Sandeep Kunwar, MD
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Title(s) | Associate Professor, Neurological Surgery |
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School | School of Medicine |
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vCard | Download vCard |
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Title(s) | UCSF Weill Institute for Neurosciences |
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Bibliographic
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López GY, Van Ziffle J, Onodera C, Grenert JP, Yeh I, Bastian BC, Clarke J, Oberheim Bush NA, Taylor J, Chang S, Butowski N, Banerjee A, Mueller S, Kline C, Torkildson J, Samuel D, Siongco A, Raffel C, Gupta N, Kunwar S, Mummaneni P, Aghi M, Theodosopoulos P, Berger M, Phillips JJ, Pekmezci M, Tihan T, Bollen AW, Perry A, Solomon DA. The genetic landscape of gliomas arising after therapeutic radiation. Acta Neuropathol. 2019 Jan; 137(1):139-150. PMID: 30196423.
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Rick J, Jahangiri A, Flanigan PM, Chandra A, Kunwar S, Blevins L, Aghi MK. Growth hormone and prolactin-staining tumors causing acromegaly: a retrospective review of clinical presentations and surgical outcomes. J Neurosurg. 2018 Sep 01; 1-7. PMID: 30215558.
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Kunwar S, Parekh JD, Chilukuri RS, Andukuri VA. Necrotizing Autoimmune myopathy: A case report on statin induced rhabdomyolysis requiring immunosuppressive therapy. Drug Discov Ther. 2018; 12(5):315-317. PMID: 30464165.
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Rutkowski MJ, Kunwar S, Blevins L, Aghi MK. Surgical intervention for pituitary apoplexy: an analysis of functional outcomes. J Neurosurg. 2018 08; 129(2):417-424. PMID: 28946177.
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Jahangiri A, Chin AT, Wagner JR, Kunwar S, Ames C, Chou D, Barani I, Parsa AT, McDermott MW, Benet A, El-Sayed IH, Aghi MK. In Reply: Factors Predicting Recurrence After Resection of Clival Chordoma Using Variable Surgical Approaches and Radiation Modalities. Neurosurgery. 2017 08 01; 81(2):E32. PMID: 28379552.
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Rutkowski MJ, Alward RM, Chen R, Wagner J, Jahangiri A, Southwell DG, Kunwar S, Blevins L, Lee H, Aghi MK. Atypical pituitary adenoma: a clinicopathologic case series. J Neurosurg. 2018 04; 128(4):1058-1065. PMID: 28598278.
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Coe JD, Zucherman JF, Kucharzyk DW, Poelstra KA, Miller LE, Kunwar S. Multiexpandable cage for minimally invasive posterior lumbar interbody fusion. Med Devices (Auckl). 2016; 9:341-347. PMID: 27729817.
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Imber BS, Lee HS, Kunwar S, Blevins LS, Aghi MK. Hypophysitis: a single-center case series. Pituitary. 2015 Oct; 18(5):630-41. PMID: 25534888.
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Jahangiri A, Wagner JR, Han SW, Tran MT, Miller LM, Chen R, Tom MW, Ostling LR, Kunwar S, Blevins L, Aghi MK. Improved versus worsened endocrine function after transsphenoidal surgery for nonfunctional pituitary adenomas: rate, time course, and radiological analysis. J Neurosurg. 2016 Mar; 124(3):589-95. PMID: 26252454.
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Rutkowski MJ, Breshears JD, Kunwar S, Aghi MK, Blevins LS. Approach to the postoperative patient with Cushing's disease. Pituitary. 2015 Apr; 18(2):232-7. PMID: 25702104.
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Jahangiri A, Wagner JR, Chin AT, Han SW, Tran MT, Miller LM, Tom MW, Chen R, Kunwar S, Blevins L, Aghi MK. Incidence of headache as a presenting complaint in over 1000 patients with sellar lesions and factors predicting postoperative improvement. Clin Neurol Neurosurg. 2015 May; 132:16-20. PMID: 25746316.
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Zygourakis CC, Rolston JD, Lee HS, Partow C, Kunwar S, Aghi MK. Pituicytomas and spindle cell oncocytomas: modern case series from the University of California, San Francisco. Pituitary. 2015 Feb; 18(1):150-8. PMID: 24823438.
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Jahangiri A, Chin AT, Wagner JR, Kunwar S, Ames C, Chou D, Barani I, Parsa AT, McDermott MW, Benet A, El-Sayed IH, Aghi MK. Factors predicting recurrence after resection of clival chordoma using variable surgical approaches and radiation modalities. Neurosurgery. 2015 Feb; 76(2):179-85; discussion 185-6. PMID: 25594191.
