Olga Tymofiyeva, PhD

Title(s)Associate Professor, Radiology
SchoolSchool of Medicine
Address550 16th. Street
San Francisco CA 94158
Phone415-514-4870
ORCID ORCID Icon0000-0003-2589-1041 Additional info
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    Collapse Biography 
    Collapse Education and Training
    National Technical University of Ukraine “KPI”, UkraineB.Sc.2002Electrical Engineering
    Karlsruhe University of Applied Sciences, GermanyM.Sc. 2005Electrical Engineering
    University of Würzburg, GermanyPh.D. 2010Physics
    University of California, San Francisco, USAPostdoctoral training2014Biomedical Imaging
    University of Hagen (distant learning), GermanyB.Sc.2018Psychology
    Collapse Awards and Honors
    DAAD2003  - 2005DAAD-Siemens scholarship for Master Studies
    ESMRMB2009Young Investigator Award, 1st Place
    UCSF2011Surbeck Young Investigators Award, 2nd place
    UCSF2011Outstanding Oral Presentation Award
    UCSF2012Outstanding Poster Presentation Award
    UCSF2013Surbeck Young Investigators Award, 3rd place

    Collapse Overview 
    Collapse Overview
    Dr. Olga Tymofiyeva is an Associate Professor in the UCSF Department of Radiology and Biomedical Imaging. Dr. Tymofiyeva holds her degrees in Physics (PhD, University of Wuerzburg, Germany), Electrical Engineering (MSc, University of Applied Sciences, Karlsruhe, Germany and BSc, NTUU “KPI”, Kyiv, Ukraine), and Psychology (BSc, University of Hagen, Germany). Her main research interest is non-invasive mapping of structural and functional connectivity in the developing brain, from premature neonates to adolescents and young adults. She develops and applies advanced MRI techniques to study the neurobiological substrates of mental disorders (in particular, adolescent depression) and effects of mind-body interventions on children and adolescents. Dr. Tymofiyeva is currently the Principal Investigator for an NIH-funded study of brain plasticity in adolescents undergoing a mindfulness meditation training, the "BrainChange" study: https://radiology.ucsf.edu/research/labs/BrainChange.

    Collapse Research 
    Collapse Research Activities and Funding
    Neural mechanisms of meditation training in healthy and depressed adolescents: An MRI connectome study
    NIH R61AT009864Jul 1, 2019 - Jun 30, 2021
    Role: Principal Investigator
    A Network Approach to Study Brain Plasticity in Children with Cognitive Training
    NIH R21AT009173Dec 7, 2015 - May 31, 2019
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Featured Content 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. 2.45 Neural Correlates of Smartphone Dependence and Links to Depression in Adolescents. Journal of the American Academy of Child & Adolescent Psychiatry. 2022 Oct 1; 61(10):s197. Nguyen NB, Tymofiyeva TO, Sipes SB, Jakary JA, Freimer FD, Li LY, Yang YT. .
      View in: Publisher Site   Mentions:
    2. A Feasibility Study of a Remotely-Delivered Mindfulness-Based Training for Adolescents During the COVID-19 Pandemic. Front Psychiatry. 2022; 13:838694. Tymofiyeva O, Hu MY, Sipes BS, Jakary A, Glidden DV, Jariwala N, Bhandari S, Parks KC, Nguyen C, Henje E, Yang TT. PMID: 35633797; PMCID: PMC9133427.
      View in: PubMed   Mentions:
    3. A Domain-General Developmental "Do-GooD" Network Model of Prosocial Cognition in Adolescence: A Systematic Review. Front Behav Neurosci. 2022; 16:815811. Sipes BS, Yang TT, Parks KC, Jariwala N, Tymofiyeva O. PMID: 35350389; PMCID: PMC8957975.
