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Rajvir Dahiya, PhD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentUrology
Address4150 Clement St
San Francisco CA 94121
Phone415-221-4810 ext. 6964
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    Collapse Research 
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    Molecular biomarkers for kidney cancer prognosis using non-coding RNAs
    NIH/NCI R01CA199694Jun 1, 2016 - May 31, 2021
    Role: Principal Investigator
    Genetic factors for race related prostate cancer.
    NIH/NCI U01CA184966Jul 1, 2015 - Jun 30, 2020
    Role: Principal Investigator
    Role of genetic biomarkers in clinical assessment of prostate cancer
    VA IP1BX001604Oct 1, 2012 - Sep 30, 2016
    Role: Principal Investigator
    Regulation of c-Myc/HIF pathway in the management of kidney cancer
    VA I01BX001123Oct 1, 2011 - Sep 30, 2020
    Role: Principal Investigator
    Chemo-dietary prevention, miRNAs, epigenetic and prostate cancer
    NIH/NCI R01CA160079Jul 6, 2011 - Apr 30, 2016
    Role: Principal Investigator
    MicroRNAs in the Progression and Metastisis of Prostate Cancer
    NIH/NCI R01CA138642Apr 8, 2010 - Jan 31, 2015
    Role: Principal Investigator
    Wnt antagonist genes in kidney tumor progression and metastasis
    NIH/NCI R01CA130860Aug 27, 2008 - May 31, 2014
    Role: Principal Investigator
    Diabetes Erectile dysfunction and apoptosis of cavernous tissues
    NIH/NIDDK R01DK075524Sep 15, 2006 - Aug 31, 2011
    Role: Principal Investigator
    Genistein and Prostate Cancer
    NIH/NCI R01CA111470Aug 9, 2006 - Jul 31, 2011
    Role: Principal Investigator
    Cytochrome-P-450 genes in pathobiology of endometrial cancer
    NIH/NCI R01CA108612Jun 10, 2005 - May 31, 2010
    Role: Principal Investigator
    CYP1A1 and CYP1B1 genes in race-related Prostate Cancer
    NIH/NCI R01CA101844Sep 5, 2003 - Jun 30, 2009
    Role: Principal Investigator
    DNA methylation in aging, race and prostate cancer
    NIH/NIA R01AG021418Jul 15, 2002 - Jun 30, 2007
    Role: Principal Investigator
    Urological Research Training Program
    NIH/NIDDK T32DK007790Sep 15, 2000 - Aug 31, 2012
    Role: Principal Investigator
    DIABETES AND ERECTILE FUNCTION
    NIH/NIDDK R01DK055040Sep 30, 1998 - Aug 31, 2003
    Role: Principal Investigator
    AGING AND PROSTATE GROWTH
    NIH/NIA R01AG016870Sep 1, 1998 - Nov 30, 2003
    Role: Principal Investigator
    SMOOTH MUSCLE-EPITHELIAL INTERACTIONS IN PROSTATE CANCER
    NIH/NCI R01CA064872Sep 30, 1994 - Jul 31, 2002
    Role: Co-Principal Investigator
    PARACRINE MECHANISMS IN HUMAN BENIGN PROSTATIC GROWTH.
    NIH/NIDDK R01DK045861Sep 30, 1994 - Aug 31, 1998
    Role: Principal Investigator
    ESTROGEN AND PROSTATIC GROWTH
    NIH/NIDDK R01DK047517Sep 30, 1993 - Jun 30, 2002
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Yamamoto Y, Tsunedomi R, Fujita Y, Otori T, Ohba M, Kawai Y, Hirata H, Matsumoto H, Haginaka J, Suzuki S, Dahiya R, Hamamoto Y, Matsuyama K, Hazama S, Nagano H, Matsuyama H. Pharmacogenetics-based area-under-curve model can predict efficacy and adverse events from axitinib in individual patients with advanced renal cell carcinoma. Oncotarget. 2018 Mar 30; 9(24):17160-17170. PMID: 29682213.
      View in: PubMed
    2. Dasgupta P, Kulkarni P, Majid S, Varahram S, Hashimoto Y, Bhat NS, Shiina M, Deng G, Saini S, Tabatabai ZL, Yamamura S, Tanaka Y, Dahiya R. MicroRNA-203 inhibits long noncoding RNA HOTAIR and regulates tumorigenesis through epithelial-to-mesenchymal transition pathway in renal cell carcinoma. Mol Cancer Ther. 2018 Feb 13. PMID: 29440295.
      View in: PubMed
    3. Bhagirath D, Yang TL, Bucay N, Sekhon K, Majid S, Shahryari V, Dahiya R, Tanaka Y, Saini S. microRNA-1246 Is an Exosomal Biomarker for Aggressive Prostate Cancer. Cancer Res. 2018 Apr 01; 78(7):1833-1844. PMID: 29437039.
