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Priscilla Hsue, MD

TitleProfessor
SchoolUCSF School of Medicine
DepartmentMedicine
Address1001 Potrero Ave
San Francisco CA 94110
Phone415-206-8257
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoCert2006 Medicine (Advance Training in Clinical Research)
    University of California, San Francisco Clinical Fellowship School of Medicine
    University of California, San Francisco Residency School of Medicine
    University of California, San FranciscoM.D.1996 Medicine

    Collapse Overview 
    Collapse Overview
    Professional Experience: Dr. Hsue trained in Internal Medicine in the Molecular Medicine Training Program at UC San Francisco and in Cardiovascular Medicine at UC San Francisco. She served as Chief Cardiology Fellow during this time. She has been on the faculty in the Department of Medicine at San Francisco General Hospital since 2002. She started the HIV Cardiology Clinic since March 2004 at the Positive Health Program at Ward 86, which is one of the first subspeciality clinics of its kind in the nation.

    Research Interests:
    - Cardiovascular complications of cocaine including aortic dissection, myocardial infarction, and cardiac arrest
    - Pathogenesis of atherosclerosis in HIV-infected patients treated with antiretroviral therapy
    - Clinical features and outcomes of acute coronary syndromes in HIV-infected patients
    - Incidence and mechanisms of pulmonary hypertension in HIV-infected patients
    - Dyslipidemia in HIV-infected patients


    Collapse Research 
    Collapse Research Activities and Funding
    Protein Biomarkers for CVD Prediction in HIV-Infected and Uninfected Veterans
    NIH/NHLBI R01HL129856Sep 1, 2016 - Jun 30, 2020
    Role: Principal Investigator
    Effect of IL-1B inhibition on inflammation and cardiovascular risk in HIV
    NIH/NHLBI R01HL125034Apr 1, 2015 - Aug 31, 2018
    Role: Principal Investigator
    Effect of IL-1B inhibition on inflammation and cardiovascular risk in HIV
    NIH/NHLBI R56HL125034Sep 11, 2014 - Aug 31, 2015
    Role: Principal Investigator
    HIV Viral Reservoirs and Monocyte Activation in HIV-Associated Atherosclerosis
    NIH/NIAID K24AI112393Mar 1, 2014 - Feb 28, 2019
    Role: Principal Investigator
    Genotypic and functional properties of HIV-1 Nef clinical isolates in PAH-HIV
    NIH/NHLBI U01HL121819Sep 26, 2013 - Jul 31, 2018
    Role: Co-Principal Investigator
    Effect of low dose methotrexate on endothelial function and inflammation in HIV
    NIH/NHLBI R01HL117713Sep 26, 2012 - Apr 30, 2017
    Role: Principal Investigator
    Inflammation, Viral Replication, and Atherosclerosis in Treated HIV Infection
    NIH/NHLBI R01HL095130Sep 25, 2008 - Jun 30, 2014
    Role: Principal Investigator
    Epidemiology and Pathogenesis of Pulmonary Hypertension in HIV Patients
    NIH/NHLBI R01HL091526Sep 16, 2007 - Jul 31, 2013
    Role: Principal Investigator
    Pathogenesis of Atherosclerosis in HIV Patients on HAART
    NIH/NIAID K23AI066885Jul 15, 2005 - May 31, 2010
    Role: Principal Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000083Oct 1, 1974 - Nov 30, 2007
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News
    Collapse Clinical Trials
    Collapse Global Health

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Gallant J, Hsue P, Budd D, Meyer N. Healthcare utilization and direct costs of non-infectious comorbidities in HIV-infected patients in the USA. Curr Med Res Opin. 2017 Sep 21; 1-15. PMID: 28933204.
      View in: PubMed
    2. Chau KH, Scherzer R, Grunfeld C, Hsue P, Shlipak MG. CHA2DS2-VASc Score, Warfarin Use, and Risk for Thromboembolic Events Among HIV-Infected Persons With Atrial Fibrillation. J Acquir Immune Defic Syndr. 2017 Sep 01; 76(1):90-97. PMID: 28797024.
      View in: PubMed
    3. Hsue P, Waters DD. Heart failure in persons living with HIV infection. Curr Opin HIV AIDS. 2017 Aug 31. PMID: 28863015.
      View in: PubMed
    4. Phan BAP, Weigel B, Ma Y, Scherzer R, Li D, Hur S, Kalapus SC, Deeks S, Hsue P. Utility of 2013 American College of Cardiology/American Heart Association Cholesterol Guidelines in HIV-Infected Adults With Carotid Atherosclerosis. Circ Cardiovasc Imaging. 2017 Jul; 10(7). PMID: 28674084.
      View in: PubMed
    5. Waters DD, Hsue P. PCSK9 Inhibition to Reduce Cardiovascular Risk: Tempering Expectations. Circ Res. 2017 May 12; 120(10):1537-1539. PMID: 28495986.
