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, Genovese G, Loh PR, Bhatia G, Do R, Hayeck T, Won HH, Kathiresan S, Pato M, Pato C, Tamimi R, Stahl E, Zaitlen N, Pasaniuc B, Belbin G, Kenny EE, Schierup MH, De Jager P, Patsopoulos NA, McCarroll S, Daly M, Purcell S, Chasman D, Neale B, Goddard M, Visscher PM, Kraft P, Patterson N, Price AL. PMID: 26430803.
      View in: PubMed   Mentions: 102     Fields:    Translation:Humans
    42. Adapt-Mix: learning local genetic correlation structure improves summary statistics-based analyses. Bioinformatics. 2015 Jun 15; 31(12):i181-9. Park DS, Brown B, Eng C, Huntsman S, Hu D, Torgerson DG, Burchard EG, Zaitlen N. PMID: 26072481.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    43. The landscape of genomic imprinting across diverse adult human tissues. Genome Res. 2015 Jul; 25(7):927-36. Baran Y, Subramaniam M, Biton A, Tukiainen T, Tsang EK, Rivas MA, Pirinen M, Gutierrez-Arcelus M, Smith KS, Kukurba KR, Zhang R, Eng C, Torgerson DG, Urbanek C, Li JB, Rodriguez-Santana JR, Burchard EG, Seibold MA, MacArthur DG, Montgomery SB, Zaitlen NA, Lappalainen T. PMID: 25953952.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    44. Mixed model with correction for case-control ascertainment increases association power. Am J Hum Genet. 2015 May 07; 96(5):720-30. Hayeck TJ, Zaitlen NA, Loh PR, Vilhjalmsson B, Pollack S, Gusev A, Yang J, Chen GB, Goddard ME, Visscher PM, Patterson N, Price AL. PMID: 25892111.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    45. PIGS: improved estimates of identity-by-descent probabilities by probabilistic IBD graph sampling. BMC Bioinformatics. 2015; 16 Suppl 5:S9. Park DS, Baran Y, Hormozdiari F, Eng C, Torgerson DG, Burchard EG, Zaitlen N. PMID: 25860540.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    46. Variation in predictive ability of common genetic variants by established strata: the example of breast cancer and age. Epidemiology. 2015 Jan; 26(1):51-8. Aschard H, Zaitlen N, Lindström S, Kraft P. PMID: 25380502.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    47. Genetic and environmental components of family history in type 2 diabetes. Hum Genet. 2015 Feb; 134(2):259-67. Cornelis MC, Zaitlen N, Hu FB, Kraft P, Price AL. PMID: 25543539.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    48. Leveraging population admixture to characterize the heritability of complex traits. Nat Genet. 2014 Dec; 46(12):1356-62. Zaitlen N, Pasaniuc B, Sankararaman S, Bhatia G, Zhang J, Gusev A, Young T, Tandon A, Pollack S, Vilhjálmsson BJ, Assimes TL, Berndt SI, Blot WJ, Chanock S, Franceschini N, Goodman PG, He J, Hennis AJ, Hsing A, Ingles SA, Isaacs W, Kittles RA, Klein EA, Lange LA, Nemesure B, Patterson N, Reich D, Rybicki BA, Stanford JL, Stevens VL, Strom SS, Whitsel EA, Witte JS, Xu J, Haiman C, Wilson JG, Kooperberg C, Stram D, Reiner AP, Tang H, Price AL. PMID: 25383972.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    49. Intersection of population variation and autoimmunity genetics in human T cell activation. Science. 2014 Sep 12; 345(6202):1254665. Ye CJ, Feng T, Kwon HK, Raj T, Wilson MT, Asinovski N, McCabe C, Lee MH, Frohlich I, Paik HI, Zaitlen N, Hacohen N, Stranger B, De Jager P, Mathis D, Regev A, Benoist C. PMID: 25214635.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    50. Fast and accurate imputation of summary statistics enhances evidence of functional enrichment. Bioinformatics. 2014 Oct 15; 30(20):2906-14. Pasaniuc B, Zaitlen N, Shi H, Bhatia G, Gusev A, Pickrell J, Hirschhorn J, Strachan DP, Patterson N, Price AL. PMID: 24990607.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    51. Massively parallel functional annotation of 3' untranslated regions. Nat Biotechnol. 2014 Apr; 32(4):387-91. Zhao W, Pollack JL, Blagev DP, Zaitlen N, McManus MT, Erle DJ. PMID: 24633241.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    52. Genotyping Common and Rare Variation Using Overlapping Pool Sequencing. Bioinformatics. 2014 Feb 28; 217-233. Dan He, Noah Zaitlen, Bogdan Pasaniuc, Eleazar Eskin, Eran Halperin. .