      View in: PubMed
    4. Fujii N, Hirata H, Ueno K, Mori J, Oka S, Shimizu K, Kawai Y, Inoue R, Yamamoto Y, Matsumoto H, Shimabukuro T, Udoh K, Hoshii Y, Dahiya R, Matsuyama H. Extracellular miR-224 as a prognostic marker for clear cell renal cell carcinoma. Oncotarget. 2017 Dec 15; 8(66):109877-109888. PMID: 29299115.
      View in: PubMed
    5. Yoshino H, Nohata N, Miyamoto K, Yonemori M, Sakaguchi T, Sugita S, Itesako T, Kofuji S, Nakagawa M, Dahiya R, Enokida H. PHGDH as a Key Enzyme for Serine Biosynthesis in HIF2a-Targeting Therapy for Renal Cell Carcinoma. Cancer Res. 2017 Nov 15; 77(22):6321-6329. PMID: 28951458.
      View in: PubMed
    6. Imai-Sumida M, Chiyomaru T, Majid S, Saini S, Nip H, Dahiya R, Tanaka Y, Yamamura S. Silibinin suppresses bladder cancer through down-regulation of actin cytoskeleton and PI3K/Akt signaling pathways. Oncotarget. 2017 Nov 03; 8(54):92032-92042. PMID: 29190895.
      View in: PubMed
    7. Yamamura S, Imai-Sumida M, Tanaka Y, Dahiya R. Interaction and cross-talk between non-coding RNAs. Cell Mol Life Sci. 2018 Feb; 75(3):467-484. PMID: 28840253.
      View in: PubMed
    8. Bhat NS, Colden M, Dar AA, Saini S, Arora P, Shahryari V, Yamamura S, Tanaka Y, Kato T, Majid S, Dahiya R. MicroRNA-720 Regulates E-cadherin-aE-catenin Complex and Promotes Renal Cell Carcinoma. Mol Cancer Ther. 2017 Dec; 16(12):2840-2848. PMID: 28802251.
      View in: PubMed
    9. Chang I, Mitsui Y, Kim SK, Sun JS, Jeon HS, Kang JY, Kang NJ, Fukuhara S, Gill A, Shahryari V, Tabatabai ZL, Greene KL, Dahiya R, Shin DM, Tanaka Y. Cytochrome P450 1B1 inhibition suppresses tumorigenicity of prostate cancer via caspase-1 activation. Oncotarget. 2017 Jun 13; 8(24):39087-39100. PMID: 28388569.
      View in: PubMed
    10. Bucay N, Bhagirath D, Sekhon K, Yang T, Fukuhara S, Majid S, Shahryari V, Tabatabai Z, Greene KL, Hashimoto Y, Shiina M, Yamamura S, Tanaka Y, Deng G, Dahiya R, Saini S. A novel microRNA regulator of prostate cancer epithelial-mesenchymal transition. Cell Death Differ. 2017 07; 24(7):1263-1274. PMID: 28498363.
      View in: PubMed
    11. Hashimoto Y, Shiina M, Kato T, Yamamura S, Tanaka Y, Majid S, Saini S, Shahryari V, Kulkarni P, Dasgupta P, Mitsui Y, Sumida M, Deng G, Tabatabai L, Kumar D, Dahiya R. The role of miR-24 as a race related genetic factor in prostate cancer. Oncotarget. 2017 Mar 07; 8(10):16581-16593. PMID: 28157714.
      View in: PubMed
    12. Mitsui Y, Shiina H, Kato T, Maekawa S, Hashimoto Y, Shiina M, Imai-Sumida M, Kulkarni P, Dasgupta P, Wong RK, Hiraki M, Arichi N, Fukuhara S, Yamamura S, Majid S, Saini S, Deng G, Dahiya R, Nakajima K, Tanaka Y. Versican Promotes Tumor Progression, Metastasis and Predicts Poor Prognosis in Renal Carcinoma. Mol Cancer Res. 2017 Jul; 15(7):884-895. PMID: 28242813.
      View in: PubMed
    13. Shiina M, Hashimoto Y, Kato T, Yamamura S, Tanaka Y, Majid S, Saini S, Varahram S, Kulkarni P, Dasgupta P, Mitsui Y, Sumida M, Tabatabai L, Deng G, Kumar D, Dahiya R. Differential expression of miR-34b and androgen receptor pathway regulate prostate cancer aggressiveness between African-Americans and Caucasians. Oncotarget. 2017 Jan 31; 8(5):8356-8368. PMID: 28039468.
      View in: PubMed
    14. Colden M, Dar AA, Saini S, Dahiya PV, Shahryari V, Yamamura S, Tanaka Y, Stein G, Dahiya R, Majid S. MicroRNA-466 inhibits tumor growth and bone metastasis in prostate cancer by direct regulation of osteogenic transcription factor RUNX2. Cell Death Dis. 2017 01 26; 8(1):e2572. PMID: 28125091.