      View in: PubMed
    6. Chen R, Scherzer R, Hsue P, Jotwani V, Estrella MM, Horberg MA, Grunfeld C, Shlipak MG. Association of Tenofovir Use With Risk of Incident Heart Failure in HIV-Infected Patients. J Am Heart Assoc. 2017 Apr 24; 6(4). PMID: 28438737.
      View in: PubMed
    7. Chow FC, Price RW, Hsue P, Kim AS. Greater Risk of Stroke of Undetermined Etiology in a Contemporary HIV-Infected Cohort Compared with Uninfected Individuals. J Stroke Cerebrovasc Dis. 2017 May; 26(5):1154-1160. PMID: 28262563.
      View in: PubMed
    8. Tawakol A, Ishai A, Li D, Takx RA, Hur S, Kaiser Y, Pampaloni M, Rupert A, Hsu D, Sereti I, Fromentin R, Chomont N, Ganz P, Deeks SG, Hsue P. Association of Arterial and Lymph Node Inflammation With Distinct Inflammatory Pathways in Human Immunodeficiency Virus Infection. JAMA Cardiol. 2017 Feb 01; 2(2):163-171. PMID: 27926762.
      View in: PubMed
    9. Riley ED, Hsue P, Vittinghoff E, Wu AH, Coffin PO, Moore PK, Lynch KL. Higher prevalence of detectable troponin I among cocaine-users without known cardiovascular disease. Drug Alcohol Depend. 2017 Mar 01; 172:88-93. PMID: 28157591.
      View in: PubMed
    10. Sinha A, Ma Y, Scherzer R, Hur S, Li D, Ganz P, Deeks SG, Hsue P. Role of T-Cell Dysfunction, Inflammation, and Coagulation in Microvascular Disease in HIV. J Am Heart Assoc. 2016 Dec 20; 5(12). PMID: 27998918.
      View in: PubMed
    11. Hsu DC, Ma YF, Hur S, Li D, Rupert A, Scherzer R, Kalapus SC, Deeks S, Sereti I, Hsue P. Plasma IL-6 levels are independently associated with atherosclerosis and mortality in HIV-infected individuals on suppressive antiretroviral therapy. AIDS. 2016 Aug 24; 30(13):2065-74. PMID: 27177313.
      View in: PubMed
    12. Bertero T, Oldham WM, Cottrill KA, Pisano S, Vanderpool RR, Yu Q, Zhao J, Tai Y, Tang Y, Zhang YY, Rehman S, Sugahara M, Qi Z, Gorcsan J, Vargas SO, Saggar R, Saggar R, Wallace WD, Ross DJ, Haley KJ, Waxman AB, Parikh VN, De Marco T, Hsue P, Morris A, Simon MA, Norris KA, Gaggioli C, Loscalzo J, Fessel J, Chan SY. Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension. J Clin Invest. 2016 Sep 01; 126(9):3313-35. PMID: 27548520; PMCID: PMC5004943 [Available on 12/01/16].
    13. Stein JH, Hsue P. Inflammation and Arterial Injury in Individuals With Human Immunodeficiency Virus Infection. JAMA Cardiol. 2016 Jul 01; 1(4):481-2. PMID: 27438326.
      View in: PubMed
    14. Ramirez CM, Sinclair E, Epling L, Lee SA, Jain V, Hsue P, Hatano H, Conn D, Hecht FM, Martin JN, Mccune JM, Deeks SG, Hunt PW. Immunologic profiles distinguish aviremic HIV-infected adults. AIDS. 2016 Jun 19; 30(10):1553-62. PMID: 26854811.
      View in: PubMed
    15. Kohli P, Ganz P, Ma Y, Scherzer R, Hur S, Weigel B, Grunfeld C, Deeks S, Wasserman S, Scott R, Hsue P. HIV and Hepatitis C-Coinfected Patients Have Lower Low-Density Lipoprotein Cholesterol Despite Higher Proprotein Convertase Subtilisin Kexin 9 (PCSK9): An Apparent "PCSK9-Lipid Paradox". J Am Heart Assoc. 2016 Apr 29; 5(5). PMID: 27130349; PMCID: PMC4889164.
    16. Waters DD, Hsue P, Bangalore S. PCSK9 Inhibitors for Statin Intolerance? JAMA. 2016 Apr 19; 315(15):1571-2. PMID: 27039138.
      View in: PubMed
    17. Hsue P, Tawakol A. Inflammation and Fibrosis in HIV: Getting to the Heart of the Matter. Circ Cardiovasc Imaging. 2016 Mar; 9(3):e004427. PMID: 26951604.
      View in: PubMed
    18. Parikh RV, Ma Y, Scherzer R, Heringer AS, Macgregor JS, Martin JN, Deeks SG, Ganz P, Hsue P. Endothelin-1 Predicts Hemodynamically Assessed Pulmonary Arterial Hypertension in HIV Infection. PLoS One. 2016; 11(1):e0146355. PMID: 26752193; PMCID: PMC4709102.
    19. Chow FC, Boscardin WJ, Mills C, Ko N, Carroll C, Price RW, Deeks S, Sorond FA, Hsue P. Cerebral vasoreactivity is impaired in treated, virally suppressed HIV-infected individuals. AIDS. 2016 Jan 02; 30(1):45-55. PMID: 26372478; PMCID: PMC4703496 [Available on 01/02/17].
