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Ophelia Yin, MD

Photo of Ophelia Yin, MD
Title(s)Assistant Professor, Ob/Gyn, Reproductive Sciences
SchoolSchool of Medicine
Address490 Illinois Street, #102N
San Francisco CA 94158
ORCID ORCID Icon0000-0002-1933-2262 Additional info
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    Collapse Biography 
    Collapse education and training
    Princeton UniversityB.A.2013Major: Ecology and Evolutionary Biology Minors: Bioengineering, Global Health & Health Policy
    Johns Hopkins University School of MedicineM.D.2018Medicine
    UCLA, Los AngelesResidency2022Obstetrics and Gynecology
    UCSF, San FranciscoFellowship2025Maternal-Fetal Medicine
    Collapse awards and honors
    Perinatal Research Society2024  - 2024NIH Young Investigator Trainee Award
    University of California, Los Angeles2022  - 2022Outstanding Resident Research Award
    Alpha Omega Alpha2018  - 2018Medical Honor Society Award
    American College of Obstetricians and Gynecologists2014  - 2014District IV Gibbon's Award for Conference Funding
    Johns Hopkins2014  - 2014Dean's Funding for Scholarly Summer Research
    Asian Pacific American Medical Student Association2014  - 2014Distinguished Chapter Award
    Johns Hopkins2014  - 2014Student Outreach Resource Center Award
    Sigma Xi National Honor Society 2013  - 2013Scientific Research Award
    Princeton University2013  - 2013Magna Cum Laude

    Collapse Overview 
    Collapse overview
    Dr. Ophelia Yin is a perinatologist, an obstetrician who specializes in high-risk pregnancies. As an expert in maternal-fetal medicine, she makes prenatal diagnoses of disorders or complications and performs ultrasounds. She has notable expertise in caring for pregnant people who have had a solid organ transplant (including kidney, liver, heart, lung, pancreas, dual-organ and uterine transplants), helping them navigate the preconception, pregnancy and postpartum periods. In collaboration with neurologists, she supports pregnant patients affected by neurological conditions, such as multiple sclerosis, myasthenia gravis, epilepsy, stroke, vascular malformations, aneurysms, and other brain or spine problems. Her experience encompasses managing severe cases of placental disorders, including preeclampsia, and pregnancy-impacting autoimmune disease.

    In her research, Yin works with the Transplant Pregnancy Registry International to advance care for transplant patients using a team-based approach. With the UCSF March of Dimes Prematurity Research Center, she investigates how the immune system contributes to complications in pregnancy and conducts translational studies – which apply lab findings to real-world patient care – focused on preeclampsia, placental abnormalities and preterm birth. She has been a scholar in the Chan Zuckerberg Biohub Physician-Scientist Program.

    At Princeton University, Yin earned an undergraduate degree in ecology and evolutionary biology, with concentrations in bioengineering and in global health and health policy. She earned her medical degree at the Johns Hopkins University School of Medicine, where she was elected to the Alpha Omega Alpha Honor Medical Society. She completed a residency in obstetrics and gynecology at the University of California, Los Angeles, where she served as administrative chief resident, followed by a fellowship in maternal-fetal medicine at UCSF. During her medical training, she earned awards for community service, teaching, research and patient care. She is active in multiple national medical societies, including the Society for Maternal-Fetal Medicine, Society for Reproductive Investigation and American Society of Transplantation.

    Yin grew up in Southern California and loves being back in her home state. Outside of work, she enjoys spending time with her husband, cats, family and friends. She loves nature, reading, traveling, and trying new foods and experiences in San Francisco.
    Collapse Mentoring
    Collapse Community and Public Service

