Roland Wu, MD

Title(s)Assistant Clinical Professor, Medicine
SchoolSchool of Medicine
Address555 Mission Bay Blvd South, #382
San Francisco CA 94158
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    Collapse Biography 
    Collapse Education and Training
    University of California San FranciscoClinical FellowshipCardiology
    Columbia UniversityResearch Fellowship
    University of Texas SouthwesternInternship and ResidencyInternal Medicine
    University of Texas HoustonM.D.

    Collapse Overview 
    Collapse Overview
    I am a cardiologist and physician-scientist with board certifications in general cardiology and echocardiography. My clinical interest is in inpatient cardiology where I continue to practice.

    Since 2020, my primary appointment has been with Amgen where I focus on leveraging human genetics and basic scientific insights to create clinically meaningful advances in cardiovascular medicine. My research focuses on understanding human cardiovascular disease by studying the genetics and gene regulation underlying these disorders, utilizing technologies such as in vivo genetic and enhancer screens coupled with computational biology.

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Single Cell Multi-Omics of an iPSC Model of Human Sinoatrial Node Development Reveals Genetic Determinants of Heart Rate and Arrhythmia Susceptibility. bioRxiv. 2023 Sep 02. Engel JL, Zhang X, Lu DR, Vila OF, Arias V, Lee J, Hale C, Hsu YH, Li CM, Wu RS, Vedantham V, Ang YS. PMID: 37425707; PMCID: PMC10327193.
      View in: PubMed   Mentions:
    2. Cold shock domain-containing protein E1 is a posttranscriptional regulator of the LDL receptor. Sci Transl Med. 2022 09 14; 14(662):eabj8670. Smith GA, Padmanabhan A, Lau BH, Pampana A, Li L, Lee CY, Pelonero A, Nishino T, Sadagopan N, Xia VQ, Jain R, Natarajan P, Wu RS, Black BL, Srivastava D, Shokat KM, Chorba JS. PMID: 36103516; PMCID: PMC10174261.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    3. ATAC-Seq Reveals an Isl1 Enhancer That Regulates Sinoatrial Node Development and Function. Circ Res. 2020 12 04; 127(12):1502-1518. Galang G, Mandla R, Ruan H, Jung C, Sinha T, Stone NR, Wu RS, Mannion BJ, Allu PKR, Chang K, Rammohan A, Shi MB, Pennacchio LA, Black BL, Vedantham V. PMID: 33044128; PMCID: PMC7720845.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    4. A Rapid Method for Directed Gene Knockout for Screening in G0 Zebrafish. Dev Cell. 2018 07 02; 46(1):112-125.e4. Wu RS, Lam II, Clay H, Duong DN, Deo RC, Coughlin SR. PMID: 29974860.
      View in: PubMed   Mentions: 131     Fields:    Translation:AnimalsCells
    5. Visualizing Dynamics of Cell Signaling In Vivo with a Phase Separation-Based Kinase Reporter. Mol Cell. 2018 01 18; 69(2):347. Zhang Q, Huang H, Zhang L, Wu R, Chung CI, Zhang SQ, Torra J, Schepis A, Coughlin SR, Kornberg TB, Shu X. PMID: 29351851.
      View in: PubMed   Mentions: 11     Fields:    
    6. Visualizing Dynamics of Cell Signaling In Vivo with a Phase Separation-Based Kinase Reporter. Mol Cell. 2018 01 18; 69(2):334-346.e4. Zhang Q, Huang H, Zhang L, Wu R, Chung CI, Zhang SQ, Torra J, Schepis A, Coughlin SR, Kornberg TB, Shu X. PMID: 29307513; PMCID: PMC5788022.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    7. An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish. Elife. 2015 Oct 16; 4:e09406. Zou J, Tran D, Baalbaki M, Tang LF, Poon A, Pelonero A, Titus EW, Yuan C, Shi C, Patchava S, Halper E, Garg J, Movsesyan I, Yin C, Wu R, Wilsbacher LD, Liu J, Hager RL, Coughlin SR, Jinek M, Pullinger CR, Kane JP, Hart DO, Kwok PY, Deo RC. PMID: 26473617; PMCID: PMC4720518.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    8. Coronary reperfusion and clinical outcomes after thrombus aspiration during primary percutaneous coronary intervention: findings from the HORIZONS-AMI trial. Catheter Cardiovasc Interv. 2013 Oct 01; 82(4):594-601. Nilsen DW, Mehran R, Wu RS, Yu J, Nordrehaug JE, Brodie BR, Witzenbichler B, Nikolsky E, Fahy M, Stone GW. PMID: 23074151.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. Orientations and proximities of the extracellular ends of transmembrane helices S0 and S4 in open and closed BK potassium channels. PLoS One. 2013; 8(3):e58335. Niu X, Liu G, Wu RS, Chudasama N, Zakharov SI, Karlin A, Marx SO. PMID: 23472181; PMCID: PMC3589268.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    10. Positions of β2 and β3 subunits in the large-conductance calcium- and voltage-activated BK potassium channel. J Gen Physiol. 2013 Jan; 141(1):105-17. Wu RS, Liu G, Zakharov SI, Chudasama N, Motoike H, Karlin A, Marx SO. PMID: 23277477; PMCID: PMC3536527.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    11. The BK potassium channel in the vascular smooth muscle and kidney: α- and β-subunits. Kidney Int. 2010 Nov; 78(10):963-74. Wu RS, Marx SO. PMID: 20861815.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    12. Location of modulatory beta subunits in BK potassium channels. J Gen Physiol. 2010 May; 135(5):449-59. Liu G, Niu X, Wu RS, Chudasama N, Yao Y, Jin X, Weinberg R, Zakharov SI, Motoike H, Marx SO, Karlin A. PMID: 20385746; PMCID: PMC2860586.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    13. Clinical outcomes after cardiac transplantation in muscular dystrophy patients. J Heart Lung Transplant. 2010 Apr; 29(4):432-8. Wu RS, Gupta S, Brown RN, Yancy CW, Wald JW, Kaiser P, Kirklin NM, Patel PC, Markham DW, Drazner MH, Garry DJ, Mammen PP. PMID: 19864165.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    14. Location of the beta 4 transmembrane helices in the BK potassium channel. J Neurosci. 2009 Jul 01; 29(26):8321-8. Wu RS, Chudasama N, Zakharov SI, Doshi D, Motoike H, Liu G, Yao Y, Niu X, Deng SX, Landry DW, Karlin A, Marx SO. PMID: 19571123; PMCID: PMC2737688.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    15. Locations of the beta1 transmembrane helices in the BK potassium channel. Proc Natl Acad Sci U S A. 2008 Aug 05; 105(31):10727-32. Liu G, Zakharov SI, Yang L, Wu RS, Deng SX, Landry DW, Karlin A, Marx SO. PMID: 18669652; PMCID: PMC2504814.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
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