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Sabrina Ronen, PhD

Title(s)Professor, Radiology
SchoolSchool of Medicine
Address1700 4th St
San Francisco CA 94158
Phone415-514-4839
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    Collapse Biography 
    Collapse Awards and Honors
    International Society of Magnetic Resonance in Medicine (ISMRM)2016Nominated Senior Fellow
    World Molecular Imaging Society2015  - 2018Board of Trustees
    Academy of Radiology Research2013Distinguished Investigator
    International Society of Magnetic Resonance in Medicine (ISMRM)2008  - 2011Annual Meeting Program Committee (AMPC)
    CRUK Institute of Cancer Research1996ICR Fellowship
    Israel Ministry of Science1987Eshkol Scholarship

    Collapse Overview 
    Collapse Overview
    Sabrina M. Ronen, PhD, is a Professor and Director of the Neuroimaging Research Group in the UCSF Department of Radiology and Biomedical Imaging. Dr. Ronen completed her BS in Chemistry and Biochemistry at the Hebrew University in Jerusalem, Israel, received her MS in Chemistry from San Jose State University, and obtained her PhD in Chemical Physics from The Weizmann Institute of Science in Rehovot, Israel. She then trained as a postdoctoral fellow at the Institut Curie in Paris, France, and started her academic career at the Institute of Cancer Research in London, England.

    Dr. Ronen’s Laboratory focuses on developing and mechanistically validating robust non-invasive translatable magnetic resonance (MR)–based biomarkers that can be used to monitor oncogenic transformation and response to therapy. Dr. Ronen has ongoing research projects on monitoring PI3K signaling, detecting the mutational status of isocitrate dehydrogenase, probing the metabolism of brain tumors, and determining the metabolomic profile of pancreatic cancer.

    Expertise:
    Magnetic resonance spectroscopy (MRS), spectroscopic imaging (MRSI), imaging (MRI), metabolism, cancer, bioengineering

    Specialty:
    Preclinical cancer models

    Professional Interests:
    Magnetic resonance, spectroscopy, imaging, cancer, metabolism, cell signaling, biomarkers

    Education and Training:
    • Bachelor of Science: Hebrew University, Jerusalem, Israel - Cum Laude, Chemistry and Biochemistry
    • Masters of Science: San Jose State University, San Jose - Chemistry
    • Doctor of Philosophy: Weizmann Institute of Science, Rehovot, Israel - Chemical Physics
    • Postdoctoral Fellowship: Institut Curie, Paris, France - Imaging
    • Postdoctoral Fellowship: Harefield Hospital, London, England - Imaging

    Collapse Research 
    Collapse Research Activities and Funding
    IMAGING TELOMERE MAINTENANCE MECHANISMS IN GLIOMAS
    NIH/NCI R01CA239288Feb 11, 2020 - Jan 31, 2025
    Role: Co-Principal Investigator
    Metabolic Imaging of Brain Tumor Response to Therapy
    NIH/NCI R01CA197254Apr 1, 2016 - Mar 31, 2021
    Role: Principal Investigator
    Hyperpolarized arginine imaging of inflammatory cells and their inhibition in GBM
    NIH/NCI R21CA201453Dec 1, 2015 - Nov 30, 2017
    Role: Principal Investigator
    Metabolic Reprogramming in Brain Tumors
    NIH/NCI R01CA172845Feb 5, 2013 - Jan 31, 2018
    Role: Principal Investigator
    MR Imaging of IDH Mutational Status in Brain Tumors
    NIH/NCI R21CA161545Apr 2, 2012 - Mar 31, 2014
    Role: Principal Investigator
    MR Metabolic Imaging of Response to Targeted Therapies in GBM
    NIH/NCI R01CA154915Sep 8, 2011 - Jun 30, 2016
    Role: Principal Investigator
    Phosphocholine modulation by oncognenic signaling - MRS studies of mechanism
    NIH/NCI R01CA130819Sep 3, 2008 - Jul 31, 2013
    Role: Principal Investigator
    Non-invasive molecular MR spectroscopic imaging of histone deacetylase activity
    NIH/NCI R21CA120010Jun 18, 2007 - May 31, 2010
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. MR-detectable metabolic biomarkers of response to mutant IDH inhibition in low-grade glioma. Theranostics. 2020; 10(19):8757-8770. Molloy AR, Najac C, Viswanath P, Lakhani A, Subramani E, Batsios G, Radoul M, Gillespie AM, Pieper RO, Ronen SM. PMID: 32754276.