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    53. Advantages and pitfalls in the application of mixed-model association methods. Nat Genet. 2014 Feb; 46(2):100-6. Yang J, Zaitlen NA, Goddard ME, Visscher PM, Price AL. PMID: 24473328.
      View in: PubMed   Mentions: 169     Fields:    Translation:Humans
    54. Quantifying missing heritability at known GWAS loci. PLoS Genet. 2013; 9(12):e1003993. Gusev A, Bhatia G, Zaitlen N, Vilhjalmsson BJ, Diogo D, Stahl EA, Gregersen PK, Worthington J, Klareskog L, Raychaudhuri S, Plenge RM, Pasaniuc B, Price AL. PMID: 24385918.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    55. Genome-wide association study of ancestry-specific TB risk in the South African Coloured population. Hum Mol Genet. 2014 Feb 01; 23(3):796-809. Chimusa ER, Zaitlen N, Daya M, Möller M, van Helden PD, Mulder NJ, Price AL, Hoal EG. PMID: 24057671.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    56. Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits. PLoS Genet. 2013 May; 9(5):e1003520. Zaitlen N, Kraft P, Patterson N, Pasaniuc B, Bhatia G, Pollack S, Price AL. PMID: 23737753.
      View in: PubMed   Mentions: 108     Fields:    Translation:Humans
    57. Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation. Bioinformatics. 2013 Jun 01; 29(11):1407-15. Pasaniuc B, Sankararaman S, Torgerson DG, Gignoux C, Zaitlen N, Eng C, Rodriguez-Cintron W, Chapela R, Ford JG, Avila PC, Rodriguez-Santana J, Chen GK, Le Marchand L, Henderson B, Reich D, Haiman CA, Gonzàlez Burchard E, Halperin E. PMID: 23572411.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    58. A nonparametric test to detect quantitative trait loci where the phenotypic distribution differs by genotypes. Genet Epidemiol. 2013 May; 37(4):323-33. Aschard H, Zaitlen N, Tamimi RM, Lindström S, Kraft P. PMID: 23512279.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    59. Response to Sul and Eskin. Nat Rev Genet. 2013 Apr; 14(4):300. Price AL, Zaitlen NA, Reich D, Patterson N. PMID: 23438870.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    60. Informed conditioning on clinical covariates increases power in case-control association studies. PLoS Genet. 2012; 8(11):e1003032. Zaitlen N, Lindström S, Pasaniuc B, Cornelis M, Genovese G, Pollack S, Barton A, Bickeböller H, Bowden DW, Eyre S, Freedman BI, Friedman DJ, Field JK, Groop L, Haugen A, Heinrich J, Henderson BE, Hicks PJ, Hocking LJ, Kolonel LN, Landi MT, Langefeld CD, Le Marchand L, Meister M, Morgan AW, Raji OY, Risch A, Rosenberger A, Scherf D, Steer S, Walshaw M, Waters KM, Wilson AG, Wordsworth P, Zienolddiny S, Tchetgen ET, Haiman C, Hunter DJ, Plenge RM, Worthington J, Christiani DC, Schaumberg DA, Chasman DI, Altshuler D, Voight B, Kraft P, Patterson N, Price AL. PMID: 23144628.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    61. Heritability in the genome-wide association era. Hum Genet. 2012 Oct; 131(10):1655-64. Zaitlen N, Kraft P. PMID: 22821350.
      View in: PubMed   Mentions: 63     Fields:    Translation:Humans
    62. Extremely low-coverage sequencing and imputation increases power for genome-wide association studies. Nat Genet. 2012 May 20; 44(6):631-5. Pasaniuc B, Rohland N, McLaren PJ, Garimella K, Zaitlen N, Li H, Gupta N, Neale BM, Daly MJ, Sklar P, Sullivan PF, Bergen S, Moran JL, Hultman CM, Lichtenstein P, Magnusson P, Purcell SM, Haas DW, Liang L, Sunyaev S, Patterson N, de Bakker PI, Reich D, Price AL. PMID: 22610117.
      View in: PubMed   Mentions: 80     Fields:    Translation:Humans
    63. Analysis of case-control association studies with known risk variants. Bioinformatics. 2012 Jul 01; 28(13):1729-37. Zaitlen N, Pasaniuc B, Patterson N, Pollack S, Voight B, Groop L, Altshuler D, Henderson BE, Kolonel LN, Le Marchand L, Waters K, Haiman CA, Stranger BE, Dermitzakis ET, Kraft P, Price AL. PMID: 22556366.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    64. Combining effects from rare and common genetic variants in an exome-wide association study of sequence data. BMC Proc. 2011 Nov 29; 5 Suppl 9:S44. Aschard H, Qiu W, Pasaniuc B, Zaitlen N, Cho MH, Carey V. PMID: 22373328.
