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Paul Ogongo, PhD

Photo of Paul Ogongo, PhD
Title(s)Assistant Researcher, Medicine
SchoolSchool of Medicine
Address1001 Potrero Avenue, #2837
San Francisco CA 94110
Phone628-206-8101
PronounsHe/Him/His
ORCID ORCID Icon0000-0002-0093-5768 Additional info
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    Collapse Biography 
    Collapse education and training
    University of Nairobi, KenyaBSc 09/2007Zoology
    Jomo Kenyatta University of Agriculture and Technology, KenyaMSc11/2014Molecular Medicine
    University of KwaZulu Natal, South AfricaPhD07/2019Medical Microbiology
    University of California San Francisco, USAPostdoc06/2024Human Immunology
    Collapse awards and honors
    University of California San Francisco2024CFAR Excellence Award for Basic/Translational Research
    University of California San Francisco2024  - 2026ARI/CFAR Merit-Based Scholar Award
    TuBerculosis Vaccine Initiative2023  - 2024TBVI Young Scientist
    University of California San Francisco2023  - 2025TB RAMP Scholar
    Helen Hay Whitney Foundation2021  - 2024Postdoctoral Fellow
    Bill and Melinda Gates Foundation2019  - 2019Rising Star

    Collapse Overview 

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Assessing the Impact of SARS-CoV-2 Spike Mutations on Antibody Binding: A Comparative Assessment of the Wuhan and JN.1 Variants’ Full-Length Spikes in a Multiplex Luminex Assay. Viruses. 2025 Sep 16; 17(9):1248. Waweru WG, Nyakundi NR, Kutima KB, Owuor OS, Konyino KG, Gitonga GJ, Lugano LD, Maina MA, Musyoki MJ, Ochola OL, Omondi OM, Kariuki KC, Ogongo OP, Mwachari MC, Shee SF, Agoti AC, Sande SC, Uyoga US, Kagucia KE, Agweyu AA, Bejon BP, Scott SJ, Warimwe WG, Ochola-Oyier OL, Nyagwange NJ. .
      View in: Publisher Site   Mentions:
    2. Increased circulating Th17 cells and altered CD4 T cell maturation and differentiation in active tuberculosis with type 2 diabetes: a pilot study. Frontiers in Immunology. 2025 Sep 9; 16:1637868. Ogongo OP, Martinez-Lopez MY, Tran TA, Arlehamn AC, Sette SA, Dominguez-Trejo DI, Garza GL, Cruz-Gonzalez CA, Loera-Salazar LR, Rodríguez-Herrera RJ, Aguillón-Durán AG, Garcia-Oropesa GE, Ernst EJ, Restrepo RB. .
      View in: Publisher Site   Mentions:
    3. Driving innovation from discovery to access: Meeting report of the 7 th Global Forum on TB Vaccines (8-10 October 2024, Rio de Janeiro, Brazil). Gates Open Res. 2025; 9:65. Palmer S, Clark RA, Connell BJ, Muwanga VM, Coelho A, Ogongo P, Young C. PMID: 40896556; PMCID: PMC12391588.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. A Novel Approach to Determine the Protective Value of ESAT-6-specific T Cells in Tuberculosis. American Journal of Respiratory and Critical Care Medicine. 2025 May 1; 211(Abstracts):a6576-a6576. Mohapatra MA, Howard HZ, Ogongo OP, Zheng ZW, Ernst EJ. .
      View in: Publisher Site   Mentions:
    5. A Novel Approach to Determine the Protective Value of ESAT-6-specific T Cells in Tuberculosis. American Journal of Respiratory and Critical Care Medicine. 2025 May 1; 211(Abstracts):a6576-a6576. Mohapatra MA, Howard HZ, Ogongo OP, Zheng ZW, Ernst EJ. .
      View in: Publisher Site   Mentions:
    6. Application of microphysiological systems to unravel the mechanisms of schistosomiasis egg extravasation. Front Cell Infect Microbiol. 2025; 15:1521265. Alfred MO, Ochola L, Okeyo K, Bae E, Ogongo P, Odongo D, Njaanake K, Robinson JP. PMID: 40041145; PMCID: PMC11876127.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. A broader evaluation of vaccine-induced T cell immunity against tuberculosis. Frontiers in Tuberculosis. 2024 Jul 19; 2:1435344. Ogongo OP. .
      View in: Publisher Site   Mentions:
    8. B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles. Commun Biol. 2024 05 16; 7(1):584. Krause R, Ogongo P, Tezera L, Ahmed M, Mbano I, Chambers M, Ngoepe A, Magnoumba M, Muema D, Karim F, Khan K, Lumamba K, Nargan K, Madansein R, Steyn A, Shalek AK, Elkington P, Leslie A. PMID: 38755239; PMCID: PMC11099031.