    20. Feinstein MJ, Bahiru E, Achenbach C, Longenecker CT, Hsue P, So-Armah K, Freiberg MS, Lloyd-Jones DM. Patterns of Cardiovascular Mortality for HIV-Infected Adults in the United States: 1999 to 2013. Am J Cardiol. 2016 Jan 15; 117(2):214-20. PMID: 26639041.
      View in: PubMed
    21. Parikh VN, Park J, Nikolic I, Channick R, Yu PB, De Marco T, Hsue P, Chan SY. Brief Report: Coordinated Modulation of Circulating miR-21 in HIV, HIV-Associated Pulmonary Arterial Hypertension, and HIV/Hepatitis C Virus Coinfection. J Acquir Immune Defic Syndr. 2015 Nov 01; 70(3):236-41. PMID: 26473639; PMCID: PMC4610144 [Available on 11/01/16].
    22. Secemsky EA, Scherzer R, Nitta E, Wu AH, Lange DC, Deeks SG, Martin JN, Snider J, Ganz P, Hsue P. Novel Biomarkers of Cardiac Stress, Cardiovascular Dysfunction, and Outcomes in HIV-Infected Individuals. JACC Heart Fail. 2015 Aug; 3(8):591-9. PMID: 26164679; PMCID: PMC4529774.
    23. Lange DC, Glidden D, Secemsky EA, Ordovas K, Deeks SG, Martin JN, Bolger AF, Hsue P. Mitral Annular and Coronary Artery Calcification Are Associated with Mortality in HIV-Infected Individuals. PLoS One. 2015; 10(7):e0130592. PMID: 26132465; PMCID: PMC4488486.
    24. Waters DD, Hsue P. PCSK9 Inhibition to Lower LDL-Cholesterol and Reduce Cardiovascular Risk: Great Expectations. Circ Res. 2015 May 08; 116(10):1643-5. PMID: 25953922.
      View in: PubMed
    25. Waldo SW, Brenner DA, McCabe JM, Cruz MD, Long B, Narla VA, Park J, Kulkarni A, Sinclair E, Chan SY, Schick SF, Malik N, Ganz P, Hsue P. Correction: A novel minimally-invasive method to sample human endothelial cells for molecular profiling. PLoS One. 2015; 10(5):e0126062. PMID: 25938419; PMCID: PMC4418848.
    26. Shah MR, Cook N, Wong R, Hsue P, Ridker P, Currier J, Shurin S. Stimulating high impact HIV-related cardiovascular research: recommendations from a multidisciplinary NHLBI Working Group on HIV-related heart, lung, and blood disease. J Am Coll Cardiol. 2015 Feb 24; 65(7):738-44. PMID: 25677433; PMCID: PMC4330466.
    27. Waldo SW, Brenner DA, McCabe JM, Dela Cruz M, Long B, Narla VA, Park J, Kulkarni A, Sinclair E, Chan SY, Schick SF, Malik N, Ganz P, Hsue P. A novel minimally-invasive method to sample human endothelial cells for molecular profiling. PLoS One. 2015; 10(2):e0118081. PMID: 25679506; PMCID: PMC4332500.
    28. Somsouk M, Dunham RM, Cohen M, Albright R, Abdel-Mohsen M, Liegler T, Lifson J, Piatak M, Gorelick R, Huang Y, Wu Y, Hsue P, Martin JN, Deeks SG, McCune JM, Hunt PW. The immunologic effects of mesalamine in treated HIV-infected individuals with incomplete CD4+ T cell recovery: a randomized crossover trial. PLoS One. 2014; 9(12):e116306. PMID: 25545673; PMCID: PMC4283685.
    29. Hsue P, Bittner VA, Betteridge J, Fayyad R, Laskey R, Wenger NK, Waters DD. Impact of female sex on lipid lowering, clinical outcomes, and adverse effects in atorvastatin trials. Am J Cardiol. 2015 Feb 15; 115(4):447-53. PMID: 25637322.
      View in: PubMed
    30. Chow FC, Bacchetti P, Kim AS, Price RW, Hsue P. Effect of CD4+ cell count and viral suppression on risk of ischemic stroke in HIV infection. AIDS. 2014 Nov 13; 28(17):2573-7. PMID: 25160935; PMCID: PMC4743753.
    31. Hsue P, Scherzer R, Grunfeld C, Imboden J, Wu Y, Del Puerto G, Nitta E, Shigenaga J, Schnell Heringer A, Ganz P, Graf J. Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis. J Am Heart Assoc. 2014 Oct 21; 3(5):e001267. PMID: 25336464; PMCID: PMC4323827.
    32. Crane HM, Heckbert SR, Drozd DR, Budoff MJ, Delaney JA, Rodriguez C, Paramsothy P, Lober WB, Burkholder G, Willig JH, Mugavero MJ, Mathews WC, Crane PK, Moore RD, Napravnik S, Eron JJ, Hunt P, Geng E, Hsue P, Barnes GS, McReynolds J, Peter I, Grunfeld C, Saag MS, Kitahata MM. The authors reply. Am J Epidemiol. 2014 Aug 15; 180(4):450. PMID: 24989243; PMCID: PMC4809980.
