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Rachael Callcut, MD

Title(s)Associate Professor, Surgery
SchoolSchool of Medicine
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    Collapse Research 
    Collapse Research Activities and Funding
    Leveraging Artificial Intelligence Solutions to Develop Digital Biomarkers for Precision Trauma Resuscitation
    NIH/NHLBI R01HL149670Dec 1, 2019 - Nov 30, 2024
    Role: Principal Investigator
    Advancing Outcome Metrics in Trauma Surgery Through Utilization of Big Data
    NIH/NIEHS K01ES026834Sep 30, 2015 - Jul 31, 2019
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Sammann A, Chehab LZ, Patel D, Liao J, Callcut R, Knudson MM. Improving Efficiency and Meeting Expectations Without Compromising Care on Trauma Surgical Rounds. J Surg Res. 2019 Nov 24. PMID: 31776023.
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    2. Neal MD, Moore EE, Walsh M, Thomas S, Callcut RA, Kornblith LZ, Schreiber M, Ekeh AP, Singer AJ, Lottenberg L, Foreman M, Evans S, Winfield RD, Goodman MD, Freeman C, Milia D, Saillant N, Hartmann J, Achneck HE. A Comparison Between the TEG® 6s and TEG® 5000 Analyzers to Assess Coagulation in Trauma Patients. J Trauma Acute Care Surg. 2019 Nov 11. PMID: 31738314.
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    3. Campion EM, Robinson CK, Brant N, Ferrigno L, McIntyre R, Biesterveld B, Alam H, Callcut R, Mishra S, Platt B, Moore MM, Nahmias J, Grigorian A, Dance S, Britton L, Schroeppel T, Rodriquez J, Shatz D, Becker J, Spalding MC, Wolff TW, Privette AR, Eriksson E, Sahi SL, Patel A, Moore SM, Stiles AL, Moore EE, Cohen MJ, Sauaia A, Burlew CC, Urban S, Osi Udekwu P, Nguyen M, Dibbert A, Conroy A, Ross E, Nunez Garcia B, Albertson S, Dunn J, Alnachaoukati O, Stillman Z, Decker C, Heise H, Burton JS. End-tidal carbon dioxide underestimates plasma carbon dioxide during emergent trauma laparotomy leading to hypoventilation and misguided resuscitation: A Western Trauma Association Multicenter Study. J Trauma Acute Care Surg. 2019 Nov; 87(5):1119-1124. PMID: 31389913.
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    4. Kornblith LZ, Decker A, Conroy AS, Hendrickson CM, Fields AT, Robles AJ, Callcut RA, Cohen MJ. It's About Time: Transfusion effects on postinjury platelet aggregation over time. J Trauma Acute Care Surg. 2019 Nov; 87(5):1042-1051. PMID: 31389915.
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    5. Joseph B, Hanna K, Callcut RA, Coleman JJ, Sakran JV, Neumayer LA. The Hidden Burden of Mental Health Outcomes Following Firearm-related Injures. Ann Surg. 2019 Oct; 270(4):593-601. PMID: 31318795.
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    6. Callcut RA, Robles AM, Kornblith LZ, Plevin RE, Mell MW. Effect of mass shootings on gun sales-A 20-year perspective. J Trauma Acute Care Surg. 2019 Sep; 87(3):531-540. PMID: 31162332.
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    7. Kornblith LZ, Robles AJ, Conroy AS, Redick BJ, Howard BM, Hendrickson CM, Moore S, Nelson MF, Moazed F, Callcut RA, Calfee CS, Cohen MJ. Predictors of postinjury acute respiratory distress syndrome: Lung injury persists in the era of hemostatic resuscitation. J Trauma Acute Care Surg. 2019 Aug; 87(2):371-378. PMID: 31033882.
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    8. Dennis BM, Stonko DP, Callcut RA, Sidwell RA, Stassen NA, Cohen MJ, Cotton BA, Guillamondegui OD. Artificial neural networks can predict trauma volume and acuity regardless of center size and geography: A multicenter study. J Trauma Acute Care Surg. 2019 Jul; 87(1):181-187. PMID: 31033899.