      View in: PubMed   Mentions:
    4. Novel Oppositional Defiant Disorder 12 Months After Traumatic Brain Injury in Children and Adolescents. J Neuropsychiatry Clin Neurosci. 2022; 34(2):149-157. Lowet DS, Vaida F, Hesselink JR, Levin HS, Ewing-Cobbs L, Schachar RJ, Chapman SB, Bigler ED, Wilde EA, Saunders AE, Yang TT, Tymofiyeva O, Max JE. PMID: 35040660.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Neonatal brain injury influences structural connectivity and childhood functional outcomes. PLoS One. 2022; 17(1):e0262310. Ramirez A, Peyvandi S, Cox S, Gano D, Xu D, Tymofiyeva O, McQuillen PS. PMID: 34986206; PMCID: PMC8730412.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Novel Oppositional Defiant Disorder 6 Months After Traumatic Brain Injury in Children and Adolescents. J Neuropsychiatry Clin Neurosci. 2022; 34(1):68-76. Lowet DS, Kolan A, Vaida F, Hesselink JR, Levin HS, Ewing-Cobbs L, Schachar RJ, Chapman SB, Bigler ED, Wilde EA, Saunders AE, Yang TT, Tymofiyeva O, Arif H, Max JE. PMID: 34763527.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. 1.3 A Feasibility Study of a Remotely Delivered Mindfulness Training for Adolescents During the COVID-19 Pandemic. Journal of the American Academy of Child & Adolescent Psychiatry. 2021 Oct 11; 60(10):s140. Tymofiyeva TO, Hu HM, Sipes SB, Jariwala JN, Jakary JA, Nguyen NC, Parks PK, Henje HE, Yang YT. .
      View in: Publisher Site   Mentions:
    8. Traumatic Brain Injury in Children and Adolescents: Psychiatric Disorders 24 Years Later. J Neuropsychiatry Clin Neurosci. 2022; 34(1):60-67. Max JE, Troyer EA, Arif H, Vaida F, Wilde EA, Bigler ED, Hesselink JR, Yang TT, Tymofiyeva O, Wade O, Paulsen JS. PMID: 34538075.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Long-Term Psychiatric Outcomes in Adults with History of Pediatric Traumatic Brain Injury. J Neurotrauma. 2021 06 01; 38(11):1515-1525. Arif H, Troyer EA, Paulsen JS, Vaida F, Wilde EA, Bigler ED, Hesselink JR, Yang TT, Tymofiyeva O, Wade O, Max JE. PMID: 33765846; PMCID: PMC8336207.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Training-Induced Neural Plasticity in Youth: A Systematic Review of Structural and Functional MRI Studies. Front Hum Neurosci. 2020; 14:497245. Tymofiyeva O, Gaschler R. PMID: 33536885; PMCID: PMC7848153.
      View in: PubMed   Mentions: 1  
    11. Reduced anxiety and changes in amygdala network properties in adolescents with training for awareness, resilience, and action (TARA). Neuroimage Clin. 2021; 29:102521. Tymofiyeva O, Henje E, Yuan JP, Huang CY, Connolly CG, Ho TC, Bhandari S, Parks KC, Sipes BS, Yang TT, Xu D. PMID: 33316764; PMCID: PMC7735968.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    12. Neural Correlates of Smartphone Dependence in Adolescents. Front Hum Neurosci. 2020; 14:564629. Tymofiyeva O, Yuan JP, Kidambi R, Huang CY, Henje E, Rubinstein ML, Jariwala N, Max JE, Yang TT, Xu D. PMID: 33132878; PMCID: PMC7577047.
      View in: PubMed   Mentions: 4  
    13. 1.4 CHILDHOOD TRAUMA AND AMYGDALA-ORBITOFRONTAL ANATOMICAL CONNECTIVITY IN ADOLESCENTS. Journal of the American Academy of Child & Adolescent Psychiatry. 2020 Oct 1; 59(10):s140. Tymofiyeva TO, Huang HC, Bhandari BS, Lopez LE, Parks PK, Jariwala JN, Sipes SB, Yang YT. .
      View in: Publisher Site   Mentions:
    14. Gray Matter Changes in Adolescents Participating in a Meditation Training. Front Hum Neurosci. 2020; 14:319. Yuan JP, Connolly CG, Henje E, Sugrue LP, Yang TT, Xu D, Tymofiyeva O. PMID: 32922278; PMCID: PMC7456888.