      View in: PubMed   Mentions:
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    66. Genotyping common and rare variation using overlapping pool sequencing. BMC Bioinformatics. 2011; 12 Suppl 6:S2. He D, Zaitlen N, Pasaniuc B, Eskin E, Halperin E. PMID: 21989232.
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    67. Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. PLoS Genet. 2011 Apr; 7(4):e1001371. Pasaniuc B, Zaitlen N, Lettre G, Chen GK, Tandon A, Kao WH, Ruczinski I, Fornage M, Siscovick DS, Zhu X, Larkin E, Lange LA, Cupples LA, Yang Q, Akylbekova EL, Musani SK, Divers J, Mychaleckyj J, Li M, Papanicolaou GJ, Millikan RC, Ambrosone CB, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Nyante SJ, Bandera EV, Ingles SA, Press MF, Chanock SJ, Deming SL, Rodriguez-Gil JL, Palmer CD, Buxbaum S, Ekunwe L, Hirschhorn JN, Henderson BE, Myers S, Haiman CA, Reich D, Patterson N, Wilson JG, Price AL. PMID: 21541012.
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    68. Accurate estimation of expression levels of homologous genes in RNA-seq experiments. J Comput Biol. 2011 Mar; 18(3):459-68. Pasaniuc B, Zaitlen N, Halperin E. PMID: 21385047.
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    69. Imputation aware meta-analysis of genome-wide association studies. Genet Epidemiol. 2010 Sep; 34(6):537-42. Zaitlen N, Eskin E. PMID: 20717975.
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    70. New approaches to population stratification in genome-wide association studies. Nat Rev Genet. 2010 Jul; 11(7):459-63. Price AL, Zaitlen NA, Reich D, Patterson N. PMID: 20548291.
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    71. Variance component model to account for sample structure in genome-wide association studies. Nat Genet. 2010 Apr; 42(4):348-54. Kang HM, Sul JH, Service SK, Zaitlen NA, Kong SY, Freimer NB, Sabatti C, Eskin E. PMID: 20208533.
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    72. Leveraging genetic variability across populations for the identification of causal variants. Am J Hum Genet. 2010 Jan; 86(1):23-33. Zaitlen N, Pasaniuc B, Gur T, Ziv E, Halperin E. PMID: 20085711.
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    73. Accurate Estimation of Expression Levels of Homologous Genes in RNA-seq Experiments. Research in Computational Molecular Biology. 2010 Jan 1; 6044:397-409. Bogdan Pasaniuc, Noah Zaitlen, Eran Halperin. .
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    74. An Adaptive and Memory Efficient Algorithm for Genotype Imputation. Research in Computational Molecular Biology. 2009 Jan 1; 5541:482-495. Hyun Min Kang, Noah A. Zaitlen, Buhm Han, Eleazar Eskin. .
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    75. Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nat Genet. 2009 Jan; 41(1):35-46. Sabatti C, Service SK, Hartikainen AL, Pouta A, Ripatti S, Brodsky J, Jones CG, Zaitlen NA, Varilo T, Kaakinen M, Sovio U, Ruokonen A, Laitinen J, Jakkula E, Coin L, Hoggart C, Collins A, Turunen H, Gabriel S, Elliot P, McCarthy MI, Daly MJ, Järvelin MR, Freimer NB, Peltonen L. PMID: 19060910.
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    76. Efficient control of population structure in model organism association mapping. Genetics. 2008 Mar; 178(3):1709-23. Kang HM, Zaitlen NA, Wade CM, Kirby A, Heckerman D, Daly MJ, Eskin E. PMID: 18385116.
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    77. Efficient Genome Wide Tagging by Reduction to SAT. Algorithms in Bioinformatics. 2008 Jan 1; 5251:135-147. Arthur Choi, Noah Zaitlen, Buhm Han, Knot Pipatsrisawat, Adnan Darwiche, Eleazar Eskin. .
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    78. Leveraging the HapMap correlation structure in association studies. Am J Hum Genet. 2007 Apr; 80(4):683-91. Zaitlen N, Kang HM, Eskin E, Halperin E. PMID: 17357074.
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    79. Reconstructing the Phylogeny of Mobile Elements. Research in Computational Molecular Biology. 2007 Jan 1; 4453:196-210. Sean O’Rourke, Noah Zaitlen, Nebojsa Jojic, Eleazar Eskin. .
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    80. Shift-Invariant Adaptive Double Threading: Learning MHC II - Peptide Binding. Research in Computational Molecular Biology. 2007 Jan 1; 4453:181-195. Noah Zaitlen, Manuel Reyes-Gomez, David Heckerman, Nebojsa Jojic. .
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    81. Inference and analysis of haplotypes from combined genotyping studies deposited in dbSNP. Genome Res. 2005 Nov; 15(11):1594-600. Zaitlen NA, Kang HM, Feolo ML, Sherry ST, Halperin E, Eskin E. PMID: 16251470.
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