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    9. Miyazawa B, Trivedi A, Togarrati PP, Potter D, Baimukanova G, Vivona L, Lin M, Lopez E, Callcut R, Srivastava AK, Kornblith LZ, Fields AT, Schreiber MA, Wade CE, Holcomb JB, Pati S. Regulation of endothelial cell permeability by platelet-derived extracellular vesicles. J Trauma Acute Care Surg. 2019 Jun; 86(6):931-942. PMID: 31124890.
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    10. Callcut RA, Kornblith LZ, Conroy AS, Robles AJ, Meizoso JP, Namias N, Meyer DE, Haymaker A, Truitt MS, Agrawal V, Haan JM, Lightwine KL, Porter JM, San Roman JL, Biffl WL, Hayashi MS, Sise MJ, Badiee J, Recinos G, Inaba K, Schroeppel TJ, Callaghan E, Dunn JA, Godin S, McIntyre RC, Peltz ED, O'Neill PJ, Diven CF, Scifres AM, Switzer EE, West MA, Storrs S, Cullinane DC, Cordova JF, Moore EE, Moore HB, Privette AR, Eriksson EA, Cohen MJ. The why and how our trauma patients die: A prospective Multicenter Western Trauma Association study. J Trauma Acute Care Surg. 2019 May; 86(5):864-870. PMID: 30633095.
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    11. Christie SA, Conroy AS, Callcut RA, Hubbard AE, Cohen MJ. Dynamic multi-outcome prediction after injury: Applying adaptive machine learning for precision medicine in trauma. PLoS One. 2019; 14(4):e0213836. PMID: 30970030.
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    12. Miyazawa B, Trivedi A, Togarrati PP, Potter D, Baimukanova G, Vivona L, Lin M, Lopez E, Callcut R, Srivastava AK, Kornblith LZ, Fields AT, Schreiber MA, Wade CE, Holcomb JB, Pati S. Regulation of Endothelial Cell Permeability by Platelet-Derived Extracellular Vesicles. J Trauma Acute Care Surg. 2019 Feb 13. PMID: 30768560.
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    13. Robles AJ, Conroy AS, Cohen MJ, Callcut RA. Is it time to measure complications from the National Trauma Data Bank? A longitudinal analysis of recent reporting trends. J Trauma Acute Care Surg. 2019 Feb; 86(2):282-288. PMID: 30489507.
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    14. Sumislawski JJ, Christie SA, Kornblith LZ, Stettler GR, Nunns GR, Moore HB, Moore EE, Silliman CC, Sauaia A, Callcut RA, Cohen MJ. Discrepancies between conventional and viscoelastic assays in identifying trauma-induced coagulopathy. Am J Surg. 2019 Jun; 217(6):1037-1041. PMID: 31029284.
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    15. Stonko DP, Dennis BM, Callcut RA, Betzold RD, Smith MC, Medvecz AJ, Guillamondegui OD. Identifying temporal patterns in trauma admissions: Informing resource allocation. PLoS One. 2018; 13(12):e0207766. PMID: 30507930.
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    16. Christie SA, Hubbard AE, Callcut RA, Hameed M, Dissak-Delon FN, Mekolo D, Saidou A, Mefire AC, Nsongoo P, Dicker RA, Cohen MJ, Juillard C. Machine learning without borders? An adaptable tool to optimize mortality prediction in diverse clinical settings. J Trauma Acute Care Surg. 2018 11; 85(5):921-927. PMID: 30059457.
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    17. Sumislawski JJ, Kornblith LZ, Conroy AS, Callcut RA, Cohen MJ. Dynamic coagulability after injury: Is delaying venous thromboembolism chemoprophylaxis worth the wait? J Trauma Acute Care Surg. 2018 11; 85(5):907-914. PMID: 30124623.
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    18. Burlew CC, Sumislawski JJ, Behnfield CD, McNutt MK, McCarthy J, Sharpe JP, Croce MA, Bala M, Kashuk J, Spalding MC, Beery PR, John S, Hunt DJ, Harmon L, Stein DM, Callcut R, Wybourn C, Sperry J, Anto V, Dunn J, Veith JP, Brown CVR, Celii A, Zander TL, Coimbra R, Berndtson AE, Moss TZ, Malhotra AK, Hazelton JP, Linden K, West M, Alam HB, Williams AM, Kim J, Inaba K, Moulton S, Choi YM, Warren HL, Collier B, Ball CG, Savage S, Hartwell JL, Cullinane DC, Zielinski MD, Ray-Zack MD, Morse BC, Rhee P, Rutherford EJ, Udekwu P, Reynolds C, Toschlog E, Gondek S, Ju T, Haan JM, Lightwine KL, Kulvatunyou N, Coates B, Khouqeer AF, Todd SR, Zarzaur B, Waller CJ, Kallies KJ, Neideen T, Eddine SBZ, Peck KA, Dunne CE, Kramer K, Bokhari F, Dhillon TS, Galante JM, Cohen MJ. Time to stroke: A Western Trauma Association multicenter study of blunt cerebrovascular injuries. J Trauma Acute Care Surg. 2018 11; 85(5):858-866. PMID: 29847537.
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    19. Kornblith LZ, Robles AJ, Conroy AS, Hendrickson CM, Calfee CS, Fields AT, Callcut RA, Cohen MJ. Perhaps it's not the platelet: Ristocetin uncovers the potential role of von Willebrand factor in impaired platelet aggregation following traumatic brain injury. J Trauma Acute Care Surg. 2018 11; 85(5):873-880. PMID: 29985231.
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    20. Callcut RA, Robles AMJ, Mell MW. Banning open carry of unloaded handguns decreases firearm-related fatalities and hospital utilization. Trauma Surg Acute Care Open. 2018; 3(1):e000196. PMID: 30402558.
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    21. Stettler GR, Sumislawski JJ, Moore EE, Nunns GR, Kornblith LZ, Conroy AS, Callcut RA, Silliman CC, Banerjee A, Cohen MJ, Sauaia A. Citrated kaolin thrombelastography (TEG) thresholds for goal-directed therapy in injured patients receiving massive transfusion. J Trauma Acute Care Surg. 2018 10; 85(4):734-740. PMID: 30059456.
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    22. Robinson BRH, Cohen MJ, Holcomb JB, Pritts TA, Gomaa D, Fox EE, Branson RD, Callcut RA, Cotton BA, Schreiber MA, Brasel KJ, Pittet JF, Inaba K, Kerby JD, Scalea TM, Wade CE, Bulger EM. Risk Factors for the Development of Acute Respiratory Distress Syndrome Following Hemorrhage. Shock. 2018 09; 50(3):258-264. PMID: 29194339.
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    23. Robles AJ, Kornblith LZ, Hendrickson CM, Howard BM, Conroy AS, Moazed F, Calfee CS, Cohen MJ, Callcut RA. Health care utilization and the cost of posttraumatic acute respiratory distress syndrome care. J Trauma Acute Care Surg. 2018 07; 85(1):148-154. PMID: 29958249.
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    24. Ferrada P, Callcut RA, Skarupa DJ, Duane TM, Garcia A, Inaba K, Khor D, Anto V, Sperry J, Turay D, Nygaard RM, Schreiber MA, Enniss T, McNutt M, Phelan H, Smith K, Moore FO, Tabas I, Dubose J. Circulation first - the time has come to question the sequencing of care in the ABCs of trauma; an American Association for the Surgery of Trauma multicenter trial. World J Emerg Surg. 2018; 13:8. PMID: 29441123.
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    25. Kunitake RC, Kornblith LZ, Cohen MJ, Callcut RA. Trauma Early Mortality Prediction Tool (TEMPT) for assessing 28-day mortality. Trauma Surg Acute Care Open. 2018; 3(1):e000131. PMID: 29766125.
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    26. Howard BM, Kornblith LZ, Redick BJ, Conroy AS, Nelson MF, Calfee CS, Callcut RA, Cohen MJ. Exposing the bidirectional effects of alcohol on coagulation in trauma: Impaired clot formation and decreased fibrinolysis in rotational thromboelastometry. J Trauma Acute Care Surg. 2018 01; 84(1):97-103. PMID: 29267182.
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    27. Howard BM, Kornblith LZ, Christie SA, Conroy AS, Nelson MF, Campion EM, Callcut RA, Calfee CS, Lamere BJ, Fadrosh DW, Lynch S, Cohen MJ. Characterizing the gut microbiome in trauma: significant changes in microbial diversity occur early after severe injury. Trauma Surg Acute Care Open. 2017; 2(1):e000108. PMID: 29766103.
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    28. Callcut RA, Moore S, Wakam G, Hubbard AE, Cohen MJ. Finding the signal in the noise: Could social media be utilized for early hospital notification of multiple casualty events? PLoS One. 2017; 12(10):e0186118. PMID: 28982201.
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    29. Plevin R, Callcut R. Update in sepsis guidelines: what is really new? Trauma Surg Acute Care Open. 2017; 2(1):e000088. PMID: 29766091.
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    30. Ferrada P, Callcut R, Zielinski MD, Bruns B, Yeh DD, Zakrison TL, Meizoso JP, Sarani B, Catalano RD, Kim P, Plant V, Pasley A, Dultz LA, Choudhry AJ, Haut ER. Loop ileostomy versus total colectomy as surgical treatment for Clostridium difficile-associated disease: An Eastern Association for the Surgery of Trauma multicenter trial. J Trauma Acute Care Surg. 2017 07; 83(1):36-40. PMID: 28426557.
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    31. Christie SA, Kornblith LZ, Howard BM, Conroy AS, Kunitake RC, Nelson MF, Hendrickson CM, Calfee CS, Callcut RA, Cohen MJ. Characterization of distinct coagulopathic phenotypes in injury: Pathway-specific drivers and implications for individualized treatment. J Trauma Acute Care Surg. 2017 06; 82(6):1055-1062. PMID: 28338598.
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    32. Ferrada P, Callcut R, Bauza G, O'Bosky KR, Luo-Owen X, Mansfield NJ, Inaba K, Pasley J, Bugaev N, Pereira B, Moore FO, Han J, Pasley A, DuBose J. Pneumatosis Intestinalis Predictive Evaluation Study: A multicenter epidemiologic study of the American Association for the Surgery of Trauma. J Trauma Acute Care Surg. 2017 03; 82(3):451-460. PMID: 28225738.
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    33. Kunitake RC, Howard BM, Kornblith LZ, Christie SA, Conroy AS, Cohen MJ, Callcut RA. Individual clotting factor contributions to mortality following trauma. J Trauma Acute Care Surg. 2017 02; 82(2):302-308. PMID: 27906868.
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    34. Campion EM, Juillard C, Knudson MM, Dicker R, Cohen MJ, Mackersie R, Campbell AR, Callcut RA. Reconsidering the Resources Needed for Multiple Casualty Events: Lessons Learned From the Crash of Asiana Airlines Flight 214. JAMA Surg. 2016 06 01; 151(6):512-7. PMID: 26764565.
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    35. Callcut RA, Cripps MW, Nelson MF, Conroy AS, Robinson BB, Cohen MJ. The Massive Transfusion Score as a decision aid for resuscitation: Learning when to turn the massive transfusion protocol on and off. J Trauma Acute Care Surg. 2016 Mar; 80(3):450-6. PMID: 26517786.
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    36. Callcut RA, Wakam G, Conroy AS, Kornblith LZ, Howard BM, Campion EM, Nelson MF, Mell MW, Cohen MJ. Discovering the truth about life after discharge: Long-term trauma-related mortality. J Trauma Acute Care Surg. 2016 Feb; 80(2):210-7. PMID: 26606176.
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    37. Howard BM, Kornblith LZ, Conroy AS, Burlew CC, Wagenaar AE, Chouliaras K, Hill JR, Carrick MM, Mallory GR, Watkins JR, Truitt MS, Ciesla DJ, Davis JA, Vail CJ, Kemp Bohan PM, Nelson MF, Callcut RA, Cohen MJ. The found down patient: A Western Trauma Association multicenter study. J Trauma Acute Care Surg. 2015 Dec; 79(6):976-82; discussion 982. PMID: 26488323.
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    38. Sanford T, McCulloch CE, Callcut RA, Carroll PR, Breyer BN. Bicycle Trauma Injuries and Hospital Admissions in the United States, 1998-2013. JAMA. 2015 Sep 01; 314(9):947-9. PMID: 26325564.
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    39. Moore SE, Decker A, Hubbard A, Callcut RA, Fox EE, Del Junco DJ, Holcomb JB, Rahbar MH, Wade CE, Schreiber MA, Alarcon LH, Brasel KJ, Bulger EM, Cotton BA, Muskat P, Myers JG, Phelan HA, Cohen MJ. Statistical Machines for Trauma Hospital Outcomes Research: Application to the PRospective, Observational, Multi-Center Major Trauma Transfusion (PROMMTT) Study. PLoS One. 2015; 10(8):e0136438. PMID: 26296088.
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    40. Howard BM, Kornblith LZ, Hendrickson CM, Redick BJ, Conroy AS, Nelson MF, Callcut RA, Calfee CS, Cohen MJ. Differences in degree, differences in kind: characterizing lung injury in trauma. J Trauma Acute Care Surg. 2015 Apr; 78(4):735-41. PMID: 25742257.
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    41. Holcomb JB, Tilley BC, Baraniuk S, Fox EE, Wade CE, Podbielski JM, del Junco DJ, Brasel KJ, Bulger EM, Callcut RA, Cohen MJ, Cotton BA, Fabian TC, Inaba K, Kerby JD, Muskat P, O'Keeffe T, Rizoli S, Robinson BR, Scalea TM, Schreiber MA, Stein DM, Weinberg JA, Callum JL, Hess JR, Matijevic N, Miller CN, Pittet JF, Hoyt DB, Pearson GD, Leroux B, van Belle G. Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial. JAMA. 2015 Feb 03; 313(5):471-82. PMID: 25647203.
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    42. Kornblith LZ, Howard B, Kunitake R, Redick B, Nelson M, Cohen MJ, Callcut R. Obesity and clotting: Body mass index independently contributes to hypercoagulability after injury. J Trauma Acute Care Surg. 2015 Jan; 78(1):30-6; discussion 37-8. PMID: 25539200.
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    43. Kornblith LZ, Howard BM, Cheung CK, Dayter Y, Pandey S, Busch MP, Pati S, Callcut RA, Vilardi RF, Redick BJ, Nelson MF, Cohen MJ. The whole is greater than the sum of its parts: hemostatic profiles of whole blood variants. J Trauma Acute Care Surg. 2014 Dec; 77(6):818-27. PMID: 25051379.
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    44. Howard BM, Kornblith LZ, Redick BJ, Vilardi RF, Balhotra KS, Crane JM, Forde MR, Nelson MF, Callcut RA, Cohen MJ. The effects of alcohol on coagulation in trauma patients: interpreting thrombelastography with caution. J Trauma Acute Care Surg. 2014 Dec; 77(6):865-71; discussion 871-2. PMID: 25099451.
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    45. Privette AR, Evans AE, Moyer JC, Nelson MF, Knudson MM, Mackersie RC, Callcut RA, Cohen MJ. Beyond emergency surgery: redefining acute care surgery. J Surg Res. 2015 Jun 01; 196(1):166-71. PMID: 25799525.
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    46. Kornblith LZ, Kutcher ME, Callcut RA, Redick BJ, Hu CK, Cogbill TH, Baker CC, Shapiro ML, Burlew CC, Kaups KL, DeMoya MA, Haan JM, Koontz CH, Zolin SJ, Gordy SD, Shatz DV, Paul DB, Cohen MJ. Mechanical ventilation weaning and extubation after spinal cord injury: a Western Trauma Association multicenter study. J Trauma Acute Care Surg. 2013 Dec; 75(6):1060-9; discussion 1069-70. PMID: 24256682.
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    47. Robinson BR, Cotton BA, Pritts TA, Branson R, Holcomb JB, Muskat P, Fox EE, Wade CE, del Junco DJ, Bulger EM, Cohen MJ, Schreiber MA, Myers JG, Brasel KJ, Phelan HA, Alarcon LH, Rahbar MH, Callcut RA. Application of the Berlin definition in PROMMTT patients: the impact of resuscitation on the incidence of hypoxemia. J Trauma Acute Care Surg. 2013 Jul; 75(1 Suppl 1):S61-7. PMID: 23778513.
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    48. Callcut RA, Mell MW. Modern advances in vascular trauma. Surg Clin North Am. 2013 Aug; 93(4):941-61, ix. PMID: 23885939.
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    49. Callcut RA, Cotton BA, Muskat P, Fox EE, Wade CE, Holcomb JB, Schreiber MA, Rahbar MH, Cohen MJ, Knudson MM, Brasel KJ, Bulger EM, Del Junco DJ, Myers JG, Alarcon LH, Robinson BR. Defining when to initiate massive transfusion: a validation study of individual massive transfusion triggers in PROMMTT patients. J Trauma Acute Care Surg. 2013 Jan; 74(1):59-65, 67-8; discussion 66-7. PMID: 23271078.
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    50. Pickham DM, Callcut RA, Maggio PM, Mell MW, Spain DA, Bech F, Staudenmayer K. Payer status is associated with the use of prophylactic inferior vena cava filter in high-risk trauma patients. Surgery. 2012 Aug; 152(2):232-7. PMID: 22828145.
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    51. Mell MW, Callcut RA, Bech F, Delgado MK, Staudenmayer K, Spain DA, Hernandez-Boussard T. Predictors of emergency department death for patients presenting with ruptured abdominal aortic aneurysms. J Vasc Surg. 2012 Sep; 56(3):651-5. PMID: 22560234.
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    52. Callcut RA, Hanseman DJ, Solan PD, Kadon KS, Ingalls NK, Fortuna GR, Tsuei BJ, Robinson BR. Early treatment of blunt cerebrovascular injury with concomitant hemorrhagic neurologic injury is safe and effective. J Trauma Acute Care Surg. 2012 Feb; 72(2):338-45; discussion 345-6. PMID: 22327975.
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    53. Callcut RA, Johannigman JA, Kadon KS, Hanseman DJ, Robinson BR. All massive transfusion criteria are not created equal: defining the predictive value of individual transfusion triggers to better determine who benefits from blood. J Trauma. 2011 Apr; 70(4):794-801. PMID: 21610387.
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    54. Utrup TR, Mueller EW, Healy DP, Callcut RA, Peterson JD, Hurford WE. High-dose ciprofloxacin for serious gram-negative infection in an obese, critically ill patient receiving continuous venovenous hemodiafiltration. Ann Pharmacother. 2010 Oct; 44(10):1660-4. PMID: 20736424.
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    55. Mell MW, O'Neil AS, Callcut RA, Acher CW, Hoch JR, Tefera G, Turnipseed WD. Effect of early plasma transfusion on mortality in patients with ruptured abdominal aortic aneurysm. Surgery. 2010 Nov; 148(5):955-62. PMID: 20378142.
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    56. Callcut RA. What is the best position for preventing ventilator-associated pneumonia? Respir Care. 2010 Mar; 55(3):353-4. PMID: 20196888.
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    57. Callcut RA, Branson RD. How to read a review paper. Respir Care. 2009 Oct; 54(10):1379-85. PMID: 19796419.
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    58. Callcut RA, Acher CW, Hoch J, Tefera G, Turnipseed W, Mell MW. Impact of intraoperative arteriography on limb salvage for traumatic popliteal artery injury. J Trauma. 2009 Aug; 67(2):252-7; discussion 257-8. PMID: 19667876.
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    59. Callcut RA, Breslin TM. Lower nodal counts in axillary dissection following neoadjuvant chemotherapy: are there implications? Am J Surg. 2006 Jun; 191(6):830-1. PMID: 16720160.
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    60. Callcut RA, Schurr MJ, Sloan M, Faucher LD. Clinical experience with Alloderm: a one-staged composite dermal/epidermal replacement utilizing processed cadaver dermis and thin autografts. Burns. 2006 Aug; 32(5):583-8. PMID: 16714089.
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    61. Callcut RA, Breslin TM. Shaping the future of surgery: the role of private regulation in determining quality standards. Ann Surg. 2006 Mar; 243(3):304-12. PMID: 16495692.
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    62. Callcut RA, Rikkers L, Lewis B, Chen H. Does academic advancement impact teaching performance of surgical faculty? Surgery. 2004 Aug; 136(2):277-81. PMID: 15300191.
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    63. Callcut RA, Selvaggi SM, Mack E, Ozgul O, Warner T, Chen H. The utility of frozen section evaluation for follicular thyroid lesions. Ann Surg Oncol. 2004 Jan; 11(1):94-8. PMID: 14699040.
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    64. Callcut R, Snow M, Lewis B, Chen H. Do the best students go into general surgery? J Surg Res. 2003 Nov; 115(1):69-73. PMID: 14572775.
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