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Roland Wu, MD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    University of California San FranciscoClinical FellowshipCardiology
    Columbia UniversityResearch Fellowship
    University of Texas SouthwesternInternship and ResidencyInternal Medicine
    University of Texas HoustonM.D.

    Collapse Overview 
    Collapse Overview
    Dr. Roland Wu is a cardiologist and physician-scientist specializing in general cardiology and echocardiography. His clinical interests include congestive heart failure and genetically-mediated cardiomyopathies, such as hypertrophic cardiomyopathy and dilated cardiomyopathies. His research is dedicated to the goal of leveraging basic scientific insights to develop clinically meaningful advances in cardiovascular medicine. His work focuses on using emerging technologies such as genetic screens, genetic engineering, high-throughput sequencing, and computational biology to understand cardiac regeneration, cardiac injury, and the transcriptional networks and signaling pathways that regulate these processes.

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Wu RS, Lam II, Clay H, Duong DN, Deo RC, Coughlin SR. A Rapid Method for Directed Gene Knockout for Screening in G0 Zebrafish. Dev Cell. 2018 07 02; 46(1):112-125.e4. PMID: 29974860.
      View in: PubMed
    2. Zhang Q, Huang H, Zhang L, Wu R, Chung CI, Zhang SQ, Torra J, Schepis A, Coughlin SR, Kornberg TB, Shu X. Visualizing Dynamics of Cell Signaling In Vivo with a Phase Separation-Based Kinase Reporter. Mol Cell. 2018 01 18; 69(2):347. PMID: 29351851.
      View in: PubMed
    3. Zhang Q, Huang H, Zhang L, Wu R, Chung CI, Zhang SQ, Torra J, Schepis A, Coughlin SR, Kornberg TB, Shu X. Visualizing Dynamics of Cell Signaling In Vivo with a Phase Separation-Based Kinase Reporter. Mol Cell. 2018 01 18; 69(2):334-346.e4. PMID: 29307513.
      View in: PubMed
    4. Zou J, Tran D, Baalbaki M, Tang LF, Poon A, Pelonero A, Titus EW, Yuan C, Shi C, Patchava S, Halper E, Garg J, Movsesyan I, Yin C, Wu R, Wilsbacher LD, Liu J, Hager RL, Coughlin SR, Jinek M, Pullinger CR, Kane JP, Hart DO, Kwok PY, Deo RC. An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish. Elife. 2015 Oct 16; 4:e09406. PMID: 26473617; PMCID: PMC4720518.
    5. Nilsen DW, Mehran R, Wu RS, Yu J, Nordrehaug JE, Brodie BR, Witzenbichler B, Nikolsky E, Fahy M, Stone GW. Coronary reperfusion and clinical outcomes after thrombus aspiration during primary percutaneous coronary intervention: findings from the HORIZONS-AMI trial. Catheter Cardiovasc Interv. 2013 Oct 01; 82(4):594-601. PMID: 23074151.
      View in: PubMed
    6. Niu X, Liu G, Wu RS, Chudasama N, Zakharov SI, Karlin A, Marx SO. Orientations and proximities of the extracellular ends of transmembrane helices S0 and S4 in open and closed BK potassium channels. PLoS One. 2013; 8(3):e58335. PMID: 23472181; PMCID: PMC3589268.
    7. Wu RS, Liu G, Zakharov SI, Chudasama N, Motoike H, Karlin A, Marx SO. Positions of ß2 and ß3 subunits in the large-conductance calcium- and voltage-activated BK potassium channel. J Gen Physiol. 2013 Jan; 141(1):105-17. PMID: 23277477; PMCID: PMC3536527.
    8. Wu RS, Marx SO. The BK potassium channel in the vascular smooth muscle and kidney: a- and ß-subunits. Kidney Int. 2010 Nov; 78(10):963-74. PMID: 20861815.
      View in: PubMed
    9. Liu G, Niu X, Wu RS, Chudasama N, Yao Y, Jin X, Weinberg R, Zakharov SI, Motoike H, Marx SO, Karlin A. Location of modulatory beta subunits in BK potassium channels. J Gen Physiol. 2010 May; 135(5):449-59. PMID: 20385746; PMCID: PMC2860586.
    10. Wu RS, Gupta S, Brown RN, Yancy CW, Wald JW, Kaiser P, Kirklin NM, Patel PC, Markham DW, Drazner MH, Garry DJ, Mammen PP. Clinical outcomes after cardiac transplantation in muscular dystrophy patients. J Heart Lung Transplant. 2010 Apr; 29(4):432-8. PMID: 19864165.
      View in: PubMed
    11. Wu RS, Chudasama N, Zakharov SI, Doshi D, Motoike H, Liu G, Yao Y, Niu X, Deng SX, Landry DW, Karlin A, Marx SO. Location of the beta 4 transmembrane helices in the BK potassium channel. J Neurosci. 2009 Jul 01; 29(26):8321-8. PMID: 19571123; PMCID: PMC2737688.
    12. Liu G, Zakharov SI, Yang L, Wu RS, Deng SX, Landry DW, Karlin A, Marx SO. Locations of the beta1 transmembrane helices in the BK potassium channel. Proc Natl Acad Sci U S A. 2008 Aug 05; 105(31):10727-32. PMID: 18669652; PMCID: PMC2504814.