      View in: PubMed   Mentions: 10  Translation:HumansCells
    9. High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL-17 against M. tuberculosis antigen. Front Immunol. 2024; 15:1378040. Ogongo P, Tran A, Marzan F, Gingrich D, Krone M, Aweeka F, Lindestam Arlehamn CS, Martin JN, Deeks SG, Hunt PW, Ernst JD. PMID: 38698866; PMCID: PMC11064812.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    10. Rare Variable M. tuberculosis Antigens induce predominant Th17 responses in human infection. bioRxiv. 2024 Mar 06. Ogongo P, Wassie L, Tran A, Columbus D, Sharling L, Ouma G, Ouma SG, Bobosha K, Lindestam Arlehamn CS, Gandhi NR, Auld SC, Rengarajan J, Day CL, Altman JD, Blumberg HM, Ernst JD, TBRU ASTRa Study Group. PMID: 38496518; PMCID: PMC10942433.
      View in: PubMed   Mentions: 1  
    11. Recognition and control of Mycobacterium tuberculosis-infected cells: from basics to the clinic: a NIAID/WGNV workshop report 2023. 2023. Carly C Young, Mbali N. Mkhonza, Paul Ogongo. .
    12. Finding antigens for TB vaccines: the good, the bad and the useless. Nat Med. 2023 01; 29(1):35-36. Ogongo P, Ernst JD. PMID: 36604539; PMCID: PMC9877171.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    13. Do vaginal microbicides reduce the risk of HIV acquisition in women? Pan Afr Med J. 2022; 43:96. Obiero JA, Ogongo P, Mwethera PG, Wiysonge CS. PMID: 36660088; PMCID: PMC9816879.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. The Road to Elimination: Current State of Schistosomiasis Research and Progress Towards the End Game. Front Immunol. 2022; 13:846108. Ogongo P, Nyakundi RK, Chege GK, Ochola L. PMID: 35592327; PMCID: PMC9112563.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    15. Acquired Clinical Immunity to Malaria in Nonhuman Primates Coinfected with Schistosoma and Plasmodium Parasites. Infect Immun. 2022 02 17; 90(2):e0046421. Nyakundi RK, Hau J, Ogongo P, Nyamongo O, Jeneby M, Akinyi M, Mulei I, Nyundo F, Farah I, Malhotra I, Ozwara H, King CL, Kariuki T. PMID: 34871040; PMCID: PMC8853685.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    16. Repeated Plasmodium falciparum infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire. Sci Transl Med. 2021 12; 13(622):eabe7430. von Borstel A, Chevour P, Arsovski D, Krol JMM, Howson LJ, Berry AA, Day CL, Ogongo P, Ernst JD, Nomicos EYH, Boddey JA, Giles EM, Rossjohn J, Traore B, Lyke KE, Williamson KC, Crompton PD, Davey MS. PMID: 34851691; PMCID: PMC9291638.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    17. A Framework to Identify Antigen-Expanded T Cell Receptor Clusters Within Complex Repertoires. Front Immunol. 2021; 12:735584. Ceglia V, Kelley EJ, Boyle AS, Zurawski S, Mead HL, Harms CE, Blanck JP, Flamar AL, Kirschman JH, Ogongo P, Ernst JD, Levy Y, Zurawski G, Altin JA. PMID: 34917073; PMCID: PMC8670329.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    18. Performance Evaluation of Lateral Flow Assays for Coronavirus Disease-19 Serology. Clin Lab Med. 2022 03; 42(1):31-56. Ochola L, Ogongo P, Mungai S, Gitaka J, Suliman S. PMID: 35153047; PMCID: PMC8563367.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCellsPHPublic Health
    19. Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung. J Clin Invest. 2021 05 17; 131(10). Ogongo P, Tezera LB, Ardain A, Nhamoyebonde S, Ramsuran D, Singh A, Ng'oepe A, Karim F, Naidoo T, Khan K, Dullabh KJ, Fehlings M, Lee BH, Nardin A, Lindestam Arlehamn CS, Sette A, Behar SM, Steyn AJ, Madansein R, Kløverpris HN, Elkington PT, Leslie A. PMID: 33848273; PMCID: PMC8121523.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCellsCTClinical Trials
    20. Topical microbicides for preventing sexually transmitted infections. Cochrane Database Syst Rev. 2021 03 13; 3:CD007961. Obiero J, Ogongo P, Mwethera PG, Wiysonge CS. PMID: 33719075; PMCID: PMC8092571.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    21. Unbiased Profiling Reveals Compartmentalization of Unconventional T-Cells Within the Intestinal Mucosa Irrespective of HIV Infection. Front Immunol. 2020; 11:579743. Magnoumba M, Singh A, Ogongo P, Roider J, Asowata O, Fehlings M, Karim F, Ndung'u T, Anderson F, Leslie A, Kløverpris H. PMID: 33117384; PMCID: PMC7561384.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    22. Single cell transcriptomics of the T cell response to Mycobacterium Tuberculosis reveals phenotypic diversity within and between infected individuals. 2020; (204):(1_Supplement): 225.21.. Junghwa Choi Kirschman; Paul Ogongo; Joel Ernst; John Altin. . View Publication.
    23. Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α. Elife. 2020 02 24; 9. Tezera LB, Bielecka MK, Ogongo P, Walker NF, Ellis M, Garay-Baquero DJ, Thomas K, Reichmann MT, Johnston DA, Wilkinson KA, Ahmed M, Jogai S, Jayasinghe SN, Wilkinson RJ, Mansour S, Thomas GJ, Ottensmeier CH, Leslie A, Elkington PT. PMID: 32091388; PMCID: PMC7058383.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    24. Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs. J Clin Invest. 2020 01 02; 130(1):214-230. Ogongo P, Steyn AJ, Karim F, Dullabh KJ, Awala I, Madansein R, Leslie A, Behar SM. PMID: 31763997; PMCID: PMC6934215.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    25. Publisher Correction: Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis. Nature. 2019 Aug; 572(7768):E10. Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, Ulland TK, Darby M, Park E, Karim F, Melocchi L, Madansein R, Dullabh KJ, Dunlap M, Marin-Agudelo N, Ebihara T, Ndung'u T, Kaushal D, Pym AS, Kolls JK, Steyn A, Zúñiga J, Horsnell W, Yokoyama WM, Shalek AK, Kløverpris HN, Colonna M, Leslie A, Khader SA. PMID: 31337923.
      View in: PubMed   Mentions:    Fields:    
    26. Plasma IL-5 but Not CXCL13 Correlates With Neutralization Breadth in HIV-Infected Children. Front Immunol. 2019; 10:1497. Roider J, Porterfield JZ, Ogongo P, Muenchhoff M, Adland E, Groll A, Morris L, Moore PL, Ndung'u T, Kløverpris H, Goulder PJR, Leslie A. PMID: 31333650; PMCID: PMC6615198.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    27. Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis. Nature. 2019 06; 570(7762):528-532. Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, K Ulland T, Darby M, Park E, Karim F, Melocchi L, Madansein R, Dullabh KJ, Dunlap M, Marin-Agudelo N, Ebihara T, Ndung'u T, Kaushal D, Pym AS, Kolls JK, Steyn A, Zúñiga J, Horsnell W, Yokoyama WM, Shalek AK, Kløverpris HN, Colonna M, Leslie A, Khader SA. PMID: 31168092; PMCID: PMC6626542.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansAnimalsCells
    28. Lung Tissue Resident Memory T-Cells in the Immune Response to Mycobacterium tuberculosis. Front Immunol. 2019; 10:992. Ogongo P, Porterfield JZ, Leslie A. PMID: 31130965; PMCID: PMC6510113.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    29. Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells. Front Immunol. 2018; 9:2539. Attaf M, Malik A, Severinsen MC, Roider J, Ogongo P, Buus S, Ndung'u T, Leslie A, Kløverpris HN, Matthews PC, Sewell AK, Goulder P. PMID: 30487790; PMCID: PMC6246681.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    30. Nifuratel‐Nystatin combination for the treatment of mixed infections of bacterial vaginosis, vulvovaginal candidiasis, and trichomonal vaginitis. Cochrane Database Systematic Reviews. 2018; (4). Jael Obrero, Stephen Rulisa, Paul Ogongo and Charles S Wiysonge. . View Publication.
    31. Diagnosis of schistosomiasis mansoni: an evaluation of existing methods and research towards single worm pair detection. Parasitology. 2018 09; 145(11):1355-1366. Ogongo P, Kariuki TM, Wilson RA. PMID: 29506583.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    32. Protective Potential of Antioxidant Enzymes as Vaccines for Schistosomiasis in a Non-Human Primate Model. Front Immunol. 2015; 6:273. Carvalho-Queiroz C, Nyakundi R, Ogongo P, Rikoi H, Egilmez NK, Farah IO, Kariuki TM, LoVerde PT. PMID: 26082781; PMCID: PMC4451692.
      View in: PubMed   Mentions: 13     Fields:    
    33. International Journal of Infectious Diseases. Identification and evaluation of Schistosoma mansoni proteins as diagnostic targets for schistosomiasis. 2014; 21(365):SUPPLEMENT 1. Paul Ogongo. . View Publication.
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