Odessa Yabut, PhD

Title(s)Assistant Professor, Neurology
SchoolSchool of Medicine
Address675 Nelson Rising Lane
San Francisco CA 94158
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    Title(s)UCSF Weill Institute for Neurosciences

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    Dr. Yabut's primary research interest is to elucidate the molecular mechanisms regulating neural stem cell behavior in stem cell niches of the developing and postnatal brain using rational mouse models. The ultimate goal of Dr. Yabut's research program is to advance our knowledge on how distinct and functional neural cell lineages are produced and facilitate the development of diagnostic and therapeutic tools to treat neurodevelopmental and neuro-oncological diseases.

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    The Role of Suppressor of Fused in Neural Stem Cells and its Implications in Tumorigenesis
    NIH K01CA201068Sep 1, 2016 - May 31, 2020
    Role: Principal Investigator
    The Significance of Regulating Shh Signaling in Cortical Progenitor Specification
    NIH F32NS087719Jun 1, 2014 - Mar 31, 2016
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Suppressor of Fused regulates the proliferation of postnatal neural stem and precursor cells via a Gli3-dependent mechanism. Biol Open. 2019 Jun 06; 8(6). Gomez HG, Noguchi H, Castillo JG, Aguilar D, Pleasure SJ, Yabut OR. PMID: 31142467.
      View in: PubMed   Mentions:
    2. Sonic Hedgehog Signaling Rises to the Surface: Emerging Roles in Neocortical Development. Brain Plast. 2018 Aug 10; 3(2):119-128. Yabut OR, Pleasure SJ. PMID: 30151337.
      View in: PubMed   Mentions:
    3. The Dorsal Wave of Neocortical Oligodendrogenesis Begins Embryonically and Requires Multiple Sources of Sonic Hedgehog. J Neurosci. 2018 06 06; 38(23):5237-5250. Winkler CC, Yabut OR, Fregoso SP, Gomez HG, Dwyer BE, Pleasure SJ, Franco SJ. PMID: 29739868.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    4. The Crossroads of Neural Stem Cell Development and Tumorigenesis. Opera Med Physiol. 2016 Dec; 2(3-4):181-187. Yabut OR, Pleasure SJ. PMID: 28795171.
      View in: PubMed   Mentions:
    5. Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors. J Dev Biol. 2016 Dec; 4(4). Yabut OR, Ng HX, Fernandez G, Yoon K, Kuhn J, Pleasure SJ. PMID: 28781964.
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    6. Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis. Cell Rep. 2015 Sep 29; 12(12):2021-34. Yabut OR, Fernandez G, Huynh T, Yoon K, Pleasure SJ. PMID: 26387942.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    7. A Notch above Sonic Hedgehog. Dev Cell. 2015 May 26; 33(4):371-2. Yabut O, Pleasure SJ, Yoon K. PMID: 26017768.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    8. The quintessence of quiescence. Neuron. 2014 May 07; 82(3):501-3. Yabut O, Pleasure SJ. PMID: 24811373.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    9. miR-125b promotes early germ layer specification through Lin28/let-7d and preferential differentiation of mesoderm in human embryonic stem cells. PLoS One. 2012; 7(4):e36121. Wong SS, Ritner C, Ramachandran S, Aurigui J, Pitt C, Chandra P, Ling VB, Yabut O, Bernstein HS. PMID: 22545159.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    10. The promise of human embryonic stem cells in aging-associated diseases. Aging (Albany NY). 2011 May; 3(5):494-508. Yabut O, Bernstein HS. PMID: 21566262.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    11. Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex. J Neurosci. 2010 Apr 14; 30(15):5219-28. Zhang J, Li H, Yabut O, Fitzpatrick H, D'Arcangelo G, Herrup K. PMID: 20392944.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    12. Dyrk1A overexpression inhibits proliferation and induces premature neuronal differentiation of neural progenitor cells. J Neurosci. 2010 Mar 17; 30(11):4004-14. Yabut O, Domogauer J, D'Arcangelo G. PMID: 20237271.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    13. The Reelin signaling pathway promotes dendritic spine development in hippocampal neurons. J Neurosci. 2008 Oct 08; 28(41):10339-48. Niu S, Yabut O, D'Arcangelo G. PMID: 18842893.
      View in: PubMed   Mentions: 99     Fields:    Translation:AnimalsCells
    14. Abnormal laminar position and dendrite development of interneurons in the reeler forebrain. Brain Res. 2007 Apr 06; 1140:75-83. Yabut O, Renfro A, Niu S, Swann JW, Marín O, D'Arcangelo G. PMID: 16996039.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
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