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Transcriptomic comparison of early onset preeclampsia and placenta accreta identifies inverse trophoblast and decidua functions at the maternal-fetal interface. bioRxiv. 2025 May 14. Yin O, Almonte-Loya A, Appierdo R, Yang M, Yilmaz BD, Oskotsky TT, Gonzalez JM, Giudice LC, Afshar Y, Sirota M. PMID: 40463057; PMCID: PMC12132514.
      View in: PubMed   Mentions:
    2. Updates and Knowledge Gaps in Placenta Accreta Spectrum Biology. Clin Obstet Gynecol. 2025 Jun 01; 68(2):310-316. Kashani-Ligumsky L, Scott O, Martinez G, Jeong A, Yin O, Shah S, Wang A, Zhu Y, Afshar Y. PMID: 40257851.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Heart Transplant and Pregnancy: Evaluating the Role of Preeclampsia in Maternal, Neonatal, and Graft Morbidity. JACC Heart Fail. 2025 Mar; 13(3):498-507. Kirschner V, Yin O, Coscia L, Diala PC, Shahandeh N, Irani RA, Constantinescu S, Moritz MJ, Afshar Y. PMID: 40044385.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Safety of a trial of labor after cesarean in kidney and liver transplant recipients: A multicenter cohort study. Int J Gynaecol Obstet. 2025 Jul; 170(1):471-477. Walia A, Yin O, Coscia LA, Constantinescu S, Sarkar M, Moritz MJ, Afshar Y, Irani RA. PMID: 39968735; PMCID: PMC12177271.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Pre-conception clinical risk factors differ between spontaneous and indicated preterm birth in a densely phenotyped EHR cohort. BMC Pregnancy Childbirth. 2025 Feb 12; 25(1):149. Costello JM, Takasuka H, Roger J, Yin O, Tang A, Oskotsky T, Sirota M, Capra JA. PMID: 39939846; PMCID: PMC11817080.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Clinical outcomes in patients with unintended pregnancy after liver transplantation: A multicenter registry cohort study. Liver Transpl. 2025 Jul 01; 31(7):916-923. Walia A, Yin O, Coscia L, Afshar Y, Irani R, Constantinescu S, Moritz M, Sarkar M. PMID: 39451110.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Differences in neonatal sepsis among immunosuppression regimens in pregnancies of transplant recipients. Am J Obstet Gynecol MFM. 2024 Nov; 6(11):101482. Pithia N, Yin O, Coscia LA, Constantinescu S, Moritz MJ, Afshar Y. PMID: 39260770.
      View in: PubMed   Mentions:    Fields:    
    8. Data-driven insights can transform women's reproductive health. NPJ Womens Health. 2024; 2(1):14. Oskotsky TT, Yin O, Khan U, Arnaout L, Sirota M. PMID: 38770215; PMCID: PMC11104016.
      View in: PubMed   Mentions: 2  
    9. Placenta accreta spectrum disorder at single-cell resolution: a loss of boundary limits in the decidua and endothelium. Am J Obstet Gynecol. 2024 04; 230(4):443.e1-443.e18. Afshar Y, Yin O, Jeong A, Martinez G, Kim J, Ma F, Jang C, Tabatabaei S, You S, Tseng HR, Zhu Y, Krakow D. PMID: 38296740.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    10. Associations with spontaneous and indicated preterm birth in a densely phenotyped EHR cohort. medRxiv. 2023 Nov 30. Costello JM, Takasuka H, Roger J, Yin O, Tang A, Oskotsky T, Sirota M, Capra JA. PMID: 38077057; PMCID: PMC10705634.
      View in: PubMed   Mentions:
    11. Pregnancy after deceased donor vs living donor kidney transplant: associated obstetric and graft outcomes. Am J Obstet Gynecol. 2024 02; 230(2):256.e1-256.e12. Yin O, Coscia L, Constantinescu S, Moritz MJ, Afshar Y, Irani RA. PMID: 37595824.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Emergent prelabor cesarean delivery in solid organ transplant recipients: associated risk factors and outcomes. Am J Obstet Gynecol MFM. 2023 02; 5(2):100799. Chung K, Yin O, Kallapur A, Bass L, Coscia L, Constantinescu S, Moritz M, Afshar Y. PMID: 36368514.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. The role of Hippo pathway signaling and A-kinase anchoring protein 13 in primordial follicle activation and inhibition. F S Sci. 2022 05; 3(2):118-129. Maher JY, Islam MS, Yin O, Brennan J, Gough E, Driggers P, Segars J. PMID: 35560009; PMCID: PMC11096729.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    14. Extracorporeal membrane oxygenation in pregnancy: details on novel therapies and cardiac, preeclampsia, and mood disorder complications. Am J Obstet Gynecol. 2022 06; 226(6):873-874. Yin O, Richley M, Afshar Y. PMID: 35065020; PMCID: PMC8824254.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Extracorporeal membrane oxygenation in pregnancy: a bridge to delivery and pulmonary recovery for COVID-19-related severe respiratory failure. Am J Obstet Gynecol. 2022 04; 226(4):571-576.e5. Yin O, Richley M, Hadaya J, Mei J, Mok T, Fahim M, Pluym ID, Rao R, Martin C, Han CS, Benharash P, Afshar Y. PMID: 34922925; PMCID: PMC8675182.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    16. Mode of Obstetric Delivery in Kidney and Liver Transplant Recipients and Associated Maternal, Neonatal, and Graft Morbidity During 5 Decades of Clinical Practice. JAMA Netw Open. 2021 10 01; 4(10):e2127378. Yin O, Kallapur A, Coscia L, Kwan L, Tandel M, Constantinescu SA, Moritz MJ, Afshar Y. PMID: 34605918; PMCID: PMC8491100.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    17. Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders. Nat Commun. 2021 08 03; 12(1):4408. Afshar Y, Dong J, Zhao P, Li L, Wang S, Zhang RY, Zhang C, Yin O, Han CS, Einerson BD, Gonzalez TL, Zhang H, Zhou A, Yang Z, Chou SJ, Sun N, Cheng J, Zhu H, Wang J, Zhang TX, Lee YT, Wang JJ, Teng PC, Yang P, Qi D, Zhao M, Sim MS, Zhe R, Goldstein JD, Williams J, Wang X, Zhang Q, Platt LD, Zou C, Pisarska MD, Tseng HR, Zhu Y. PMID: 34344888; PMCID: PMC8333096.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    18. Pregnancy care in solid organ transplant recipients. Int J Gynaecol Obstet. 2022 Jun; 157(3):502-513. Kallapur A, Jang C, Yin O, Mei JY, Afshar Y. PMID: 34245162.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    19. Differentiating Acute Rejection From Preeclampsia After Kidney Transplantation. Obstet Gynecol. 2021 06 01; 137(6):1023-1031. Yin O, Kallapur A, Coscia L, Constantinescu S, Moritz M, Afshar Y. PMID: 33957644; PMCID: PMC8141043.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. Discordant congenital heart defects in monochorionic twins: Risk factors and proposed pathophysiology. PLoS One. 2021; 16(5):e0251160. Imany-Shakibai H, Yin O, Russell MR, Sklansky M, Satou G, Afshar Y. PMID: 33956871; PMCID: PMC8101911.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    21. Maternal Central Blood Pressure Is Associated with Fetal Middle Cerebral Artery Dopplers. Reprod Sci. 2020 02; 27(2):655-661. Woods A, Afshar Y, Yin O, Jones WM, Kwan L, Zhang H, Koos BJ, DeVore G. PMID: 32046428.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Central hemodynamics are associated with fetal outcomes in pregnancies of advanced maternal age. Pregnancy Hypertens. 2020 Jan; 19:67-73. Yin O, Woods A, Koos B, DeVore G, Afshar Y. PMID: 31923879.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    23. Edoxaban Versus Warfarin in Patients With Atrial Fibrillation and History of Liver Disease. J Am Coll Cardiol. 2019 07 16; 74(2):179-189. Qamar A, Antman EM, Ruff CT, Nordio F, Murphy SA, Grip LT, Greenberger NJ, Yin OQP, Choi Y, Lanz HJ, Mercuri MF, Braunwald E, Giugliano RP. PMID: 31296289.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    24. Association between polycystic ovary syndrome and hot flash presentation during the midlife period. Menopause. 2018 06; 25(6):691-696. Yin O, Zacur HA, Flaws JA, Christianson MS. PMID: 29360703.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. Lesbian, gay, bisexual, transgender content on reproductive endocrinology and infertility clinic websites. Fertil Steril. 2017 07; 108(1):183-191. Wu HY, Yin O, Monseur B, Selter J, Collins LJ, Lau BD, Christianson MS. PMID: 28579417.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    26. Hysteroscopic polypectomy prior to infertility treatment: A cost analysis and systematic review. Eur J Obstet Gynecol Reprod Biol. 2017 Jun; 213:107-115. Mouhayar Y, Yin O, Mumford SL, Segars JH. PMID: 28445799; PMCID: PMC5505524.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    27. In Vitro Activation: A Dip Into the Primordial Follicle Pool? J Clin Endocrinol Metab. 2016 10; 101(10):3568-3570. Yin O, Cayton K, Segars JH. PMID: 27702318.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    28. The Student Curriculum Review Team: How we catalyze curricular changes through a student-centered approach. Med Teach. 2015; 37(11):1008-12. Hsih KW, Iscoe MS, Lupton JR, Mains TE, Nayar SK, Orlando MS, Parzuchowski AS, Sabbagh MF, Schulz JC, Shenderov K, Simkin DJ, Vakili S, Vick JB, Xu T, Yin O, Goldberg HR. PMID: 25532595.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
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