Ozgur Genc, PhD

Title(s)Specialist, Biochemistry and Biophysics
SchoolSchool of Medicine
Address1550 4th Street, Bldg 19B
San Francisco CA 94158
ORCID ORCID Icon0000-0003-0635-3192 Additional info
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    The brain contains billions of neurons and undergoes changes throughout the life. Despite its complex and plastic nature, it has a remarkable capacity to maintain its stable function. My broad research interest is to understand how the nervous system achieves stable levels of activity during the lifetime of an organism.

    I employ genome-wide screening approaches in fruit flies to identify mutations that create risk for disease and test how they affect neuronal physiology in rodent and iPSC models by employing electrophysiological, optical and transcriptional methods.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Homeostatic plasticity fails at the intersection of autism-gene mutations and a novel class of common genetic modifiers. Elife. 2020 07 01; 9. Genç Ö, An JY, Fetter RD, Kulik Y, Zunino G, Sanders SJ, Davis GW. PMID: 32609087.
      View in: PubMed   Mentions:    Fields:    
    2. Target-wide Induction and Synapse Type-Specific Robustness of Presynaptic Homeostasis. Curr Biol. 2019 11 18; 29(22):3863-3873.e2. Genç Ö, Davis GW. PMID: 31708391.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. Molecular mechanisms that stabilize short term synaptic plasticity during presynaptic homeostatic plasticity. Elife. 2018 11 13; 7. Ortega JM, Genç Ö, Davis GW. PMID: 30422113.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    4. MCTP is an ER-resident calcium sensor that stabilizes synaptic transmission and homeostatic plasticity. Elife. 2017 05 09; 6. Genç Ö, Dickman DK, Ma W, Tong A, Fetter RD, Davis GW. PMID: 28485711.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    5. RIM-binding protein links synaptic homeostasis to the stabilization and replenishment of high release probability vesicles. Neuron. 2015 Mar 04; 85(5):1056-69. PMID: 25704950.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    6. Munc18-1 is a dynamically regulated PKC target during short-term enhancement of transmitter release. Elife. 2014 Feb 11; 3:e01715. PMID: 24520164.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    7. Nigrostriatal overabundance of a-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity. Acta Neuropathol. 2012 May; 123(5):653-69. PMID: 22361813.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
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