Rena Fox, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address1545 Divisadero Street, #307
San Francisco CA 94115
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    Collapse Biography 
    Collapse Education and Training
    Stanford UniversityB.A.1991Human Biology
    Bryn Mawr CollegePost-Baccalaureate1992
    University of California San DiegoM.D.1997School of Medicine
    University of WashingtonInternship and Residency2000Internal Medicine
    UCSFClinician-Educator Fellowship2001General Internal Medicine
    University of California, San Francisco, CA2018Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    UCSF2019UCSF Health Team PRIDE Award Winner for UCSF HCV Project ECHO
    UCSF Academy of Medical Educators2013Excellence in Teaching Award, The Haile T. Debas Academy of Medical Educators
    UCSF Division of General Internal Medicine2010Robert H. Crede Award for Clinical Care
    EASL (European Association for the Study of the Liver)2008Top 10% Research Poster
    AASLD2003The Jan Albrecht Commitment to Clinical Research in Liver Diseases Award
    University of Washington2000Outstanding Resident of the Year, Department of Medicine

    Collapse Overview 
    Collapse Overview
    Dr. Rena Fox is a Professor of Clinical Medicine in the Department of Medicine, Division of General Internal Medicine since 2001. Dr. Fox was an undergraduate at Stanford, got her MD at UC San Diego and did her internal medicine residency at University of Washington. She was a general medicine clinician-educator fellow at UCSF with an interest in hepatitis C virus (HCV) during which time she was trained by UCSF hepatologists. Since then, her research has focused on improving the care of patients with liver disease. She studied the prevalence of HCV in the California prisons and was awarded the Jan Albrecht Award from AASLD. Her work includes studying electronic medical record strategies for improved HCV screening in primary care, cost-efficacy of DAA treatments, outcomes of cirrhosis and hepatocellular carcinoma (HCC), and algorithms for primary care providers to detect and risk stratify patients with NAFLD and advanced fibrosis. She worked with the VA for over a decade on creating HCV educational tools, national policies, and curriculum as medical editor for the VA Viral Hepatitis Website. As part of the CDC and DHHS Hepatitis Action Plan, she served as an editor for Hepatitis C Online, a curriculum for HCV education. She was a co-author and panel member of the clinical practice guidelines for the VA regarding the use of DAAs from 2013-2021. Dr. Fox is currently a voting panel member and the Chair of California Technology Assessment Forum (CTAF), a partner of the Institute for Clinical and Economic Review (ICER). CTAF is an independent panel of medical experts who works with ICER to evaluate the clinical and economic value of new drugs, across all fields. She also proves telemedicine consultation on HCV management for providers in underserved and rural areas for the UCSF Hepatitis C ECHO clinic. Dr. Fox is currently a member of the AASLD Foundations in Liver Disease Committee. She is Co-Chair of the SFCAN Liver Cancer Task Force, through the Cancer Center, bringing together multiple entities working to reduce the incidence and mortality of HCC and she is on the Executive Advisory Board for End Hep C SF. Examples of her university service include the UCSF and System-wide Committee on Committees (Chair, UCSF), the SOM Faculty Council, the DOM Promotions Subcommittee and the UC Primary Care Residency Selection committee. She was also asked to chair two UCSF Task Forces regarding the affiliations between UCSF and faith-based hospitals. Since then she has served as the Senate representative on the UCSF Health Leadership Council. She will serve a 3 year term as the UCSF representative for the UCOP Joint Clinical Advisory Committee on Covered Affiliations (2022-2025). In clinical practice, she maintains a busy and large primary care panel in General Medicine Practice at the Mt. Zion campus and for 19 years she was also the sole generalist practicing in the UCSF Viral Hepatitis Clinic. As an educator, she works with medical students and internal medicine residents and lectures nationally on liver disease, especially for primary care audiences.