      View in: PubMed   Mentions: 3  
    15. MRI Insights Into Adolescent Neurocircuitry-A Vision for the Future. Front Hum Neurosci. 2020; 14:237. Tymofiyeva O, Zhou VX, Lee CM, Xu D, Hess CP, Yang TT. PMID: 32733218; PMCID: PMC7359264.
      View in: PubMed   Mentions:
    16. 4.32 SMARTPHONE DEPENDENCE, BRAIN CONNECTIVITY, AND LINKS TO DEPRESSION IN ADOLESCENTS. Journal of the American Academy of Child & Adolescent Psychiatry. 2019 Oct 1; 58(10):s229-s230. Tymofiyeva TO, Yuan YJ, Kidambi KR, Huang HC, Blom BE, Rubinstein RM, Xu XD, Yang YT. .
      View in: Publisher Site   Mentions:
    17. Application of machine learning to structural connectome to predict symptom reduction in depressed adolescents with cognitive behavioral therapy (CBT). Neuroimage Clin. 2019; 23:101914. Tymofiyeva O, Yuan JP, Huang CY, Connolly CG, Henje Blom E, Xu D, Yang TT. PMID: 31491813; PMCID: PMC6627980.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. MEDU-15. STRUCTURAL BRAIN NETWORK PROPERTIES AND COGNITIVE IMPAIRMENT IN ADOLESCENTS AFTER RADIATION THERAPY. Neuro-Oncology. 2019 Apr 23; 21(Supplement_2):ii106-ii106. Yuan YJ, Morrison MM, Jakary JA, Mueller MS, Tymofiyeva TO, Xu XD, Lupo LJ. .
      View in: Publisher Site   Mentions:
    19. Test-Retest Reliability of Graph Theoretic Metrics in Adolescent Brains. Brain Connect. 2019 03; 9(2):144-154. Yuan JP, Henje Blom E, Flynn T, Chen Y, Ho TC, Connolly CG, Dumont Walter RA, Yang TT, Xu D, Tymofiyeva O. PMID: 30398373; PMCID: PMC6444894.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    20. Aberrant Structural Brain Connectivity in Adolescents with Attentional Problems Who Were Born Prematurely. AJNR Am J Neuroradiol. 2018 11; 39(11):2140-2147. Tymofiyeva O, Gano D, Trevino RJ, Glass HC, Flynn T, Lundy SM, McQuillen PS, Ferriero DM, Barkovich AJ, Xu D. PMID: 30337433; PMCID: PMC6239964.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    21. 5.48 Using MRI to Predict Depression Symptom Improvement in Depressed Adolescents Undergoing Cbt. Journal of the American Academy of Child & Adolescent Psychiatry. 2018 Oct 1; 57(10):s242. Tymofiyeva TO, Yuan YJ, Connolly CC, Blom BE, Xu XD, Yang YT. .
      View in: Publisher Site   Mentions:
    22. An exploratory examination of reappraisal success in depressed adolescents: Preliminary evidence of functional differences in cognitive control brain regions. J Affect Disord. 2018 11; 240:155-164. LeWinn KZ, Strigo IA, Connolly CG, Ho TC, Tymofiyeva O, Sacchet MD, Weng HY, Blom EH, Simmons AN, Yang TT. PMID: 30071419.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    23. Session 112 Emerging Multimodal Neuroimaging Findings in LATE Life Depression. American Journal of Geriatric Psychiatry. 2018 Mar 1; 26(3):s11-s12. Nelson NJ, Mackin MS, Tosun TD, Tymofiyeva TO. .
