Loading...

Paul Larson, MD

Title(s)Professor, Neurological Surgery
SchoolSchool of Medicine
Address505 Parnassus Avenue
San Francisco CA 94117
Phone415-502-2885
vCardDownload vCard
    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    University of Arizona, Tucson, AZ1995MD
    University of Louisville, Louisville, KY2001Neurosurgery Residency

    Collapse Overview 
    Collapse Overview
    Dr. Paul Larson is Professor and Vice Chair of Neurological Surgery at the University of California San Francisco, Chief of Neurosurgery at the San Francisco VA Medical Center and Surgical Director of the Parkinson’s Disease Research, Education and Clinical Center. He specializes in functional neurosurgery, specifically deep brain stimulation for movement disorders and MR-guided procedures. The Surgical Movement Disorders program at UCSF and the SFVA is one of the largest and most active centers in the world.

    Dr. Larson’s research program is built around three core areas of interest. He has 20 years of experience in interventional MRI-guided surgery, and was one of three researchers at UCSF that started and developed the field of iMRI-guided stereotactic surgery for DBS placement and drug delivery. He has had continuous funding for device development and clinical trials in interventional MRI procedures since 2003. Secondly, his group at UCSF has been at the forefront of gene therapy for Parkinson’s disease. They have had a leadership role in 4 of the 7 human trials completed worldwide to date, and have performed more than 1/3 of all Parkinson’s gene therapy procedures ever performed. He is currently the PI for a fifth gene therapy trial using convection enhanced, iMRI-guided delivery of AAV2-AADC into the putamen of patients with Parkinson’s disease. Finally, Dr. Larson has a significant interest in the neurobiology and underlying brain circuitry of phantom auditory disorders including tinnitus. His work in this area with Dr. Steven Cheung has led to the discovery of a new region of brain involved in auditory perception, as well as a new proposed model of the basal ganglia for chronic tinnitus. They have a U01 grant from the NIDCD to study the use of DBS in the caudate nucleus in patients with severe, medically refractory tinnitus.

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites
    Collapse Student Projects
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Data-driven evolution of neurosurgical gene therapy delivery in Parkinson's disease. J Neurol Neurosurg Psychiatry. 2020 Jul 30. Richardson RM, Bankiewicz KS, Christine CW, Van Laar AD, Gross RE, Lonser R, Factor SA, Kostyk SK, Kells AP, Ravina B, Larson PS. PMID: 32732384.
      View in: PubMed   Mentions:    Fields:    
    2. Rescue Ventral Intermediate Thalamus Deep Brain Stimulation to Address Refractory Tremor Following Subthalamic Nucleus Deep Brain Stimulation With Brittle Dyskinesia. . 2020 Jun 1; 115-118. Mitra Afshari, Jill L. Ostrem, Marta San Luciano, Paul S. Larson. .
      View in: Publisher Site   Mentions:
    3. Aromatic L-Amino Acid Decarboxylase Gene Therapy Enhances Levodopa Response in Parkinson's Disease. Mov Disord. 2020 05; 35(5):851-858. Nutt JG, Curtze C, Hiller A, Anderson S, Larson PS, Van Laar AD, Richardson RM, Thompson ME, Sedkov A, Leinonen M, Ravina B, Bankiewicz KS, Christine CW. PMID: 32149427.
      View in: PubMed   Mentions:    Fields:    
    4. Prefrontal-Subthalamic Hyperdirect Pathway Modulates Movement Inhibition in Humans. Neuron. 2020 05 20; 106(4):579-588.e3. Chen W, de Hemptinne C, Miller AM, Leibbrand M, Little SJ, Lim DA, Larson PS, Starr PA. PMID: 32155442.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Accounting for Deformation in Deep Brain Stimulation Surgery With Models: Comparison to Interventional Magnetic Resonance Imaging. IEEE Trans Biomed Eng. 2020 Oct; 67(10):2934-2944. Luo M, Larson PS, Martin AJ, Miga MI. PMID: 32078527.