    Collapse Research 
    Collapse Research Activities and Funding
    Implementation of an Electronic Medical Record Algorithm to Identify and Refer Patients at High Risk of NASH from Primary Care
    Gilead Sciences IN-US-989-5737Jul 1, 2020 - Dec 31, 2022
    Role: PI
    SF CAN Liver Cancer Task Force
    SF CAN - The San Francisco Cancer Initiative Jul 1, 2019
    Role: PI

    Collapse ORNG Applications 
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Assessing Adherence to US LI-RADS Follow-up Recommendations in Vulnerable Patients Undergoing Hepatocellular Carcinoma Surveillance. Radiol Imaging Cancer. 2024 Jan; 6(1):e230118. Choi HH, Kim S, Shum DJ, Huang CY, Shui A, Fox RK, Khalili M. PMID: 38214600; PMCID: PMC10825700.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    2. Underrecognition and Suboptimal Quality of Care for Nonalcoholic Fatty Liver Disease Cirrhosis in Primary Care Patients with Diabetes Mellitus. Am J Med. 2024 Feb; 137(2):172-177.e2. Chu JN, Goldman ML, Brandman D, Sohn JH, Islam K, Ross LA, Fox RK. PMID: 37890572.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Prospective study of a case-finding algorithm to detect NAFLD with advanced fibrosis in primary care patients. Hepatol Commun. 2023 02 01; 7(2):e0024. Fox RK, Chu JN, Goldman ML, Islam KB, Brandman D. PMID: 36724121; PMCID: PMC9894348.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Primary Care Providers and Nonalcoholic Fatty Liver Disease: A Needs Assessment Survey. Dig Dis Sci. 2023 02; 68(2):434-438. Islam KB, Brandman D, Chu JN, Goldman ML, Fox RK. PMID: 36178567; PMCID: PMC9905186.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    5. From Cancer Epidemiology to Policy and Practice: the Role of a Comprehensive Cancer Center. Curr Epidemiol Rep. 2022; 9(1):10-21. Hiatt RA, Sibley A, Venkatesh B, Cheng J, Dixit N, Fox R, Ling P, Nguyen T, Oh D, Palmer NR, Pasick RJ, Potter MB, Somsouk M, Vargas RA, Vijayaraghavan M, Ashworth A. PMID: 35342686; PMCID: PMC8935108.
      View in: PubMed   Mentions: 3  
    6. Hepatitis C Virus Cure and Obesity: Watch the Weight. J Gen Intern Med. 2020 10; 35(10):2836-2837. Mukhtar NA, Fox RK. PMID: 32632793; PMCID: PMC7573049.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. Cancer health disparities in racial/ethnic minorities in the United States. Br J Cancer. 2021 01; 124(2):315-332. Zavala VA, Bracci PM, Carethers JM, Carvajal-Carmona L, Coggins NB, Cruz-Correa MR, Davis M, de Smith AJ, Dutil J, Figueiredo JC, Fox R, Graves KD, Gomez SL, Llera A, Neuhausen SL, Newman L, Nguyen T, Palmer JR, Palmer NR, Pérez-Stable EJ, Piawah S, Rodriquez EJ, Sanabria-Salas MC, Schmit SL, Serrano-Gomez SJ, Stern MC, Weitzel J, Yang JJ, Zabaleta J, Ziv E, Fejerman L. PMID: 32901135; PMCID: PMC7852513.
      View in: PubMed   Mentions: 267     Fields:    Translation:Humans
    8. Randomized feasibility trial of directly observed versus unobserved hepatitis C treatment with ledipasvir-sofosbuvir among people who inject drugs. PLoS One. 2019; 14(6):e0217471. Coffin PO, Santos GM, Behar E, Hern J, Walker J, Matheson T, Kinnard EN, Silvis J, Vittinghoff E, Fox R, Page K. PMID: 31158245; PMCID: PMC6546233.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    9. Aspirin Use and Risk of Hepatocellular Carcinoma in Hepatitis B. JAMA Intern Med. 2019 05 01; 179(5):640-641. Fox RK, Taddei TH, Kaplan DE. PMID: 30882884.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Healthcare Costs Related to Treatment of Hepatocellular Carcinoma Among Veterans With Cirrhosis in the United States. Clin Gastroenterol Hepatol. 2018 Jan; 16(1):106-114.e5. Kaplan DE, Chapko MK, Mehta R, Dai F, Skanderson M, Aytaman A, Baytarian M, D'Addeo K, Fox R, Hunt K, Pocha C, Valderrama A, Taddei TH, VOCAL Study Group. PMID: 28756056; PMCID: PMC5735018.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    11. Association of Provider Specialty and Multidisciplinary Care With Hepatocellular Carcinoma Treatment and Mortality. Gastroenterology. 2017 06; 152(8):1954-1964. Serper M, Taddei TH, Mehta R, D'Addeo K, Dai F, Aytaman A, Baytarian M, Fox R, Hunt K, Goldberg DS, Valderrama A, Kaplan DE, VOCAL Study Group. PMID: 28283421; PMCID: PMC5664153.