    33. Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue P, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, Huang Y, Hecht FM, Martin JN, McCune JM, Moreno S, Deeks SG. HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality. PLoS Pathog. 2014 May; 10(5):e1004078. PMID: 24831517; PMCID: PMC4022662.
    34. Stein JH, Currier JS, Hsue P. Arterial disease in patients with human immunodeficiency virus infection: what has imaging taught us? JACC Cardiovasc Imaging. 2014 May; 7(5):515-25. PMID: 24831212; PMCID: PMC4024182.
    35. Crane HM, Heckbert SR, Drozd DR, Budoff MJ, Delaney JA, Rodriguez C, Paramsothy P, Lober WB, Burkholder G, Willig JH, Mugavero MJ, Mathews WC, Crane PK, Moore RD, Napravnik S, Eron JJ, Hunt P, Geng E, Hsue P, Barnes GS, McReynolds J, Peter I, Grunfeld C, Saag MS, Kitahata MM. Lessons learned from the design and implementation of myocardial infarction adjudication tailored for HIV clinical cohorts. Am J Epidemiol. 2014 Apr 15; 179(8):996-1005. PMID: 24618065; PMCID: PMC3966717.
    36. Lee SA, Sinclair E, Hatano H, Hsue P, Epling L, Hecht FM, Bangsberg DR, Martin JN, McCune JM, Deeks SG, Hunt PW. Impact of HIV on CD8+ T cell CD57 expression is distinct from that of CMV and aging. PLoS One. 2014; 9(2):e89444. PMID: 24586783; PMCID: PMC3937334.
    37. Parikh RV, Scherzer R, Nitta EM, Leone A, Hur S, Mistry V, Macgregor JS, Martin JN, Deeks SG, Ganz P, Hsue P. Increased levels of asymmetric dimethylarginine are associated with pulmonary arterial hypertension in HIV infection. AIDS. 2014 Feb 20; 28(4):511-9. PMID: 24469026; PMCID: PMC4149286.
    38. Moyers BS, Secemsky EA, Vittinghoff E, Wong JK, Havlir DV, Hsue P, Tseng ZH. Effect of left ventricular dysfunction and viral load on risk of sudden cardiac death in patients with human immunodeficiency virus. Am J Cardiol. 2014 Apr 01; 113(7):1260-5. PMID: 24521717; PMCID: PMC3959566.
    39. Hatano H, Bacchetti P, Hsue P, Deeks SG. Reply to Karch et al. J Infect Dis. 2014 Jul 01; 210(1):159-60. PMID: 24421253; PMCID: PMC4161999.
    40. McCabe JM, Armstrong EJ, Ku I, Kulkarni A, Hoffmayer KS, Bhave PD, Waldo SW, Hsue P, Stein JC, Marcus GM, Kinlay S, Ganz P. Physician accuracy in interpreting potential ST-segment elevation myocardial infarction electrocardiograms. J Am Heart Assoc. 2013 Oct 04; 2(5):e000268. PMID: 24096575; PMCID: PMC3835230.
    41. Armah KA, Chang CC, Baker JV, Ramachandran VS, Budoff MJ, Crane HM, Gibert CL, Goetz MB, Leaf DA, McGinnis KA, Oursler KK, Rimland D, Rodriguez-Barradas MC, Sico JJ, Warner AL, Hsue P, Kuller LH, Justice AC, Freiberg MS. Prehypertension, hypertension, and the risk of acute myocardial infarction in HIV-infected and -uninfected veterans. Clin Infect Dis. 2014 Jan; 58(1):121-9. PMID: 24065316; PMCID: PMC3864500.
    42. Turner TE, Waldo SW, Kulkarni A, Armstrong EJ, Hoffmayer KS, Kinlay S, Hsue P, Ganz P, McCabe JM. Long-term outcomes of patients sent emergently to the catheterization laboratory for possible primary percutaneous coronary intervention. Am J Cardiol. 2013 Dec 01; 112(11):1745-9. PMID: 24063836.
      View in: PubMed
    43. Hatano H, Strain MC, Scherzer R, Bacchetti P, Wentworth D, Hoh R, Martin JN, McCune JM, Neaton JD, Tracy RP, Hsue P, Richman DD, Deeks SG. Increase in 2-long terminal repeat circles and decrease in D-dimer after raltegravir intensification in patients with treated HIV infection: a randomized, placebo-controlled trial. J Infect Dis. 2013 Nov 01; 208(9):1436-42. PMID: 23975885; PMCID: PMC3789577.
    44. Waldo SW, Armstrong EJ, Kulkarni A, Hoffmayer KS, Hsue P, Ganz P, McCabe JM. Clinical characteristics and reperfusion times among patients with an isolated posterior myocardial infarction. J Invasive Cardiol. 2013 Aug; 25(8):371-5. PMID: 23913600.
      View in: PubMed
    45. Brenner DA, Dela Cruz M, Thomas K, McCabe JM, Ganz P, Hsue P, Waldo SW. Emergency medical service utilization and door-to-balloon time for HIV-infected individuals with ST-elevation myocardial infarction. Int J Cardiol. 2013 Oct 12; 168(5):4808-9. PMID: 23871355.
      View in: PubMed
    46. Ganz P, Hsue P. Endothelial dysfunction in coronary heart disease is more than a systemic process. Eur Heart J. 2013 Jul; 34(27):2025-7. PMID: 23756335.
      View in: PubMed
    47. Parikh RV, Scherzer R, Grunfeld C, Nitta EM, Leone A, Martin JN, Deeks SG, Ganz P, Hsue P. Elevated levels of asymmetric dimethylarginine are associated with lower CD4+ count and higher viral load in HIV-infected individuals. Atherosclerosis. 2013 Jul; 229(1):246-52. PMID: 23711612; PMCID: PMC3691342.
    48. Barnett CF, Hsue P. Human immunodeficiency virus-associated pulmonary arterial hypertension. Clin Chest Med. 2013 Jun; 34(2):283-92. PMID: 23702177; PMCID: PMC3749917.
    49. Hsu JC, Li Y, Marcus GM, Hsue P, Scherzer R, Grunfeld C, Shlipak MG. Atrial fibrillation and atrial flutter in human immunodeficiency virus-infected persons: incidence, risk factors, and association with markers of HIV disease severity. J Am Coll Cardiol. 2013 Jun 04; 61(22):2288-95. PMID: 23563125.
      View in: PubMed
    50. Waldo SW, Armstrong EJ, Kulkarni A, Hoffmayer K, Kinlay S, Hsue P, Ganz P, McCabe JM. Comparison of clinical characteristics and outcomes of cardiac arrest survivors having versus not having coronary angiography. Am J Cardiol. 2013 May 01; 111(9):1253-8. PMID: 23391104.
      View in: PubMed
    51. Tseng ZH, Moyers B, Secemsky EA, Havlir DV, Hsue P. PR Interval and sudden cardiac death in patients with HIV infection. J Infect Dis. 2013 Jan 01; 207(1):199-200. PMID: 23186784; PMCID: PMC3523799.
    52. Hatano H, Scherzer R, Wu Y, Harvill K, Maka K, Hoh R, Sinclair E, Palmer S, Martin JN, Busch MP, Deeks SG, Hsue P. A randomized controlled trial assessing the effects of raltegravir intensification on endothelial function in treated HIV infection. J Acquir Immune Defic Syndr. 2012 Nov 01; 61(3):317-25. PMID: 22918156; PMCID: PMC3480968.
    53. Selby VN, Scherzer R, Barnett CF, MacGregor JS, Morelli J, Donovan C, Deeks SG, Martin JN, Hsue P. Doppler echocardiography does not accurately estimate pulmonary artery systolic pressure in HIV-infected patients. AIDS. 2012 Sep 24; 26(15):1967-9. PMID: 22781217; PMCID: PMC3897275.
    54. McCabe JM, Armstrong EJ, Hoffmayer KS, Bhave PD, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P. Impact of door-to-activation time on door-to-balloon time in primary percutaneous coronary intervention for ST-segment elevation myocardial infarctions: a report from the Activate-SF registry. Circ Cardiovasc Qual Outcomes. 2012 Sep 01; 5(5):672-9. PMID: 22949494.
      View in: PubMed
    55. Stein JH, Hsue P. Inflammation, immune activation, and CVD risk in individuals with HIV infection. JAMA. 2012 Jul 25; 308(4):405-6. PMID: 22820794.
      View in: PubMed
    56. McCabe JM, Armstrong EJ, Kulkarni A, Hoffmayer KS, Bhave PD, Garg S, Patel A, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P. Prevalence and factors associated with false-positive ST-segment elevation myocardial infarction diagnoses at primary percutaneous coronary intervention–capable centers: a report from the Activate-SF registry. Arch Intern Med. 2012 Jun 11; 172(11):864-71. PMID: 22566489.
      View in: PubMed
    57. Ho JE, Scherzer R, Hecht FM, Maka K, Selby V, Martin JN, Ganz P, Deeks SG, Hsue P. The association of CD4+ T-cell counts and cardiovascular risk in treated HIV disease. AIDS. 2012 Jun 01; 26(9):1115-20. PMID: 22382147; PMCID: PMC3881548.
    58. Hsue P, Deeks SG, Hunt PW. Immunologic basis of cardiovascular disease in HIV-infected adults. J Infect Dis. 2012 Jun; 205 Suppl 3:S375-82. PMID: 22577211; PMCID: PMC3349295.
    59. Frey PF, Ganz P, Hsue P, Benowitz NL, Glantz SA, Balmes JR, Schick SF. The exposure-dependent effects of aged secondhand smoke on endothelial function. J Am Coll Cardiol. 2012 May 22; 59(21):1908-13. PMID: 22595411.
      View in: PubMed
    60. Tseng ZH, Secemsky EA, Dowdy D, Vittinghoff E, Moyers B, Wong JK, Havlir DV, Hsue P. Sudden cardiac death in patients with human immunodeficiency virus infection. J Am Coll Cardiol. 2012 May 22; 59(21):1891-6. PMID: 22595409; PMCID: PMC3356565.
    61. Hsue P, Scherzer R, Hunt PW, Schnell A, Bolger AF, Kalapus SC, Maka K, Martin JN, Ganz P, Deeks SG. Carotid Intima-Media Thickness Progression in HIV-Infected Adults Occurs Preferentially at the Carotid Bifurcation and Is Predicted by Inflammation. J Am Heart Assoc. 2012 Apr; 1(2). PMID: 23130122; PMCID: PMC3487373.
    62. Sacre K, Hunt PW, Hsue P, Maidji E, Martin JN, Deeks SG, Autran B, McCune JM. A role for cytomegalovirus-specific CD4+CX3CR1+ T cells and cytomegalovirus-induced T-cell immunopathology in HIV-associated atherosclerosis. AIDS. 2012 Apr 24; 26(7):805-14. PMID: 22313962; PMCID: PMC4155398.
    63. Armstrong EJ, Kulkarni AR, Hoffmayer KS, Bhave PD, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P, McCabe JM. Delaying primary percutaneous coronary intervention for computed tomographic scans in the emergency department. Am J Cardiol. 2012 Aug 01; 110(3):345-9. PMID: 22534052.
      View in: PubMed
    64. Hsue P, Scherzer R, Grunfeld C, Nordstrom SM, Schnell A, Kohl LP, Nitta E, Martin JN, Deeks SG, Weiss EJ. HIV infection is associated with decreased thrombin generation. Clin Infect Dis. 2012 Apr; 54(8):1196-203. PMID: 22438347; PMCID: PMC3309887.
    65. Almodovar S, Knight R, Allshouse AA, Roemer S, Lozupone C, McDonald D, Widmann J, Voelkel NF, Shelton RJ, Suarez EB, Hammer KW, Goujard C, Petrosillo N, Simonneau G, Hsue P, Humbert M, Flores SC. Human Immunodeficiency Virus nef signature sequences are associated with pulmonary hypertension. AIDS Res Hum Retroviruses. 2012 Jun; 28(6):607-18. PMID: 22066947; PMCID: PMC3358101.
    66. Papasavvas E, Hsue P, Reynolds G, Pistilli M, Hancock A, Martin JN, Deeks SG, Montaner LJ. Increased CD34+/KDR+ cells are not associated with carotid artery intima-media thickness progression in chronic HIV-positive subjects. Antivir Ther. 2012; 17(3):557-63. PMID: 22300770; PMCID: PMC3362125.
    67. Hsue P, Ordovas K, Lee T, Reddy G, Gotway M, Schnell A, Ho JE, Selby V, Madden E, Martin JN, Deeks SG, Ganz P, Waters DD. Carotid intima-media thickness among human immunodeficiency virus-infected patients without coronary calcium. Am J Cardiol. 2012 Mar 01; 109(5):742-7. PMID: 22169125; PMCID: PMC3640832.
    68. Secemsky EA, Lange D, Ho JE, Brayton K, Ganz PA, Farr G, Macgregor JS, Hsue P. Improvement in revascularization time after creation of a coronary catheterization laboratory at a public hospital. Arch Intern Med. 2012 Jan 23; 172(2):193-4. PMID: 22123753.
      View in: PubMed
    69. Secemsky E, Lange D, Waters DD, Goldschlager NF, Hsue P. Hemodynamic and arrhythmogenic effects of cocaine in hypertensive individuals. J Clin Hypertens (Greenwich). 2011 Oct; 13(10):744-9. PMID: 21974762.
      View in: PubMed
    70. Hsue P, Bolger AF, Martin JN. Pulmonary hypertension in HIV-infected individuals. Clin Infect Dis. 2011 Jul 01; 53(1):96; author reply 96-7. PMID: 21653312; PMCID: PMC3110282.
    71. Almodovar S, Hsue P, Morelli J, Huang L, Flores SC. Pathogenesis of HIV-associated pulmonary hypertension: potential role of HIV-1 Nef. Proc Am Thorac Soc. 2011 Jun; 8(3):308-12. PMID: 21653533; PMCID: PMC3132790.
    72. Choi AI, Lo JC, Mulligan K, Schnell A, Kalapus SC, Li Y, Hunt PW, Martin JN, Deeks SG, Hsue P. Association of vitamin D insufficiency with carotid intima-media thickness in HIV-infected persons. Clin Infect Dis. 2011 Apr 01; 52(7):941-4. PMID: 21273298; PMCID: PMC3106229.
    73. Worm SW, Hsue P. Role of biomarkers in predicting CVD risk in the setting of HIV infection? Curr Opin HIV AIDS. 2010 Nov; 5(6):467-72. PMID: 20978389.
