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B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunity. Nature. 2021 Nov; 599(7885):471-476.
Zhang B, Vogelzang A, Miyajima M, Sugiura Y, Wu Y, Chamoto K, Nakano R, Hatae R, Menzies RJ, Sonomura K, Hojo N, Ogawa T, Kobayashi W, Tsutsui Y, Yamamoto S, Maruya M, Narushima S, Suzuki K, Sugiya H, Murakami K, Hashimoto M, Ueno H, Kobayashi T, Ito K, Hirano T, Shiroguchi K, Matsuda F, Suematsu M, Honjo T, Fagarasan S. PMID: 34732892; PMCID: PMC8599023.
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Intraventricular mucin-producing glioblastoma arising in the septum pellucidum at the frontal horn of the lateral ventricle: A case report. Neuropathology. 2021 Aug 12.
Takigawa K, Hata N, Sangatsuda Y, Suzuki SO, Sirozu N, Hatae R, Akagi Y, Iwaki T, Nagata S, Mizoguchi M. PMID: 34382251.
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PubMed Mentions: Fields:
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Novel EGFRvIII-CAR transgenic mice for rigorous preclinical studies in syngeneic mice. Neuro Oncol. 2021 Aug 04.
Chuntova P, Hou Y, Naka R, Yamamichi A, Chen T, Goretsky Y, Hatae R, Nejo T, Kohanbash G, Mende AL, Montoya M, Downey KM, Diebold D, Skinner J, Liang HE, Schwer B, Okada H. PMID: 34347086.
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Volumetric study reveals the relationship between outcome and early radiographic response during bevacizumab-containing chemoradiotherapy for unresectable glioblastoma. J Neurooncol. 2021 Sep; 154(2):187-196.
Takigawa K, Hata N, Michiwaki Y, Hiwatashi A, Yonezawa H, Kuga D, Hatae R, Sangatsuda Y, Fujioka Y, Funakoshi Y, Otsuji R, Sako A, Togao O, Yoshiura T, Yoshimoto K, Mizoguchi M. PMID: 34322829.
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PubMed Mentions:
1 Fields:
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Clinical implications of molecular analysis in diffuse glioma stratification. Brain Tumor Pathol. 2021 Jul; 38(3):210-217.
Mizoguchi M, Hata N, Kuga D, Hatae R, Akagi Y, Sangatsuda Y, Fujioka Y, Takigawa K, Funakoshi Y, Suzuki SO, Iwaki T. PMID: 34268651.
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CD206 Expression in Induced Microglia-Like Cells From Peripheral Blood as a Surrogate Biomarker for the Specific Immune Microenvironment of Neurosurgical Diseases Including Glioma. Front Immunol. 2021; 12:670131.
Tanaka S, Ohgidani M, Hata N, Inamine S, Sagata N, Shirouzu N, Mukae N, Suzuki SO, Hamasaki H, Hatae R, Sangatsuda Y, Fujioka Y, Takigawa K, Funakoshi Y, Iwaki T, Hosoi M, Iihara K, Mizoguchi M, Kato TA. PMID: 34267749.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Acute aortic dissection associated with wild-type transthyretin amyloid. Pathol Int. 2021 08; 71(8):556-558.
Mori S, Hatae R, Iwaki T. PMID: 34143916.
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Translation:
Humans
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Current trend in treatment of glioblastoma in Japan: a national survey using the diagnostic procedure combination database (J-ASPECT study-glioblastoma). Int J Clin Oncol. 2021 Aug; 26(8):1441-1449.
Funakoshi Y, Hata N, Kuga D, Hatae R, Sangatsuda Y, Fujioka Y, Takigawa K, Yoshimoto K, Mizoguchi M, Iihara K. PMID: 33974184.
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PubMed Mentions:
1 Fields:
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Clinical significance of CDKN2A homozygous deletion in combination with methylated MGMT status for IDH-wildtype glioblastoma. Cancer Med. 2021 05; 10(10):3177-3187.
Funakoshi Y, Hata N, Takigawa K, Arita H, Kuga D, Hatae R, Sangatsuda Y, Fujioka Y, Sako A, Umehara T, Yoshitake T, Togao O, Hiwatashi A, Yoshimoto K, Iwaki T, Mizoguchi M. PMID: 33838014.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Pediatric Glioma: An Update of Diagnosis, Biology, and Treatment. Cancers (Basel). 2021 Feb 12; 13(4).
Funakoshi Y, Hata N, Kuga D, Hatae R, Sangatsuda Y, Fujioka Y, Takigawa K, Mizoguchi M. PMID: 33673070.
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PubMed Mentions:
2
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Molecular diagnosis of diffuse glioma using a chip-based digital PCR system to analyze IDH, TERT, and H3 mutations in the cerebrospinal fluid. J Neurooncol. 2021 Mar; 152(1):47-54.
Fujioka Y, Hata N, Akagi Y, Kuga D, Hatae R, Sangatsuda Y, Michiwaki Y, Amemiya T, Takigawa K, Funakoshi Y, Sako A, Iwaki T, Iihara K, Mizoguchi M. PMID: 33417137.
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PubMed Mentions:
4 Fields:
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Mesenchymal glioblastoma-induced mature de-novo vessel formation of vascular endothelial cells in a microfluidic device. Mol Biol Rep. 2021 Jan; 48(1):395-403.
Amemiya T, Hata N, Mizoguchi M, Yokokawa R, Kawamura Y, Hatae R, Sangatsuda Y, Kuga D, Fujioka Y, Takigawa K, Akagi Y, Yoshimoto K, Iihara K, Miura T. PMID: 33387197.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Update on Chemotherapeutic Approaches and Management of Bevacizumab Usage for Glioblastoma. Pharmaceuticals (Basel). 2020 Dec 16; 13(12).
Funakoshi Y, Hata N, Kuga D, Hatae R, Sangatsuda Y, Fujioka Y, Takigawa K, Mizoguchi M. PMID: 33339404.
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3
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TERT promoter mutation confers favorable prognosis regardless of 1p/19q status in adult diffuse gliomas with IDH1/2 mutations. Acta Neuropathol Commun. 2020 11 23; 8(1):201.
Arita H, Matsushita Y, Machida R, Yamasaki K, Hata N, Ohno M, Yamaguchi S, Sasayama T, Tanaka S, Higuchi F, Iuchi T, Saito K, Kanamori M, Matsuda KI, Miyake Y, Tamura K, Tamai S, Nakamura T, Uda T, Okita Y, Fukai J, Sakamoto D, Hattori Y, Pareira ES, Hatae R, Ishi Y, Miyakita Y, Tanaka K, Takayanagi S, Otani R, Sakaida T, Kobayashi K, Saito R, Kurozumi K, Shofuda T, Nonaka M, Suzuki H, Shibuya M, Komori T, Sasaki H, Mizoguchi M, Kishima H, Nakada M, Sonoda Y, Tominaga T, Nagane M, Nishikawa R, Kanemura Y, Kuchiba A, Narita Y, Ichimura K. PMID: 33228806.
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PubMed Mentions:
4 Fields:
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Base-resolution methylomes of gliomas bearing histone H3.3 mutations reveal a G34 mutant-specific signature shared with bone tumors. Sci Rep. 2020 09 30; 10(1):16162.
Sangatsuda Y, Miura F, Araki H, Mizoguchi M, Hata N, Kuga D, Hatae R, Akagi Y, Amemiya T, Fujioka Y, Arai Y, Yoshida A, Shibata T, Yoshimoto K, Iihara K, Ito T. PMID: 32999376.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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First-line bevacizumab contributes to survival improvement in glioblastoma patients complementary to temozolomide. J Neurooncol. 2020 Feb; 146(3):451-458.
Hata N, Mizoguchi M, Kuga D, Hatae R, Akagi Y, Sangatsuda Y, Amemiya T, Michiwaki Y, Fujioka Y, Takigawa K, Suzuki SO, Yoshitake T, Togao O, Hiwatashi A, Yoshimoto K, Iihara K. PMID: 32020475.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Combination of host immune metabolic biomarkers for the PD-1 blockade cancer immunotherapy. JCI Insight. 2020 01 30; 5(2).
Hatae R, Chamoto K, Kim YH, Sonomura K, Taneishi K, Kawaguchi S, Yoshida H, Ozasa H, Sakamori Y, Akrami M, Fagarasan S, Masuda I, Okuno Y, Matsuda F, Hirai T, Honjo T. PMID: 31855576.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Current issues and perspectives in PD-1 blockade cancer immunotherapy. Int J Clin Oncol. 2020 May; 25(5):790-800.
Chamoto K, Hatae R, Honjo T. PMID: 31900651.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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A case of diffuse midline glioma, H3 K27M mutant mimicking a hemispheric malignant glioma in an elderly patient. Neuropathology. 2020 Feb; 40(1):99-103.
Fujioka Y, Hata N, Hatae R, Suzuki SO, Sangatsuda Y, Nakahara Y, Mizoguchi M, Iihara K. PMID: 31762138.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Relevance of calcification and contrast enhancement pattern for molecular diagnosis and survival prediction of gliomas based on the 2016 World Health Organization Classification. Clin Neurol Neurosurg. 2019 Dec; 187:105556.
Michiwaki Y, Hata N, Mizoguchi M, Hiwatashi A, Kuga D, Hatae R, Akagi Y, Amemiya T, Fujioka Y, Togao O, Suzuki SO, Yoshimoto K, Iwaki T, Iihara K. PMID: 31639630.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Analytical performance of a new automated chemiluminescent magnetic immunoassays for soluble PD-1, PD-L1, and CTLA-4 in human plasma. Sci Rep. 2019 07 12; 9(1):10144.
Goto M, Chamoto K, Higuchi K, Yamashita S, Noda K, Iino T, Miura M, Yamasaki T, Ogawa O, Sonobe M, Date H, Hamanishi J, Mandai M, Tanaka Y, Chikuma S, Hatae R, Muto M, Minamiguchi S, Minato N, Honjo T. PMID: 31300681; PMCID: PMC6626008.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Gliosarcoma arising from oligodendroglioma (Oligosarcoma): A case report with genetic analyses. Pathol Int. 2018 Oct; 68(10):567-573.
Tanaka S, Hitotsumatsu T, Sugita Y, Ishido K, Ito O, Hatae R, Akagi Y, Yoshimoto K, Iihara K. PMID: 30246385.
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PubMed Mentions: Fields:
Translation:
HumansCells
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An elderly case of malignant small cell glioma with hemorrhage coexistent with a calcified pilocytic astrocytoma component in the cerebellar hemisphere. Neuropathology. 2018 Oct; 38(5):493-497.
Sangatsuda Y, Hata N, Suzuki SO, Akagi Y, Hatae R, Kuga D, Yoshimoto K, Momosaki S, Iwaki T, Iihara K. PMID: 29851180.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Reclassification of 400 consecutive glioma cases based on the revised 2016WHO classification. Brain Tumor Pathol. 2018 Apr; 35(2):81-89.
Akagi Y, Yoshimoto K, Hata N, Kuga D, Hatae R, Amemiya T, Sangatsuda Y, Suzuki SO, Iwaki T, Mizoguchi M, Iihara K. PMID: 29569163.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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The Effectiveness of Salvage Treatments for Recurrent Lesions of Oligodendrogliomas Previously Treated with Upfront Chemotherapy. World Neurosurg. 2018 Jun; 114:e735-e742.
Kuga D, Hata N, Akagi Y, Amemiya T, Sangatsuda Y, Hatae R, Yoshimoto K, Mizoguchi M, Iihara K. PMID: 29551724.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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High-resolution melting and immunohistochemical analysis efficiently detects mutually exclusive genetic alterations of adamantinomatous and papillary craniopharyngiomas. Neuropathology. 2018 Feb; 38(1):3-10.
Yoshimoto K, Hatae R, Suzuki SO, Hata N, Kuga D, Akagi Y, Amemiya T, Sangatsuda Y, Mukae N, Mizoguchi M, Iwaki T, Iihara K. PMID: 28840946.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Prevalence and clinicopathological features of H3.3 G34-mutant high-grade gliomas: a retrospective study of 411 consecutive glioma cases in a single institution. Brain Tumor Pathol. 2017 Jul; 34(3):103-112.
Yoshimoto K, Hatae R, Sangatsuda Y, Suzuki SO, Hata N, Akagi Y, Kuga D, Hideki M, Yamashita K, Togao O, Hiwatashi A, Iwaki T, Mizoguchi M, Iihara K. PMID: 28447171.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Insular primary glioblastomas with IDH mutations: Clinical and biological specificities. Neuropathology. 2017 Jun; 37(3):200-206.
Hata N, Hatae R, Yoshimoto K, Murata H, Kuga D, Akagi Y, Sangatsuda Y, Suzuki SO, Iwaki T, Mizoguchi M, Iihara K. PMID: 28116838.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Add-on bevacizumab can prevent early clinical deterioration and prolong survival in newly diagnosed partially resected glioblastoma patients with a poor performance status. Onco Targets Ther. 2017; 10:429-437.
Hata N, Yoshimoto K, Hatae R, Kuga D, Akagi Y, Sangatsuda Y, Suzuki SO, Shono T, Mizoguchi M, Iihara K. PMID: 28176936.
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PubMed Mentions:
9
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Deferred radiotherapy and upfront procarbazine-ACNU-vincristine administration for 1p19q codeleted oligodendroglial tumors are associated with favorable outcome without compromising patient performance, regardless of WHO grade. Onco Targets Ther. 2016; 9:7123-7131.
Hata N, Yoshimoto K, Hatae R, Kuga D, Akagi Y, Suzuki SO, Iwaki T, Shono T, Mizoguchi M, Iihara K. PMID: 27895504.
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PubMed Mentions:
2
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[Rapid Progression in Early-Stage Primary Glioblastoma Multiforme:A Case Report]. No Shinkei Geka. 2016 Nov; 44(11):945-950.
Maehara N, Amano T, Haga S, Makihara K, Shimogawa T, Hatae R, Yoshimoto K, Suzuki S, Morioka T, Iihara K. PMID: 27832617.
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Humans
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A comprehensive analysis identifies BRAF hotspot mutations associated with gliomas with peculiar epithelial morphology. Neuropathology. 2017 Jun; 37(3):191-199.
Hatae R, Hata N, Suzuki SO, Yoshimoto K, Kuga D, Murata H, Akagi Y, Sangatsuda Y, Iwaki T, Mizoguchi M, Iihara K. PMID: 27792249.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Current Trends and Healthcare Resource Usage in the Hospital Treatment of Primary Malignant Brain Tumor in Japan: A National Survey Using the Diagnostic Procedure Combination Database (J-ASPECT Study-Brain Tumor). Neurol Med Chir (Tokyo). 2016 Nov 15; 56(11):664-673.
Yoshimoto K, Kada A, Kuga D, Hatae R, Murata H, Akagi Y, Nishimura K, Kurogi R, Nishimura A, Hata N, Mizoguchi M, Sayama T, Iihara K. PMID: 27680329.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Precise Detection of IDH1/2 and BRAF Hotspot Mutations in Clinical Glioma Tissues by a Differential Calculus Analysis of High-Resolution Melting Data. PLoS One. 2016; 11(8):e0160489.
Hatae R, Hata N, Yoshimoto K, Kuga D, Akagi Y, Murata H, Suzuki SO, Mizoguchi M, Iihara K, Hatae R, Hata N, Yoshimoto K, Kuga D, Akagi Y, Murata H, Suzuki SO, Mizoguchi M, Iihara K. PMID: 27529619; PMCID: PMC4987040.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas. Acta Neuropathol Commun. 2016 08 08; 4(1):79.
Arita H, Yamasaki K, Matsushita Y, Nakamura T, Shimokawa A, Takami H, Tanaka S, Mukasa A, Shirahata M, Shimizu S, Suzuki K, Saito K, Kobayashi K, Higuchi F, Uzuka T, Otani R, Tamura K, Sumita K, Ohno M, Miyakita Y, Kagawa N, Hashimoto N, Hatae R, Yoshimoto K, Shinojima N, Nakamura H, Kanemura Y, Okita Y, Kinoshita M, Ishibashi K, Shofuda T, Kodama Y, Mori K, Tomogane Y, Fukai J, Fujita K, Terakawa Y, Tsuyuguchi N, Moriuchi S, Nonaka M, Suzuki H, Shibuya M, Maehara T, Saito N, Nagane M, Kawahara N, Ueki K, Yoshimine T, Miyaoka E, Nishikawa R, Komori T, Narita Y, Ichimura K. PMID: 27503138; PMCID: PMC4977715.
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PubMed Mentions:
73 Fields:
Translation:
HumansCells
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Immune checkpoint inhibitors targeting programmed cell death-1 (PD-1) in cancer therapy. Rinsho Ketsueki. 2016; 57(10):2224-2231.
Hatae R, Chamoto K. PMID: 27795534.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Detection of proneural/mesenchymal marker expression in glioblastoma: temporospatial dynamics and association with chromatin-modifying gene expression. J Neurooncol. 2015 Oct; 125(1):33-41.
Murata H, Yoshimoto K, Hatae R, Akagi Y, Mizoguchi M, Hata N, Kuga D, Nakamizo A, Amano T, Sayama T, Iihara K, Murata H, Yoshimoto K, Hatae R, Akagi Y, Mizoguchi M, Hata N, Kuga D, Nakamizo A, Amano T, Sayama T, Iihara K. PMID: 26272600.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Genetic analysis of a case of glioblastoma with oligodendroglial component arising during the progression of diffuse astrocytoma. Pathol Oncol Res. 2015 Jul; 21(3):839-43.
Hata N, Suzuki SO, Murata H, Hatae R, Akagi Y, Sangatsuda Y, Amano T, Yoshimoto K, Tahira T, Mizoguchi M, Hata N, Suzuki SO, Murata H, Hatae R, Akagi Y, Sangatsuda Y, Amano T, Yoshimoto K, Tahira T, Mizoguchi M. PMID: 25354913.
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Translation:
Humans
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Trochlear nerve schwannoma with intratumoral hemorrhage presenting with persistent hiccups: a case report. J Neurol Surg Rep. 2014 Aug; 75(1):e183-8.
Hatae R, Miyazono M, Kohri R, Maeda K, Naito S, Hatae R, Miyazono M, Kohri R, Maeda K, Naito S. PMID: 25083382; PMCID: PMC4110147.
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PubMed Mentions:
2
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[Two cases of anterior cerebral artery aneurysm associated with accessory anterior cerebral artery: review of the literature and points of diagnosis]. No Shinkei Geka. 2014 May; 42(5):461-6.
Maeda K, Tanaka S, Hatae R, Maeda Y, Miyazono M, Maeda K, Tanaka S, Hatae R, Maeda Y, Miyazono M. PMID: 24807551.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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A rare case of Chiari type-1 malformation accompanied by symptomatic cerebrospinal fluid hypovolemia: comparison of congenital Chiari type-1 malformation and acquired Chiari malformation secondary to cerebrospinal fluid hypovolemia: case report. Neurol Med Chir (Tokyo). 2014; 54(7):558-62.
Hatae R, Kohri R, Maeda K, Miyazono M, Hatae R, Kohri R, Maeda K, Miyazono M. PMID: 24477061; PMCID: PMC4533466.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Complex DNA repair pathways as possible therapeutic targets to overcome temozolomide resistance in glioblastoma. Front Oncol. 2012; 2:186.
Yoshimoto K, Mizoguchi M, Hata N, Murata H, Hatae R, Amano T, Nakamizo A, Sasaki T, Yoshimoto K, Mizoguchi M, Hata N, Murata H, Hatae R, Amano T, Nakamizo A, Sasaki T. PMID: 23227453; PMCID: PMC3514620.
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PubMed Mentions:
37
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[A case of internal carotid artery stenosis with discontinuance of carotid endarterectomy due to the tight adhesions around the internal carotid artery]. No Shinkei Geka. 2012 May; 40(5):445-50.
Kohri R, Miyazono M, Hatae R, Maeda K, Takahira A, Maeda Y, Mizota T, Naito S, Kohri R, Miyazono M, Hatae R, Maeda K, Takahira A, Maeda Y, Mizota T, Naito S. PMID: 22538287.
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PubMed Mentions: Fields:
Translation:
Humans