      View in: PubMed
    15. Bucay N, Sekhon K, Majid S, Yamamura S, Shahryari V, Tabatabai ZL, Greene K, Tanaka Y, Dahiya R, Deng G, Saini S. Novel tumor suppressor microRNA at frequently deleted chromosomal region 8p21 regulates epidermal growth factor receptor in prostate cancer. Oncotarget. 2016 Oct 25; 7(43):70388-70403. PMID: 27611943.
      View in: PubMed
    16. Nip H, Dar AA, Saini S, Colden M, Varahram S, Chowdhary H, Yamamura S, Mitsui Y, Tanaka Y, Kato T, Hashimoto Y, Shiina M, Kulkarni P, Dasgupta P, Imai-Sumida M, Tabatabai ZL, Greene K, Deng G, Dahiya R, Majid S. Oncogenic microRNA-4534 regulates PTEN pathway in prostate cancer. Oncotarget. 2016 Oct 18; 7(42):68371-68384. PMID: 27634912.
      View in: PubMed
    17. Sekhon K, Bucay N, Majid S, Dahiya R, Saini S. MicroRNAs and epithelial-mesenchymal transition in prostate cancer. Oncotarget. 2016 Oct 11; 7(41):67597-67611. PMID: 27588490.
      View in: PubMed
    18. Shahryari V, Nip H, Saini S, Dar AA, Yamamura S, Mitsui Y, Colden M, Bucay N, Tabatabai LZ, Greene K, Deng G, Tanaka Y, Dahiya R, Majid S. Pre-clinical Orthotopic Murine Model of Human Prostate Cancer. J Vis Exp. 2016 Aug 29; (114). PMID: 27684100.
      View in: PubMed
    19. Mitsui Y, Chang I, Kato T, Hashimoto Y, Yamamura S, Fukuhara S, Wong DK, Shiina M, Imai-Sumida M, Majid S, Saini S, Shiina H, Nakajima K, Deng G, Dahiya R, Tanaka Y. Functional role and tobacco smoking effects on methylation of CYP1A1 gene in prostate cancer. Oncotarget. 2016 Aug 02; 7(31):49107-49121. PMID: 27203547.
      View in: PubMed
    20. Mitsui Y, Chang I, Fukuhara S, Hiraki M, Arichi N, Yasumoto H, Hirata H, Yamamura S, Shahryari V, Deng G, Wong DK, Majid S, Shiina H, Dahiya R, Tanaka Y. CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma. BMC Cancer. 2015 Dec 01; 15:942. PMID: 26626260; PMCID: PMC4665921.
    21. Bucay N, Shahryari V, Majid S, Yamamura S, Mitsui Y, Tabatabai ZL, Greene K, Deng G, Dahiya R, Tanaka Y, Saini S. miRNA Expression Analyses in Prostate Cancer Clinical Tissues. J Vis Exp. 2015 Sep 08; (103). PMID: 26382040; PMCID: PMC4692597.
    22. Fukuhara S, Chang I, Mitsui Y, Chiyomaru T, Yamamura S, Majid S, Saini S, Deng G, Gill A, Wong DK, Shiina H, Nonomura N, Lau YF, Dahiya R, Tanaka Y. Functional role of DNA mismatch repair gene PMS2 in prostate cancer cells. Oncotarget. 2015 Jun 30; 6(18):16341-51. PMID: 26036629; PMCID: PMC4599273.
    23. Mitsui Y, Hirata H, Arichi N, Hiraki M, Yasumoto H, Chang I, Fukuhara S, Yamamura S, Shahryari V, Deng G, Saini S, Majid S, Dahiya R, Tanaka Y, Shiina H. Inactivation of bone morphogenetic protein 2 may predict clinical outcome and poor overall survival for renal cell carcinoma through epigenetic pathways. Oncotarget. 2015 Apr 20; 6(11):9577-91. PMID: 25797254; PMCID: PMC4496240.
    24. Chang I, Mitsui Y, Fukuhara S, Gill A, Wong DK, Yamamura S, Shahryari V, Tabatabai ZL, Dahiya R, Shin DM, Tanaka Y. Loss of miR-200c up-regulates CYP1B1 and confers docetaxel resistance in renal cell carcinoma. Oncotarget. 2015 Apr 10; 6(10):7774-87. PMID: 25860934; PMCID: PMC4480715.
    25. Arichi N, Mitsui Y, Hiraki M, Nakamura S, Hiraoka T, Sumura M, Hirata H, Tanaka Y, Dahiya R, Yasumoto H, Shiina H. Versican is a potential therapeutic target in docetaxel-resistant prostate cancer. Oncoscience. 2015; 2(2):193-204. PMID: 25859560; PMCID: PMC4381710.
