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Paul Larson, MD

Title(s)Professor, Neurological Surgery
SchoolSchool of Medicine
Phone415-502-2885
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
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    University of Arizona, Tucson, AZ1995MD
    University of Louisville, Louisville, KY2001Neurosurgery Residency

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    Dr. Paul Larson is Professor and Vice Chair of Neurological Surgery at the University of California San Francisco, Chief of Neurosurgery at the San Francisco VA Medical Center and Surgical Director of the Parkinson’s Disease Research, Education and Clinical Center. He specializes in functional neurosurgery, specifically deep brain stimulation for movement disorders and MR-guided procedures. The Surgical Movement Disorders program at UCSF and the SFVA is one of the largest and most active centers in the world.

    Dr. Larson’s research program is built around three core areas of interest. He has 20 years of experience in interventional MRI-guided surgery, and was one of three researchers at UCSF that started and developed the field of iMRI-guided stereotactic surgery for DBS placement and drug delivery. He has had continuous funding for device development and clinical trials in interventional MRI procedures since 2003. Secondly, his group at UCSF has been at the forefront of gene therapy for Parkinson’s disease. They have had a leadership role in 4 of the 7 human trials completed worldwide to date, and have performed more than 1/3 of all Parkinson’s gene therapy procedures ever performed. He is currently the PI for a fifth gene therapy trial using convection enhanced, iMRI-guided delivery of AAV2-AADC into the putamen of patients with Parkinson’s disease. Finally, Dr. Larson has a significant interest in the neurobiology and underlying brain circuitry of phantom auditory disorders including tinnitus. His work in this area with Dr. Steven Cheung has led to the discovery of a new region of brain involved in auditory perception, as well as a new proposed model of the basal ganglia for chronic tinnitus. They have a U01 grant from the NIDCD to study the use of DBS in the caudate nucleus in patients with severe, medically refractory tinnitus.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Cheung SW, Racine CA, Henderson-Sabes J, Demopoulos C, Molinaro AM, Heath S, Nagarajan SS, Bourne AL, Rietcheck JE, Wang SS, Larson PS. Phase I trial of caudate deep brain stimulation for treatment-resistant tinnitus. J Neurosurg. 2019 Sep 24; 1-10. PMID: 31553940.
      View in: PubMed
    2. Chen W, de Hemptinne C, Leibbrand M, Miller AM, Larson PS, Starr PA. Altered Prefrontal Theta and Gamma Activity during an Emotional Face Processing Task in Parkinson Disease. J Cogn Neurosci. 2019 Nov; 31(11):1768-1776. PMID: 31322465.
      View in: PubMed
    3. Christine CW, Bankiewicz KS, Van Laar AD, Richardson RM, Ravina B, Kells AP, Boot B, Martin AJ, Nutt J, Thompson ME, Larson PS. Magnetic resonance imaging-guided phase 1 trial of putaminal AADC gene therapy for Parkinson's disease. Ann Neurol. 2019 May; 85(5):704-714. PMID: 30802998.
      View in: PubMed
    4. Perez PL, Wang SS, Heath S, Henderson-Sabes J, Mizuiri D, Hinkley LB, Nagarajan SS, Larson PS, Cheung SW. Human caudate nucleus subdivisions in tinnitus modulation. J Neurosurg. 2019 Feb 08; 1-7. PMID: 30738400.
      View in: PubMed
    5. Chan AK, Chan AY, Lau D, Durcanova B, Miller CA, Larson PS, Starr PA, Mummaneni PV. Surgical management of camptocormia in Parkinson's disease: systematic review and meta-analysis. J Neurosurg. 2018 Sep 14; 1-5. PMID: 30215560.
      View in: PubMed
    6. Talbott JF, Cooke DL, Mabray MC, Larson PS, Amans MR, Hetts SW, Wilson MW, Moore T, Salegio EA. Accuracy of image-guided percutaneous injection into a phantom spinal cord utilizing flat panel detector CT with MR fusion and integrated navigational software. J Neurointerv Surg. 2018 Dec; 10(12):e37. PMID: 29666181.
      View in: PubMed
    7. Kundishora AJ, Englot DJ, Starr PA, Martin AJ, Larson PS. Venous Thromboembolism during Interventional MRI-Guided Stereotactic Surgery. Stereotact Funct Neurosurg. 2018; 96(1):40-45. PMID: 29495014.