      View in: Publisher Site   Mentions:
    24. High levels of mitochondrial DNA are associated with adolescent brain structural hypoconnectivity and increased anxiety but not depression. J Affect Disord. 2018 05; 232:283-290. Tymofiyeva O, Henje Blom E, Ho TC, Connolly CG, Lindqvist D, Wolkowitz OM, Lin J, LeWinn KZ, Sacchet MD, Han LKM, Yuan JP, Bhandari SP, Xu D, Yang TT. PMID: 29500956; PMCID: PMC5864120.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    25. High-resolution MR imaging for dental impressions: a feasibility study. Clin Oral Investig. 2018 Apr; 22(3):1209-1213. Boldt J, Rottner K, Schmitter M, Hopfgartner A, Jakob P, Richter EJ, Tymofiyeva O. PMID: 28929419.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    26. Inflexible Functional Connectivity of the Dorsal Anterior Cingulate Cortex in Adolescent Major Depressive Disorder. Neuropsychopharmacology. 2017 Nov; 42(12):2434-2445. Ho TC, Sacchet MD, Connolly CG, Margulies DS, Tymofiyeva O, Paulus MP, Simmons AN, Gotlib IH, Yang TT. PMID: 28553837; PMCID: PMC5645733.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    27. Feasibility and Preliminary Efficacy of a Novel RDoC-Based Treatment Program for Adolescent Depression: "Training for Awareness Resilience and Action" (TARA)-A Pilot Study. Front Psychiatry. 2016; 7:208. Henje Blom E, Tymofiyeva O, Chesney MA, Ho TC, Moran P, Connolly CG, Duncan LG, Baldini L, Weng HY, Acree M, Goldman V, Hecht FM, Yang TT. PMID: 28138319; PMCID: PMC5237634.
      View in: PubMed   Mentions: 9  
    28. Microstructure of the Default Mode Network in Preterm Infants. AJNR Am J Neuroradiol. 2017 Feb; 38(2):343-348. Cui J, Tymofiyeva O, Desikan R, Flynn T, Kim H, Gano D, Hess CP, Ferriero DM, Barkovich AJ, Xu D. PMID: 28059709; PMCID: PMC5309151.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    29. Resting-state functional connectivity of the amygdala and longitudinal changes in depression severity in adolescent depression. J Affect Disord. 2017 Jan 01; 207:86-94. Connolly CG, Ho TC, Blom EH, LeWinn KZ, Sacchet MD, Tymofiyeva O, Simmons AN, Yang TT. PMID: 27716542; PMCID: PMC5149416.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    30. DTI-based connectome analysis of adolescents with major depressive disorder reveals hypoconnectivity of the right caudate. J Affect Disord. 2017 Jan 01; 207:18-25. Tymofiyeva O, Connolly CG, Ho TC, Sacchet MD, Henje Blom E, LeWinn KZ, Xu D, Yang TT. PMID: 27673479; PMCID: PMC5107159.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    31. Large-Scale Hypoconnectivity Between Resting-State Functional Networks in Unmedicated Adolescent Major Depressive Disorder. Neuropsychopharmacology. 2016 11; 41(12):2951-2960. Sacchet MD, Ho TC, Connolly CG, Tymofiyeva O, Lewinn KZ, Han LK, Blom EH, Tapert SF, Max JE, Frank GK, Paulus MP, Simmons AN, Gotlib IH, Yang TT. PMID: 27238621; PMCID: PMC5061890.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    32. The neuroscience and context of adolescent depression. Acta Paediatr. 2016 Apr; 105(4):358-65. Henje Blom E, Ho TC, Connolly CG, LeWinn KZ, Sacchet MD, Tymofiyeva O, Weng HY, Yang TT. PMID: 26663379; PMCID: PMC4779656.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    33. Effects of rejecting diffusion directions on tensor-derived parameters. Neuroimage. 2015 Apr 01; 109:160-70. Chen Y, Tymofiyeva O, Hess CP, Xu D. PMID: 25585018; PMCID: PMC4339467.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    34. Structural MRI connectome in development: challenges of the changing brain. Br J Radiol. 2014 Jul; 87(1039):20140086. Tymofiyeva O, Hess CP, Xu D, Barkovich AJ. PMID: 24827379; PMCID: PMC4075590.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    35. Brain without anatomy: construction and comparison of fully network-driven structural MRI connectomes. PLoS One. 2014; 9(5):e96196. Tymofiyeva O, Ziv E, Barkovich AJ, Hess CP, Xu D. PMID: 24789312; PMCID: PMC4006896.