Robert Owen, MD

TitleClinical Professor
SchoolUCSF School of Medicine
Address513 Parnassus Avenue
San Francisco CA 94117
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency Gastroenterology

    Collapse Overview 
    Collapse Overview
    Career Narrative
    My clinical work includes gastroenterology, general internal medicine, intestinal infectious diseases, HIV infection and AIDS, travel medicine and medical effects of military occupational environmental exposures, especially in Persian Gulf, Afghanistan, Vietnam (Agent Orange) and Ionizing Radiation exposed veterans. I am also a Compensation & Pension examiner for the Department of Veterans Affairs.

    Research Interests:
    My work has involved delineation of the structure and function of Peyer's patches and other mucosal
    lymphoid organs, using ultrastructure, immunohistology, morphometric analysis, and FACS analysis in
    immunocompetent and immunodeficient animal models. Clinical research interests include diarrhea and
    intestinal infections, identifying the role of opportunistic pathogens including Giardia, Cryptosporidia,
    Microsporidia and Mycobacterium avium.

    Collapse Research 
    Collapse Research Activities and Funding
    NIH/NIDDK R01DK038550May 1, 1987 - Jun 30, 1996
    Role: Co-Principal Investigator
    NIH P01AM033004Dec 1, 1983 - Nov 30, 1986
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Global Health

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Wang QP, Wu ZD, Wei J, Owen R, Lun ZR. Human Angiostrongylus cantonensis: an update. Eur J Clin Microbiol Infect Dis. 2012 Apr; 31(4):389-95. PMID: 21725905.
      View in: PubMed
    2. Schmucker DL, Owen R, Outenreath R, Thoreux K. Basis for the age-related decline in intestinal mucosal immunity. Clin Dev Immunol. 2003 Jun-Dec; 10(2-4):167-72. PMID: 14768948; PMCID: PMC2485420.
    3. Schmucker DL, Thoreux K, Owen R. Aging impairs intestinal immunity. Mech Ageing Dev. 2001 Sep 15; 122(13):1397-411. PMID: 11470129.
      View in: PubMed
    4. Thoreux K, Owen R, Schmucker DL. Intestinal lymphocyte number, migration and antibody secretion in young and old rats. Immunology. 2000 Sep; 101(1):161-7. PMID: 11012768; PMCID: PMC2327049.
    5. Owen R. Uptake and transport of intestinal macromolecules and microorganisms by M cells in Peyer's patches--a personal and historical perspective. Semin Immunol. 1999 Jun; 11(3):157-63. PMID: 10381861.
      View in: PubMed
    6. Koch J, Owen R. Small intestine pathogens in AIDS: conventional and opportunistic. Gastrointest Endosc Clin N Am. 1998 Oct; 8(4):869-88. PMID: 9730937.
      View in: PubMed
    7. Owen R. M cells as portals of entry for HIV. Pathobiology. 1998; 66(3-4):141-4. PMID: 9693315.
      View in: PubMed
    8. Owen R. Mid-life crisis for M cells. Gut. 1998 Jan; 42(1):11-2. PMID: 9505877; PMCID: PMC1726977.
    9. Schmucker DL, Heyworth MF, Owen R, Daniels CK. Impact of aging on gastrointestinal mucosal immunity. Dig Dis Sci. 1996 Jun; 41(6):1183-93. PMID: 8654151.
      View in: PubMed
    10. Fujimura Y, Owen R. M cells as portals of infection: clinical and pathophysiological aspects. Infect Agents Dis. 1996 Jun; 5(3):144-56. PMID: 8805077.
      View in: PubMed
    11. Owen R. M cells--entryways of opportunity for enteropathogens. J Exp Med. 1994 Jul 01; 180(1):7-9. PMID: 8006602; PMCID: PMC2191581.
    12. Chui DW, Owen R. AIDS and the gut. J Gastroenterol Hepatol. 1994 May-Jun; 9(3):291-303. PMID: 8054532.
      View in: PubMed
    13. Kato T, Owen R. Absence of EGF receptors and of EGF uptake in Peyer's patch dome epithelium. Adv Exp Med Biol. 1994; 355:295-301. PMID: 7709839.
      View in: PubMed
    14. Ohtsuka A, Piazza AJ, Ermak TH, Owen R. Correlation of extracellular matrix components with the cytoarchitecture of mouse Peyer's patches. Cell Tissue Res. 1992 Sep; 269(3):403-10. PMID: 1423508.
      View in: PubMed
    15. Owen R, Piazza AJ, Ermak TH. Ultrastructural and cytoarchitectural features of lymphoreticular organs in the colon and rectum of adult BALB/c mice. Am J Anat. 1991 Jan; 190(1):10-8. PMID: 1984672.
      View in: PubMed
    16. Owen R, Ermak TH. Structural specializations for antigen uptake and processing in the digestive tract. Springer Semin Immunopathol. 1990; 12(2-3):139-52. PMID: 2205936.
      View in: PubMed
    17. Ermak TH, Steger HJ, Strober S, Owen R. M cells and granular mononuclear cells in Peyer's patch domes of mice depleted of their lymphocytes by total lymphoid irradiation. Am J Pathol. 1989 Mar; 134(3):529-37. PMID: 2923183; PMCID: PMC1879537.
    18. Pappo J, Owen R. Absence of secretory component expression by epithelial cells overlying rabbit gut-associated lymphoid tissue. Gastroenterology. 1988 Nov; 95(5):1173-7. PMID: 2458985.
      View in: PubMed
    19. Ermak TH, Steger HJ, Owen R, Strober S. Depletion and repopulation of lymphocytes in Peyer's patches of mice after total lymphoid irradiation. Lab Invest. 1988 Nov; 59(5):591-7. PMID: 2903270.
      View in: PubMed
    20. Pappo J, Steger HJ, Owen R. Differential adherence of epithelium overlying gut-associated lymphoid tissue. An ultrastructural study. Lab Invest. 1988 Jun; 58(6):692-7. PMID: 3379916.
      View in: PubMed
    21. Ermak TH, Steger HJ, Owen R, Heyworth MF. Modulation of lymphocyte subsets in Peyer's patches of mice treated with monoclonal antibody against helper T-cells. J Histochem Cytochem. 1988 Apr; 36(4):417-23. PMID: 2964470.
      View in: PubMed
    22. Owen R, Cray WC, Ermak TH, Pierce NF. Bacterial characteristics and follicle surface structure: their roles in Peyer's patch uptake and transport of Vibrio cholerae. Adv Exp Med Biol. 1988; 237:705-15. PMID: 3254071.
      View in: PubMed
    23. Ermak TH, Owen R. Phenotype and distribution of T lymphocytes in Peyer's patches of athymic mice. Histochemistry. 1987; 87(4):321-5. PMID: 3319975.
      View in: PubMed
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