      View in: PubMed
    8. Southwell DG, Birk HS, Larson PS, Starr PA, Sugrue LP, Auguste KI. Laser ablative therapy of sessile hypothalamic hamartomas in children using interventional MRI: report of 5 cases. J Neurosurg Pediatr. 2018 05; 21(5):460-465. PMID: 29451455.
      View in: PubMed
    9. Larson PS, Starr PA, Martin AJ. Deep Brain Stimulation: Interventional and Intraoperative MRI Approaches. Prog Neurol Surg. 2018; 33:187-197. PMID: 29332083.
      View in: PubMed
    10. Southwell DG, Rutkowski MJ, San Luciano M, Racine C, Ostrem J, Starr PA, Larson PS. Before and after the veterans affairs cooperative program 468 study: Deep brain stimulator target selection for treatment of Parkinson's disease. Parkinsonism Relat Disord. 2018 03; 48:40-44. PMID: 29249683.
      View in: PubMed
    11. Martin AJ, Starr PA, Ostrem JL, Larson PS. Hemorrhage Detection and Incidence during Magnetic Resonance-Guided Deep Brain Stimulator Implantations. Stereotact Funct Neurosurg. 2017; 95(5):307-314. PMID: 28889128.
      View in: PubMed
    12. Srejic U, Larson P, Bickler PE. Little Black Boxes: Noncardiac Implantable Electronic Medical Devices and Their Anesthetic and Surgical Implications. Anesth Analg. 2017 07; 125(1):124-138. PMID: 28489640.
      View in: PubMed
    13. Larson PS, Willie JT, Vadivelu S, Azmi-Ghadimi H, Nichols A, Fauerbach LL, Johnson HB, Graham D. MRI-guided stereotactic neurosurgical procedures in a diagnostic MRI suite: Background and safe practice recommendations. J Healthc Risk Manag. 2017 Jul; 37(1):31-39. PMID: 28719087.
      View in: PubMed
    14. LaHue SC, Ostrem JL, Galifianakis NB, San Luciano M, Ziman N, Wang S, Racine CA, Starr PA, Larson PS, Katz M. Parkinson's disease patient preference and experience with various methods of DBS lead placement. Parkinsonism Relat Disord. 2017 Aug; 41:25-30. PMID: 28615151.
      View in: PubMed
    15. Larson PS, Vadivelu S, Azmi-Ghadimi H, Nichols A, Fauerbach L, Johnson HB. Neurosurgical laser ablation and MR thermometry: Risks of multisite workflow pattern. J Healthc Risk Manag. 2017 Apr; 36(4):7-18. PMID: 28415147.
      View in: PubMed
    16. Wharen RE, Okun MS, Guthrie BL, Uitti RJ, Larson P, Foote K, Walker H, Marshall FJ, Schwalb J, Ford B, Jankovic J, Simpson R, Dashtipour K, Phibbs F, Neimat JS, Stewart RM, Peichel D, Pahwa R, Ostrem JL. Thalamic DBS with a constant-current device in essential tremor: A controlled clinical trial. Parkinsonism Relat Disord. 2017 Jul; 40:18-26. PMID: 28400200.
      View in: PubMed
    17. Rolston JD, Englot DJ, Starr PA, Larson PS. An unexpectedly high rate of revisions and removals in deep brain stimulation surgery: Analysis of multiple databases. Parkinsonism Relat Disord. 2016 12; 33:72-77. PMID: 27645504.
      View in: PubMed
    18. Ramos AD, Rolston JD, Gauger GE, Larson PS. Spinal Subdural Abscess Following Laminectomy for Symptomatic Stenosis: A Report of 2 Cases and Review of the Literature. Am J Case Rep. 2016 Jul 12; 17:476-83. PMID: 27402228.
      View in: PubMed
    19. Han SJ, Bankiewicz K, Butowski NA, Larson PS, Aghi MK. Interventional MRI-guided catheter placement and real time drug delivery to the central nervous system. Expert Rev Neurother. 2016 06; 16(6):635-9. PMID: 27054877.