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    74. Ho JE, Deeks SG, Hecht FM, Xie Y, Schnell A, Martin JN, Ganz P, Hsue P. Initiation of antiretroviral therapy at higher nadir CD4+ T-cell counts is associated with reduced arterial stiffness in HIV-infected individuals. AIDS. 2010 Jul 31; 24(12):1897-905. PMID: 20543654; PMCID: PMC2903431.
    75. Rangel C, Shu RG, Lazar LD, Vittinghoff E, Hsue P, Marcus GM. Beta-blockers for chest pain associated with recent cocaine use. Arch Intern Med. 2010 May 24; 170(10):874-9. PMID: 20498415.
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    76. Naeger DM, Martin JN, Sinclair E, Hunt PW, Bangsberg DR, Hecht F, Hsue P, McCune JM, Deeks SG. Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease. PLoS One. 2010 Jan 29; 5(1):e8886. PMID: 20126452; PMCID: PMC2813282.
    77. Hsue P, Hunt PW, Ho JE, Farah HH, Schnell A, Hoh R, Martin JN, Deeks SG, Bolger AF. Impact of HIV infection on diastolic function and left ventricular mass. Circ Heart Fail. 2010 Jan; 3(1):132-9. PMID: 19933410; PMCID: PMC2837081.
    78. Ganz P, Hsue P. Assessment of structural disease in the coronary microvasculature. Circulation. 2009 Oct 20; 120(16):1555-7. PMID: 19805646.
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    79. Hsue P, Hunt PW, Wu Y, Schnell A, Ho JE, Hatano H, Xie Y, Martin JN, Ganz P, Deeks SG. Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients. AIDS. 2009 Sep 24; 23(15):2021-7. PMID: 19542863; PMCID: PMC2785446.
    80. Ho JE, Hsue P. Cardiovascular manifestations of HIV infection. Heart. 2009 Jul; 95(14):1193-202. PMID: 19564432.
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    81. Ganz P, Ho JE, Hsue P. Structural and functional manifestations of human atherosclerosis: do they run in parallel? Eur Heart J. 2009 Jul; 30(13):1556-8. PMID: 19502231.
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    82. Hsue P, Hunt PW, Schnell A, Kalapus SC, Hoh R, Ganz P, Martin JN, Deeks SG. Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis. AIDS. 2009 Jun 01; 23(9):1059-67. PMID: 19390417; PMCID: PMC2691772.
    83. Ku IA, Imboden JB, Hsue P, Ganz P. Rheumatoid arthritis: model of systemic inflammation driving atherosclerosis. Circ J. 2009 Jun; 73(6):977-85. PMID: 19430165.
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    84. Hlatky MA, Greenland P, Arnett DK, Ballantyne CM, Criqui MH, Elkind MS, Go AS, Harrell FE, Hong Y, Howard BV, Howard VJ, Hsue P, Kramer CM, McConnell JP, Normand SL, O'Donnell CJ, Smith SC, Wilson PW. Criteria for evaluation of novel markers of cardiovascular risk: a scientific statement from the American Heart Association. Circulation. 2009 May 05; 119(17):2408-16. PMID: 19364974; PMCID: PMC2956982.
    85. Ganz P, Hsue P. Individualized approach to the management of coronary heart disease: identifying the nonresponders before it is too late. J Am Coll Cardiol. 2009 Jan 27; 53(4):331-3. PMID: 19161881.
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    86. Wohl DA, Waters D, Simpson RJ, Richard S, Schnell A, Napravnik S, Keys J, Eron JJ, Hsue P. Ezetimibe alone reduces low-density lipoprotein cholesterol in HIV-infected patients receiving combination antiretroviral therapy. Clin Infect Dis. 2008 Oct 15; 47(8):1105-8. PMID: 18781882.
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    87. Hsue P, Squires K, Bolger AF, Capili B, Mensah GA, Temesgen Z, Wanke CA, Wohl DA. Screening and assessment of coronary heart disease in HIV-infected patients. Circulation. 2008 Jul 08; 118(2):e41-7. PMID: 18566317.
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    88. Grinspoon SK, Grunfeld C, Kotler DP, Currier JS, Lundgren JD, Dubé MP, Lipshultz SE, Hsue P, Squires K, Schambelan M, Wilson PW, Yarasheski KE, Hadigan CM, Stein JH, Eckel RH. State of the science conference: Initiative to decrease cardiovascular risk and increase quality of care for patients living with HIV/AIDS: executive summary. Circulation. 2008 Jul 08; 118(2):198-210. PMID: 18566320; PMCID: PMC3642216.
    89. Hsue P, Deeks SG, Farah HH, Palav S, Ahmed SY, Schnell A, Ellman AB, Huang L, Dollard SC, Martin JN. Role of HIV and human herpesvirus-8 infection in pulmonary arterial hypertension. AIDS. 2008 Apr 23; 22(7):825-33. PMID: 18427200; PMCID: PMC2711076.
