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Robert Lustig, MD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentPediatrics
Address550 16th. Street
San Francisco CA 94158
Phone415-502-8672
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    Collapse Biography 
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    University of California, San FranciscoResidency School of Medicine

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    Collapse Overview
    Robert H. Lustig, M.D. is Professor of Pediatrics in the Division of Endocrinology at University of California, San Francisco, and Director of the Weight Assessment for Teen and Child Health (WATCH) Program at UCSF.

    Dr. Lustig is a neuroendocrinologist, with basic and clinical training relative to hypothalamic development, anatomy, and function. Prior to coming to San Francisco in 2001, he worked at St. Jude Children’s Research Hospital in Memphis, TN. There, he was charged with the endocrine care of many children whose hypothalami had been damaged by brain tumors, or subsequent surgery, radiation, or chemotherapy. Many patients who survived became massively obese. Dr. Lustig theorized that hypothalamic damage led to the inability to sense the hormone leptin, which in turn, led to the starvation response. Since repairing the hypothalamus was not an option, he looked downstream, and noted that these patients had increased activity of the vagus nerve (a manifestation of starvation) which increased insulin secretion. By administering the insulin suppressive agent octreotide, he was able to get them to lose weight; but more remarkably, they started to exercise spontaneously. He then demonstrated the same phenomenon in obese adults without CNS lesions. The universality of these findings has enabled Dr. Lustig to weave these threads together into a novel unifying hypothesis regarding the etiology, prevention, and treatment of the current obesity epidemic. This has led him to explore the specific role of fructose (half of sucrose and high-fructose corn syrup) as a specific mediator of both chronic disease, and continued caloric consumption. His now notorious YouTube video, “Sugar – the bitter truth” continues its popularity with the lay public.

    A native of Brooklyn, NY, Dr. Lustig went to Stuyvesant H.S. in Manhattan, graduated from MIT in 1976, and received his M.D. from Cornell University Medical College in 1980. He completed his pediatric residency at St. Louis Children’s Hospital in 1983, and his clinical fellowship at UCSF in 1984. From there, he spent six years as a post-doctoral fellow and research associate in neuroendocrinology at The Rockefeller University. He has been a faculty member at the University of Wisconsin-Madison, and the University of Tennessee, Memphis. Dr. Lustig has authored 85 peer-reviewed articles and 30 reviews. He has mentored 20 pediatric endocrine fellows, and trained numerous other allied health professionals. He provides endocrinologic support to several protocols of the Children’s Oncology Group. He is the former Chairman of the Ad hoc Obesity Task Force of the Lawson Wilkins Pediatric Endocrine Society, a member of the Pediatric Obesity Practice Guidelines Subcommittee of The Endocrine Society, a member of the Obesity Task Force of the Endocrine Society, a member of the Pediatric Obesity Devices Committee of the U.S. Food and Drug Administration, and a member of the Steering Committee of the International Endocrine Alliance to Combat Obesity. He also consults for several childhood obesity advocacy groups.

    Dr. Lustig lives in San Francisco with his wife and two daughters (ages 10 and 4). Spare time (what little there is) is spent cooking, theater-going, and traveling.


    Collapse Research 
    Collapse Research Activities and Funding
    Metabolic impact of fructose restriction in obese children
    NIH/NIDDK R01DK089216Sep 10, 2010 - Jun 30, 2015
    Role: Co-Principal Investigator
    CRITICAL ANALYSIS OF 16ALPHA-OH-ESTRONE IN BREAST CANCER
    NIH/NCI R55CA058044Sep 30, 1992 - Sep 29, 1994
    Role: Principal Investigator
    BRAIN PEPTIDE AND SEX STEROID METABOLISM
    NIH/NICHD K08HD000703Apr 1, 1987 - Mar 31, 1990
    Role: Principal Investigator
    PEDIATRIC CLINICAL RESEARCH CENTER
    NIH/NCRR M01RR001271Dec 1, 1981 - Mar 31, 2007
    Role: Co-Investigator
    GENERAL CLINICAL RESEARCH CENTER
    NIH M01RR000211Dec 1, 1976 - Nov 30, 2009
    Role: Co-Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000079Dec 1, 1974 - Mar 31, 2009
    Role: Co-Investigator

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    Collapse Featured Publications
    Collapse Global Health
    Collapse Websites
    Collapse In The News
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Chambers JH, Zerofsky M, Lustig RH, Rosenthal P, Perito ER. Diet and Exercise in Pediatric Liver Transplant Recipients: Behaviors and Association with Metabolic Syndrome. J Pediatr Gastroenterol Nutr. 2018 Sep 18. PMID: 30234760.
      View in: PubMed
    2. Berger K, Eskenazi B, Kogut K, Parra K, Lustig RH, Greenspan LC, Holland N, Calafat AM, Ye X, Harley KG. Association of Prenatal Urinary Concentrations of Phthalates and Bisphenol A and Pubertal Timing in Boys and Girls. Environ Health Perspect. 2018 Sep; 126(9):97004. PMID: 30203993.
      View in: PubMed
    3. Gupta N, Lustig RH, Chao C, Vittinghoff E, Andrews H, Leu CS. Thiopurines are negatively associated with anthropometric parameters in pediatric Crohn's disease. World J Gastroenterol. 2018 May 14; 24(18):2036-2046. PMID: 29760546.
      View in: PubMed
    4. Rathore S, Akbari H, Doshi J, Shukla G, Rozycki M, Bilello M, Lustig R, Davatzikos C. Radiomic signature of infiltration in peritumoral edema predicts subsequent recurrence in glioblastoma: implications for personalized radiotherapy planning. J Med Imaging (Bellingham). 2018 Apr; 5(2):021219. PMID: 29531967.