      View in: PubMed   Mentions: 102     Fields:    Translation:Humans
    12. Going Viral: Why Eliminating the Burden of Hepatitis C Requires Enhanced Cooperation Between Specialists and Primary Care Providers. Dig Dis Sci. 2016 12; 61(12):3381-3383. Fox R. PMID: 27619392.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    13. Identifying barriers to hepatocellular carcinoma surveillance in a national sample of patients with cirrhosis. Hepatology. 2017 03; 65(3):864-874. Goldberg DS, Taddei TH, Serper M, Mehta R, Dieperink E, Aytaman A, Baytarian M, Fox R, Hunt K, Pedrosa M, Pocha C, Valderrama A, Kaplan DE. PMID: 27531119.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansPHPublic Health
    14. Recalibrating the Child-Turcotte-Pugh Score to Improve Prediction of Transplant-Free Survival in Patients with Cirrhosis. Dig Dis Sci. 2016 11; 61(11):3309-3320. Kaplan DE, Dai F, Skanderson M, Aytaman A, Baytarian M, D'Addeo K, Fox R, Hunt K, Knott A, Mehta R, Pedrosa M, Pocha C, Valderrama A, Taddei T, VOCAL Study Group. PMID: 27405990; PMCID: PMC5067291.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    15. Pharmacologic Therapies in Gastrointestinal Diseases. Med Clin North Am. 2016 Jul; 100(4):827-50. Fox RK, Muniraj T. PMID: 27235617.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    16. Cost-effectiveness of Early Treatment of Hepatitis C Virus Genotype 1 by Stage of Liver Fibrosis in a US Treatment-Naive Population. JAMA Intern Med. 2016 Jan; 176(1):65-73. Chahal HS, Marseille EA, Tice JA, Pearson SD, Ollendorf DA, Fox RK, Kahn JG. PMID: 26595724; PMCID: PMC5144154.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    17. Development and Performance of an Algorithm to Estimate the Child-Turcotte-Pugh Score From a National Electronic Healthcare Database. Clin Gastroenterol Hepatol. 2015 Dec; 13(13):2333-41.e1-6. Kaplan DE, Dai F, Aytaman A, Baytarian M, Fox R, Hunt K, Knott A, Pedrosa M, Pocha C, Mehta R, Duggal M, Skanderson M, Valderrama A, Taddei TH, VOCAL Study Group. PMID: 26188137; PMCID: PMC4655141.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    18. Toward the Effective Co-management of Patients with Cirrhosis by Primary Care Providers and Specialists. Dig Dis Sci. 2015 Sep; 60(9):2576-8. Fox RK. PMID: 25986522.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. The State of Hepatitis C Care in the VA. Fed Pract. 2015 Feb; 32(Suppl 2):20S-24S. Belperio PS, Fox RK, Backus LI. PMID: 30766108; PMCID: PMC6375505.
      View in: PubMed   Mentions:
    20. Falsely Decreased HbA1c in a Type 2 Diabetic Patient Treated with Dapsone. Endocr Pract. 2014 Nov; 20(11):e229-32. Shah AD, Fox RK, Rushakoff RJ. PMID: 25100400; PMCID: PMC4423899.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    21. When to consider liver transplant during the management of chronic liver disease. Med Clin North Am. 2014 Jan; 98(1):153-68. Fox RK. PMID: 24266919.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    22. Hepatitis B--more treatments, more testing, not enough data. J Gen Intern Med. 2011 Mar; 26(3):232-3. Fox RK. PMID: 21267669; PMCID: PMC3043180.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Presentation and outcome of hepatocellular carcinoma in HIV-infected patients: a U.S.-Canadian multicenter study. J Hepatol. 2007 Oct; 47(4):527-37. Bräu N, Fox RK, Xiao P, Marks K, Naqvi Z, Taylor LE, Trikha A, Sherman M, Sulkowski MS, Dieterich DT, Rigsby MO, Wright TL, Hernandez MD, Jain MK, Khatri GK, Sterling RK, Bonacini M, Martyn CA, Aytaman A, Llovet JM, Brown ST, Bini EJ, North American Liver Cancer in HIV Study Group. PMID: 17692986.
      View in: PubMed   Mentions: 87     Fields:    Translation:Humans
    24. Hepatitis C virus infection among prisoners in the California state correctional system. Clin Infect Dis. 2005 Jul 15; 41(2):177-86. Fox RK, Currie SL, Evans J, Wright TL, Tobler L, Phelps B, Busch MP, Page-Shafer KA. PMID: 15983913.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    25. Treatment of acute hepatitis C with interferon alfa-2b. N Engl J Med. 2002 Apr 04; 346(14):1091-2. Seligman HK, Fox RK. PMID: 11936120.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
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