      View in: PubMed   Mentions:    Fields:    
    2. In vivo detection of ?-glutamyl-transferase up-regulation in glioma using hyperpolarized ?-glutamyl-[1-13C]glycine. Sci Rep. 2020 Apr 10; 10(1):6244. Batsios G, Najac C, Cao P, Viswanath P, Subramani E, Saito Y, Gillespie AM, Yoshihara HAI, Larson P, Sando S, Ronen SM. PMID: 32277103.
      View in: PubMed   Mentions:    Fields:    
    3. First hyperpolarized [2-13C]pyruvate MR studies of human brain metabolism. J Magn Reson. 2019 12; 309:106617. Chung BT, Chen HY, Gordon J, Mammoli D, Sriram R, Autry AW, Le Page LM, Chaumeil MM, Shin P, Slater J, Tan CT, Suszczynski C, Chang S, Li Y, Bok RA, Ronen SM, Larson PEZ, Kurhanewicz J, Vigneron DB. PMID: 31648132.
      View in: PubMed   Mentions: 4     Fields:    
    4. PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival. Sci Rep. 2019 07 19; 9(1):10521. Batsios G, Viswanath P, Subramani E, Najac C, Gillespie AM, Santos RD, Molloy AR, Pieper RO, Ronen SM. PMID: 31324855.
      View in: PubMed   Mentions: 2     Fields:    
    5. In vivo investigation of hyperpolarized [1,3-13C2]acetoacetate as a metabolic probe in normal brain and in glioma. Sci Rep. 2019 03 04; 9(1):3402. Najac C, Radoul M, Le Page LM, Batsios G, Subramani E, Viswanath P, Gillespie AM, Ronen SM. PMID: 30833594.
      View in: PubMed   Mentions: 2     Fields:    
    6. HDAC inhibition in glioblastoma monitored by hyperpolarized 13 C MRSI. NMR Biomed. 2019 02; 32(2):e4044. Radoul M, Najac C, Viswanath P, Mukherjee J, Kelly M, Gillespie AM, Chaumeil MM, Eriksson P, Delos Santos R, Pieper RO, Ronen SM. PMID: 30561869.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    7. Hyperpolarized 13C MRI: Path to Clinical Translation in Oncology. Neoplasia. 2019 01; 21(1):1-16. Kurhanewicz J, Vigneron DB, Ardenkjaer-Larsen JH, Bankson JA, Brindle K, Cunningham CH, Gallagher FA, Keshari KR, Kjaer A, Laustsen C, Mankoff DA, Merritt ME, Nelson SJ, Pauly JM, Lee P, Ronen S, Tyler DJ, Rajan SS, Spielman DM, Wald L, Zhang X, Malloy CR, Rizi R. PMID: 30472500.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    8. Late-stage deuteration of 13C-enriched substrates for T1 prolongation in hyperpolarized 13C MRI. Chem Commun (Camb). 2018 May 17; 54(41):5233-5236. Taglang C, Korenchan DE, von Morze C, Yu J, Najac C, Wang S, Blecha JE, Subramaniam S, Bok R, VanBrocklin HF, Vigneron DB, Ronen SM, Sriram R, Kurhanewicz J, Wilson DM, Flavell RR. PMID: 29726563.
      View in: PubMed   Mentions: 1     Fields:    
    9. Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner. Cancer Metab. 2018; 6:3. Viswanath P, Radoul M, Izquierdo-Garcia JL, Luchman HA, Gregory Cairncross J, Pieper RO, Phillips JJ, Ronen SM. PMID: 29619216.
      View in: PubMed   Mentions:
    10. 2-Hydroxyglutarate-Mediated Autophagy of the Endoplasmic Reticulum Leads to an Unusual Downregulation of Phospholipid Biosynthesis in Mutant IDH1 Gliomas. Cancer Res. 2018 05 01; 78(9):2290-2304. Viswanath P, Radoul M, Izquierdo-Garcia JL, Ong WQ, Luchman HA, Cairncross JG, Huang B, Pieper RO, Phillips JJ, Ronen SM. PMID: 29358170.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    11. Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant IDH1. Proc Natl Acad Sci U S A. 2017 10 03; 114(40):10743-10748. Mazor T, Chesnelong C, Pankov A, Jalbert LE, Hong C, Hayes J, Smirnov IV, Marshall R, Souza CF, Shen Y, Viswanath P, Noushmehr H, Ronen SM, Jones SJM, Marra MA, Cairncross JG, Perry A, Nelson SJ, Chang SM, Bollen AW, Molinaro AM, Bengtsson H, Olshen AB, Weiss S, Phillips JJ, Luchman HA, Costello JF. PMID: 28916733.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    12. Hyperpolarized 13C MR metabolic imaging can detect neuroinflammation in vivo in a multiple sclerosis murine model. Proc Natl Acad Sci U S A. 2017 08 15; 114(33):E6982-E6991. Guglielmetti C, Najac C, Didonna A, Van der Linden A, Ronen SM, Chaumeil MM. PMID: 28760957.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    13. Autophagy-Dependent Shuttling of TBC1D5 Controls Plasma Membrane Translocation of GLUT1 and Glucose Uptake. Mol Cell. 2017 Jul 06; 67(1):84-95.e5. Roy S, Leidal AM, Ye J, Ronen SM, Debnath J. PMID: 28602638.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    14. Metabolic Profiling of IDH Mutation and Malignant Progression in Infiltrating Glioma. Sci Rep. 2017 03 22; 7:44792. Jalbert LE, Elkhaled A, Phillips JJ, Neill E, Williams A, Crane JC, Olson MP, Molinaro AM, Berger MS, Kurhanewicz J, Ronen SM, Chang SM, Nelson SJ. PMID: 28327577.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    15. GLUT3 upregulation promotes metabolic reprogramming associated with antiangiogenic therapy resistance. JCI Insight. 2017 01 26; 2(2):e88815. Kuang R, Jahangiri A, Mascharak S, Nguyen A, Chandra A, Flanigan PM, Yagnik G, Wagner JR, De Lay M, Carrera D, Castro BA, Hayes J, Sidorov M, Garcia JLI, Eriksson P, Ronen S, Phillips J, Molinaro A, Koliwad S, Aghi MK. PMID: 28138554.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    16. Mutant IDH1 Expression Drives TERT Promoter Reactivation as Part of the Cellular Transformation Process. Cancer Res. 2016 11 15; 76(22):6680-6689. Ohba S, Mukherjee J, Johannessen TC, Mancini A, Chow TT, Wood M, Jones L, Mazor T, Marshall RE, Viswanath P, Walsh KM, Perry A, Bell RJ, Phillips JJ, Costello JF, Ronen SM, Pieper RO. PMID: 27758882.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    17. MR Molecular Imaging of Brain Cancer Metabolism Using Hyperpolarized 13C Magnetic Resonance Spectroscopy. Top Magn Reson Imaging. 2016 Oct; 25(5):187-196. Najac C, Ronen SM. PMID: 27748711.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    18. Detection of inflammatory cell function using (13)C magnetic resonance spectroscopy of hyperpolarized [6-(13)C]-arginine. Sci Rep. 2016 08 10; 6:31397. Najac C, Chaumeil MM, Kohanbash G, Guglielmetti C, Gordon JW, Okada H, Ronen SM. PMID: 27507680.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    19. Rapid Conversion of Mutant IDH1 from Driver to Passenger in a Model of Human Gliomagenesis. Mol Cancer Res. 2016 10; 14(10):976-983. Johannessen TA, Mukherjee J, Viswanath P, Ohba S, Ronen SM, Bjerkvig R, Pieper RO. PMID: 27430238.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    20. Hyperpolarized (13)C MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring. Neuroimage Clin. 2016; 12:180-9. Chaumeil MM, Radoul M, Najac C, Eriksson P, Viswanath P, Blough MD, Chesnelong C, Luchman HA, Cairncross JG, Ronen SM. PMID: 27437179.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    21. Mutant IDH1 expression is associated with down-regulation of monocarboxylate transporters. Oncotarget. 2016 Jun 07; 7(23):34942-55. Viswanath P, Najac C, Izquierdo-Garcia JL, Pankov A, Hong C, Eriksson P, Costello JF, Pieper RO, Ronen SM. PMID: 27144334.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    22. Imaging Renal Urea Handling in Rats at Millimeter Resolution using Hyperpolarized Magnetic Resonance Relaxometry. Tomography. 2016 Jun; 2(2):125-135. Reed GD, von Morze C, Verkman AS, Koelsch BL, Chaumeil MM, Lustig M, Ronen SM, Bok RA, Sands JM, Larson PE, Wang ZJ, Larsen JH, Kurhanewicz J, Vigneron DB. PMID: 27570835.
      View in: PubMed   Mentions: 7     Fields:    
    23. Accelerated high-bandwidth MR spectroscopic imaging using compressed sensing. Magn Reson Med. 2016 08; 76(2):369-79. Cao P, Shin PJ, Park I, Najac C, Marco-Rius I, Vigneron DB, Nelson SJ, Ronen SM, Larson PE. PMID: 27228088.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    24. Molecular Imaging of Metabolic Reprograming in Mutant IDH Cells. Front Oncol. 2016; 6:60. Viswanath P, Chaumeil MM, Ronen SM. PMID: 27014635.
      View in: PubMed   Mentions:
    25. MR Studies of Glioblastoma Models Treated with Dual PI3K/mTOR Inhibitor and Temozolomide:Metabolic Changes Are Associated with Enhanced Survival. Mol Cancer Ther. 2016 05; 15(5):1113-22. Radoul M, Chaumeil MM, Eriksson P, Wang AS, Phillips JJ, Ronen SM. PMID: 26883274.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    26. 1 H-13 C independently tuned radiofrequency surface coil applied for in vivo hyperpolarized MRI. Magn Reson Med. 2016 11; 76(5):1612-1620. Cao P, Zhang X, Park I, Najac C, Nelson SJ, Ronen S, Larson PE. PMID: 26597845.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    27. Magnetic Resonance (MR) Metabolic Imaging in Glioma. Brain Pathol. 2015 Nov; 25(6):769-80. Chaumeil MM, Lupo JM, Ronen SM. PMID: 26526945.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    28. Metabolic reprogramming of pyruvate dehydrogenase is essential for the proliferation of glioma cells expressing mutant IDH1. Mol Cell Oncol. 2016 Apr 01; 3(2):e1077922. Viswanath P, Ronen SM. PMID: 26985452.
      View in: PubMed   Mentions:
    29. Studies of Metabolism Using (13)C MRS of Hyperpolarized Probes. Methods Enzymol. 2015; 561:1-71. Chaumeil MM, Najac C, Ronen SM. PMID: 26358901.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    30. IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism. Cancer Res. 2015 Aug 01; 75(15):2999-3009. Izquierdo-Garcia JL, Viswanath P, Eriksson P, Cai L, Radoul M, Chaumeil MM, Blough M, Luchman HA, Weiss S, Cairncross JG, Phillips JJ, Pieper RO, Ronen SM. PMID: 26045167.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    31. Metabolic reprogramming in mutant IDH1 glioma cells. PLoS One. 2015; 10(2):e0118781. Izquierdo-Garcia JL, Viswanath P, Eriksson P, Chaumeil MM, Pieper RO, Phillips JJ, Ronen SM. PMID: 25706986.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    32. Changes in pyruvate metabolism detected by magnetic resonance imaging are linked to DNA damage and serve as a sensor of temozolomide response in glioblastoma cells. Cancer Res. 2014 Dec 01; 74(23):7115-24. Park I, Mukherjee J, Ito M, Chaumeil MM, Jalbert LE, Gaensler K, Ronen SM, Nelson SJ, Pieper RO. PMID: 25320009.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    33. Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase. PLoS One. 2014; 9(9):e108289. Izquierdo-Garcia JL, Cai LM, Chaumeil MM, Eriksson P, Robinson AE, Pieper RO, Phillips JJ, Ronen SM. PMID: 25243911.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    34. Rapid in vivo apparent diffusion coefficient mapping of hyperpolarized (13) C metabolites. Magn Reson Med. 2015 Sep; 74(3):622-633. Koelsch BL, Reed GD, Keshari KR, Chaumeil MM, Bok R, Ronen SM, Vigneron DB, Kurhanewicz J, Larson PEZ. PMID: 25213126.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    35. HR-MAS MRS of the pancreas reveals reduced lipid and elevated lactate and taurine associated with early pancreatic cancer. NMR Biomed. 2014 Nov; 27(11):1361-70. Wang AS, Lodi A, Rivera LB, Izquierdo-Garcia JL, Firpo MA, Mulvihill SJ, Tempero MA, Bergers G, Ronen SM. PMID: 25199993.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    36. Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma. Cancer Res. 2014 Aug 15; 74(16):4247-57. Chaumeil MM, Larson PE, Woods SM, Cai L, Eriksson P, Robinson AE, Lupo JM, Vigneron DB, Nelson SJ, Pieper RO, Phillips JJ, Ronen SM. PMID: 24876103.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    37. Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer. Cell. 2014 May 22; 157(5):1088-103. Cunningham JT, Moreno MV, Lodi A, Ronen SM, Ruggero D. PMID: 24855946.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    38. MR-detectable metabolic consequences of mitogen-activated protein kinase kinase (MEK) inhibition. NMR Biomed. 2014 Jun; 27(6):700-8. Lodi A, Woods SM, Ronen SM. PMID: 24706368.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    39. Lactate dehydrogenase A silencing in IDH mutant gliomas. Neuro Oncol. 2014 May; 16(5):686-95. Chesnelong C, Chaumeil MM, Blough MD, Al-Najjar M, Stechishin OD, Chan JA, Pieper RO, Ronen SM, Weiss S, Luchman HA, Cairncross JG. PMID: 24366912.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    40. Early Chk1 phosphorylation is driven by temozolomide-induced, DNA double strand break- and mismatch repair-independent DNA damage. PLoS One. 2013; 8(5):e62351. Ito M, Ohba S, Gaensler K, Ronen SM, Mukherjee J, Pieper RO. PMID: 23667469.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    41. HDAC inhibition induces increased choline uptake and elevated phosphocholine levels in MCF7 breast cancer cells. PLoS One. 2013; 8(4):e62610. Ward CS, Eriksson P, Izquierdo-Garcia JL, Brandes AH, Ronen SM. PMID: 23626839.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    42. Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma. PLoS One. 2013; 8(2):e57610. Mukherjee J, Phillips JJ, Zheng S, Wiencke J, Ronen SM, Pieper RO. PMID: 23451252.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    43. Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance. Clin Cancer Res. 2013 Apr 01; 19(7):1773-83. Jahangiri A, De Lay M, Miller LM, Carbonell WS, Hu YL, Lu K, Tom MW, Paquette J, Tokuyasu TA, Tsao S, Marshall R, Perry A, Bjorgan KM, Chaumeil MM, Ronen SM, Bergers G, Aghi MK. PMID: 23307858.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    44. Non-invasive in vivo assessment of IDH1 mutational status in glioma. Nat Commun. 2013; 4:2429. Chaumeil MM, Larson PE, Yoshihara HA, Danforth OM, Vigneron DB, Nelson SJ, Pieper RO, Phillips JJ, Ronen SM. PMID: 24019001.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    45. Treatment with the MEK inhibitor U0126 induces decreased hyperpolarized pyruvate to lactate conversion in breast, but not prostate, cancer cells. NMR Biomed. 2013 Mar; 26(3):299-306. Lodi A, Woods SM, Ronen SM. PMID: 22945392.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    46. Evaluation of heterogeneous metabolic profile in an orthotopic human glioblastoma xenograft model using compressed sensing hyperpolarized 3D 13C magnetic resonance spectroscopic imaging. Magn Reson Med. 2013 Jul; 70(1):33-9. Park I, Hu S, Bok R, Ozawa T, Ito M, Mukherjee J, Phillips JJ, James CD, Pieper RO, Ronen SM, Vigneron DB, Nelson SJ. PMID: 22851374.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    47. Longitudinal evaluation of MPIO-labeled stem cell biodistribution in glioblastoma using high resolution and contrast-enhanced MR imaging at 14.1 tesla. Neuro Oncol. 2012 Aug; 14(8):1050-61. Chaumeil MM, Gini B, Yang H, Iwanami A, Sukumar S, Ozawa T, Pieper RO, Mischel PS, James CD, Berger MS, Ronen SM. PMID: 22670012.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    48. Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma. Neuro Oncol. 2012 Mar; 14(3):315-25. Venkatesh HS, Chaumeil MM, Ward CS, Haas-Kogan DA, James CD, Ronen SM. PMID: 22156546.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    49. Vascular patterning and permeability in prostate cancer models with differing osteogenic properties. NMR Biomed. 2012 Jun; 25(6):843-51. Dafni H, Burghardt AJ, Majumdar S, Navone NM, Ronen SM. PMID: 22134886.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    50. Choline metabolism in malignant transformation. Nat Rev Cancer. 2011 Nov 17; 11(12):835-48. Glunde K, Bhujwalla ZM, Ronen SM. PMID: 22089420.
      View in: PubMed   Mentions: 209     Fields:    Translation:HumansAnimalsCells
    51. Magnetic resonance spectroscopy detectable metabolomic fingerprint of response to antineoplastic treatment. PLoS One. 2011; 6(10):e26155. Lodi A, Ronen SM. PMID: 22022547.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    52. Metabolic consequences of treatment with AKT inhibitor perifosine in breast cancer cells. NMR Biomed. 2012 Feb; 25(2):379-88. Su JS, Woods SM, Ronen SM. PMID: 22253088.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    53. Hyperpolarized 13C MR spectroscopic imaging can be used to monitor Everolimus treatment in vivo in an orthotopic rodent model of glioblastoma. Neuroimage. 2012 Jan 02; 59(1):193-201. Chaumeil MM, Ozawa T, Park I, Scott K, James CD, Nelson SJ, Ronen SM. PMID: 21807103.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimals
    54. Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging. J Magn Reson Imaging. 2011 Jun; 33(6):1284-90. Park I, Bok R, Ozawa T, Phillips JJ, James CD, Vigneron DB, Ronen SM, Nelson SJ. PMID: 21590996.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    55. Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation. Mol Biol Cell. 2011 Jan 15; 22(2):165-78. Lock R, Roy S, Kenific CM, Su JS, Salas E, Ronen SM, Debnath J. PMID: 21119005.
      View in: PubMed   Mentions: 172     Fields:    Translation:HumansAnimalsCells
    56. 17-allyamino-17-demethoxygeldanamycin treatment results in a magnetic resonance spectroscopy-detectable elevation in choline-containing metabolites associated with increased expression of choline transporter SLC44A1 and phospholipase A2. Breast Cancer Res. 2010; 12(5):R84. Brandes AH, Ward CS, Ronen SM. PMID: 20946630.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    57. Hyperpolarized 13C spectroscopic imaging informs on hypoxia-inducible factor-1 and myc activity downstream of platelet-derived growth factor receptor. Cancer Res. 2010 Oct 01; 70(19):7400-10. Dafni H, Larson PE, Hu S, Yoshihara HA, Ward CS, Venkatesh HS, Wang C, Zhang X, Vigneron DB, Ronen SM. PMID: 20858719.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    58. Cellular and in vivo activity of a novel PI3K inhibitor, PX-866, against human glioblastoma. Neuro Oncol. 2010 Jun; 12(6):559-69. Koul D, Shen R, Kim YW, Kondo Y, Lu Y, Bankson J, Ronen SM, Kirkpatrick DL, Powis G, Yung WK. PMID: 20156803.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    59. Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy. Cancer Res. 2010 Feb 15; 70(4):1296-305. Ward CS, Venkatesh HS, Chaumeil MM, Brandes AH, Vancriekinge M, Dafni H, Sukumar S, Nelson SJ, Vigneron DB, Kurhanewicz J, James CD, Haas-Kogan DA, Ronen SM. PMID: 20145128.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    60. Dynamic nuclear polarization in metabolic imaging of metastasis: common sense, hypersense and compressed sensing. Cancer Biomark. 2010; 7(4):189-99. Dafni H, Ronen SM. PMID: 21576812.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    61. Macromolecular dynamic contrast-enhanced (DCE)-MRI detects reduced vascular permeability in a prostate cancer bone metastasis model following anti-platelet-derived growth factor receptor (PDGFR) therapy, indicating a drop in vascular endothelial growth factor receptor (VEGFR) activation. Magn Reson Med. 2008 Oct; 60(4):822-33. Dafni H, Kim SJ, Bankson JA, Sankaranarayanapillai M, Ronen SM. PMID: 18816866.
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