      View in: PubMed
    5. Perito ER, Phelps A, Vase T, Feldstein VA, Lustig RH, Rosenthal P. Subclinical Atherosclerosis in Pediatric Liver Transplant Recipients: Carotid and Aorta Intima-Media Thickness and Their Predictors. J Pediatr. 2018 Feb; 193:119-127.e1. PMID: 29224938.
      View in: PubMed
    6. Vogel J, Both S, Kirk M, Chao HH, Bagatell R, Li Y, Womer R, Balamuth N, Reilly A, Kurtz G, Lustig R, Tochner Z, Hill-Kayser C. Proton therapy for pediatric head and neck malignancies. Pediatr Blood Cancer. 2018 Feb; 65(2). PMID: 29058370.
      View in: PubMed
    7. Lustig RH. Ethical Considerations for Nutrition Counseling About Processed Food-Reply. JAMA Pediatr. 2017 Sep 01; 171(9):914-915. PMID: 28715517.
      View in: PubMed
    8. Stigler FL, Lustig RH, Moser AM. Exercise Type in Dieting Obese Older Adults. N Engl J Med. 2017 08 10; 377(6):598-9. PMID: 28813125.
      View in: PubMed
    9. Vreman RA, Goodell AJ, Rodriguez LA, Porco TC, Lustig RH, Kahn JG. Health and economic benefits of reducing sugar intake in the USA, including effects via non-alcoholic fatty liver disease: a microsimulation model. BMJ Open. 2017 Aug 03; 7(8):e013543. PMID: 28775179.
      View in: PubMed
    10. Perito ER, Vase T, Ramachandran R, Phelps A, Jen KY, Lustig RH, Feldstein VA, Rosenthal P. Hepatic steatosis after pediatric liver transplant. Liver Transpl. 2017 07; 23(7):957-967. PMID: 28426902.
      View in: PubMed
    11. Schwarz JM, Noworolski SM, Erkin-Cakmak A, Korn NJ, Wen MJ, Tai VW, Jones GM, Palii SP, Velasco-Alin M, Pan K, Patterson BW, Gugliucci A, Lustig RH, Mulligan K. Effects of Dietary Fructose Restriction on Liver Fat, De Novo Lipogenesis, and Insulin Kinetics in Children With Obesity. Gastroenterology. 2017 09; 153(3):743-752. PMID: 28579536.
      View in: PubMed
    12. Stigler FL, Lustig RH, Ma JI. Mechanisms, Pathophysiology, and Management of Obesity. N Engl J Med. 2017 04 13; 376(15):1491. PMID: 28402779.
      View in: PubMed
    13. Lustig RH. Processed Food-An Experiment That Failed. JAMA Pediatr. 2017 Mar 01; 171(3):212-214. PMID: 28114671.
      View in: PubMed
    14. Harley KG, Rauch SA, Chevrier J, Kogut K, Parra KL, Trujillo C, Lustig RH, Greenspan LC, Sjödin A, Bradman A, Eskenazi B. Association of prenatal and childhood PBDE exposure with timing of puberty in boys and girls. Environ Int. 2017 03; 100:132-138. PMID: 28089583.
      View in: PubMed
    15. Perito ER, Lustig RH, Rosenthal P. Prediabetes in Pediatric Recipients of Liver Transplant: Mechanism and Risk Factors. J Pediatr. 2017 Mar; 182:223-231.e3. PMID: 28041666.
      View in: PubMed
    16. Eskenazi B, Rauch SA, Tenerelli R, Huen K, Holland NT, Lustig RH, Kogut K, Bradman A, Sjödin A, Harley KG. In utero and childhood DDT, DDE, PBDE and PCBs exposure and sex hormones in adolescent boys: The CHAMACOS study. Int J Hyg Environ Health. 2017 04; 220(2 Pt B):364-372. PMID: 27876543.
      View in: PubMed
    17. Lustig RH. Fructose and Nonalcoholic Fatty Liver Disease J Calif Dent Assoc. 2016 10 13; 44(10):613-17. PMID: 29035477.
      View in: PubMed
    18. Gugliucci A, Lustig RH, Caccavello R, Erkin-Cakmak A, Noworolski SM, Tai VW, Wen MJ, Mulligan K, Schwarz JM. Short-term isocaloric fructose restriction lowers apoC-III levels and yields less atherogenic lipoprotein profiles in children with obesity and metabolic syndrome. Atherosclerosis. 2016 Oct; 253:171-177. PMID: 27451002.
      View in: PubMed
    19. Lustig RH. Sickeningly Sweet: Does Sugar Cause Type 2 Diabetes? Yes. Can J Diabetes. 2016 Aug; 40(4):282-6. PMID: 27216628.
      View in: PubMed
    20. Daubenmier J, Moran PJ, Kristeller J, Acree M, Bacchetti P, Kemeny ME, Dallman M, Lustig RH, Grunfeld C, Nixon DF, Milush JM, Goldman V, Laraia B, Laugero KD, Woodhouse L, Epel ES, Hecht FM. Effects of a mindfulness-based weight loss intervention in adults with obesity: A randomized clinical trial. Obesity (Silver Spring). 2016 Apr; 24(4):794-804. PMID: 26955895; PMCID: PMC4898945 [Available on 04/01/17].
    21. Rodríguez LA, Madsen KA, Cotterman C, Lustig RH. Added sugar intake and metabolic syndrome in US adolescents: cross-sectional analysis of the National Health and Nutrition Examination Survey 2005-2012. Public Health Nutr. 2016 Sep; 19(13):2424-34. PMID: 26932353.
      View in: PubMed
    22. Lustig RH. Response to "Metabolic improvement with fructose restriction: Is it the fructose or the weight loss?". Obesity (Silver Spring). 2016 Mar; 24(3):550. PMID: 26853905.
      View in: PubMed
    23. Mason AE, Epel ES, Aschbacher K, Lustig RH, Acree M, Kristeller J, Cohn M, Dallman M, Moran PJ, Bacchetti P, Laraia B, Hecht FM, Daubenmier J. Reduced reward-driven eating accounts for the impact of a mindfulness-based diet and exercise intervention on weight loss: Data from the SHINE randomized controlled trial. Appetite. 2016 May 01; 100:86-93. PMID: 26867697; PMCID: PMC4799744 [Available on 05/01/17].
    24. Mason AE, Epel ES, Kristeller J, Moran PJ, Dallman M, Lustig RH, Acree M, Bacchetti P, Laraia BA, Hecht FM, Daubenmier J. Effects of a mindfulness-based intervention on mindful eating, sweets consumption, and fasting glucose levels in obese adults: data from the SHINE randomized controlled trial. J Behav Med. 2016 Apr; 39(2):201-13. PMID: 26563148; PMCID: PMC4801689 [Available on 04/01/17].
    25. Vogel J, Ojerholm E, Hollander A, Briola C, Mooij R, Bieda M, Kolker J, Nagda S, Geiger G, Dorsey J, Lustig R, O'Rourke DM, Brem S, Lee J, Alonso-Basanta M. Intracranial control after Cyberknife radiosurgery to the resection bed for large brain metastases. Radiat Oncol. 2015 Oct 31; 10:221. PMID: 26520568; PMCID: PMC4628349.
    26. Lustig RH, Mulligan K, Noworolski SM, Tai VW, Wen MJ, Erkin-Cakmak A, Gugliucci A, Schwarz JM. Isocaloric fructose restriction and metabolic improvement in children with obesity and metabolic syndrome. Obesity (Silver Spring). 2016 Feb; 24(2):453-60. PMID: 26499447.
      View in: PubMed
    27. Lee PD, Lustig RH, Lenders C, Baillargeon J, Wilson DM. INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 PREDICTS INSULIN SENSITIVITY AND INSULIN AREA-UNDER-THE-CURVE IN OBESE, NONDIABETIC ADOLESCENTS. Endocr Pract. 2016 Feb; 22(2):136-42. PMID: 26484407.
      View in: PubMed
    28. Mason AE, Laraia B, Daubenmier J, Hecht FM, Lustig RH, Puterman E, Adler N, Dallman M, Kiernan M, Gearhardt AN, Epel ES. Putting the brakes on the "drive to eat": Pilot effects of naltrexone and reward-based eating on food cravings among obese women. Eat Behav. 2015 Dec; 19:53-6. PMID: 26164674; PMCID: PMC4644449 [Available on 12/01/16].
    29. Mason AE, Lustig RH, Brown RR, Acree M, Bacchetti P, Moran PJ, Dallman M, Laraia B, Adler N, Hecht FM, Daubenmier J, Epel ES. Acute responses to opioidergic blockade as a biomarker of hedonic eating among obese women enrolled in a mindfulness-based weight loss intervention trial. Appetite. 2015 Aug; 91:311-320. PMID: 25931433; PMCID: PMC4485926.
    30. Both S, Shen J, Kirk M, Lin L, Tang S, Alonso-Basanta M, Lustig R, Lin H, Deville C, Hill-Kayser C, Tochner Z, McDonough J. Development and clinical implementation of a universal bolus to maintain spot size during delivery of base of skull pencil beam scanning proton therapy. Int J Radiat Oncol Biol Phys. 2014 Sep 01; 90(1):79-84. PMID: 25195989.
      View in: PubMed
    31. Alkon A, Harley KG, Neilands TB, Tambellini K, Lustig RH, Boyce WT, Eskenazi B. Latino children's body mass index at 2-3.5 years predicts sympathetic nervous system activity at 5 years. Child Obes. 2014 Jun; 10(3):214-24. PMID: 24745554; PMCID: PMC4038992.
    32. Aschbacher K, Kornfeld S, Picard M, Puterman E, Havel PJ, Stanhope K, Lustig RH, Epel E. Chronic stress increases vulnerability to diet-related abdominal fat, oxidative stress, and metabolic risk. Psychoneuroendocrinology. 2014 Aug; 46:14-22. PMID: 24882154; PMCID: PMC4104274.
    33. Ojerholm E, Lee JY, Kolker J, Lustig R, Dorsey JF, Alonso-Basanta M. Gamma Knife radiosurgery to four or more brain metastases in patients without prior intracranial radiation or surgery. Cancer Med. 2014 Jun; 3(3):565-71. PMID: 24510602; PMCID: PMC4101747.
    34. Lin LL, Mick R, Ware J, Metz J, Lustig R, Vapiwala N, Rengan R, Kennedy AR. Phase I randomized double-blind placebo-controlled single-dose safety studies of Bowman-Birk inhibitor concentrate. Oncol Lett. 2014 Apr; 7(4):1151-1158. PMID: 24944684.
      View in: PubMed
    35. Daubenmier J, Lustig RH, Hecht FM, Kristeller J, Woolley J, Adam T, Dallman M, Epel E. A new biomarker of hedonic eating? A preliminary investigation of cortisol and nausea responses to acute opioid blockade. Appetite. 2014 Mar; 74:92-100. PMID: 24291355; PMCID: PMC4125886.
    36. Kumar RJ, Zhai H, Both S, Tochner Z, Lustig R, Hill-Kayser C. Breast cancer screening for childhood cancer survivors after craniospinal irradiation with protons versus x-rays: a dosimetric analysis and review of the literature. J Pediatr Hematol Oncol. 2013 Aug; 35(6):462-7. PMID: 23892352.
      View in: PubMed
    37. Lustig RH. A conversation with Robert H. Lustig, MD, MSL. Interview by Stanford T Shulman. Pediatr Ann. 2013 Jul; 42(7):296. PMID: 23805972.
      View in: PubMed
    38. Hill-Kayser C, Tochner Z, Both S, Lustig R, Reilly A, Balamuth N, Womer R, Maris J, Grupp S, Bagatell R. Proton versus photon radiation therapy for patients with high-risk neuroblastoma: the need for a customized approach. Pediatr Blood Cancer. 2013 Oct; 60(10):1606-11. PMID: 23737005.
      View in: PubMed
    39. Perito ER, Tsai PM, Hawley S, Lustig RH, Feldstein VA. Targeted hepatic sonography during clinic visits for detection of fatty liver in overweight children: a pilot study. J Ultrasound Med. 2013 Apr; 32(4):637-43. PMID: 23525389.
      View in: PubMed
    40. Perito ER, Rodriguez LA, Lustig RH. Dietary treatment of nonalcoholic steatohepatitis. Curr Opin Gastroenterol. 2013 Mar; 29(2):170-6. PMID: 23283181.
      View in: PubMed
    41. Lustig RH. Fructose: it's "alcohol without the buzz". Adv Nutr. 2013 Mar 01; 4(2):226-35. PMID: 23493539; PMCID: PMC3649103.
    42. Basu S, Yoffe P, Hills N, Lustig RH. The relationship of sugar to population-level diabetes prevalence: an econometric analysis of repeated cross-sectional data. PLoS One. 2013; 8(2):e57873. PMID: 23460912; PMCID: PMC3584048.
    43. Harley KG, Aguilar Schall R, Chevrier J, Tyler K, Aguirre H, Bradman A, Holland NT, Lustig RH, Calafat AM, Eskenazi B. Prenatal and postnatal bisphenol A exposure and body mass index in childhood in the CHAMACOS cohort. Environ Health Perspect. 2013 Apr; 121(4):514-20. PMID: 23416456; PMCID: PMC3620748.
    44. Weiss R, Bremer AA, Lustig RH. What is metabolic syndrome, and why are children getting it? Ann N Y Acad Sci. 2013 Apr; 1281:123-40. PMID: 23356701; PMCID: PMC3715098.
    45. Volberg V, Harley KG, Aguilar RS, Rosas LG, Huen K, Yousefi P, Davé V, Phan N, Lustig RH, Eskenazi B, Holland N. Associations between perinatal factors and adiponectin and leptin in 9-year-old Mexican-American children. Pediatr Obes. 2013 Dec; 8(6):454-63. PMID: 23325579; PMCID: PMC3633700.
    46. Gupta N, Lustig RH, Kohn MA, Vittinghoff E. Determination of bone age in pediatric patients with Crohn's disease should become part of routine care. Inflamm Bowel Dis. 2013 Jan; 19(1):61-5. PMID: 22552908.
      View in: PubMed
    47. Campen CJ, Kranick SM, Kasner SE, Kessler SK, Zimmerman RA, Lustig R, Phillips PC, Storm PB, Smith SE, Ichord R, Fisher MJ. Cranial irradiation increases risk of stroke in pediatric brain tumor survivors. Stroke. 2012 Nov; 43(11):3035-40. PMID: 22968468; PMCID: PMC3492057.
    48. Cooper JS, Zhang Q, Pajak TF, Forastiere AA, Jacobs J, Saxman SB, Kish JA, Kim HE, Cmelak AJ, Rotman M, Lustig R, Ensley JF, Thorstad W, Schultz CJ, Yom SS, Ang KK. Long-term follow-up of the RTOG 9501/intergroup phase III trial: postoperative concurrent radiation therapy and chemotherapy in high-risk squamous cell carcinoma of the head and neck. Int J Radiat Oncol Biol Phys. 2012 Dec 01; 84(5):1198-205. PMID: 22749632; PMCID: PMC3465463.
    49. Gupta N, Lustig RH, Kohn MA, Vittinghoff E. Menarche in pediatric patients with Crohn's disease. Dig Dis Sci. 2012 Nov; 57(11):2975-81. PMID: 22744430.
      View in: PubMed
    50. Tomiyama AJ, Schamarek I, Lustig RH, Kirschbaum C, Puterman E, Havel PJ, Epel ES. Leptin concentrations in response to acute stress predict subsequent intake of comfort foods. Physiol Behav. 2012 Aug 20; 107(1):34-9. PMID: 22579988; PMCID: PMC3409346.
    51. Lustig RH. Diabetes and dietary fibre: directive or distraction? Clin Exp Ophthalmol. 2012 Apr; 40(3):230-1. PMID: 22490112.
      View in: PubMed
    52. Bremer AA, Mietus-Snyder M, Lustig RH. Toward a unifying hypothesis of metabolic syndrome. Pediatrics. 2012 Mar; 129(3):557-70. PMID: 22351884; PMCID: PMC3289531.
    53. Lustig RH, Schmidt LA, Brindis CD. Public health: The toxic truth about sugar. Nature. 2012 Feb 01; 482(7383):27-9. PMID: 22297952.
      View in: PubMed
    54. Rhodes ET, Goran MI, Lieu TA, Lustig RH, Prosser LA, Songer TJ, Weigensberg MJ, Weinstock RS, Gonzalez T, Rawluk K, Zoghbi RM, Ludwig DS, Laffel LM. Health-related quality of life in adolescents with or at risk for type 2 diabetes mellitus. J Pediatr. 2012 Jun; 160(6):911-7. PMID: 22217471; PMCID: PMC4793715.
    55. Bremer AA, Lustig RH. Effects of sugar-sweetened beverages on children. Pediatr Ann. 2012 Jan; 41(1):26-30. PMID: 22224718.
      View in: PubMed
    56. Suneja G, Alonso-Basanta M, Lustig R, Lee JY, Bekelman JE. Postoperative radiation therapy for low-grade glioma: patterns of care between 1998 and 2006. Cancer. 2012 Aug 01; 118(15):3735-42. PMID: 22180333.
      View in: PubMed
    57. Lustig RH. Hypothalamic obesity after craniopharyngioma: mechanisms, diagnosis, and treatment. Front Endocrinol (Lausanne). 2011; 2:60. PMID: 22654817; PMCID: PMC3356006.
    58. Merchant TE, Rose SR, Bosley C, Wu S, Xiong X, Lustig RH. Growth hormone secretion after conformal radiation therapy in pediatric patients with localized brain tumors. J Clin Oncol. 2011 Dec 20; 29(36):4776-80. PMID: 22042949; PMCID: PMC3255988.
    59. Daubenmier J, Kristeller J, Hecht FM, Maninger N, Kuwata M, Jhaveri K, Lustig RH, Kemeny M, Karan L, Epel E. Mindfulness Intervention for Stress Eating to Reduce Cortisol and Abdominal Fat among Overweight and Obese Women: An Exploratory Randomized Controlled Study. J Obes. 2011; 2011:651936. PMID: 21977314; PMCID: PMC3184496.
    60. Garber AK, Lustig RH. Is fast food addictive? Curr Drug Abuse Rev. 2011 Sep; 4(3):146-62. PMID: 21999689.
      View in: PubMed
    61. Wojcicki JM, Holbrook K, Lustig RH, Caughey AB, Muñoz RF, Heyman MB. Infant formula, tea, and water supplementation of latino infants at 4-6 weeks postpartum. J Hum Lact. 2011 May; 27(2):122-30. PMID: 21527796; PMCID: PMC3139537.
    62. Sharma S, Lustig RH, Fleming SE. Identifying metabolic syndrome in African American children using fasting HOMA-IR in place of glucose. Prev Chronic Dis. 2011 May; 8(3):A64. PMID: 21477504; PMCID: PMC3103569.
    63. Chen JL, Weiss S, Heyman MB, Lustig R. Risk factors for obesity and high blood pressure in Chinese American children: maternal acculturation and children's food choices. J Immigr Minor Health. 2011 Apr; 13(2):268-75. PMID: 19757055; PMCID: PMC2929294.
    64. Chen JL, Weiss S, Heyman MB, Cooper B, Lustig RH. The efficacy of the web-based childhood obesity prevention program in Chinese American adolescents (Web ABC study). J Adolesc Health. 2011 Aug; 49(2):148-54. PMID: 21783046; PMCID: PMC3143380.
    65. Wojcicki JM, Holbrook K, Lustig RH, Epel E, Caughey AB, Muñoz RF, Shiboski SC, Heyman MB. Chronic maternal depression is associated with reduced weight gain in latino infants from birth to 2 years of age. PLoS One. 2011 Feb 23; 6(2):e16737. PMID: 21373638; PMCID: PMC3044151.
    66. Abrams RA, Winter KA, Regine WF, Safran H, Hoffman JP, Lustig R, Konski AA, Benson AB, Macdonald JS, Rich TA, Willett CG. Failure to adhere to protocol specified radiation therapy guidelines was associated with decreased survival in RTOG 9704--a phase III trial of adjuvant chemotherapy and chemoradiotherapy for patients with resected adenocarcinoma of the pancreas. Int J Radiat Oncol Biol Phys. 2012 Feb 01; 82(2):809-16. PMID: 21277694; PMCID: PMC3133855.
    67. Gupta N, Lustig RH, Kohn MA, McCracken M, Vittinghoff E. Sex differences in statural growth impairment in Crohn's disease: role of IGF-1. Inflamm Bowel Dis. 2011 Nov; 17(11):2318-25. PMID: 21287667; PMCID: PMC3136638.
    68. Nguyen S, Lustig RH. Just a spoonful of sugar helps the blood pressure go up. Expert Rev Cardiovasc Ther. 2010 Nov; 8(11):1497-9. PMID: 21090921.
      View in: PubMed
    69. Lustig RH. Fructose: metabolic, hedonic, and societal parallels with ethanol. J Am Diet Assoc. 2010 Sep; 110(9):1307-21. PMID: 20800122.
      View in: PubMed
    70. Chen JL, Weiss SJ, Heyman MB, Cooper B, Lustig RH. The Active Balance Childhood program for improving coping and quality of life in Chinese American children. Nurs Res. 2010 Jul-Aug; 59(4):270-9. PMID: 20585223; PMCID: PMC2943857.
    71. Lim JS, Mietus-Snyder M, Valente A, Schwarz JM, Lustig RH. The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome. Nat Rev Gastroenterol Hepatol. 2010 May; 7(5):251-64. PMID: 20368739.
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    72. Sharma S, Roberts LS, Lustig RH, Fleming SE. Carbohydrate intake and cardiometabolic risk factors in high BMI African American children. Nutr Metab (Lond). 2010 Feb 09; 7(1):10. PMID: 20181134; PMCID: PMC2830201.
    73. Wilson DM, Abrams SH, Aye T, Lee PD, Lenders C, Lustig RH, Osganian SV, Feldman HA. Metformin extended release treatment of adolescent obesity: a 48-week randomized, double-blind, placebo-controlled trial with 48-week follow-up. Arch Pediatr Adolesc Med. 2010 Feb; 164(2):116-23. PMID: 20124139; PMCID: PMC3499098.
    74. Raman A, Ritchie LD, Lustig RH, Fitch MD, Hudes ML, Fleming SE. Insulin resistance is improved in overweight African American boys but not in girls following a one-year multidisciplinary community intervention program. J Pediatr Endocrinol Metab. 2010 Jan-Feb; 23(1-2):109-20. PMID: 20432814.
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    75. Chen JL, Weiss S, Heyman MB, Lustig RH. Efficacy of a child-centred and family-based program in promoting healthy weight and healthy behaviors in Chinese American children: a randomized controlled study. J Public Health (Oxf). 2010 Jun; 32(2):219-29. PMID: 19933120; PMCID: PMC2875985.
    76. Sharma S, Roberts LS, Hudes ML, Lustig RH, Fleming SE. Macronutrient intakes and cardio metabolic risk factors in high BMI African American children. Nutr Metab (Lond). 2009 Oct 13; 6:41. PMID: 19825190; PMCID: PMC2770039.
    77. Madsen KA, Garber AK, Mietus-Snyder ML, Orrell-Valente JK, Tran CT, Wlasiuk L, Matos RI, Neuhaus J, Lustig RH. A clinic-based lifestyle intervention for pediatric obesity: efficacy and behavioral and biochemical predictors of response. J Pediatr Endocrinol Metab. 2009 Sep; 22(9):805-14. PMID: 19960890; PMCID: PMC2921937.
    78. Johnson RK, Appel LJ, Brands M, Howard BV, Lefevre M, Lustig RH, Sacks F, Steffen LM, Wylie-Rosett J. Dietary sugars intake and cardiovascular health: a scientific statement from the American Heart Association. Circulation. 2009 Sep 15; 120(11):1011-20. PMID: 19704096.
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    79. Merchant TE, Conklin HM, Wu S, Lustig RH, Xiong X. Late effects of conformal radiation therapy for pediatric patients with low-grade glioma: prospective evaluation of cognitive, endocrine, and hearing deficits. J Clin Oncol. 2009 Aug 01; 27(22):3691-7. PMID: 19581535; PMCID: PMC2799064.
    80. Raman A, Lustig RH, Fitch M, Fleming SE. Accuracy of self-assessed Tanner staging against hormonal assessment of sexual maturation in overweight African-American children. J Pediatr Endocrinol Metab. 2009 Jul; 22(7):609-22. PMID: 19774842.
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    81. Nguyen S, Choi HK, Lustig RH, Hsu CY. Sugar-sweetened beverages, serum uric acid, and blood pressure in adolescents. J Pediatr. 2009 Jun; 154(6):807-13. PMID: 19375714; PMCID: PMC2727470.
    82. Gasparetto EL, Pawlak MA, Patel SH, Huse J, Woo JH, Krejza J, Rosenfeld MR, O'Rourke DM, Lustig R, Melhem ER, Wolf RL. Posttreatment recurrence of malignant brain neoplasm: accuracy of relative cerebral blood volume fraction in discriminating low from high malignant histologic volume fraction. Radiology. 2009 Mar; 250(3):887-96. PMID: 19244052.
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    83. Steinberger J, Daniels SR, Eckel RH, Hayman L, Lustig RH, McCrindle B, Mietus-Snyder ML. Progress and challenges in metabolic syndrome in children and adolescents: a scientific statement from the American Heart Association Atherosclerosis, Hypertension, and Obesity in the Young Committee of the Council on Cardiovascular Disease in the Young; Council on Cardiovascular Nursing; and Council on Nutrition, Physical Activity, and Metabolism. Circulation. 2009 Feb 03; 119(4):628-47. PMID: 19139390.
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    84. Braithwaite D, Moore DH, Lustig RH, Epel ES, Ong KK, Rehkopf DH, Wang MC, Miller SM, Hiatt RA. Socioeconomic status in relation to early menarche among black and white girls. Cancer Causes Control. 2009 Jul; 20(5):713-20. PMID: 19107561.
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    85. Lustig RH. Hypothalamic obesity: causes, consequences, treatment. Pediatr Endocrinol Rev. 2008 Dec; 6(2):220-7. PMID: 19202508.
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    86. Kaufman FR, Lustig RH, Vigersky R. Patient guide to the prevention and management of pediatric obesity. J Clin Endocrinol Metab. 2008 Dec; 93(12):2 p following 4989. PMID: 19097260.
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    87. August GP, Caprio S, Fennoy I, Freemark M, Kaufman FR, Lustig RH, Silverstein JH, Speiser PW, Styne DM, Montori VM. Prevention and treatment of pediatric obesity: an endocrine society clinical practice guideline based on expert opinion. J Clin Endocrinol Metab. 2008 Dec; 93(12):4576-99. PMID: 18782869.
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    88. Raman A, Fitch MD, Hudes ML, Lustig RH, Murray CB, Ikeda JP, Fleming SE. Baseline correlates of insulin resistance in inner city high-BMI African-American children. Obesity (Silver Spring). 2008 Sep; 16(9):2039-45. PMID: 19186328.
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    89. Lustig R, Mikkelsen T, Lesser G, Grossman S, Ye X, Desideri S, Fisher J, Wright J. Phase II preradiation R115777 (tipifarnib) in newly diagnosed GBM with residual enhancing disease. Neuro Oncol. 2008 Dec; 10(6):1004-9. PMID: 18725460; PMCID: PMC2718997.
    90. Chen JL, Weiss S, Heyman MB, Vittinghoff E, Lustig R. Pilot study of an individually tailored educational program by mail to promote healthy weight in Chinese American children. J Spec Pediatr Nurs. 2008 Jul; 13(3):212-22. PMID: 18638051; PMCID: PMC2877702.
    91. Lustig RH. Which comes first? The obesity or the insulin? The behavior or the biochemistry? J Pediatr. 2008 May; 152(5):601-2. PMID: 18410757.
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    92. Accurso A, Bernstein RK, Dahlqvist A, Draznin B, Feinman RD, Fine EJ, Gleed A, Jacobs DB, Larson G, Lustig RH, Manninen AH, McFarlane SI, Morrison K, Nielsen JV, Ravnskov U, Roth KS, Silvestre R, Sowers JR, Sundberg R, Volek JS, Westman EC, Wood RJ, Wortman J, Vernon MC. Dietary carbohydrate restriction in type 2 diabetes mellitus and metabolic syndrome: time for a critical appraisal. Nutr Metab (Lond). 2008 Apr 08; 5:9. PMID: 18397522; PMCID: PMC2359752.
    93. Bremer AA, Ranadive S, Lustig RH. Outpatient transition of an infant with permanent neonatal diabetes due to a KCNJ11 activating mutation from subcutaneous insulin to oral glyburide. Pediatr Diabetes. 2008 Jun; 9(3 Pt 1):236-9. PMID: 18221420.
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    94. Velásquez-Mieyer PA, Cowan PA, Pérez-Faustinelli S, Nieto-Martínez R, Villegas-Barreto C, Tolley EA, Lustig RH, Alpert BS. Racial disparity in glucagon-like peptide 1 and inflammation markers among severely obese adolescents. Diabetes Care. 2008 Apr; 31(4):770-5. PMID: 18184905.
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    95. Mietus-Snyder ML, Lustig RH. Childhood obesity: adrift in the "limbic triangle". Annu Rev Med. 2008; 59:147-62. PMID: 17845135.
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    96. Jasik CB, Lustig RH. Adolescent obesity and puberty: the "perfect storm". Ann N Y Acad Sci. 2008; 1135:265-79. PMID: 18574233.
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    97. Pardee PE, Norman GJ, Lustig RH, Preud'homme D, Schwimmer JB. Television viewing and hypertension in obese children. Am J Prev Med. 2007 Dec; 33(6):439-43. PMID: 18022058.
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    98. Evans SM, Du KL, Chalian AA, Mick R, Zhang PJ, Hahn SM, Quon H, Lustig R, Weinstein GS, Koch CJ. Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome. Int J Radiat Oncol Biol Phys. 2007 Nov 15; 69(4):1024-31. PMID: 17967299; PMCID: PMC2737259.
    99. Welsh J, Sanan A, Gabayan AJ, Green SB, Lustig R, Burri S, Kwong E, Stea B. GliaSite brachytherapy boost as part of initial treatment of glioblastoma multiforme: a retrospective multi-institutional pilot study. Int J Radiat Oncol Biol Phys. 2007 May 01; 68(1):159-65. PMID: 17331666.
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    100. Cheung CC, Lustig RH. Pituitary development and physiology. Pituitary. 2007; 10(4):335-50. PMID: 17638086.
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    101. Madsen KA, Yen S, Wlasiuk L, Newman TB, Lustig R. Feasibility of a dance videogame to promote weight loss among overweight children and adolescents. Arch Pediatr Adolesc Med. 2007 Jan; 161(1):105-7. PMID: 17199076.
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    102. Lustig RH. The 'skinny' on childhood obesity: how our western environment starves kids' brains. Pediatr Ann. 2006 Dec; 35(12):898-902, 905-7. PMID: 17236437.
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    103. Sunar U, Quon H, Durduran T, Zhang J, Du J, Zhou C, Yu G, Choe R, Kilger A, Lustig R, Loevner L, Nioka S, Chance B, Yodh AG. Noninvasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study. J Biomed Opt. 2006 Nov-Dec; 11(6):064021. PMID: 17212544.
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    104. Lustig RH. Childhood obesity: behavioral aberration or biochemical drive? Reinterpreting the First Law of Thermodynamics. Nat Clin Pract Endocrinol Metab. 2006 Aug; 2(8):447-58. PMID: 16932334.
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    105. Gabayan AJ, Green SB, Sanan A, Jenrette J, Schultz C, Papagikos M, Tatter SP, Patel A, Amin P, Lustig R, Bastin KT, Watson G, Burri S, Stea B. GliaSite brachytherapy for treatment of recurrent malignant gliomas: a retrospective multi-institutional analysis. Neurosurgery. 2006 Apr; 58(4):701-9; discussion 701-9. PMID: 16575334.
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    106. Lustig RH, Mietus-Snyder ML, Bacchetti P, Lazar AA, Velasquez-Mieyer PA, Christensen ML. Insulin dynamics predict body mass index and z-score response to insulin suppression or sensitization pharmacotherapy in obese children. J Pediatr. 2006 Jan; 148(1):23-9. PMID: 16423593; PMCID: PMC1550350.
    107. Lustig RH. Pediatric endocrine disorders of energy balance. Rev Endocr Metab Disord. 2005 Dec; 6(4):245-60. PMID: 16311943.
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    108. Rose SR, Danish RK, Kearney NS, Schreiber RE, Lustig RH, Burghen GA, Hudson MM. ACTH deficiency in childhood cancer survivors. Pediatr Blood Cancer. 2005 Nov; 45(6):808-13. PMID: 15700255.
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    109. Isganaitis E, Lustig RH. Fast food, central nervous system insulin resistance, and obesity. Arterioscler Thromb Vasc Biol. 2005 Dec; 25(12):2451-62. PMID: 16166564.
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    110. Feldman BJ, Rosenthal SM, Vargas GA, Fenwick RG, Huang EA, Matsuda-Abedini M, Lustig RH, Mathias RS, Portale AA, Miller WL, Gitelman SE. Nephrogenic syndrome of inappropriate antidiuresis. N Engl J Med. 2005 May 05; 352(18):1884-90. PMID: 15872203.
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    111. Preeyasombat C, Bacchetti P, Lazar AA, Lustig RH. Racial and etiopathologic dichotomies in insulin hypersecretion and resistance in obese children. J Pediatr. 2005 Apr; 146(4):474-81. PMID: 15812449.
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    112. Speiser PW, Rudolf MC, Anhalt H, Camacho-Hubner C, Chiarelli F, Eliakim A, Freemark M, Gruters A, Hershkovitz E, Iughetti L, Krude H, Latzer Y, Lustig RH, Pescovitz OH, Pinhas-Hamiel O, Rogol AD, Shalitin S, Sultan C, Stein D, Vardi P, Werther GA, Zadik Z, Zuckerman-Levin N, Hochberg Z. Childhood obesity. J Clin Endocrinol Metab. 2005 Mar; 90(3):1871-87. PMID: 15598688.
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    113. Souhami L, Seiferheld W, Brachman D, Podgorsak EB, Werner-Wasik M, Lustig R, Schultz CJ, Sause W, Okunieff P, Buckner J, Zamorano L, Mehta MP, Curran WJ. Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: report of Radiation Therapy Oncology Group 93-05 protocol. Int J Radiat Oncol Biol Phys. 2004 Nov 01; 60(3):853-60. PMID: 15465203.
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    114. Metz JM, Smith D, Mick R, Lustig R, Mitchell J, Cherakuri M, Glatstein E, Hahn SM. A phase I study of topical Tempol for the prevention of alopecia induced by whole brain radiotherapy. Clin Cancer Res. 2004 Oct 01; 10(19):6411-7. PMID: 15475427.
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    115. Maity A, Shu HK, Tan JE, Ruffer J, Sutton LN, Tochner Z, Lustig R. Treatment of pediatric intracranial arteriovenous malformations with linear-accelerator-based stereotactic radiosurgery: the University of Pennsylvania experience. Pediatr Neurosurg. 2004 Sep-Oct; 40(5):207-14. PMID: 15689641.
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    116. Merchant TE, Mulhern RK, Krasin MJ, Kun LE, Williams T, Li C, Xiong X, Khan RB, Lustig RH, Boop FA, Sanford RA. Preliminary results from a phase II trial of conformal radiation therapy and evaluation of radiation-related CNS effects for pediatric patients with localized ependymoma. J Clin Oncol. 2004 Aug 01; 22(15):3156-62. PMID: 15284268.
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    117. Machtay M, Rosenthal DI, Chalian AA, Lustig R, Hershock D, Miller L, Weinstein GS, Weber RS. Pilot study of postoperative reirradiation, chemotherapy, and amifostine after surgical salvage for recurrent head-and-neck cancer. Int J Radiat Oncol Biol Phys. 2004 May 01; 59(1):72-7. PMID: 15093901.
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    118. Armstrong CL, Gyato K, Awadalla AW, Lustig R, Tochner ZA. A critical review of the clinical effects of therapeutic irradiation damage to the brain: the roots of controversy. Neuropsychol Rev. 2004 Mar; 14(1):65-86. PMID: 15260139.
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    119. Lustig RH. Optimizing growth hormone efficacy: an evidence-based analysis. Horm Res. 2004; 62 Suppl 3:93-7. PMID: 15539806.
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    120. Rose SR, Schreiber RE, Kearney NS, Lustig RH, Danish RK, Burghen GA, Hudson MM. Hypothalamic dysfunction after chemotherapy. J Pediatr Endocrinol Metab. 2004 Jan; 17(1):55-66. PMID: 14960022.
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    121. Lustig RH, Hinds PS, Ringwald-Smith K, Christensen RK, Kaste SC, Schreiber RE, Rai SN, Lensing SY, Wu S, Xiong X. Octreotide therapy of pediatric hypothalamic obesity: a double-blind, placebo-controlled trial. J Clin Endocrinol Metab. 2003 Jun; 88(6):2586-92. PMID: 12788859.
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    122. Lustig RH. Autonomic dysfunction of the beta-cell and the pathogenesis of obesity. Rev Endocr Metab Disord. 2003 Mar; 4(1):23-32. PMID: 12618557.
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    123. Lustig RH, Post SR, Srivannaboon K, Rose SR, Danish RK, Burghen GA, Xiong X, Wu S, Merchant TE. Risk factors for the development of obesity in children surviving brain tumors. J Clin Endocrinol Metab. 2003 Feb; 88(2):611-6. PMID: 12574189.
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    124. Merchant TE, Williams T, Smith JM, Rose SR, Danish RK, Burghen GA, Kun LE, Lustig RH. Preirradiation endocrinopathies in pediatric brain tumor patients determined by dynamic tests of endocrine function. Int J Radiat Oncol Biol Phys. 2002 Sep 01; 54(1):45-50. PMID: 12182973.
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    125. Leung W, Rose SR, Zhou Y, Hancock ML, Burstein S, Schriock EA, Lustig R, Danish RK, Evans WE, Hudson MM, Pui CH. Outcomes of growth hormone replacement therapy in survivors of childhood acute lymphoblastic leukemia. J Clin Oncol. 2002 Jul 01; 20(13):2959-64. PMID: 12089225.
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    126. Merchant TE, Kiehna EN, Sanford RA, Mulhern RK, Thompson SJ, Wilson MW, Lustig RH, Kun LE. Craniopharyngioma: the St. Jude Children's Research Hospital experience 1984-2001. Int J Radiat Oncol Biol Phys. 2002 Jul 01; 53(3):533-42. PMID: 12062594.
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    127. Boehm BO, Lustig RH. Use of somatostatin receptor ligands in obesity and diabetic complications. Best Pract Res Clin Gastroenterol. 2002 Jun; 16(3):493-509. PMID: 12079271.
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    128. Merchant TE, Goloubeva O, Pritchard DL, Gaber MW, Xiong X, Danish RK, Lustig RH. Radiation dose-volume effects on growth hormone secretion. Int J Radiat Oncol Biol Phys. 2002 Apr 01; 52(5):1264-70. PMID: 11955738.
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