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Philippe Depeille, PhD

Title(s)Specialist, Anatomy
SchoolSchool of Medicine
Address513 Parnassus Ave, HSW
San Francisco CA 94143
Phone415-476-4322
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo. Cell Stem Cell. 2020 Aug 14. Miao Y, Ha A, de Lau W, Yuki K, Santos AJM, You C, Geurts MH, Puschhof J, Pleguezuelos-Manzano C, Peng WC, Senlice R, Piani C, Buikema JW, Gbenedio OM, Vallon M, Yuan J, de Haan S, Hemrika W, Rösch K, Dang LT, Baker D, Ott M, Depeille P, Wu SM, Drost J, Nusse R, Roose JP, Piehler J, Boj SF, Janda CY, Clevers H, Kuo CJ, Garcia KC. PMID: 32818433.
      View in: PubMed   Mentions:    Fields:    
    2. RasGRP1 is a potential biomarker to stratify anti-EGFR therapy response in colorectal cancer. JCI Insight. 2019 06 25; 5. Gbenedio OM, Bonnans C, Grun D, Wang CY, Hatch AJ, Mahoney MR, Barras D, Matli M, Miao Y, Garcia KC, Tejpar S, Delorenzi M, Venook AP, Nixon AB, Warren RS, Roose JP, Depeille P. PMID: 31237864.
      View in: PubMed   Mentions: 1     Fields:    
    3. RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma. Cancer Cell. 2017 05 08; 31(5):685-696.e6. Chen X, Wu Q, Depeille P, Chen P, Thornton S, Kalirai H, Coupland SE, Roose JP, Bastian BC. PMID: 28486107.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    4. Suppressive signals in colorectal cancer: RasGRP1 a new marker for anti-EGFR therapy?. Journal of Clinical Oncology. 2016 Feb 1; 34(4_suppl):625-625. Jeroen Roose, Philippe Depeille, Robert S. Warren. .
      View in: Publisher Site   Mentions:
    5. Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome. J Neurosci. 2016 Jan 06; 36(1):142-52. Rooney GE, Goodwin AF, Depeille P, Sharir A, Schofield CM, Yeh E, Roose JP, Klein OD, Rauen KA, Weiss LA, Ullian EM. PMID: 26740656.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    6. Unexpected insights for anti-EGFR cancer therapy. Oncotarget. 2015 Aug 07; 6(22):18746-7. Depeille P, Warren RS, Roose JP. PMID: 26300054.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    7. RasGRP1 opposes proliferative EGFR-SOS1-Ras signals and restricts intestinal epithelial cell growth. Nat Cell Biol. 2015 Jun; 17(6):804-15. Depeille P, Henricks LM, van de Ven RA, Lemmens E, Wang CY, Matli M, Werb Z, Haigis KM, Donner D, Warren R, Roose JP. PMID: 26005835.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    8. Flavors of EGFR-Ras signals impacting intestinal homeostasis. Cell Cycle. 2015; 14(20):3205-6. Depeille P, Roose JP. PMID: 26292152.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    9. PLC-? and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras. Sci Signal. 2013 Dec 03; 6(304):ra105. Diaz-Flores E, Goldschmidt H, Depeille P, Ng V, Akutagawa J, Krisman K, Crone M, Burgess MR, Williams O, Houseman B, Shokat K, Sampath D, Bollag G, Roose JP, Braun BS, Shannon K. PMID: 24300897.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    10. Abstract B1: Dual mTORC1/mTORC2 inhibition limits tumor growth, VEGF production and vascular regrowth. Clinical Cancer Research. 2012 May 15; 18(10_Supplement):b1-b1. S. Barr, B. L. Falcon, P. C. Ghokale, J. Chou, J. Fogarty, P. Depeille, M. Miglarese, D. M. Epstein. .
      View in: Publisher Site   Mentions:
    11. STIM1, PKC-d and RasGRP set a threshold for proapoptotic Erk signaling during B cell development. Nat Immunol. 2011 May; 12(5):425-33. Limnander A, Depeille P, Freedman TS, Liou J, Leitges M, Kurosaki T, Roose JP, Weiss A. PMID: 21441934.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    12. Reduced VEGF production, angiogenesis, and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors. Cancer Res. 2011 Mar 01; 71(5):1573-83. Falcon BL, Barr S, Gokhale PC, Chou J, Fogarty J, Depeille P, Miglarese M, Epstein DM, McDonald DM. PMID: 21363918.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    13. PI3 Kinase, Phospholipase C (PLC)-?, and RasGRPs Act Cooperatively to Activate the Ras-Extracellular-Related Kinase (ERK) Pathway in Response to Cytokines in Normal and Kras Mutant Myeloid Cells. Blood. 2009 Nov 20; 114(22):2512-2512. Ernesto Diaz-Flores, Hana Leah Goldschmidt, Philippe Depeille, Victor Ng, Jeroen Roose, Kevan Shokat, Benjamin S. Braun, Kevin Shannon. .
      View in: Publisher Site   Mentions:
    14. Anthrax lethal toxin inhibits growth of and vascular endothelial growth factor release from endothelial cells expressing the human herpes virus 8 viral G protein coupled receptor. Clin Cancer Res. 2007 Oct 01; 13(19):5926-34. Depeille P, Young JJ, Boguslawski EA, Berghuis BD, Kort EJ, Resau JH, Frankel AE, Duesbery NS. PMID: 17908989.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    15. MKK signaling and vascularization. Oncogene. 2007 Feb 26; 26(9):1290-6. Depeille PE, Ding Y, Bromberg-White JL, Duesbery NS. PMID: 17322914.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    16. O(6)-methylguanine DNA-methyltransferase (MGMT) overexpression in melanoma cells induces resistance to nitrosoureas and temozolomide but sensitizes to mitomycin C. Toxicol Appl Pharmacol. 2006 Mar 01; 211(2):97-105. Passagne I, Evrard A, Depeille P, Cuq P, Cupissol D, Vian L. PMID: 16039682.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    17. Glutathione S-transferase M1 and multidrug resistance protein 1 act in synergy to protect melanoma cells from vincristine effects. Mol Pharmacol. 2004 Apr; 65(4):897-905. Depeille P, Cuq P, Mary S, Passagne I, Evrard A, Cupissol D, Vian L. PMID: 15044619.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    18. Cytotoxicity, DNA damage, and apoptosis induced by new fotemustine analogs on human melanoma cells in relation to O6-methylguanine DNA-methyltransferase expression. J Pharmacol Exp Ther. 2003 Nov; 307(2):816-23. Passagne I, Evrard A, Winum JY, Depeille P, Cuq P, Montero JL, Cupissol D, Vian L. PMID: 12970393.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
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