      View in: PubMed   Mentions:    Fields:    
    6. Phase I trial of caudate deep brain stimulation for treatment-resistant tinnitus. J Neurosurg. 2019 Sep 24; 1-10. Cheung SW, Racine CA, Henderson-Sabes J, Demopoulos C, Molinaro AM, Heath S, Nagarajan SS, Bourne AL, Rietcheck JE, Wang SS, Larson PS. PMID: 31553940.
      View in: PubMed   Mentions:    Fields:    
    7. Altered Prefrontal Theta and Gamma Activity during an Emotional Face Processing Task in Parkinson Disease. J Cogn Neurosci. 2019 11; 31(11):1768-1776. Chen W, de Hemptinne C, Leibbrand M, Miller AM, Larson PS, Starr PA. PMID: 31322465.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Magnetic resonance imaging-guided phase 1 trial of putaminal AADC gene therapy for Parkinson's disease. Ann Neurol. 2019 05; 85(5):704-714. Christine CW, Bankiewicz KS, Van Laar AD, Richardson RM, Ravina B, Kells AP, Boot B, Martin AJ, Nutt J, Thompson ME, Larson PS. PMID: 30802998.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    9. Human caudate nucleus subdivisions in tinnitus modulation. J Neurosurg. 2019 Feb 08; 1-7. Perez PL, Wang SS, Heath S, Henderson-Sabes J, Mizuiri D, Hinkley LB, Nagarajan SS, Larson PS, Cheung SW. PMID: 30738400.
      View in: PubMed   Mentions: 2     Fields:    
    10. Chapter 23 Direct Convective Nervous System Drug Delivery for Patients with Neurodegenerative Disorders. Nervous System Drug Delivery. 2019 Jan 1; 463-472. R. Mark Richardson, Paul Larson. .
      View in: Publisher Site   Mentions:
    11. An Integrated Multi-physics Finite Element Modeling Framework for Deep Brain Stimulation: Preliminary Study on Impact of Brain Shift on Neuronal Pathways. . 2019 Jan 1; 11768:682-690. Ma Luo, Paul S. Larson, Alastair J. Martin, Peter E. Konrad, Michael I. Miga. .
      View in: Publisher Site   Mentions:
    12. Surgical management of camptocormia in Parkinson's disease: systematic review and meta-analysis. J Neurosurg. 2018 09 14; 131(2):368-375. Chan AK, Chan AY, Lau D, Durcanova B, Miller CA, Larson PS, Starr PA, Mummaneni PV. PMID: 30215560.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Accuracy of image-guided percutaneous injection into a phantom spinal cord utilizing flat panel detector CT with MR fusion and integrated navigational software. J Neurointerv Surg. 2018 Dec; 10(12):e37. Talbott JF, Cooke DL, Mabray MC, Larson PS, Amans MR, Hetts SW, Wilson MW, Moore T, Salegio EA. PMID: 29666181.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    14. Venous Thromboembolism during Interventional MRI-Guided Stereotactic Surgery. Stereotact Funct Neurosurg. 2018; 96(1):40-45. Kundishora AJ, Englot DJ, Starr PA, Martin AJ, Larson PS. PMID: 29495014.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Laser ablative therapy of sessile hypothalamic hamartomas in children using interventional MRI: report of 5 cases. J Neurosurg Pediatr. 2018 05; 21(5):460-465. Southwell DG, Birk HS, Larson PS, Starr PA, Sugrue LP, Auguste KI. PMID: 29451455.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Deep Brain Stimulation: Interventional and Intraoperative MRI Approaches. Prog Neurol Surg. 2018; 33:187-197. Larson PS, Starr PA, Martin AJ. PMID: 29332083.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Before and after the veterans affairs cooperative program 468 study: Deep brain stimulator target selection for treatment of Parkinson's disease. Parkinsonism Relat Disord. 2018 03; 48:40-44. Southwell DG, Rutkowski MJ, San Luciano M, Racine C, Ostrem J, Starr PA, Larson PS. PMID: 29249683.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Hemorrhage Detection and Incidence during Magnetic Resonance-Guided Deep Brain Stimulator Implantations. Stereotact Funct Neurosurg. 2017; 95(5):307-314. Martin AJ, Starr PA, Ostrem JL, Larson PS. PMID: 28889128.