    90. McCord J, Jneid H, Hollander JE, de Lemos JA, Cercek B, Hsue P, Gibler WB, Ohman EM, Drew B, Philippides G, Newby LK. Management of cocaine-associated chest pain and myocardial infarction: a scientific statement from the American Heart Association Acute Cardiac Care Committee of the Council on Clinical Cardiology. Circulation. 2008 Apr 08; 117(14):1897-907. PMID: 18347214.
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    91. Barnett CF, Hsue P, Machado RF. Pulmonary hypertension: an increasingly recognized complication of hereditary hemolytic anemias and HIV infection. JAMA. 2008 Jan 23; 299(3):324-31. PMID: 18212317.
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    92. Hunt PW, Brenchley J, Sinclair E, McCune JM, Roland M, Page-Shafer K, Hsue P, Emu B, Krone M, Lampiris H, Douek D, Martin JN, Deeks SG. Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy. J Infect Dis. 2008 Jan 01; 197(1):126-33. PMID: 18171295; PMCID: PMC3466592.
    93. Hsue P, McManus D, Selby V, Ren X, Pillutla P, Younes N, Goldschlager N, Waters DD. Cardiac arrest in patients who smoke crack cocaine. Am J Cardiol. 2007 Mar 15; 99(6):822-4. PMID: 17350374.
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    94. Hsue P, Hunt PW, Sinclair E, Bredt B, Franklin A, Killian M, Hoh R, Martin JN, McCune JM, Waters DD, Deeks SG. Increased carotid intima-media thickness in HIV patients is associated with increased cytomegalovirus-specific T-cell responses. AIDS. 2006 Nov 28; 20(18):2275-83. PMID: 17117013.
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    95. Hsue P, Waters DD. What a cardiologist needs to know about patients with human immunodeficiency virus infection. Circulation. 2005 Dec 20; 112(25):3947-57. PMID: 16365213.
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    96. Emu B, Sinclair E, Favre D, Moretto WJ, Hsue P, Hoh R, Martin JN, Nixon DF, McCune JM, Deeks SG. Phenotypic, functional, and kinetic parameters associated with apparent T-cell control of human immunodeficiency virus replication in individuals with and without antiretroviral treatment. J Virol. 2005 Nov; 79(22):14169-78. PMID: 16254352; PMCID: PMC1280210.
    97. Lo JC, Kazemi MR, Hsue P, Martin JN, Deeks SG, Schambelan M, Mulligan K. The relationship between nucleoside analogue treatment duration, insulin resistance, and fasting arterialized lactate level in patients with HIV infection. Clin Infect Dis. 2005 Nov 01; 41(9):1335-40. PMID: 16206112.
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    98. Ruo B, Tripputi MT, Hsue P, Saigo M, Ouyang P, Waters DD. Usefulness of serum endothelin levels in predicting death and myocardial infarction but not coronary progression in postmenopausal women with coronary disease (from the Women's Angiographic Vitamin and Estrogen [WAVE] study). Am J Cardiol. 2005 Aug 01; 96(3):335-8. PMID: 16054453.
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    99. Saigo M, Hsue P, Waters DD. Role of thrombotic and fibrinolytic factors in acute coronary syndromes. Prog Cardiovasc Dis. 2004 May-Jun; 46(6):524-38. PMID: 15224258.
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    100. Hsue P, Lo JC, Franklin A, Bolger AF, Martin JN, Deeks SG, Waters DD. Progression of atherosclerosis as assessed by carotid intima-media thickness in patients with HIV infection. Circulation. 2004 Apr 06; 109(13):1603-8. PMID: 15023877.
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    101. Hsue P, Giri K, Erickson S, MacGregor JS, Younes N, Shergill A, Waters DD. Clinical features of acute coronary syndromes in patients with human immunodeficiency virus infection. Circulation. 2004 Jan 27; 109(3):316-9. PMID: 14718406.
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    102. Hsue P, Salinas CL, Bolger AF, Benowitz NL, Waters DD. Acute aortic dissection related to crack cocaine. Circulation. 2002 Apr 02; 105(13):1592-5. PMID: 11927528.
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    103. Waters DD, Hsue P. Low-density-lipoprotein cholesterol goals for patients with coronary disease: treating between the lines. Circulation. 2001 Nov 27; 104(22):2635-7. PMID: 11723009.
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    104. Waters DD, Hsue P. What is the role of intensive cholesterol lowering in the treatment of acute coronary syndromes? Am J Cardiol. 2001 Oct 11; 88(7B):7J-16J. PMID: 11595193.
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    105. Sun ZY, Truong HT, Pratt EA, Sutherland DC, Kulig CE, Homer RJ, Groetsch SM, Hsue P, Ho C. A 19F-NMR study of the membrane-binding region of D-lactate dehydrogenase of Escherichia coli. Protein Sci. 1993 Nov; 2(11):1938-47. PMID: 8268803; PMCID: PMC2142291.
    106. Truong HT, Pratt EA, Rule GS, Hsue P, Ho C. Inactive and temperature-sensitive folding mutants generated by tryptophan substitutions in the membrane-bound d-lactate dehydrogenase of Escherichia coli. Biochemistry. 1991 Nov 05; 30(44):10722-9. PMID: 1931992.
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