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Cheng JS, Salinas R, Molinaro A, Chang EF, Kunwar S, Blevins L, Aghi MK. A predictive algorithm for evaluating elevated serum prolactin in patients with a sellar mass. J Clin Neurosci. 2015 Jan; 22(1):155-60. PMID: 25481269.
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Jahangiri A, Wagner J, Han SW, Tran MT, Miller LM, Tom MW, Ostling LR, Kunwar S, Blevins L, Aghi MK. Rate and time course of improvement in endocrine function after more than 1000 pituitary operations. Neurosurgery. 2014 Aug; 61 Suppl 1:163-6. PMID: 25032545.
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Zygourakis CC, Kaur G, Kunwar S, McDermott MW, Madden M, Oh T, Parsa AT. Modern treatment of 84 newly diagnosed craniopharyngiomas. J Clin Neurosci. 2014 Sep; 21(9):1558-66. PMID: 24908374.
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Jahangiri A, Wagner J, Han SW, Zygourakis CC, Han SJ, Tran MT, Miller LM, Tom MW, Kunwar S, Blevins LS, Aghi MK. Morbidity of repeat transsphenoidal surgery assessed in more than 1000 operations. J Neurosurg. 2014 Jul; 121(1):67-74. PMID: 24834943.
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Sheehan JP, Starke RM, Kano H, Kaufmann AM, Mathieu D, Zeiler FA, West M, Chao ST, Varma G, Chiang VL, Yu JB, McBride HL, Nakaji P, Youssef E, Honea N, Rush S, Kondziolka D, Lee JY, Bailey RL, Kunwar S, Petti P, Lunsford LD. Gamma Knife radiosurgery for sellar and parasellar meningiomas: a multicenter study. J Neurosurg. 2014 Jun; 120(6):1268-77. PMID: 24678777.
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Potts MB, Shah JK, Molinaro AM, Blevins LS, Tyrrell JB, Kunwar S, Dowd CF, Hetts SW, Aghi MK. Cavernous and inferior petrosal sinus sampling and dynamic magnetic resonance imaging in the preoperative evaluation of Cushing's disease. J Neurooncol. 2014 Feb; 116(3):593-600. PMID: 24398617.
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Jahangiri A, Potts M, Kunwar S, Blevins L, El-Sayed IH, Aghi MK. Extended endoscopic endonasal approach for suprasellar Rathke's cleft cysts. J Clin Neurosci. 2014 May; 21(5):779-85. PMID: 24308953.
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Breshears JD, Jiang B, Rowland NC, Kunwar S, Blevins LS. Use of conivaptan for management of hyponatremia following surgery for Cushing's disease. Clin Neurol Neurosurg. 2013 Nov; 115(11):2358-61. PMID: 24041963.
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Jahangiri A, Wagner J, Tran MT, Miller LM, Tom MW, Kunwar S, Blevins L, Aghi MK. Factors predicting postoperative hyponatremia and efficacy of hyponatremia management strategies after more than 1000 pituitary operations. J Neurosurg. 2013 Dec; 119(6):1478-83. PMID: 23971964.
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Jahangiri A, Clark AJ, Han SJ, Kunwar S, Blevins LS, Aghi MK. Socioeconomic factors associated with pituitary apoplexy. J Neurosurg. 2013 Dec; 119(6):1432-6. PMID: 23889139.
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Jahangiri A, Wagner JR, Pekmezci M, Hiniker A, Chang EF, Kunwar S, Blevins L, Aghi MK. A comprehensive long-term retrospective analysis of silent corticotrophic adenomas vs hormone-negative adenomas. Neurosurgery. 2013 Jul; 73(1):8-17; discussion 17-8. PMID: 23685641.
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Oh MC, Tihan T, Kunwar S, Blevins L, Aghi MK. Clinical management of pituitary carcinomas. Neurosurg Clin N Am. 2012 Oct; 23(4):595-606. PMID: 23040746.
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Oh MC, Kunwar S, Blevins L, Aghi MK. Medical versus surgical management of prolactinomas. Neurosurg Clin N Am. 2012 Oct; 23(4):669-78. PMID: 23040751.
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Potts MB, Jahangiri A, Lamborn KR, Blevins LS, Kunwar S, Aghi MK. Suprasellar Rathke cleft cysts: clinical presentation and treatment outcomes. Neurosurgery. 2011 Nov; 69(5):1058-68; discussion 1068-7. PMID: 21673610.
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Jahangiri A, Lamborn KR, Blevins L, Kunwar S, Aghi MK. Factors associated with delay to pituitary adenoma diagnosis in patients with visual loss. J Neurosurg. 2012 Feb; 116(2):283-9. PMID: 21740118.
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Jahangiri A, Molinaro AM, Tarapore PE, Blevins L, Auguste KI, Gupta N, Kunwar S, Aghi MK. Rathke cleft cysts in pediatric patients: presentation, surgical management, and postoperative outcomes. Neurosurg Focus. 2011 Jul; 31(1):E3. PMID: 21721868.
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Tarapore PE, Sughrue ME, Blevins L, Auguste KI, Gupta N, Kunwar S. Microscopic endonasal transsphenoidal pituitary adenomectomy in the pediatric population. J Neurosurg Pediatr. 2011 May; 7(5):501-9. PMID: 21529190.
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Petti PL, Kunwar S, Larson DA. A theoretical investigation of optimal target-dose conformity in gamma knife radiosurgery. Med Phys. 2011 May; 38(5):2812-9. PMID: 21776818.
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Ma L, Petti P, Wang B, Descovich M, Chuang C, Barani IJ, Kunwar S, Shrieve DC, Sahgal A, Larson DA. Apparatus dependence of normal brain tissue dose in stereotactic radiosurgery for multiple brain metastases. J Neurosurg. 2011 Jun; 114(6):1580-4. PMID: 21375377.
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Chang EF, Sughrue ME, Zada G, Wilson CB, Blevins LS, Kunwar S. Long term outcome following repeat transsphenoidal surgery for recurrent endocrine-inactive pituitary adenomas. Pituitary. 2010 Sep; 13(3):223-9. PMID: 20217484.
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Tate MC, Jahangiri A, Blevins L, Kunwar S, Aghi MK. Infected Rathke cleft cysts: distinguishing factors and factors predicting recurrence. Neurosurgery. 2010 Sep; 67(3):762-9; discussion 769. PMID: 20651624.
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Sughrue ME, Shah JK, Devin JK, Kunwar S, Blevins LS. Utility of the immediate postoperative cortisol concentrations in patients with Cushing's disease. Neurosurgery. 2010 Sep; 67(3):688-95; discussion 695. PMID: 20651632.
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Sampson JH, Archer G, Pedain C, Wembacher-Schröder E, Westphal M, Kunwar S, Vogelbaum MA, Coan A, Herndon JE, Raghavan R, Brady ML, Reardon DA, Friedman AH, Friedman HS, Rodríguez-Ponce MI, Chang SM, Mittermeyer S, Croteau D, Puri RK. Poor drug distribution as a possible explanation for the results of the PRECISE trial. J Neurosurg. 2010 Aug; 113(2):301-9. PMID: 20020841.
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Clark AJ, Lu DC, Richardson RM, Tihan T, Parsa AT, Chou D, Barbaro NM, Kunwar S, Weinstein PR, Lawton MT, Berger MS, McDermott MW. Surgical technique of temporary arterial occlusion in the operative management of spinal hemangioblastomas. World Neurosurg. 2010 Jul; 74(1):200-5. PMID: 21300014.
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Phillips JJ, Misra A, Feuerstein BG, Kunwar S, Tihan T. Pituicytoma: characterization of a unique neoplasm by histology, immunohistochemistry, ultrastructure, and array-based comparative genomic hybridization. Arch Pathol Lab Med. 2010 Jul; 134(7):1063-9. PMID: 20586639.
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Mueller S, Polley MY, Lee B, Kunwar S, Pedain C, Wembacher-Schröder E, Mittermeyer S, Westphal M, Sampson JH, Vogelbaum MA, Croteau D, Chang SM. Effect of imaging and catheter characteristics on clinical outcome for patients in the PRECISE study. J Neurooncol. 2011 Jan; 101(2):267-77. PMID: 20563833.
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Kunwar S, Chang S, Westphal M, Vogelbaum M, Sampson J, Barnett G, Shaffrey M, Ram Z, Piepmeier J, Prados M, Croteau D, Pedain C, Leland P, Husain SR, Joshi BH, Puri RK. Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma. Neuro Oncol. 2010 Aug; 12(8):871-81. PMID: 20511192.
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Blevins LS, Sanai N, Kunwar S, Devin JK. An approach to the management of patients with residual Cushing's disease. J Neurooncol. 2009 Sep; 94(3):313-9. PMID: 19381447.
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Sughrue ME, Chang EF, Tyrell JB, Kunwar S, Wilson CB, Blevins LS. Pre-operative dopamine agonist therapy improves post-operative tumor control following prolactinoma resection. Pituitary. 2009; 12(3):158-64. PMID: 18651225.
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Petti PL, Larson DA, Kunwar S. Use of hybrid shots in planning Perfexion Gamma Knife treatments for lesions close to critical structures. J Neurosurg. 2008 Dec; 109 Suppl:34-40. PMID: 19123886.
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Golden DW, Lamborn KR, McDermott MW, Kunwar S, Wara WM, Nakamura JL, Sneed PK. Prognostic factors and grading systems for overall survival in patients treated with radiosurgery for brain metastases: variation by primary site. J Neurosurg. 2008 Dec; 109 Suppl:77-86. PMID: 19123892.
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Huang K, Sneed PK, Kunwar S, Kragten A, Larson DA, Berger MS, Chan A, Pouliot J, McDermott MW. Surgical resection and permanent iodine-125 brachytherapy for brain metastases. J Neurooncol. 2009 Jan; 91(1):83-93. PMID: 18719856.
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Sampson JH, Akabani G, Archer GE, Berger MS, Coleman RE, Friedman AH, Friedman HS, Greer K, Herndon JE, Kunwar S, McLendon RE, Paolino A, Petry NA, Provenzale JM, Reardon DA, Wong TZ, Zalutsky MR, Pastan I, Bigner DD. Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors. Neuro Oncol. 2008 Jun; 10(3):320-9. PMID: 18403491.
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Chang EF, Zada G, Kim S, Lamborn KR, Quinones-Hinojosa A, Tyrrell JB, Wilson CB, Kunwar S. Long-term recurrence and mortality after surgery and adjuvant radiotherapy for nonfunctional pituitary adenomas. J Neurosurg. 2008 Apr; 108(4):736-45. PMID: 18377253.
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Sanai N, Quiñones-Hinojosa A, Narvid J, Kunwar S. Safety and efficacy of the direct endonasal transsphenoidal approach for challenging sellar tumors. J Neurooncol. 2008 May; 87(3):317-25. PMID: 18094936.
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Niestemski FC, Kunwar S, Zhou S, Li S, Ding H, Wang Z, Dai P, Madhavan V. A distinct bosonic mode in an electron-doped high-transition-temperature superconductor. Nature. 2007 Dec 13; 450(7172):1058-61. PMID: 18075588.
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Roy S, Josephson SA, Fridlyand J, Karch J, Kadoch C, Karrim J, Damon L, Treseler P, Kunwar S, Shuman MA, Jones T, Becker CH, Schulman H, Rubenstein JL. Protein biomarker identification in the CSF of patients with CNS lymphoma. J Clin Oncol. 2008 Jan 01; 26(1):96-105. PMID: 18056677.
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Vogelbaum MA, Sampson JH, Kunwar S, Chang SM, Shaffrey M, Asher AL, Lang FF, Croteau D, Parker K, Grahn AY, Sherman JW, Husain SR, Puri RK. Convection-enhanced delivery of cintredekin besudotox (interleukin-13-PE38QQR) followed by radiation therapy with and without temozolomide in newly diagnosed malignant gliomas: phase 1 study of final safety results. Neurosurgery. 2007 Nov; 61(5):1031-7; discussion 1037-8. PMID: 18091279.
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Wang VY, Barbaro NM, Lawton MT, Pitts L, Kunwar S, Parsa AT, Gupta N, McDermott MW. Complications of lumboperitoneal shunts. Neurosurgery. 2007 Jun; 60(6):1045-8; discussion 1049. PMID: 17538378.
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Kunwar S, Prados MD, Chang SM, Berger MS, Lang FF, Piepmeier JM, Sampson JH, Ram Z, Gutin PH, Gibbons RD, Aldape KD, Croteau DJ, Sherman JW, Puri RK. Direct intracerebral delivery of cintredekin besudotox (IL13-PE38QQR) in recurrent malignant glioma: a report by the Cintredekin Besudotox Intraparenchymal Study Group. J Clin Oncol. 2007 Mar 01; 25(7):837-44. PMID: 17327604.
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Chang S, Vogelbaum M, Lang FF, Haines S, Kunwar S, Chiocca EA, Olivi A, Quinones-Hinojosa A, Parsa A, