Ruth Huettenhain, PhD

TitleAssistant Professor
InstitutionUniversity of California San Francisco
DepartmentCellular Molecular Pharmacology
Address1700 4th St
San Francisco CA 94158
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    Collapse Biography 
    Collapse Education and Training
    Institute of Molecular Systems BiologyPostdoctoral Scholar2013ETH Zurich, Switzerland
    Institute of Molecular Systems BiologyPhD, Doctor of Sciences in Systems Biology2011ETH Zurich, Switzerland
    National Institute of Diabetes and Digestive and Kidney DiseasesDipl. Pharm. degree2006National Institute of Health, Bethesda, MD
    Institute of PharmacyPharmacy degree2005Friedrich-Wilhelms University of Bonn, Germany
    Collapse Awards and Honors
    Swiss National Science Foundation2015  - 2016Advanced Postdoc.Mobility Fellowship
    Human Frontiers Science Program (HFSP)2014  - 2018Long-Term Postdoctoral Fellowship
    European Molecular Biology Organization (EMBO)2014  - 2015Long-Term Postdoctoral Fellowship
    UCSF, San Francisco, CA2014  - 2015CFAR Basic Science Award in HIV/AIDS of the UCSF Resource Allocation Program (RAP)
    Swiss National Science Foundation2013  - 2014Early Postdoc.Mobility Fellowship
    ETH Zurich, Switzerland2013ETH medal for outstanding dissertation
    HUPO 2012, 11th World Congress, Boston, MA20122nd prize for young investigators in clinical proteomics
    HUPO 2011, 10th World Congress, Geneva2011Finalist for the EUPA Young Investigator Award in proteomics
    Swiss Proteomics Society Meeting 2009, Zurich, Switzerland2009Poster prize (Category: Biomarkers)
    EMBO Cancer Proteomics 2009, Dublin, Ireland2009Travel award
    Swiss Proteomics Society Meeting 2007, Lausanne, Switzerland 20071st Poster prize

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Sajic T, Liu Y, Arvaniti E, Surinova S, Williams EG, Schiess R, Hüttenhain R, Sethi A, Pan S, Brentnall TA, Chen R, Blattmann P, Friedrich B, Niméus E, Malander S, Omlin A, Gillessen S, Claassen M, Aebersold R. Similarities and Differences of Blood N-Glycoproteins in Five Solid Carcinomas at Localized Clinical Stage Analyzed by SWATH-MS. Cell Rep. 2018 May 29; 23(9):2819-2831.e5. PMID: 29847809.
      View in: PubMed
    2. Lobingier BT, Hüttenhain R, Eichel K, Miller KB, Ting AY, von Zastrow M, Krogan NJ. An Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells. Cell. 2017 Apr 06; 169(2):350-360.e12. PMID: 28388416.
      View in: PubMed
    3. Surinova S, Choi M, Tao S, Schüffler PJ, Chang CY, Clough T, Vysloužil K, Khoylou M, Srovnal J, Liu Y, Matondo M, Hüttenhain R, Weisser H, Buhmann JM, Hajdúch M, Brenner H, Vitek O, Aebersold R. Prediction of colorectal cancer diagnosis based on circulating plasma proteins. EMBO Mol Med. 2015 Sep; 7(9):1166-78. PMID: 26253081; PMCID: PMC4568950.
    4. Carr SA, Abbatiello SE, Ackermann BL, Borchers C, Domon B, Deutsch EW, Grant RP, Hoofnagle AN, Hüttenhain R, Koomen JM, Liebler DC, Liu T, MacLean B, Mani DR, Mansfield E, Neubert H, Paulovich AG, Reiter L, Vitek O, Aebersold R, Anderson L, Bethem R, Blonder J, Boja E, Botelho J, Boyne M, Bradshaw RA, Burlingame AL, Chan D, Keshishian H, Kuhn E, Kinsinger C, Lee JS, Lee SW, Moritz R, Oses-Prieto J, Rifai N, Ritchie J, Rodriguez H, Srinivas PR, Townsend RR, Van Eyk J, Whiteley G, Wiita A, Weintraub S. Targeted peptide measurements in biology and medicine: best practices for mass spectrometry-based assay development using a fit-for-purpose approach. Mol Cell Proteomics. 2014 Mar; 13(3):907-17. PMID: 24443746; PMCID: PMC3945918.
    5. Liu Y, Hüttenhain R, Collins B, Aebersold R. Mass spectrometric protein maps for biomarker discovery and clinical research. Expert Rev Mol Diagn. 2013 Nov; 13(8):811-25. PMID: 24138574; PMCID: PMC3833812.
    6. Surinova S, Hüttenhain R, Chang CY, Espona L, Vitek O, Aebersold R. Automated selected reaction monitoring data analysis workflow for large-scale targeted proteomic studies. Nat Protoc. 2013 Aug; 8(8):1602-19. PMID: 23887179.
      View in: PubMed
    7. Liu Y, Hüttenhain R, Surinova S, Gillet LC, Mouritsen J, Brunner R, Navarro P, Aebersold R. Quantitative measurements of N-linked glycoproteins in human plasma by SWATH-MS. Proteomics. 2013 Apr; 13(8):1247-56. PMID: 23322582.
      View in: PubMed
    8. Hüttenhain R, Surinova S, Ossola R, Sun Z, Campbell D, Cerciello F, Schiess R, Bausch-Fluck D, Rosenberger G, Chen J, Rinner O, Kusebauch U, Hajdúch M, Moritz RL, Wollscheid B, Aebersold R. N-glycoprotein SRMAtlas: a resource of mass spectrometric assays for N-glycosites enabling consistent and multiplexed protein quantification for clinical applications. Mol Cell Proteomics. 2013 Apr; 12(4):1005-16. PMID: 23408683; PMCID: PMC3617325.
    9. Hüttenhain R, Soste M, Selevsek N, Röst H, Sethi A, Carapito C, Farrah T, Deutsch EW, Kusebauch U, Moritz RL, Niméus-Malmström E, Rinner O, Aebersold R. Reproducible quantification of cancer-associated proteins in body fluids using targeted proteomics. Sci Transl Med. 2012 Jul 11; 4(142):142ra94. PMID: 22786679; PMCID: PMC3766734.
    10. Farrah T, Deutsch EW, Kreisberg R, Sun Z, Campbell DS, Mendoza L, Kusebauch U, Brusniak MY, Hüttenhain R, Schiess R, Selevsek N, Aebersold R, Moritz RL. PASSEL: the PeptideAtlas SRMexperiment library. Proteomics. 2012 Apr; 12(8):1170-5. PMID: 22318887; PMCID: PMC3832291.
    11. Ebhardt HA, Sabidó E, Hüttenhain R, Collins B, Aebersold R. Range of protein detection by selected/multiple reaction monitoring mass spectrometry in an unfractionated human cell culture lysate. Proteomics. 2012 Apr; 12(8):1185-93. PMID: 22577020.
      View in: PubMed
    12. Chang CY, Picotti P, Hüttenhain R, Heinzelmann-Schwarz V, Jovanovic M, Aebersold R, Vitek O. Protein significance analysis in selected reaction monitoring (SRM) measurements. Mol Cell Proteomics. 2012 Apr; 11(4):M111.014662. PMID: 22190732; PMCID: PMC3322573.
    13. Reiter L, Rinner O, Picotti P, Hüttenhain R, Beck M, Brusniak MY, Hengartner MO, Aebersold R. mProphet: automated data processing and statistical validation for large-scale SRM experiments. Nat Methods. 2011 May; 8(5):430-5. PMID: 21423193.
      View in: PubMed
    14. Surinova S, Schiess R, Hüttenhain R, Cerciello F, Wollscheid B, Aebersold R. On the development of plasma protein biomarkers. J Proteome Res. 2011 Jan 07; 10(1):5-16. PMID: 21142170.
      View in: PubMed
    15. Hüttenhain R, Hess S. A combined top-down and bottom-up MS approach for the characterization of hemoglobin variants in Rhesus monkeys. Proteomics. 2010 Oct; 10(20):3657-68. PMID: 20848672; PMCID: PMC3036950.
    16. Hüttenhain R, Malmström J, Picotti P, Aebersold R. Perspectives of targeted mass spectrometry for protein biomarker verification. Curr Opin Chem Biol. 2009 Dec; 13(5-6):518-25. PMID: 19818677; PMCID: PMC2795387.