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Little Black Boxes: Noncardiac Implantable Electronic Medical Devices and Their Anesthetic and Surgical Implications. Anesth Analg. 2017 07; 125(1):124-138. Srejic U, Larson P, Bickler PE. PMID: 28489640.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. MRI-guided stereotactic neurosurgical procedures in a diagnostic MRI suite: Background and safe practice recommendations. J Healthc Risk Manag. 2017 Jul; 37(1):31-39. Larson PS, Willie JT, Vadivelu S, Azmi-Ghadimi H, Nichols A, Fauerbach LL, Johnson HB, Graham D. PMID: 28719087.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    21. Parkinson's disease patient preference and experience with various methods of DBS lead placement. Parkinsonism Relat Disord. 2017 Aug; 41:25-30. LaHue SC, Ostrem JL, Galifianakis NB, San Luciano M, Ziman N, Wang S, Racine CA, Starr PA, Larson PS, Katz M. PMID: 28615151.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    22. Neurosurgical laser ablation and MR thermometry: Risks of multisite workflow pattern. J Healthc Risk Manag. 2017 Apr; 36(4):7-18. Larson PS, Vadivelu S, Azmi-Ghadimi H, Nichols A, Fauerbach L, Johnson HB. PMID: 28415147.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Thalamic DBS with a constant-current device in essential tremor: A controlled clinical trial. Parkinsonism Relat Disord. 2017 Jul; 40:18-26. Wharen RE, Okun MS, Guthrie BL, Uitti RJ, Larson P, Foote K, Walker H, Marshall FJ, Schwalb J, Ford B, Jankovic J, Simpson R, Dashtipour K, Phibbs F, Neimat JS, Stewart RM, Peichel D, Pahwa R, Ostrem JL. PMID: 28400200.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    24. An unexpectedly high rate of revisions and removals in deep brain stimulation surgery: Analysis of multiple databases. Parkinsonism Relat Disord. 2016 12; 33:72-77. Rolston JD, Englot DJ, Starr PA, Larson PS. PMID: 27645504.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    25. Spinal Subdural Abscess Following Laminectomy for Symptomatic Stenosis: A Report of 2 Cases and Review of the Literature. Am J Case Rep. 2016 Jul 12; 17:476-83. Ramos AD, Rolston JD, Gauger GE, Larson PS. PMID: 27402228.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    26. Interventional MRI-guided catheter placement and real time drug delivery to the central nervous system. Expert Rev Neurother. 2016 06; 16(6):635-9. Han SJ, Bankiewicz K, Butowski NA, Larson PS, Aghi MK. PMID: 27054877.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    27. Comparison of Deep Brain Stimulation Lead Targeting Accuracy and Procedure Duration between 1.5- and 3-Tesla Interventional Magnetic Resonance Imaging Systems: An Initial 12-Month Experience. Stereotact Funct Neurosurg. 2016; 94(2):102-7. Southwell DG, Narvid JA, Martin AJ, Qasim SE, Starr PA, Larson PS. PMID: 27093443.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    28. Deep brain stimulator implantation in a diagnostic MRI suite: infection history over a 10-year period. J Neurosurg. 2017 Jan; 126(1):108-113. Martin AJ, Larson PS, Ziman N, Levesque N, Volz M, Ostrem JL, Starr PA. PMID: 27015399.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    29. Long-Term Safety of Patients with Parkinson's Disease Receiving rAAV2-Neurturin (CERE-120) Gene Transfer. Hum Gene Ther. 2016 07; 27(7):522-7. Marks WJ, Baumann TL, Bartus RT. PMID: 26711317.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCellsCTClinical Trials
    30. Merging DBS with viral vector or stem cell implantation: "hybrid" stereotactic surgery as an evolution in the surgical treatment of Parkinson's disease. Mol Ther Methods Clin Dev. 2016; 3:15051. Rowland NC, Kalia SK, Kalia LV, Larson PS, Lim DA, Bankiewicz KS. PMID: 26817024.
      View in: PubMed   Mentions:
    31. Clinical outcomes using ClearPoint interventional MRI for deep brain stimulation lead placement in Parkinson's disease. J Neurosurg. 2016 Apr; 124(4):908-16. Ostrem JL, Ziman N, Galifianakis NB, Starr PA, Luciano MS, Katz M, Racine CA, Martin AJ, Markun LC, Larson PS. PMID: 26495947.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    32. E-053 accuracy of flat panel detector ct with integrated navigational software with and without mr fusion for single pass needle placement in a deep brain stimulator phantom in the interventional suite. Journal of NeuroInterventional Surgery. 2015 Jul 1; 7(Suppl 1):a66.1-a66. M Mabray, S Datta, P Lillaney, T Moore, S Gehrisch, J Talbott, P Larson, D Cooke. .
      View in: Publisher Site   Mentions:
    33. Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: A double-blind, randomized, controlled trial. Ann Neurol. 2015 Aug; 78(2):248-57. Warren Olanow C, Bartus RT, Baumann TL, Factor S, Boulis N, Stacy M, Turner DA, Marks W, Larson P, Starr PA, Jankovic J, Simpson R, Watts R, Guthrie B, Poston K, Henderson JM, Stern M, Baltuch G, Goetz CG, Herzog C, Kordower JH, Alterman R, Lozano AM, Lang AE. PMID: 26061140.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    34. Accuracy of flat panel detector CT with integrated navigational software with and without MR fusion for single-pass needle placement. J Neurointerv Surg. 2016 Jul; 8(7):731-5. Mabray MC, Datta S, Lillaney PV, Moore T, Gehrisch S, Talbott JF, Levitt MR, Ghodke BV, Larson PS, Cooke DL. PMID: 26047903.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    35. Differential effects of deep brain stimulation target on motor subtypes in Parkinson's disease. Ann Neurol. 2015 Apr; 77(4):710-9. Katz M, Luciano MS, Carlson K, Luo P, Marks WJ, Larson PS, Starr PA, Follett KA, Weaver FM, Stern MB, Reda DJ, Ostrem JL. PMID: 25627340.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    36. Surgical implantation of STN-DBS leads using intraoperative MRI guidance: technique, accuracy, and clinical benefit at 1-year follow-up. Acta Neurochir (Wien). 2015 Apr; 157(4):729-37. Chabardes S, Isnard S, Castrioto A, Oddoux M, Fraix V, Carlucci L, Payen JF, Krainik A, Krack P, Larson P, Le Bas JF. PMID: 25788414.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    37. Combining cell transplants or gene therapy with deep brain stimulation for Parkinson's disease. Mov Disord. 2015 Feb; 30(2):190-5. Rowland NC, Starr PA, Larson PS, Ostrem JL, Marks WJ, Lim DA. PMID: 25521796.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    38. Delay Period Activity of the Substantia Nigra during Proactive Control of Response Selection as Determined by a Novel fMRI Localization Method. J Cogn Neurosci. 2015 Jun; 27(6):1238-48. Yoon JH, Larson P, Grandelis A, La C, Cui E, Carter CS, Minzenberg MJ. PMID: 25514657.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. Neuropsychological changes following deep brain stimulation surgery for Parkinson's disease: comparisons of treatment at pallidal and subthalamic targets versus best medical therapy. J Neurol Neurosurg Psychiatry. 2015 Jun; 86(6):622-9. Rothlind JC, York MK, Carlson K, Luo P, Marks WJ, Weaver FM, Stern M, Follett K, Reda D. PMID: 25185211.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    40. Interventional magnetic resonance imaging-guided cell transplantation into the brain with radially branched deployment. Mol Ther. 2015 Jan; 23(1):119-29. Silvestrini MT, Yin D, Martin AJ, Coppes VG, Mann P, Larson PS, Starr PA, Zeng X, Gupta N, Panter SS, Desai TA, Lim DA. PMID: 25138755.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    41. Interventional MRI-guided deep brain stimulation in pediatric dystonia: first experience with the ClearPoint system. J Neurosurg Pediatr. 2014 Oct; 14(4):400-8. Starr PA, Markun LC, Larson PS, Volz MM, Martin AJ, Ostrem JL. PMID: 25084088.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    42. Deep brain stimulation for movement disorders. Neurotherapeutics. 2014 Jul; 11(3):465-74. Larson PS. PMID: 24833244.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    43. Brain shift during bur hole-based procedures using interventional MRI. J Neurosurg. 2014 Jul; 121(1):149-60. Ivan ME, Yarlagadda J, Saxena AP, Martin AJ, Starr PA, Sootsman WK, Larson PS. PMID: 24785326.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    44. Image-guided deep brain stimulation. Neurosurg Clin N Am. 2014 Jan; 25(1):159-72. Vega RA, Holloway KL, Larson PS. PMID: 24262907.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    45. 203 Application Accuracy of a Second Generation Interventional MRI Stereotactic Platform. Neurosurgery. 2013 Aug 1; 60(&NA;):187. Paul Larson, Philip A. Starr, Jill L. Ostrem, Nicholas Galifianakis, Marta San Luciano Palenzuela, Alastair Martin. .
      View in: Publisher Site   Mentions:
    46. Suicide ideation and behaviours after STN and GPi DBS surgery for Parkinson's disease: results from a randomised, controlled trial. J Neurol Neurosurg Psychiatry. 2013 Oct; 84(10):1113-8. Weintraub D, Duda JE, Carlson K, Luo P, Sagher O, Stern M, Follett KA, Reda D, Weaver FM. PMID: 23667214.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    47. Radially branched deployment for more efficient cell transplantation at the scale of the human brain. Stereotact Funct Neurosurg. 2013; 91(2):92-103. Silvestrini MT, Yin D, Coppes VG, Mann P, Martin AJ, Larson PS, Starr PA, Gupta N, Panter SS, Desai TA, Lim DA. PMID: 23343609.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    48. A stroke of silence: tinnitus suppression following placement of a deep brain stimulation electrode with infarction in area LC. J Neurosurg. 2013 Jan; 118(1):192-4. Larson PS, Cheung SW. PMID: 23082889.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    49. Clinical outcomes of PD patients having bilateral STN DBS using high-field interventional MR-imaging for lead placement. Clin Neurol Neurosurg. 2013 Jun; 115(6):708-12. Ostrem JL, Galifianakis NB, Markun LC, Grace JK, Martin AJ, Starr PA, Larson PS. PMID: 22944465.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    50. Securing dual ipsilateral leads through a single burr hole in deep brain stimulation surgery: technical note. Stereotact Funct Neurosurg. 2012; 90(6):361-4. Potts MB, Larson PS. PMID: 22922401.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    51. Randomized trial of deep brain stimulation for Parkinson disease: thirty-six-month outcomes. Neurology. 2012 Jul 03; 79(1):55-65. Weaver FM, Follett KA, Stern M, Luo P, Harris CL, Hur K, Marks WJ, Rothlind J, Sagher O, Moy C, Pahwa R, Burchiel K, Hogarth P, Lai EC, Duda JE, Holloway K, Samii A, Horn S, Bronstein JM, Stoner G, Starr PA, Simpson R, Baltuch G, De Salles A, Huang GD, Reda DJ. PMID: 22722632.
      View in: PubMed   Mentions: 93     Fields:    Translation:Humans
    52. Acute effects of thalamic deep brain stimulation and thalamotomy on sensorimotor cortex local field potentials in essential tremor. Clin Neurophysiol. 2012 Nov; 123(11):2232-8. Air EL, Ryapolova-Webb E, de Hemptinne C, Ostrem JL, Galifianakis NB, Larson PS, Chang EF, Starr PA. PMID: 22633916.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    53. Long-term evaluation of a phase 1 study of AADC gene therapy for Parkinson's disease. Hum Gene Ther. 2012 Apr; 23(4):377-81. Mittermeyer G, Christine CW, Rosenbluth KH, Baker SL, Starr P, Larson P, Kaplan PL, Forsayeth J, Aminoff MJ, Bankiewicz KS. PMID: 22424171.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCellsCTClinical Trials
    54. An optimized system for interventional magnetic resonance imaging-guided stereotactic surgery: preliminary evaluation of targeting accuracy. Neurosurgery. 2012 Mar; 70(1 Suppl Operative):95-103; discussion 103. Larson PS, Starr PA, Bates G, Tansey L, Richardson RM, Martin AJ. PMID: 21796000.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    55. Deep brain stimulation in area LC controllably triggers auditory phantom percepts. Neurosurgery. 2012 Feb; 70(2):398-405; discussion 405-6. Larson PS, Cheung SW. PMID: 21849922.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    56. Abnormal T2-weighted MRI signal surrounding leads in a subset of deep brain stimulation patients. Stereotact Funct Neurosurg. 2011; 89(5):311-7. Englot DJ, Glastonbury CM, Larson PS. PMID: 21894061.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    57. Lead cap localization using ultrasound in deep brain stimulation surgery: technical note. Minim Invasive Neurosurg. 2011 Feb; 54(1):48-9. Englot DJ, Chang EF, Larson PS. PMID: 21506069.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    58. Novel platform for MRI-guided convection-enhanced delivery of therapeutics: preclinical validation in nonhuman primate brain. Stereotact Funct Neurosurg. 2011; 89(3):141-51. Richardson RM, Kells AP, Martin AJ, Larson PS, Starr PA, Piferi PG, Bates G, Tansey L, Rosenbluth KH, Bringas JR, Berger MS, Bankiewicz KS. PMID: 21494065.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    59. Intraoperative computed tomography for deep brain stimulation surgery: technique and accuracy assessment. Neurosurgery. 2011 Mar; 68(1 Suppl Operative):114-24; discussion 124. Shahlaie K, Larson PS, Starr PA. PMID: 21206322.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    60. Interventional MRI-guided putaminal delivery of AAV2-GDNF for a planned clinical trial in Parkinson's disease. Mol Ther. 2011 Jun; 19(6):1048-57. Richardson RM, Kells AP, Rosenbluth KH, Salegio EA, Fiandaca MS, Larson PS, Starr PA, Martin AJ, Lonser RR, Federoff HJ, Forsayeth JR, Bankiewicz KS. PMID: 21343917.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    61. Incidence and management of venous air embolisms during awake deep brain stimulation surgery in a large clinical series. Stereotact Funct Neurosurg. 2011; 89(2):76-82. Chang EF, Cheng JS, Richardson RM, Lee C, Starr PA, Larson PS. PMID: 21293166.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    62. Chapter 18 Safety Concerns and Limitations. Essential Neuromodulation. 2011 Jan 1; 397-412. Paul S. Larson, Alastair J. Martin, Ali Rezai, Jeffrey E. Arle. .
      View in: Publisher Site   Mentions:
    63. Human/nonhuman primate AC-PC ratio--considerations for translational brain measurements. J Neurosci Methods. 2011 Mar 15; 196(1):124-30. Fiandaca MS, Salegio EA, Yin D, Richardson RM, Valles FE, Larson PS, Starr PA, Lonser RR, Bankiewicz KS. PMID: 21185868.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    64. Qualitative imaging of adeno-associated virus serotype 2-human aromatic L-amino acid decarboxylase gene therapy in a phase I study for the treatment of Parkinson disease. Neurosurgery. 2010 Nov; 67(5):1377-85. Valles F, Fiandaca MS, Eberling JL, Starr PA, Larson PS, Christine CW, Forsayeth J, Richardson RM, Su X, Aminoff MJ, Bankiewicz KS. PMID: 20871425.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCellsCTClinical Trials
    65. Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial. Lancet Neurol. 2010 Dec; 9(12):1164-1172. Marks WJ, Bartus RT, Siffert J, Davis CS, Lozano A, Boulis N, Vitek J, Stacy M, Turner D, Verhagen L, Bakay R, Watts R, Guthrie B, Jankovic J, Simpson R, Tagliati M, Alterman R, Stern M, Baltuch G, Starr PA, Larson PS, Ostrem JL, Nutt J, Kieburtz K, Kordower JH, Olanow CW. PMID: 20970382.
      View in: PubMed   Mentions: 191     Fields:    Translation:HumansCellsCTClinical Trials
    66. Minimally invasive surgery for movement disorders. Neurosurg Clin N Am. 2010 Oct; 21(4):691-8, vii. Larson PS. PMID: 20947036.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    67. Tinnitus modulation by deep brain stimulation in locus of caudate neurons (area LC). Neuroscience. 2010 Sep 15; 169(4):1768-78. Cheung SW, Larson PS. PMID: 20541595.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    68. Pallidal versus subthalamic deep-brain stimulation for Parkinson's disease. N Engl J Med. 2010 Jun 03; 362(22):2077-91. Follett KA, Weaver FM, Stern M, Hur K, Harris CL, Luo P, Marks WJ, Rothlind J, Sagher O, Moy C, Pahwa R, Burchiel K, Hogarth P, Lai EC, Duda JE, Holloway K, Samii A, Horn S, Bronstein JM, Stoner G, Starr PA, Simpson R, Baltuch G, De Salles A, Huang GD, Reda DJ. PMID: 20519680.
