Prabhakar Bastola, PhD

Title(s)Postdoctoral Scholar, Laboratory Medicine
SchoolSchool of Medicine
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    1. Bastola P, Bilkis R, De Souza C, Minn K, Chien J. Heterozygous mutations in valosin-containing protein (VCP) and resistance to VCP inhibitors. Sci Rep. 2019 Jul 29; 9(1):11002. PMID: 31358864.
      View in: PubMed
    2. Bastola P, Oien DB, Cooley M, Chien J. Emerging Cancer Therapeutic Targets in Protein Homeostasis. AAPS J. 2018 Aug 27; 20(6):94. PMID: 30151644.
      View in: PubMed
    3. Bastola P, Chien J. Co-selected mutations in VCP: a novel mechanism of resistance to VCP inhibitors. Cell Death Dis. 2018 01 18; 9(2):35. PMID: 29348605.
      View in: PubMed
    4. Bastola P, Wang F, Schaich MA, Gan T, Freudenthal BD, Chou TF, Chien J. Specific mutations in the D1-D2 linker region of VCP/p97 enhance ATPase activity and confer resistance to VCP inhibitors. Cell Death Discov. 2017; 3:17065. PMID: 29367883.
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    5. Bastola P, Neums L, Schoenen FJ, Chien J. VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase-mediated cell death and synergistically kill ovarian cancer cells in combination with Salubrinal. Mol Oncol. 2016 12; 10(10):1559-1574. PMID: 27729194.
      View in: PubMed