      View in: PubMed
    20. Southwell DG, Narvid JA, Martin AJ, Qasim SE, Starr PA, Larson PS. Comparison of Deep Brain Stimulation Lead Targeting Accuracy and Procedure Duration between 1.5- and 3-Tesla Interventional Magnetic Resonance Imaging Systems: An Initial 12-Month Experience. Stereotact Funct Neurosurg. 2016; 94(2):102-7. PMID: 27093443.
      View in: PubMed
    21. Martin AJ, Larson PS, Ziman N, Levesque N, Volz M, Ostrem JL, Starr PA. Deep brain stimulator implantation in a diagnostic MRI suite: infection history over a 10-year period. J Neurosurg. 2017 Jan; 126(1):108-113. PMID: 27015399.
      View in: PubMed
    22. Marks WJ, Baumann TL, Bartus RT. Long-Term Safety of Patients with Parkinson's Disease Receiving rAAV2-Neurturin (CERE-120) Gene Transfer. Hum Gene Ther. 2016 07; 27(7):522-7. PMID: 26711317.
      View in: PubMed
    23. Rowland NC, Kalia SK, Kalia LV, Larson PS, Lim DA, Bankiewicz KS. Merging DBS with viral vector or stem cell implantation: "hybrid" stereotactic surgery as an evolution in the surgical treatment of Parkinson's disease. Mol Ther Methods Clin Dev. 2016; 3:15051. PMID: 26817024.
      View in: PubMed
    24. Ostrem JL, Ziman N, Galifianakis NB, Starr PA, Luciano MS, Katz M, Racine CA, Martin AJ, Markun LC, Larson PS. Clinical outcomes using ClearPoint interventional MRI for deep brain stimulation lead placement in Parkinson's disease. J Neurosurg. 2016 Apr; 124(4):908-16. PMID: 26495947.
      View in: PubMed
    25. Warren Olanow C, Bartus RT, Baumann TL, Factor S, Boulis N, Stacy M, Turner DA, Marks W, Larson P, Starr PA, Jankovic J, Simpson R, Watts R, Guthrie B, Poston K, Henderson JM, Stern M, Baltuch G, Goetz CG, Herzog C, Kordower JH, Alterman R, Lozano AM, Lang AE. Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: A double-blind, randomized, controlled trial. Ann Neurol. 2015 Aug; 78(2):248-57. PMID: 26061140.
      View in: PubMed
    26. Mabray MC, Datta S, Lillaney PV, Moore T, Gehrisch S, Talbott JF, Levitt MR, Ghodke BV, Larson PS, Cooke DL. Accuracy of flat panel detector CT with integrated navigational software with and without MR fusion for single-pass needle placement. J Neurointerv Surg. 2016 Jul; 8(7):731-5. PMID: 26047903.
      View in: PubMed
    27. Katz M, Luciano MS, Carlson K, Luo P, Marks WJ, Larson PS, Starr PA, Follett KA, Weaver FM, Stern MB, Reda DJ, Ostrem JL. Differential effects of deep brain stimulation target on motor subtypes in Parkinson's disease. Ann Neurol. 2015 Apr; 77(4):710-9. PMID: 25627340.
      View in: PubMed
    28. Chabardes S, Isnard S, Castrioto A, Oddoux M, Fraix V, Carlucci L, Payen JF, Krainik A, Krack P, Larson P, Le Bas JF. Surgical implantation of STN-DBS leads using intraoperative MRI guidance: technique, accuracy, and clinical benefit at 1-year follow-up. Acta Neurochir (Wien). 2015 Apr; 157(4):729-37. PMID: 25788414.
      View in: PubMed
    29. Rowland NC, Starr PA, Larson PS, Ostrem JL, Marks WJ, Lim DA. Combining cell transplants or gene therapy with deep brain stimulation for Parkinson's disease. Mov Disord. 2015 Feb; 30(2):190-5. PMID: 25521796.
      View in: PubMed
    30. Yoon JH, Larson P, Grandelis A, La C, Cui E, Carter CS, Minzenberg MJ. Delay Period Activity of the Substantia Nigra during Proactive Control of Response Selection as Determined by a Novel fMRI Localization Method. J Cogn Neurosci. 2015 Jun; 27(6):1238-48. PMID: 25514657.
      View in: PubMed
    31. Rothlind JC, York MK, Carlson K, Luo P, Marks WJ, Weaver FM, Stern M, Follett K, Reda D. Neuropsychological changes following deep brain stimulation surgery for Parkinson's disease: comparisons of treatment at pallidal and subthalamic targets versus best medical therapy. J Neurol Neurosurg Psychiatry. 2015 Jun; 86(6):622-9. PMID: 25185211.
      View in: PubMed
    32. Silvestrini MT, Yin D, Martin AJ, Coppes VG, Mann P, Larson PS, Starr PA, Zeng X, Gupta N, Panter SS, Desai TA, Lim DA. Interventional magnetic resonance imaging-guided cell transplantation into the brain with radially branched deployment. Mol Ther. 2015 Jan; 23(1):119-29. PMID: 25138755.
      View in: PubMed
    33. Starr PA, Markun LC, Larson PS, Volz MM, Martin AJ, Ostrem JL. Interventional MRI-guided deep brain stimulation in pediatric dystonia: first experience with the ClearPoint system. J Neurosurg Pediatr. 2014 Oct; 14(4):400-8. PMID: 25084088.
      View in: PubMed
    34. Larson PS. Deep brain stimulation for movement disorders. Neurotherapeutics. 2014 Jul; 11(3):465-74. PMID: 24833244.
      View in: PubMed
    35. Ivan ME, Yarlagadda J, Saxena AP, Martin AJ, Starr PA, Sootsman WK, Larson PS. Brain shift during bur hole-based procedures using interventional MRI. J Neurosurg. 2014 Jul; 121(1):149-60. PMID: 24785326.
      View in: PubMed
    36. Vega RA, Holloway KL, Larson PS. Image-guided deep brain stimulation. Neurosurg Clin N Am. 2014 Jan; 25(1):159-72. PMID: 24262907.
      View in: PubMed
    37. Weintraub D, Duda JE, Carlson K, Luo P, Sagher O, Stern M, Follett KA, Reda D, Weaver FM. Suicide ideation and behaviours after STN and GPi DBS surgery for Parkinson's disease: results from a randomised, controlled trial. J Neurol Neurosurg Psychiatry. 2013 Oct; 84(10):1113-8. PMID: 23667214.
      View in: PubMed
    38. Silvestrini MT, Yin D, Coppes VG, Mann P, Martin AJ, Larson PS, Starr PA, Gupta N, Panter SS, Desai TA, Lim DA. Radially branched deployment for more efficient cell transplantation at the scale of the human brain. Stereotact Funct Neurosurg. 2013; 91(2):92-103. PMID: 23343609.
      View in: PubMed
    39. Larson PS, Cheung SW. A stroke of silence: tinnitus suppression following placement of a deep brain stimulation electrode with infarction in area LC. J Neurosurg. 2013 Jan; 118(1):192-4. PMID: 23082889.
      View in: PubMed
    40. Ostrem JL, Galifianakis NB, Markun LC, Grace JK, Martin AJ, Starr PA, Larson PS. Clinical outcomes of PD patients having bilateral STN DBS using high-field interventional MR-imaging for lead placement. Clin Neurol Neurosurg. 2013 Jun; 115(6):708-12. PMID: 22944465.
      View in: PubMed
    41. Potts MB, Larson PS. Securing dual ipsilateral leads through a single burr hole in deep brain stimulation surgery: technical note. Stereotact Funct Neurosurg. 2012; 90(6):361-4. PMID: 22922401.
      View in: PubMed
    42. Weaver FM, Follett KA, Stern M, Luo P, Harris CL, Hur K, Marks WJ, Rothlind J, Sagher O, Moy C, Pahwa R, Burchiel K, Hogarth P, Lai EC, Duda JE, Holloway K, Samii A, Horn S, Bronstein JM, Stoner G, Starr PA, Simpson R, Baltuch G, De Salles A, Huang GD, Reda DJ. Randomized trial of deep brain stimulation for Parkinson disease: thirty-six-month outcomes. Neurology. 2012 Jul 03; 79(1):55-65. PMID: 22722632.
      View in: PubMed
    43. Air EL, Ryapolova-Webb E, de Hemptinne C, Ostrem JL, Galifianakis NB, Larson PS, Chang EF, Starr PA. Acute effects of thalamic deep brain stimulation and thalamotomy on sensorimotor cortex local field potentials in essential tremor. Clin Neurophysiol. 2012 Nov; 123(11):2232-8. PMID: 22633916.
      View in: PubMed
    44. Mittermeyer G, Christine CW, Rosenbluth KH, Baker SL, Starr P, Larson P, Kaplan PL, Forsayeth J, Aminoff MJ, Bankiewicz KS. Long-term evaluation of a phase 1 study of AADC gene therapy for Parkinson's disease. Hum Gene Ther. 2012 Apr; 23(4):377-81. PMID: 22424171.
      View in: PubMed
    45. Larson PS, Starr PA, Bates G, Tansey L, Richardson RM, Martin AJ. An optimized system for interventional magnetic resonance imaging-guided stereotactic surgery: preliminary evaluation of targeting accuracy. Neurosurgery. 2012 Mar; 70(1 Suppl Operative):95-103; discussion 103. PMID: 21796000.
      View in: PubMed
    46. Larson PS, Cheung SW. Deep brain stimulation in area LC controllably triggers auditory phantom percepts. Neurosurgery. 2012 Feb; 70(2):398-405; discussion 405-6. PMID: 21849922.
      View in: PubMed
    47. Englot DJ, Glastonbury CM, Larson PS. Abnormal T2-weighted MRI signal surrounding leads in a subset of deep brain stimulation patients. Stereotact Funct Neurosurg. 2011; 89(5):311-7. PMID: 21894061.
      View in: PubMed
    48. Englot DJ, Chang EF, Larson PS. Lead cap localization using ultrasound in deep brain stimulation surgery: technical note. Minim Invasive Neurosurg. 2011 Feb; 54(1):48-9. PMID: 21506069.
      View in: PubMed
    49. Richardson RM, Kells AP, Martin AJ, Larson PS, Starr PA, Piferi PG, Bates G, Tansey L, Rosenbluth KH, Bringas JR, Berger MS, Bankiewicz KS. Novel platform for MRI-guided convection-enhanced delivery of therapeutics: preclinical validation in nonhuman primate brain. Stereotact Funct Neurosurg. 2011; 89(3):141-51. PMID: 21494065.
      View in: PubMed
    50. Shahlaie K, Larson PS, Starr PA. Intraoperative computed tomography for deep brain stimulation surgery: technique and accuracy assessment. Neurosurgery. 2011 Mar; 68(1 Suppl Operative):114-24; discussion 124. PMID: 21206322.
      View in: PubMed
    51. Richardson RM, Kells AP, Rosenbluth KH, Salegio EA, Fiandaca MS, Larson PS, Starr PA, Martin AJ, Lonser RR, Federoff HJ, Forsayeth JR, Bankiewicz KS. Interventional MRI-guided putaminal delivery of AAV2-GDNF for a planned clinical trial in Parkinson's disease. Mol Ther. 2011 Jun; 19(6):1048-57. PMID: 21343917.
      View in: PubMed
    52. Chang EF, Cheng JS, Richardson RM, Lee C, Starr PA, Larson PS. Incidence and management of venous air embolisms during awake deep brain stimulation surgery in a large clinical series. Stereotact Funct Neurosurg. 2011; 89(2):76-82. PMID: 21293166.
      View in: PubMed
    53. Fiandaca MS, Salegio EA, Yin D, Richardson RM, Valles FE, Larson PS, Starr PA, Lonser RR, Bankiewicz KS. Human/nonhuman primate AC-PC ratio--considerations for translational brain measurements. J Neurosci Methods. 2011 Mar 15; 196(1):124-30. PMID: 21185868.
      View in: PubMed
    54. Valles F, Fiandaca MS, Eberling JL, Starr PA, Larson PS, Christine CW, Forsayeth J, Richardson RM, Su X, Aminoff MJ, Bankiewicz KS. Qualitative imaging of adeno-associated virus serotype 2-human aromatic L-amino acid decarboxylase gene therapy in a phase I study for the treatment of Parkinson disease. Neurosurgery. 2010 Nov; 67(5):1377-85. PMID: 20871425.
      View in: PubMed
    55. Marks WJ, Bartus RT, Siffert J, Davis CS, Lozano A, Boulis N, Vitek J, Stacy M, Turner D, Verhagen L, Bakay R, Watts R, Guthrie B, Jankovic J, Simpson R, Tagliati M, Alterman R, Stern M, Baltuch G, Starr PA, Larson PS, Ostrem JL, Nutt J, Kieburtz K, Kordower JH, Olanow CW. Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial. Lancet Neurol. 2010 Dec; 9(12):1164-1172. PMID: 20970382.
      View in: PubMed
    56. Larson PS. Minimally invasive surgery for movement disorders. Neurosurg Clin N Am. 2010 Oct; 21(4):691-8, vii. PMID: 20947036.
      View in: PubMed
    57. Cheung SW, Larson PS. Tinnitus modulation by deep brain stimulation in locus of caudate neurons (area LC). Neuroscience. 2010 Sep 15; 169(4):1768-78. PMID: 20541595.
      View in: PubMed
    58. Follett KA, Weaver FM, Stern M, Hur K, Harris CL, Luo P, Marks WJ, Rothlind J, Sagher O, Moy C, Pahwa R, Burchiel K, Hogarth P, Lai EC, Duda JE, Holloway K, Samii A, Horn S, Bronstein JM, Stoner G, Starr PA, Simpson R, Baltuch G, De Salles A, Huang GD, Reda DJ. Pallidal versus subthalamic deep-brain stimulation for Parkinson's disease. N Engl J Med. 2010 Jun 03; 362(22):2077-91. PMID: 20519680.
      View in: PubMed
    59. Starr PA, Martin AJ, Ostrem JL, Talke P, Levesque N, Larson PS. Subthalamic nucleus deep brain stimulator placement using high-field interventional magnetic resonance imaging and a skull-mounted aiming device: technique and application accuracy. J Neurosurg. 2010 Mar; 112(3):479-90. PMID: 19681683.
      View in: PubMed
    60. Christine CW, Starr PA, Larson PS, Eberling JL, Jagust WJ, Hawkins RA, VanBrocklin HF, Wright JF, Bankiewicz KS, Aminoff MJ. Safety and tolerability of putaminal AADC gene therapy for Parkinson disease. Neurology. 2009 Nov 17; 73(20):1662-9. PMID: 19828868.
      View in: PubMed
    61. Shimamoto SA, Larson PS, Ostrem JL, Glass GA, Turner RS, Starr PA. Physiological identification of the human pedunculopontine nucleus. J Neurol Neurosurg Psychiatry. 2010 Jan; 81(1):80-6. PMID: 19828478.
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    62. Martin AJ, Starr PA, Larson PS. Software requirements for interventional MR in restorative and functional neurosurgery. Neurosurg Clin N Am. 2009 Apr; 20(2):179-86. PMID: 19555880.
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    63. Lim DA, Larson PS. Intraoperative MRI in functional neurosurgery. Preface. Neurosurg Clin N Am. 2009 Apr; 20(2):xi. PMID: 19555874.
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    64. Starr PA, Martin AJ, Larson PS. Implantation of deep brain stimulator electrodes using interventional MRI. Neurosurg Clin N Am. 2009 Apr; 20(2):193-203. PMID: 19555882.
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    65. Glass GA, Ku S, Ostrem JL, Heath S, Larson PS. Fluoroscopic, EMG-guided injection of botulinum toxin into the longus colli for the treatment of anterocollis. Parkinsonism Relat Disord. 2009 Sep; 15(8):610-3. PMID: 19250855.
      View in: PubMed
    66. Weaver FM, Follett K, Stern M, Hur K, Harris C, Marks WJ, Rothlind J, Sagher O, Reda D, Moy CS, Pahwa R, Burchiel K, Hogarth P, Lai EC, Duda JE, Holloway K, Samii A, Horn S, Bronstein J, Stoner G, Heemskerk J, Huang GD. Bilateral deep brain stimulation vs best medical therapy for patients with advanced Parkinson disease: a randomized controlled trial. JAMA. 2009 Jan 07; 301(1):63-73. PMID: 19126811.
      View in: PubMed
    67. Martin AJ, Larson PS, Ostrem JL, Starr PA. Interventional magnetic resonance guidance of deep brain stimulator implantation for Parkinson disease. Top Magn Reson Imaging. 2009 Jan; 19(4):213-21. PMID: 19148038.
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    68. Richardson RM, Larson PS, Bankiewicz KS. Gene and cell delivery to the degenerated striatum: status of preclinical efforts in primate models. Neurosurgery. 2008 Oct; 63(4):629-442; dicussion 642-4. PMID: 18981876.
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    69. Eberling JL, Jagust WJ, Christine CW, Starr P, Larson P, Bankiewicz KS, Aminoff MJ. Results from a phase I safety trial of hAADC gene therapy for Parkinson disease. Neurology. 2008 May 20; 70(21):1980-3. PMID: 18401019.
      View in: PubMed
    70. Marks WJ, Ostrem JL, Verhagen L, Starr PA, Larson PS, Bakay RA, Taylor R, Cahn-Weiner DA, Stoessl AJ, Olanow CW, Bartus RT. Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial. Lancet Neurol. 2008 May; 7(5):400-8. PMID: 18387850.
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    71. Martin AJ, Hall WA, Roark C, Starr PA, Larson PS, Truwit CL. Minimally invasive precision brain access using prospective stereotaxy and a trajectory guide. J Magn Reson Imaging. 2008 Apr; 27(4):737-43. PMID: 18383266.
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    72. Papavassiliou E, Rau G, Heath S, Abosch A, Barbaro NM, Larson PS, Lamborn K, Starr PA. Thalamic deep brain stimulation for essential tremor: relation of lead location to outcome. Neurosurgery. 2008 Feb; 62 Suppl 2:884-94. PMID: 18596419.
      View in: PubMed
    73. Sillay KA, Larson PS, Starr PA. Deep brain stimulator hardware-related infections: incidence and management in a large series. Neurosurgery. 2008 Feb; 62(2):360-6; discussion 366-7. PMID: 18382313.
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    74. Larson PS. Deep brain stimulation for psychiatric disorders. Neurotherapeutics. 2008 Jan; 5(1):50-8. PMID: 18164483.
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    75. Larson PS, Richardson RM, Starr PA, Martin AJ. Magnetic resonance imaging of implanted deep brain stimulators: experience in a large series. Stereotact Funct Neurosurg. 2008; 86(2):92-100. PMID: 18073522.
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    76. Martin AJ, Larson PS, Ostrem JL, Keith Sootsman W, Talke P, Weber OM, Levesque N, Myers J, Starr PA. Placement of deep brain stimulator electrodes using real-time high-field interventional magnetic resonance imaging. Magn Reson Med. 2005 Nov; 54(5):1107-14. PMID: 16206144.
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    77. Papavassiliou E, Rau G, Heath S, Abosch A, Barbaro NM, Larson PS, Lamborn K, Starr PA. Thalamic deep brain stimulation for essential tremor: relation of lead location to outcome. Neurosurgery. 2004 May; 54(5):1120-29; discussion 1129-30. PMID: 15113466.
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    78. Moriarty TM, Quinones-Hinojosa A, Larson PS, Alexander E, Gleason PL, Schwartz RB, Jolesz FA, Black PM. Frameless stereotactic neurosurgery using intraoperative magnetic resonance imaging: stereotactic brain biopsy. Neurosurgery. 2000 Nov; 47(5):1138-45; discussion 1145-6. PMID: 11063107.
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    79. Larson PS, Reisner A, Morassutti DJ, Abdulhadi B, Harpring JE. Traumatic intracranial aneurysms. Neurosurg Focus. 2000 Jan 15; 8(1):e4. PMID: 16906700.
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    80. Larson PS, Christiano JA, Raque GH, Shields CB. Emergency magnetic resonance imaging of cervical spinal cord injuries: clinical correlation and prognosis. Neurosurgery. 1999 Oct; 45(4):956-7. PMID: 10515498.
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    81. Timmann D, Shimansky Y, Larson PS, Wunderlich DA, Stelmach GE, Bloedel JR. Visuomotor learning in cerebellar patients. Behav Brain Res. 1996 Nov; 81(1-2):99-113. PMID: 8950006.
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    82. Bloedel JR, Bracha V, Larson PS. Real time operations of the cerebellar cortex. Can J Neurol Sci. 1993 May; 20 Suppl 3:S7-18. PMID: 8334594.
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