      View in: PubMed   Mentions: 277     Fields:    Translation:Humans
    69. Subthalamic nucleus deep brain stimulator placement using high-field interventional magnetic resonance imaging and a skull-mounted aiming device: technique and application accuracy. J Neurosurg. 2010 Mar; 112(3):479-90. Starr PA, Martin AJ, Ostrem JL, Talke P, Levesque N, Larson PS. PMID: 19681683.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    70. Physiological identification of the human pedunculopontine nucleus. J Neurol Neurosurg Psychiatry. 2010 Jan; 81(1):80-6. Shimamoto SA, Larson PS, Ostrem JL, Glass GA, Turner RS, Starr PA. PMID: 19828478.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    71. Safety and tolerability of putaminal AADC gene therapy for Parkinson disease. Neurology. 2009 Nov 17; 73(20):1662-9. Christine CW, Starr PA, Larson PS, Eberling JL, Jagust WJ, Hawkins RA, VanBrocklin HF, Wright JF, Bankiewicz KS, Aminoff MJ. PMID: 19828868.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansCTClinical Trials
    72. Software requirements for interventional MR in restorative and functional neurosurgery. Neurosurg Clin N Am. 2009 Apr; 20(2):179-86. Martin AJ, Starr PA, Larson PS. PMID: 19555880.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    73. Intraoperative MRI in functional neurosurgery. Preface. Neurosurg Clin N Am. 2009 Apr; 20(2):xi. Lim DA, Larson PS. PMID: 19555874.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    74. Implantation of deep brain stimulator electrodes using interventional MRI. Neurosurg Clin N Am. 2009 Apr; 20(2):193-203. Starr PA, Martin AJ, Larson PS. PMID: 19555882.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    75. Fluoroscopic, EMG-guided injection of botulinum toxin into the longus colli for the treatment of anterocollis. Parkinsonism Relat Disord. 2009 Sep; 15(8):610-3. Glass GA, Ku S, Ostrem JL, Heath S, Larson PS. PMID: 19250855.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    76. Bilateral deep brain stimulation vs best medical therapy for patients with advanced Parkinson disease: a randomized controlled trial. JAMA. 2009 Jan 07; 301(1):63-73. Weaver FM, Follett K, Stern M, Hur K, Harris C, Marks WJ, Rothlind J, Sagher O, Reda D, Moy CS, Pahwa R, Burchiel K, Hogarth P, Lai EC, Duda JE, Holloway K, Samii A, Horn S, Bronstein J, Stoner G, Heemskerk J, Huang GD. PMID: 19126811.
      View in: PubMed   Mentions: 299     Fields:    Translation:Humans
    77. Interventional magnetic resonance guidance of deep brain stimulator implantation for Parkinson disease. Top Magn Reson Imaging. 2009 Jan; 19(4):213-21. Martin AJ, Larson PS, Ostrem JL, Starr PA. PMID: 19148038.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    78. Gene and cell delivery to the degenerated striatum: status of preclinical efforts in primate models. Neurosurgery. 2008 Oct; 63(4):629-442; dicussion 642-4. Richardson RM, Larson PS, Bankiewicz KS. PMID: 18981876.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    79. Results from a phase I safety trial of hAADC gene therapy for Parkinson disease. Neurology. 2008 May 20; 70(21):1980-3. Eberling JL, Jagust WJ, Christine CW, Starr P, Larson P, Bankiewicz KS, Aminoff MJ. PMID: 18401019.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansCTClinical Trials
    80. Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial. Lancet Neurol. 2008 May; 7(5):400-8. Marks WJ, Ostrem JL, Verhagen L, Starr PA, Larson PS, Bakay RA, Taylor R, Cahn-Weiner DA, Stoessl AJ, Olanow CW, Bartus RT. PMID: 18387850.