    26. Hirata H, Hinoda Y, Shahryari V, Deng G, Nakajima K, Tabatabai ZL, Ishii N, Dahiya R. Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205. Cancer Res. 2015 Apr 01; 75(7):1322-31. PMID: 25600645.
      View in: PubMed
    27. Fukuhara S, Chang I, Mitsui Y, Chiyomaru T, Yamamura S, Majid S, Saini S, Hirata H, Deng G, Gill A, Wong DK, Shiina H, Nonomura N, Dahiya R, Tanaka Y. DNA mismatch repair gene MLH1 induces apoptosis in prostate cancer cells. Oncotarget. 2014 Nov 30; 5(22):11297-307. PMID: 25526032; PMCID: PMC4294331.
    28. Chang I, Fukuhara S, Wong DK, Gill A, Mitsui Y, Majid S, Saini S, Yamamura S, Chiyomaru T, Hirata H, Ueno K, Arora S, Shahryari V, Deng G, Tabatabai ZL, Greene KL, Shin DM, Enokida H, Shiina H, Nonomura N, Dahiya R, Tanaka Y. Cytochrome P450 1B1 polymorphisms and risk of renal cell carcinoma in men. Tumour Biol. 2014 Oct; 35(10):10223-30. PMID: 25027399.
      View in: PubMed
    29. Saini S, Majid S, Shahryari V, Tabatabai ZL, Arora S, Yamamura S, Tanaka Y, Dahiya R, Deng G. Regulation of SRC kinases by microRNA-3607 located in a frequently deleted locus in prostate cancer. Mol Cancer Ther. 2014 Jul; 13(7):1952-63. PMID: 24817628; PMCID: PMC4351861.
    30. Mitsui Y, Yasumoto H, Nagami T, Hiraki M, Arichi N, Ishikawa N, Araki A, Maruyama R, Tanaka Y, Dahiya R, Shiina H. Extracellular activation of Wnt signaling through epigenetic dysregulation of Wnt inhibitory factor-1 (Wif-1) is associated with pathogenesis of adrenocortical tumor. Oncotarget. 2014 Apr 30; 5(8):2198-207. PMID: 24755523; PMCID: PMC4039156.
    31. Chiyomaru T, Fukuhara S, Saini S, Majid S, Deng G, Shahryari V, Chang I, Tanaka Y, Enokida H, Nakagawa M, Dahiya R, Yamamura S. Long non-coding RNA HOTAIR is targeted and regulated by miR-141 in human cancer cells. J Biol Chem. 2014 May 02; 289(18):12550-65. PMID: 24616104; PMCID: PMC4007447.
    32. Arora S, Saini S, Fukuhara S, Majid S, Shahryari V, Yamamura S, Chiyomaru T, Deng G, Tanaka Y, Dahiya R. MicroRNA-4723 inhibits prostate cancer growth through inactivation of the Abelson family of nonreceptor protein tyrosine kinases. PLoS One. 2013; 8(11):e78023. PMID: 24223753; PMCID: PMC3815229.
    33. Chiyomaru T, Yamamura S, Fukuhara S, Yoshino H, Kinoshita T, Majid S, Saini S, Chang I, Tanaka Y, Enokida H, Seki N, Nakagawa M, Dahiya R. Genistein inhibits prostate cancer cell growth by targeting miR-34a and oncogenic HOTAIR. PLoS One. 2013; 8(8):e70372. PMID: 23936419; PMCID: PMC3731248.
    34. Majid S, Dar AA, Saini S, Deng G, Chang I, Greene K, Tanaka Y, Dahiya R, Yamamura S. MicroRNA-23b functions as a tumor suppressor by regulating Zeb1 in bladder cancer. PLoS One. 2013; 8(7):e67686. PMID: 23844063; PMCID: PMC3699593.
    35. Chang I, Majid S, Saini S, Zaman MS, Yamamura S, Chiyomaru T, Shahryari V, Fukuhara S, Deng G, Dahiya R, Tanaka Y. Hrk mediates 2-methoxyestradiol-induced mitochondrial apoptotic signaling in prostate cancer cells. Mol Cancer Ther. 2013 Jun; 12(6):1049-59. PMID: 23580416.
      View in: PubMed
    36. Chiyomaru T, Yamamura S, Fukuhara S, Hidaka H, Majid S, Saini S, Arora S, Deng G, Shahryari V, Chang I, Tanaka Y, Tabatabai ZL, Enokida H, Seki N, Nakagawa M, Dahiya R. Genistein up-regulates tumor suppressor microRNA-574-3p in prostate cancer. PLoS One. 2013; 8(3):e58929. PMID: 23554959.
      View in: PubMed
    37. Hirata H, Ueno K, Shahryari V, Deng G, Tanaka Y, Tabatabai ZL, Hinoda Y, Dahiya R. MicroRNA-182-5p promotes cell invasion and proliferation by down regulating FOXF2, RECK and MTSS1 genes in human prostate cancer. PLoS One. 2013; 8(1):e55502. PMID: 23383207; PMCID: PMC3559583.
    38. Hirata H, Ueno K, Shahryari V, Tanaka Y, Tabatabai ZL, Hinoda Y, Dahiya R. Oncogenic miRNA-182-5p targets Smad4 and RECK in human bladder cancer. PLoS One. 2012; 7(11):e51056. PMID: 23226455; PMCID: PMC3511415.
    39. Zaman MS, Thamminana S, Shahryari V, Chiyomaru T, Deng G, Saini S, Majid S, Fukuhara S, Chang I, Arora S, Hirata H, Ueno K, Singh K, Tanaka Y, Dahiya R. Inhibition of PTEN gene expression by oncogenic miR-23b-3p in renal cancer. PLoS One. 2012; 7(11):e50203. PMID: 23189187; PMCID: PMC3506541.
    40. Majid S, Dar AA, Saini S, Shahryari V, Arora S, Zaman MS, Chang I, Yamamura S, Tanaka Y, Chiyomaru T, Deng G, Dahiya R. miRNA-34b inhibits prostate cancer through demethylation, active chromatin modifications, and AKT pathways. Clin Cancer Res. 2013 Jan 01; 19(1):73-84. PMID: 23147995; PMCID: PMC3910324.
    41. Majid S, Dar AA, Saini S, Arora S, Shahryari V, Zaman MS, Chang I, Yamamura S, Tanaka Y, Deng G, Dahiya R. miR-23b represses proto-oncogene Src kinase and functions as methylation-silenced tumor suppressor with diagnostic and prognostic significance in prostate cancer. Cancer Res. 2012 Dec 15; 72(24):6435-46. PMID: 23074286; PMCID: PMC3940348.
    42. Mitsui Y, Shiina H, Hiraoka T, Arichi N, Yasumoto H, Dahiya R, Tanagho EA, Igawa M. Simultaneous implantation of bilateral ureters into bladder acellular matrix graft after partial cystectomy in a porcine model. BJU Int. 2012 Dec; 110(11 Pt C):E1212-7. PMID: 23046198.
      View in: PubMed
    43. Majid S, Dar AA, Saini S, Shahryari V, Arora S, Zaman MS, Chang I, Yamamura S, Chiyomaru T, Fukuhara S, Tanaka Y, Deng G, Tabatabai ZL, Dahiya R. MicroRNA-1280 inhibits invasion and metastasis by targeting ROCK1 in bladder cancer. PLoS One. 2012; 7(10):e46743. PMID: 23056431; PMCID: PMC3464246.
    44. Ueno K, Hirata H, Hinoda Y, Dahiya R. Frizzled homolog proteins, microRNAs and Wnt signaling in cancer. Int J Cancer. 2013 Apr 15; 132(8):1731-40. PMID: 22833265; PMCID: PMC3940357.
    45. Chiyomaru T, Yamamura S, Zaman MS, Majid S, Deng G, Shahryari V, Saini S, Hirata H, Ueno K, Chang I, Tanaka Y, Tabatabai ZL, Enokida H, Nakagawa M, Dahiya R. Genistein suppresses prostate cancer growth through inhibition of oncogenic microRNA-151. PLoS One. 2012; 7(8):e43812. PMID: 22928040; PMCID: PMC3426544.
    46. Saini S, Majid S, Shahryari V, Arora S, Yamamura S, Chang I, Zaman MS, Deng G, Tanaka Y, Dahiya R. miRNA-708 control of CD44(+) prostate cancer-initiating cells. Cancer Res. 2012 Jul 15; 72(14):3618-30. PMID: 22552290.
      View in: PubMed
    47. Majid S, Saini S, Dahiya R. Wnt signaling pathways in urological cancers: past decades and still growing. Mol Cancer. 2012 Feb 10; 11:7. PMID: 22325146; PMCID: PMC3293036.
    48. Zaman MS, Shahryari V, Deng G, Thamminana S, Saini S, Majid S, Chang I, Hirata H, Ueno K, Yamamura S, Singh K, Tanaka Y, Tabatabai ZL, Dahiya R. Up-regulation of microRNA-21 correlates with lower kidney cancer survival. PLoS One. 2012; 7(2):e31060. PMID: 22347428; PMCID: PMC3275568.
    49. Yamamura S, Saini S, Majid S, Hirata H, Ueno K, Deng G, Dahiya R. MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells. PLoS One. 2012; 7(1):e29722. PMID: 22235332; PMCID: PMC3250472.
    50. Hirata H, Hinoda Y, Ueno K, Nakajima K, Ishii N, Dahiya R. MicroRNA-1826 directly targets beta-catenin (CTNNB1) and MEK1 (MAP2K1) in VHL-inactivated renal cancer. Carcinogenesis. 2012 Mar; 33(3):501-8. PMID: 22180573; PMCID: PMC3291860.
    51. Yamamura S, Saini S, Majid S, Hirata H, Ueno K, Chang I, Tanaka Y, Gupta A, Dahiya R. MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinoma. Carcinogenesis. 2012 Feb; 33(2):294-300. PMID: 22159222; PMCID: PMC3271269.
    52. Chang I, Liu J, Majid S, Saini S, Zaman MS, Yamamura S, Shahryari V, Chiyomaru T, Deng G, Dahiya R, Tanaka Y. Catechol-O-methyltransferase-mediated metabolism of 4-hydroxyestradiol inhibits the growth of human renal cancer cells through the apoptotic pathway. Carcinogenesis. 2012 Feb; 33(2):420-6. PMID: 22159223.
      View in: PubMed
    53. Nishioka M, Ueno K, Hazama S, Okada T, Sakai K, Suehiro Y, Okayama N, Hirata H, Oka M, Imai K, Dahiya R, Hinoda Y. Possible involvement of Wnt11 in colorectal cancer progression. Mol Carcinog. 2013 Mar; 52(3):207-17. PMID: 22161723.
      View in: PubMed
    54. Ueno K, Hirata H, Majid S, Yamamura S, Shahryari V, Tabatabai ZL, Hinoda Y, Dahiya R. Tumor suppressor microRNA-493 decreases cell motility and migration ability in human bladder cancer cells by downregulating RhoC and FZD4. Mol Cancer Ther. 2012 Jan; 11(1):244-53. PMID: 22057916; PMCID: PMC3940358.
    55. Hirata H, Hinoda Y, Ueno K, Shahryari V, Tabatabai ZL, Dahiya R. MicroRNA-1826 targets VEGFC, beta-catenin (CTNNB1) and MEK1 (MAP2K1) in human bladder cancer. Carcinogenesis. 2012 Jan; 33(1):41-8. PMID: 22049531; PMCID: PMC3276333.
    56. Saini S, Majid S, Dahiya R. The complex roles of Wnt antagonists in RCC. Nat Rev Urol. 2011 Oct 25; 8(12):690-9. PMID: 22025172.
      View in: PubMed
    57. Mahimkar R, Alfonso-Jaume MA, Cape LM, Dahiya R, Lovett DH. Graded activation of the MEK1/MT1-MMP axis determines renal epithelial cell tumor phenotype. Carcinogenesis. 2011 Dec; 32(12):1806-14. PMID: 21965271; PMCID: PMC3220610.
    58. Saini S, Yamamura S, Majid S, Shahryari V, Hirata H, Tanaka Y, Dahiya R. MicroRNA-708 induces apoptosis and suppresses tumorigenicity in renal cancer cells. Cancer Res. 2011 Oct 01; 71(19):6208-19. PMID: 21852381; PMCID: PMC3940359.
    59. Saini S, Arora S, Majid S, Shahryari V, Chen Y, Deng G, Yamamura S, Ueno K, Dahiya R. Curcumin modulates microRNA-203-mediated regulation of the Src-Akt axis in bladder cancer. Cancer Prev Res (Phila). 2011 Oct; 4(10):1698-709. PMID: 21836020; PMCID: PMC3940389.
    60. Hirata H, Hinoda Y, Nakajima K, Kawamoto K, Kikuno N, Ueno K, Yamamura S, Zaman MS, Khatri G, Chen Y, Saini S, Majid S, Deng G, Ishii N, Dahiya R. Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma. Int J Cancer. 2011 Apr 15; 128(8):1793-803. PMID: 20549706.
      View in: PubMed
    61. Ueno K, Hirata H, Majid S, Tabatabai ZL, Hinoda Y, Dahiya R. IGFBP-4 activates the Wnt/beta-catenin signaling pathway and induces M-CAM expression in human renal cell carcinoma. Int J Cancer. 2011 Nov 15; 129(10):2360-9. PMID: 21207373.
      View in: PubMed
    62. Suh SO, Chen Y, Zaman MS, Hirata H, Yamamura S, Shahryari V, Liu J, Tabatabai ZL, Kakar S, Deng G, Tanaka Y, Dahiya R. MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer. Carcinogenesis. 2011 May; 32(5):772-8. PMID: 21349819; PMCID: PMC3086703.
    63. Majid S, Saini S, Dar AA, Hirata H, Shahryari V, Tanaka Y, Yamamura S, Ueno K, Zaman MS, Singh K, Chang I, Deng G, Dahiya R. MicroRNA-205 inhibits Src-mediated oncogenic pathways in renal cancer. Cancer Res. 2011 Apr 01; 71(7):2611-21. PMID: 21330408; PMCID: PMC3940352.
    64. Kawakami K, Yamamura S, Hirata H, Ueno K, Saini S, Majid S, Tanaka Y, Kawamoto K, Enokida H, Nakagawa M, Dahiya R. Secreted frizzled-related protein-5 is epigenetically downregulated and functions as a tumor suppressor in kidney cancer. Int J Cancer. 2011 Feb 01; 128(3):541-50. PMID: 20340127; PMCID: PMC3940353.
    65. Ueno K, Hirata H, Majid S, Chen Y, Zaman MS, Tabatabai ZL, Hinoda Y, Dahiya R. Wnt antagonist DICKKOPF-3 (Dkk-3) induces apoptosis in human renal cell carcinoma. Mol Carcinog. 2011 Jun; 50(6):449-57. PMID: 21268126.
      View in: PubMed
    66. Patra A, Deb M, Dahiya R, Patra SK. 5-Aza-2'-deoxycytidine stress response and apoptosis in prostate cancer. Clin Epigenetics. 2011 Aug; 2(2):339-48. PMID: 22704346; PMCID: PMC3365594.
    67. Chen Y, Saini S, Zaman MS, Hirata H, Shahryari V, Deng G, Dahiya R. Cytochrome P450 17 (CYP17) is involved in endometrial cancinogenesis through apoptosis and invasion pathways. Mol Carcinog. 2011 Jan; 50(1):16-23. PMID: 20886547.
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    151. Yamanaka M, Shirai M, Shiina H, Tanaka Y, Tsujimura A, Matsumiya K, Okuyama A, Dahiya R. Diabetes induced erectile dysfunction and apoptosis in penile crura are recovered by insulin treatment in rats. J Urol. 2003 Jul; 170(1):291-7. PMID: 12796708.
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    152. Sasaki M, Kaneuchi M, Sakuragi N, Dahiya R. Multiple promoters of catechol-O-methyltransferase gene are selectively inactivated by CpG hypermethylation in endometrial cancer. Cancer Res. 2003 Jun 15; 63(12):3101-6. PMID: 12810635.
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    153. Sasaki M, Sakuragi N, Dahiya R. The CAG repeats in exon 1 of the androgen receptor gene are significantly longer in endometrial cancer patients. Biochem Biophys Res Commun. 2003 Jun 13; 305(4):1105-8. PMID: 12767946.
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    154. Shiina H, Igawa M, Breault J, Ribeiro-Filho L, Pookot D, Urakami S, Terashima M, Deguchi M, Yamanaka M, Shirai M, Kaneuchi M, Kane CJ, Dahiya R. The human T-cell factor-4 gene splicing isoforms, Wnt signal pathway, and apoptosis in renal cell carcinoma. Clin Cancer Res. 2003 Jun; 9(6):2121-32. PMID: 12796377.
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    155. Deguchi M, Shiina H, Igawa M, Kaneuchi M, Nakajima K, Dahiya R. DNA mismatch repair genes in renal cell carcinoma. J Urol. 2003 Jun; 169(6):2365-71. PMID: 12771799.
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    156. Sasaki M, Tanaka Y, Kaneuchi M, Sakuragi N, Dahiya R. Alleles of polymorphic sites that correspond to hyperactive variants of CYP1B1 protein are significantly less frequent in Japanese as compared to American and German populations. Hum Mutat. 2003 Jun; 21(6):652. PMID: 14961553.
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    157. Tanaka Y, Sasaki M, Kaneuchi M, Fujimoto S, Dahiya R. Estrogen receptor alpha polymorphisms and renal cell carcinoma--a possible risk. Mol Cell Endocrinol. 2003 Apr 28; 202(1-2):109-16. PMID: 12770739.
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    158. Sasaki M, Kaneuchi M, Fujimoto S, Tanaka Y, Dahiya R. Hypermethylation can selectively silence multiple promoters of steroid receptors in cancers. Mol Cell Endocrinol. 2003 Apr 28; 202(1-2):201-7. PMID: 12770752.
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    159. Sasaki M, Kaneuchi M, Fujimoto S, Tanaka Y, Dahiya R. CYP1B1 gene in endometrial cancer. Mol Cell Endocrinol. 2003 Apr 28; 202(1-2):171-6. PMID: 12770747.
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    160. Marker PC, Dahiya R, Cunha GR. Spontaneous mutation in mice provides new insight into the genetic mechanisms that pattern the seminal vesicles and prostate gland. Dev Dyn. 2003 Apr; 226(4):643-53. PMID: 12666202.
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    161. Patra SK, Patra A, Zhao H, Carroll P, Dahiya R. Methyl-CpG-DNA binding proteins in human prostate cancer: expression of CXXC sequence containing MBD1 and repression of MBD2 and MeCP2. Biochem Biophys Res Commun. 2003 Mar 21; 302(4):759-66. PMID: 12646234.
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    162. Marker PC, Donjacour AA, Dahiya R, Cunha GR. Hormonal, cellular, and molecular control of prostatic development. Dev Biol. 2003 Jan 15; 253(2):165-74. PMID: 12645922.
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    163. Li LC, Zhao H, Shiina H, Kane CJ, Dahiya R. PGDB: a curated and integrated database of genes related to the prostate. Nucleic Acids Res. 2003 Jan 01; 31(1):291-3. PMID: 12520005; PMCID: PMC165455.
    164. Kaneuchi M, Sasaki M, Tanaka Y, Sakuragi N, Fujimoto S, Dahiya R. Quercetin regulates growth of Ishikawa cells through the suppression of EGF and cyclin D1. Int J Oncol. 2003 Jan; 22(1):159-64. PMID: 12469199.
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    165. Li LC, Dahiya R. MethPrimer: designing primers for methylation PCRs. Bioinformatics. 2002 Nov; 18(11):1427-31. PMID: 12424112.
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    166. Yamanaka M, Shirai M, Shiina H, Shirai M, Tanaka Y, Fujime M, Okuyama A, Dahiya R. Loss of anti-apoptotic genes in aging rat crura. J Urol. 2002 Nov; 168(5):2296-300. PMID: 12394778.
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    167. Shiina H, Igawa M, Shigeno K, Terashima M, Deguchi M, Yamanaka M, Ribeiro-Filho L, Kane CJ, Dahiya R. Beta-catenin mutations correlate with over expression of C-myc and cyclin D1 Genes in bladder cancer. J Urol. 2002 Nov; 168(5):2220-6. PMID: 12394763.
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    168. Sasaki M, Tanaka Y, Kaneuchi M, Sakuragi N, Dahiya R. Polymorphisms of estrogen receptor alpha gene in endometrial cancer. Biochem Biophys Res Commun. 2002 Sep 27; 297(3):558-64. PMID: 12270131.
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    169. Tanaka Y, Sasaki M, Kaneuchi M, Fujimoto S, Dahiya R. Single nucleotide polymorphisms of estrogen receptor alpha in human renal cell carcinoma. Biochem Biophys Res Commun. 2002 Sep 06; 296(5):1200-6. PMID: 12207901.
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    170. Tanaka Y, Sasaki M, Kaneuchi M, Shiina H, Igawa M, Dahiya R. Polymorphisms of the CYP1B1 gene have higher risk for prostate cancer. Biochem Biophys Res Commun. 2002 Aug 30; 296(4):820-6. PMID: 12200121.
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    171. Ribeiro-Filho LA, Franks J, Sasaki M, Shiina H, Li LC, Nojima D, Arap S, Carroll P, Enokida H, Nakagawa M, Yonezawa S, Dahiya R. CpG hypermethylation of promoter region and inactivation of E-cadherin gene in human bladder cancer. Mol Carcinog. 2002 Aug; 34(4):187-98. PMID: 12203370.
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    172. Cayan S, Chermansky C, Schlote N, Sekido N, Nunes L, Dahiya R, Tanagho EA. The bladder acellular matrix graft in a rat chemical cystitis model: functional and histologic evaluation. J Urol. 2002 Aug; 168(2):798-804. PMID: 12131370.
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    173. Zhao H, Patra A, Tanaka Y, Li LC, Dahiya R. Transforming growth factor-beta(s) and their receptors in aging rat prostate. Biochem Biophys Res Commun. 2002 Jun 07; 294(2):464-9. PMID: 12051734.
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    174. Wefer J, Sekido N, Sievert KD, Schlote N, Nunes L, Dahiya R, Jonas U, Tanagho EA. Homologous acellular matrix graft for vaginal repair in rats: a pilot study for a new reconstructive approach. World J Urol. 2002 Sep; 20(4):260-3. PMID: 12215858.
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    175. Zhao H, Patra A, Yeh CC, Tanaka Y, Oh BR, Dahiya R. Effects of aging on growth factors gene and protein expression in the dorsal and ventral lobes of rat prostate. Biochem Biophys Res Commun. 2002 Mar 29; 292(2):482-91. PMID: 11906188.
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    176. Sasaki M, Tanaka Y, Perinchery G, Dharia A, Kotcherguina I, Fujimoto Si, Dahiya R. Methylation and inactivation of estrogen, progesterone, and androgen receptors in prostate cancer. J Natl Cancer Inst. 2002 Mar 06; 94(5):384-90. PMID: 11880477.
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    177. Patra SK, Patra A, Zhao H, Dahiya R. DNA methyltransferase and demethylase in human prostate cancer. Mol Carcinog. 2002 Mar; 33(3):163-71. PMID: 11870882.
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    178. Dasari VK, Deng D, Perinchery G, Yeh CC, Dahiya R. DNA methylation regulates the expression of Y chromosome specific genes in prostate cancer. J Urol. 2002 Jan; 167(1):335-8. PMID: 11743352.
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