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Richard Tsai, MD, MBA

Title(s)Assistant Clinical Professor, Neurology
SchoolSchool of Medicine
Phone415-353-2057
ORCID ORCID Icon0000-0003-2784-7992 Additional info
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Research 
    Collapse Research Activities and Funding
    Clinical and imaging biomarker evolution of early progressive supranuclear palsy
    NIH/NIA K23AG055688Jul 15, 2017 - Apr 30, 2022
    Role: Principal Investigator

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    Collapse Clinical Trials
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Chen X, Li Y, Wang C, Tang Y, Mok SA, Tsai RM, Rojas JC, Karydas A, Miller BL, Boxer AL, Gestwicki JE, Arkin M, Cuervo AM, Gan L. Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy. Mol Neurodegener. 2020 Jan 06; 15(1):2. PMID: 31906970.
      View in: PubMed
    2. La Joie R, Visani AV, Baker SL, Brown JA, Bourakova V, Cha J, Chaudhary K, Edwards L, Iaccarino L, Janabi M, Lesman-Segev OH, Miller ZA, Perry DC, O'Neil JP, Pham J, Rojas JC, Rosen HJ, Seeley WW, Tsai RM, Miller BL, Jagust WJ, Rabinovici GD. Prospective longitudinal atrophy in Alzheimer's disease correlates with the intensity and topography of baseline tau-PET. Sci Transl Med. 2020 01 01; 12(524). PMID: 31894103.
      View in: PubMed
    3. Tsai RM, Miller Z, Koestler M, Rojas JC, Ljubenkov PA, Rosen HJ, Rabinovici GD, Fagan AM, Cobigo Y, Brown JA, Jung JI, Hare E, Geldmacher DS, Natelson-Love M, McKinley EC, Luong PN, Chuu EL, Powers R, Mumford P, Wolf A, Wang P, Shamloo M, Miller BL, Roberson ED, Boxer AL. Reactions to Multiple Ascending Doses of the Microtubule Stabilizer TPI-287 in Patients With Alzheimer Disease, Progressive Supranuclear Palsy, and Corticobasal Syndrome: A Randomized Clinical Trial. JAMA Neurol. 2019 Nov 11. PMID: 31710340.
      View in: PubMed
    4. Tsai RM, Bejanin A, Lesman-Segev O, LaJoie R, Visani A, Bourakova V, O'Neil JP, Janabi M, Baker S, Lee SE, Perry DC, Bajorek L, Karydas A, Spina S, Grinberg LT, Seeley WW, Ramos EM, Coppola G, Gorno-Tempini ML, Miller BL, Rosen HJ, Jagust W, Boxer AL, Rabinovici GD. 18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes. Alzheimers Res Ther. 2019 01 31; 11(1):13. PMID: 30704514.
      View in: PubMed
    5. Rojas JC, Bang J, Lobach IV, Tsai RM, Rabinovici GD, Miller BL, Boxer AL. CSF neurofilament light chain and phosphorylated tau 181 predict disease progression in PSP. Neurology. 2018 01 23; 90(4):e273-e281. PMID: 29282336.
      View in: PubMed
    6. Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, Jiang H, Sullivan PM, Baufeld C, Wood MW, Sutphen C, McCue L, Xiong C, Del-Aguila JL, Morris JC, Cruchaga C, Fagan AM, Miller BL, Boxer AL, Seeley WW, Butovsky O, Barres BA, Paul SM, Holtzman DM. ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy. Nature. 2017 09 28; 549(7673):523-527. PMID: 28959956.
      View in: PubMed
    7. Tsai RM, Boxer AL. Therapy and clinical trials in frontotemporal dementia: past, present, and future. J Neurochem. 2016 08; 138 Suppl 1:211-21. PMID: 27306957.
      View in: PubMed
    8. Tsai RM, Lobach I, Bang J, Whitwell JL, Senjem ML, Jack CR, Rosen H, Miller B, Boxer AL. Clinical correlates of longitudinal brain atrophy in progressive supranuclear palsy. Parkinsonism Relat Disord. 2016 07; 28:29-35. PMID: 27132501.
      View in: PubMed
    9. Rojas JC, Karydas A, Bang J, Tsai RM, Blennow K, Liman V, Kramer JH, Rosen H, Miller BL, Zetterberg H, Boxer AL. Plasma neurofilament light chain predicts progression in progressive supranuclear palsy. Ann Clin Transl Neurol. 2016 03; 3(3):216-25. PMID: 27042681.
      View in: PubMed
    10. Wang HF, Tan L, Cao L, Zhu XC, Jiang T, Tan MS, Liu Y, Wang C, Tsai RM, Jia JP, Yu JT. Application of the IWG-2 Diagnostic Criteria for Alzheimer's Disease to the ADNI. J Alzheimers Dis. 2016; 51(1):227-36. PMID: 26836176.
      View in: PubMed
    11. Tsai RM, Boxer AL. Treatment of frontotemporal dementia. Curr Treat Options Neurol. 2014 Nov; 16(11):319. PMID: 25238733.
      View in: PubMed
    12. Tsai RM, Leong JK, Dutt S, Chang CC, Lee AK, Chao SZ, Yokoyama JS, Tse M, Kramer JH, Miller BL, Rosen HJ. The Chinese Verbal Learning Test specifically assesses hippocampal state. Am J Alzheimers Dis Other Demen. 2015 Jun; 30(4):412-6. PMID: 25270640.
      View in: PubMed
    13. Tsai RM, Boxer AL. Clinical trials: past, current, and future for atypical Parkinsonian syndromes. Semin Neurol. 2014 Apr; 34(2):225-34. PMID: 24963682.
      View in: PubMed
    14. Buss S, Noone ML, Tsai R, Johnson B, Pradeep VG, Salam KA, Mathuranath PS, Verghese J. Objective cardiac markers in dementia: results from the Kerala-Einstein study. Int J Cardiol. 2013 Jul 31; 167(2):595-6. PMID: 23103139.
      View in: PubMed
    15. Tsai R, Noone M, Johnson B, Pradeep VG, Verghese J. Potentially inappropriate medication use in individuals with mild cognitive impairment: results from the Kerala Einstein Study. J Am Geriatr Soc. 2012 Jul; 60(7):1369-70. PMID: 22788395.
      View in: PubMed