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    36. A machine learning approach to automated structural network analysis: application to neonatal encephalopathy. PLoS One. 2013; 8(11):e78824. Ziv E, Tymofiyeva O, Ferriero DM, Barkovich AJ, Hess CP, Xu D. PMID: 24282501; PMCID: PMC3840059.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    37. Dynamic MRI of the TMJ under physical load. Dentomaxillofac Radiol. 2013; 42(9):20120436. Hopfgartner AJ, Tymofiyeva O, Ehses P, Rottner K, Boldt J, Richter EJ, Jakob PM. PMID: 23975114; PMCID: PMC3828022.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    38. A DTI-based template-free cortical connectome study of brain maturation. PLoS One. 2013; 8(5):e63310. Tymofiyeva O, Hess CP, Ziv E, Lee PN, Glass HC, Ferriero DM, Barkovich AJ, Xu D. PMID: 23675475; PMCID: PMC3652871.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    39. Influence of dental materials on dental MRI. Dentomaxillofac Radiol. 2013; 42(6):20120271. Tymofiyeva O, Vaegler S, Rottner K, Boldt J, Hopfgartner AJ, Proff PC, Richter EJ, Jakob PM. PMID: 23610088; PMCID: PMC3667526.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    40. Diagnosis of dental abnormalities in children using 3-dimensional magnetic resonance imaging. J Oral Maxillofac Surg. 2013 Jul; 71(7):1159-69. Tymofiyeva O, Proff PC, Rottner K, Düring M, Jakob PM, Richter EJ. PMID: 23611603.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    41. Towards the "baby connectome": mapping the structural connectivity of the newborn brain. PLoS One. 2012; 7(2):e31029. Tymofiyeva O, Hess CP, Ziv E, Tian N, Bonifacio SL, McQuillen PS, Ferriero DM, Barkovich AJ, Xu D. PMID: 22347423; PMCID: PMC3274551.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    42. On precise localization of boundaries between extended uniform objects in MRI: tooth imaging as an example. MAGMA. 2011 Feb; 24(1):19-28. Tymofiyeva O, Schmid F, von Kienlin M, Breuer FA, Rottner K, Boldt J, Richter EJ, Jakob PM. PMID: 20878537.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    43. High-resolution 3D magnetic resonance imaging and quantification of carious lesions and dental pulp in vivo. MAGMA. 2009 Dec; 22(6):365-74. Tymofiyeva O, Boldt J, Rottner K, Schmid F, Richter EJ, Jakob PM. PMID: 19924456.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    44. Three-dimensional localization of impacted teeth using magnetic resonance imaging. Clin Oral Investig. 2010 Apr; 14(2):169-76. Tymofiyeva O, Rottner K, Jakob PM, Richter EJ, Proff P. PMID: 19399539.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    45. In Vivo 3D Imaging of Carious Lesions and Dental Pulp Using Magnetic Resonance. World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany. 2009 Jan 1; 25/11:216-218. Tymofiyeva TO, Rottner RK, Boldt BJ, Schmid SF, Richter RE, Jakob JP. .
      View in: Publisher Site   Mentions:
    46. In vivo MRI-based dental impression using an intraoral RF receiver coil. Concepts in Magnetic Resonance Part B. 2008 Oct 1; 33B(4):244-251. Tymofiyeva TO, Rottner RK, Gareis GD, Boldt BJ, Schmid SF, Lopez LM, Richter RE, Jakob JP. .
      View in: Publisher Site   Mentions:
    47. In vivo MRI-based dental impression using an intraoral RF receiver coil. Concept Magn Reson B: Magn Reson Eng. 2008; (33B):244-251. Tymofiyeva O, Rottner K, Gareis D, Boldt J, Schmid F, Lopez MA, Richter E-J, Jakob PM. View Publication.
    48. Correlation of MRT imaging with real-time axiography of TMJ clicks. Ann Anat. 2007; 189(4):356-61. Tymofiyeva O, Proff P, Richter EJ, Jakob P, Fanghänel J, Gedrange T, Rottner K. PMID: 17695992.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
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