      View in: PubMed   Mentions: 161     Fields:    Translation:HumansCellsCTClinical Trials
    81. Minimally invasive precision brain access using prospective stereotaxy and a trajectory guide. J Magn Reson Imaging. 2008 Apr; 27(4):737-43. Martin AJ, Hall WA, Roark C, Starr PA, Larson PS, Truwit CL. PMID: 18383266.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    82. Deep brain stimulator hardware-related infections: incidence and management in a large series. Neurosurgery. 2008 Feb; 62(2):360-6; discussion 366-7. Sillay KA, Larson PS, Starr PA. PMID: 18382313.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    83. Thalamic deep brain stimulation for essential tremor: relation of lead location to outcome. Neurosurgery. 2008 Feb; 62 Suppl 2:884-94. Papavassiliou E, Rau G, Heath S, Abosch A, Barbaro NM, Larson PS, Lamborn K, Starr PA. PMID: 18596419.
      View in: PubMed   Mentions: 11     Fields:    
    84. Deep brain stimulation for psychiatric disorders. Neurotherapeutics. 2008 Jan; 5(1):50-8. Larson PS. PMID: 18164483.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    85. Technical Alternatives in Performing Deep Brain Stimulator Implantation. Deep Brain Stimulation in Neurological and Psychiatric Disorders. 2008 Jan 1; 99-110. Paul S. Larson. .
      View in: Publisher Site   Mentions:
    86. Magnetic resonance imaging of implanted deep brain stimulators: experience in a large series. Stereotact Funct Neurosurg. 2008; 86(2):92-100. Larson PS, Richardson RM, Starr PA, Martin AJ. PMID: 18073522.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    87. Placement of Subthalamic DBS Electrodes in a Radiology Suite Using Interventional MRI. Proceedings of the Medtronic Forum for Neuroscience and Neuro-Technology 2005. 2007 Jan 1; 37-39. P. A. Starr, A. J. Martin, P. Talke, J. Ostrem, W. K. Sootsman, N. Levesque, J. Meyers, P. S. Larson. .
      View in: Publisher Site   Mentions:
    88. Placement of deep brain stimulator electrodes using real-time high-field interventional magnetic resonance imaging. Magn Reson Med. 2005 Nov; 54(5):1107-14. Martin AJ, Larson PS, Ostrem JL, Keith Sootsman W, Talke P, Weber OM, Levesque N, Myers J, Starr PA. PMID: 16206144.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCTClinical Trials
    89. Thalamic deep brain stimulation for essential tremor: relation of lead location to outcome. Neurosurgery. 2004 May; 54(5):1120-29; discussion 1129-30. Papavassiliou E, Rau G, Heath S, Abosch A, Barbaro NM, Larson PS, Lamborn K, Starr PA. PMID: 15113466.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    90. Frameless stereotactic neurosurgery using intraoperative magnetic resonance imaging: stereotactic brain biopsy. Neurosurgery. 2000 Nov; 47(5):1138-45; discussion 1145-6. Moriarty TM, Quinones-Hinojosa A, Larson PS, Alexander E, Gleason PL, Schwartz RB, Jolesz FA, Black PM. PMID: 11063107.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    91. Traumatic intracranial aneurysms. Neurosurg Focus. 2000 Jan 15; 8(1):e4. Larson PS, Reisner A, Morassutti DJ, Abdulhadi B, Harpring JE. PMID: 16906700.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    92. Emergency magnetic resonance imaging of cervical spinal cord injuries: clinical correlation and prognosis. Neurosurgery. 1999 Oct; 45(4):956-7. Larson PS, Christiano JA, Raque GH, Shields CB. PMID: 10515498.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    93. Visuomotor learning in cerebellar patients. Behav Brain Res. 1996 Nov; 81(1-2):99-113. Timmann D, Shimansky Y, Larson PS, Wunderlich DA, Stelmach GE, Bloedel JR. PMID: 8950006.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    94. Real time operations of the cerebellar cortex. Can J Neurol Sci. 1993 May; 20 Suppl 3:S7-18. Bloedel JR, Bracha V, Larson PS. PMID: 8334594.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    Paul's Networks
    Concepts (263)
    Derived automatically from this person's publications.
    _
    Co-Authors (46)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _