Peter Sayre, MD, PhD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address400 Parnassus Avenue, #A401
San Francisco CA 94117
Phone415-353-4423
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPost-Doc Fellow/Scholar1996 Medicine
    University of California, San FranciscoResidency

    Collapse Overview 
    Collapse Overview
    Dr. Peter Sayre specializes in adult bone marrow transplantation and other treatments for leukemia, multiple myeloma, lymphoma and Hodgkin's disease.

    Sayre is a director of clinical research at UCSF. His research interests focus on allogeneic stem cell transplants (which use cells from a matching donor) and leukemia in older adults. His work on these subjects has been widely published in medical and other scientific journals.

    Sayre earned an undergraduate degree in philosophy from Yale College, graduating magna cum laude. He earned his medical degree at the Rutgers Robert Wood Johnson Medical School, and he earned a doctorate in immunology at Harvard University. He completed a fellowship in hematology and oncology at UCSF before joining the faculty in 1996.

    Collapse Research 
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    STRUCTURE BASED DESIGN OF TARGETED VIRAL ENV PROTEINS
    NIH K08CA079851May 1, 1999 - Apr 30, 2002
    Role: Principal Investigator

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    Collapse Clinical Trials

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Impact of Donor and Recipient Clinical Characteristics and Hepatic Histology on Steatosis/Fibrosis Following Liver Transplantation. Transplantation. 2022 01 01; 106(1):106-116. Shaked O, Demetris J, Levitsky J, Feng S, Loza BL, Punch J, Reyes J, Klintmalm G, Jackson W, DesMarais M, Sayre P, Shaked A, Reddy KR. PMID: 33982909; PMCID: PMC8349377.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    2. Inhibition of MET Signaling with Ficlatuzumab in Combination with Chemotherapy in Refractory AML: Clinical Outcomes and High-Dimensional Analysis. Blood Cancer Discov. 2021 09; 2(5):434-449. Wang VE, Blaser BW, Patel RK, Behbehani GK, Rao AA, Durbin-Johnson B, Jiang T, Logan AC, Settles M, Mannis GN, Olin R, Damon LE, Martin TG, Sayre PH, Gaensler KM, McMahon E, Flanders M, Weinberg V, Ye CJ, Carbone DP, Munster PN, Fragiadakis GK, McCormick F, Andreadis C. PMID: 34514432; PMCID: PMC8425277.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    3. Flotetuzumab as salvage immunotherapy for refractory acute myeloid leukemia. Blood. 2021 02 11; 137(6):751-762. Uy GL, Aldoss I, Foster MC, Sayre PH, Wieduwilt MJ, Advani AS, Godwin JE, Arellano ML, Sweet KL, Emadi A, Ravandi F, Erba HP, Byrne M, Michaelis L, Topp MS, Vey N, Ciceri F, Carrabba MG, Paolini S, Huls GA, Jongen-Lavrencic M, Wermke M, Chevallier P, Gyan E, Récher C, Stiff PJ, Pettit KM, Löwenberg B, Church SE, Anderson E, Vadakekolathu J, Santaguida M, Rettig MP, Muth J, Curtis T, Fehr E, Guo K, Zhao J, Bakkacha O, Jacobs K, Tran K, Kaminker P, Kostova M, Bonvini E, Walter RB, Davidson-Moncada JK, Rutella S, DiPersio JF. PMID: 32929488; PMCID: PMC7885824.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansCTClinical Trials
    4. Biomarkers of severity and threshold of allergic reactions during oral peanut challenges. J Allergy Clin Immunol. 2020 08; 146(2):344-355. Santos AF, Du Toit G, O'Rourke C, Becares N, Couto-Francisco N, Radulovic S, Khaleva E, Basting M, Harris KM, Larson D, Sayre P, Plaut M, Roberts G, Bahnson HT, Lack G. PMID: 32311390; PMCID: PMC7417812.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    5. Histone Deacetylase Inhibition with Panobinostat Combined with Intensive Induction Chemotherapy in Older Patients with Acute Myeloid Leukemia: Phase I Study Results. Clin Cancer Res. 2019 08 15; 25(16):4917-4923. Wieduwilt MJ, Pawlowska N, Thomas S, Olin R, Logan AC, Damon LE, Martin T, Kang M, Sayre PH, Boyer W, Gaensler KML, Anderson K, Munster PN, Andreadis C. PMID: 31152020.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCellsCTClinical Trials
    6. Association of Staphylococcus aureus colonization with food allergy occurs independently of eczema severity. J Allergy Clin Immunol. 2019 08; 144(2):494-503. Tsilochristou O, du Toit G, Sayre PH, Roberts G, Lawson K, Sever ML, Bahnson HT, Radulovic S, Basting M, Plaut M, Lack G, Immune Tolerance Network Learning Early About Peanut Allergy Study Team. PMID: 31160034.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    7. The MALT1 locus and peanut avoidance in the risk for peanut allergy. J Allergy Clin Immunol. 2019 06; 143(6):2326-2329. Winters A, Bahnson HT, Ruczinski I, Boorgula MP, Malley C, Keramati AR, Chavan S, Larson D, Cerosaletti K, Sayre PH, Plaut M, Du Toit G, Lack G, Barnes KC, Nepom GT, Mathias RA, Immune Tolerance Network LEAP Study Team. PMID: 30825465; PMCID: PMC6556406.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    8. Prevalence and Impact of De Novo Donor-Specific Antibodies During a Multicenter Immunosuppression Withdrawal Trial in Adult Liver Transplant Recipients. Hepatology. 2019 03; 69(3):1273-1286. Jucaud V, Shaked A, DesMarais M, Sayre P, Feng S, Levitsky J, Everly MJ. PMID: 30229989.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    9. Outcomes of immunosuppression minimization and withdrawal early after liver transplantation. Am J Transplant. 2019 05; 19(5):1397-1409. Shaked A, DesMarais MR, Kopetskie H, Feng S, Punch JD, Levitsky J, Reyes J, Klintmalm GB, Demetris AJ, Burrell BE, Priore A, Bridges ND, Sayre PH. PMID: 30506630; PMCID: PMC6482056.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    10. Quantification of regional aerosol deposition patterns as a function of aerodynamic particle size in rhesus macaques using PET/CT imaging. Inhal Toxicol. 2017 09; 29(11):506-515. Dabisch PA, Xu Z, Boydston JA, Solomon J, Bohannon JK, Yeager JJ, Taylor JR, Reeder RJ, Sayre P, Seidel J, Mollura DJ, Hevey MC, Jahrling PB, Lackemeyer MG. PMID: 29224407.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsPHPublic Health
    11. Allergen specificity of early peanut consumption and effect on development of allergic disease in the Learning Early About Peanut Allergy study cohort. J Allergy Clin Immunol. 2018 04; 141(4):1343-1353. du Toit G, Sayre PH, Roberts G, Lawson K, Sever ML, Bahnson HT, Fisher HR, Feeney M, Radulovic S, Basting M, Plaut M, Lack G, Immune Tolerance Network Learning Early About Peanut Allergy study team. PMID: 29097103; PMCID: PMC5889963.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    12. High-dose immunosuppressive therapy and autologous HCT for relapsing-remitting MS. Neurology. 2017 Feb 28; 88(9):842-852. Nash RA, Hutton GJ, Racke MK, Popat U, Devine SM, Steinmiller KC, Griffith LM, Muraro PA, Openshaw H, Sayre PH, Stuve O, Arnold DL, Wener MH, Georges GE, Wundes A, Kraft GH, Bowen JD. PMID: 28148635; PMCID: PMC5331868.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCTClinical Trials
    13. An ectopically expressed serum miRNA signature is prognostic, diagnostic, and biologically related to liver allograft rejection. Hepatology. 2017 01; 65(1):269-280. Shaked A, Chang BL, Barnes MR, Sayre P, Li YR, Asare S, DesMarais M, Holmes MV, Guettouche T, Keating BJ. PMID: 27533743.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    14. ACCLAIM: A randomized trial of abatacept (CTLA4-Ig) for relapsing-remitting multiple sclerosis. Mult Scler. 2017 Apr; 23(5):686-695. Khoury SJ, Rochon J, Ding L, Byron M, Ryker K, Tosta P, Gao W, Freedman MS, Arnold DL, Sayre PH, Smilek DE, ACCLAIM Study Group. PMID: 27481207; PMCID: PMC5288398.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    15. Impact of peanut consumption in the LEAP Study: Feasibility, growth, and nutrition. J Allergy Clin Immunol. 2016 Oct; 138(4):1108-1118. Feeney M, Du Toit G, Roberts G, Sayre PH, Lawson K, Bahnson HT, Sever ML, Radulovic S, Plaut M, Lack G, Immune Tolerance Network LEAP Study Team. PMID: 27297994; PMCID: PMC5056823.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    16. Effect of Avoidance on Peanut Allergy after Early Peanut Consumption. N Engl J Med. 2016 Apr 14; 374(15):1435-43. Du Toit G, Sayre PH, Roberts G, Sever ML, Lawson K, Bahnson HT, Brough HA, Santos AF, Harris KM, Radulovic S, Basting M, Turcanu V, Plaut M, Lack G, Immune Tolerance Network LEAP-On Study Team. PMID: 26942922.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimals
    17. Quantification of Acute Lymphoblastic Leukemia Clonotypes in Leukapheresed Peripheral Blood Progenitor Cells Predicts Relapse Risk after Autologous Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2016 06; 22(6):1030-1036. Mannis GN, Martin TG, Damon LE, Andreadis C, Olin RL, Kong KA, Faham M, Hwang J, Ai WZ, Gaensler KML, Sayre PH, Wolf JL, Logan AC. PMID: 26899561.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    18. Long-term outcomes of patients with intermediate-risk acute myeloid leukemia treated with autologous hematopoietic cell transplant in first complete remission. Leuk Lymphoma. 2016 07; 57(7):1560-6. Mannis GN, Martin TG, Damon LE, Logan AC, Olin RL, Flanders MD, Ai WZ, Gaensler KM, Kaplan LD, Sayre PH, Smith CC, Wolf JL, Andreadis C. PMID: 26490487.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Type 1 diabetes immunotherapy using polyclonal regulatory T cells. Sci Transl Med. 2015 Nov 25; 7(315):315ra189. Bluestone JA, Buckner JH, Fitch M, Gitelman SE, Gupta S, Hellerstein MK, Herold KC, Lares A, Lee MR, Li K, Liu W, Long SA, Masiello LM, Nguyen V, Putnam AL, Rieck M, Sayre PH, Tang Q. PMID: 26606968; PMCID: PMC4729454.
      View in: PubMed   Mentions: 508     Fields:    Translation:HumansCellsCTClinical Trials
    20. Long-Term Follow-Up of the Edmonton Protocol of Islet Transplantation in the United States. Am J Transplant. 2016 Feb; 16(2):509-17. Brennan DC, Kopetskie HA, Sayre PH, Alejandro R, Cagliero E, Shapiro AM, Goldstein JS, DesMarais MR, Booher S, Bianchine PJ. PMID: 26433206.
      View in: PubMed   Mentions: 68     Fields:    Translation:Humans
    21. Peanut consumption in infants at risk for peanut allergy. N Engl J Med. 2015 05 28; 372(22):2165. Lack G, Plaut M, Sayre PH. PMID: 26017828.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    22. Randomized trial of peanut consumption in infants at risk for peanut allergy. N Engl J Med. 2015 Feb 26; 372(9):803-13. Du Toit G, Roberts G, Sayre PH, Bahnson HT, Radulovic S, Santos AF, Brough HA, Phippard D, Basting M, Feeney M, Turcanu V, Sever ML, Gomez Lorenzo M, Plaut M, Lack G, LEAP Study Team. PMID: 25705822; PMCID: PMC4416404.
      View in: PubMed   Mentions: 602     Fields:    Translation:HumansAnimals
    23. A phase I study of targeted, dose-escalated intravenous busulfan in combination with etoposide as myeloablative therapy for autologous stem cell transplantation in acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2015 Jun; 15(6):377-83. Mannis GN, Andreadis C, Logan AC, Damon LE, Benet LZ, Ai WZ, Gaensler KM, Kaplan LD, Koplowicz YB, Linker CA, Olin RL, Sayre PH, Smith CC, Sudhindra A, Venstrom JM, Wolf JL, Martin TG. PMID: 25776193.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    24. High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for relapsing-remitting multiple sclerosis (HALT-MS): a 3-year interim report. JAMA Neurol. 2015 Feb; 72(2):159-69. Nash RA, Hutton GJ, Racke MK, Popat U, Devine SM, Griffith LM, Muraro PA, Openshaw H, Sayre PH, Stüve O, Arnold DL, Spychala ME, McConville KC, Harris KM, Phippard D, Georges GE, Wundes A, Kraft GH, Bowen JD. PMID: 25546364; PMCID: PMC5261862.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCTClinical Trials
    25. Delayed hematopoietic recovery after auto-SCT in patients receiving arsenic trioxide-based therapy for acute promyelocytic leukemia: a multi-center analysis. Bone Marrow Transplant. 2015 Jan; 50(1):40-4. Mannis GN, Logan AC, Leavitt AD, Yanada M, Hwang J, Olin RL, Damon LE, Andreadis C, Ai WZ, Gaensler KM, Greene CC, Gupta NK, Kaplan LD, Mahindra A, Miyazaki Y, Naoe T, Ohtake S, Sayre PH, Smith CC, Venstrom JM, Wolf JL, Caballero L, Emi N, Martin TG. PMID: 25243620.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    26. Long-term results in recipients of combined HLA-mismatched kidney and bone marrow transplantation without maintenance immunosuppression. Am J Transplant. 2014 Jul; 14(7):1599-611. Kawai T, Sachs DH, Sprangers B, Spitzer TR, Saidman SL, Zorn E, Tolkoff-Rubin N, Preffer F, Crisalli K, Gao B, Wong W, Morris H, LoCascio SA, Sayre P, Shonts B, Williams WW, Smith RN, Colvin RB, Sykes M, Cosimi AB. PMID: 24903438; PMCID: PMC4228952.
      View in: PubMed   Mentions: 120     Fields:    Translation:Humans
    27. Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial. Lancet Diabetes Endocrinol. 2013 Dec; 1(4):306-16. Gitelman SE, Gottlieb PA, Rigby MR, Felner EI, Willi SM, Fisher LK, Moran A, Gottschalk M, Moore WV, Pinckney A, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, Ding L, Bluestone JA, Ehlers MR, START Study Team. PMID: 24622416; PMCID: PMC6489466.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCTClinical Trials
    28. Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: metabolic and immunologic features at baseline identify a subgroup of responders. Diabetes. 2013 Nov; 62(11):3766-74. Herold KC, Gitelman SE, Ehlers MR, Gottlieb PA, Greenbaum CJ, Hagopian W, Boyle KD, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, McNamara J, Bluestone JA, AbATE Study Team. PMID: 23835333; PMCID: PMC3806618.
      View in: PubMed   Mentions: 175     Fields:    Translation:Humans
    29. Prophylactic use of sublingual allergen immunotherapy in high-risk children: a pilot study. J Allergy Clin Immunol. 2013 Oct; 132(4):991-3.e1. Holt PG, Sly PD, Sampson HA, Robinson P, Loh R, Lowenstein H, Calatroni A, Sayre P. PMID: 23768574.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    30. Identifying infants at high risk of peanut allergy: the Learning Early About Peanut Allergy (LEAP) screening study. J Allergy Clin Immunol. 2013 Jan; 131(1):135-43.e1-12. Du Toit G, Roberts G, Sayre PH, Plaut M, Bahnson HT, Mitchell H, Radulovic S, Chan S, Fox A, Turcanu V, Lack G, Learning Early About Peanut Allergy (LEAP) Study Team. PMID: 23174658.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimals
    31. Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy. J Autoimmun. 2010 Jun; 34(4):408-15. Orban T, Farkas K, Jalahej H, Kis J, Treszl A, Falk B, Reijonen H, Wolfsdorf J, Ricker A, Matthews JB, Tchao N, Sayre P, Bianchine P. PMID: 19931408; PMCID: PMC2860016.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    32. Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb Teplizumab preserves insulin production for up to 5 years. Clin Immunol. 2009 Aug; 132(2):166-73. Herold KC, Gitelman S, Greenbaum C, Puck J, Hagopian W, Gottlieb P, Sayre P, Bianchine P, Wong E, Seyfert-Margolis V, Bourcier K, Bluestone JA, Immune Tolerance Network ITN007AI Study Group. PMID: 19443276; PMCID: PMC2735402.
      View in: PubMed   Mentions: 93     Fields:    Translation:Humans
    33. Multi-targeted antifolates aimed at avoiding drug resistance form covalent closed inhibitory complexes with human and Escherichia coli thymidylate synthases. J Mol Biol. 2001 Nov 02; 313(4):813-29. Sayre PH, Finer-Moore JS, Fritz TA, Biermann D, Gates SB, MacKellar WC, Patel VF, Stroud RM. PMID: 11697906.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    34. Enzyme-catalyzed therapeutic agent (ECTA) design: activation of the antitumor ECTA compound NB1011 by thymidylate synthase. Biochem Pharmacol. 2001 Jan 15; 61(2):179-89. Lackey DB, Groziak MP, Sergeeva M, Beryt M, Boyer C, Stroud RM, Sayre P, Park JW, Johnston P, Slamon D, Shepard HM, Pegram M. PMID: 11163332.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    35. Autologous stem cell transplantation for acute myeloid leukemia in first remission. Biol Blood Marrow Transplant. 2000; 6(1):50-7. Linker CA, Ries CA, Damon LE, Sayre P, Navarro W, Rugo HS, Rubin A, Case D, Crilley P, Topolsky D, Brodsky I, Zamkoff K, Wolfe JL. PMID: 10707999.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    36. ESX: a structurally unique Ets overexpressed early during human breast tumorigenesis. Oncogene. 1997 Apr 03; 14(13):1617-22. Chang CH, Scott GK, Kuo WL, Xiong X, Suzdaltseva Y, Park JW, Sayre P, Erny K, Collins C, Gray JW, Benz CC. PMID: 9129154.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
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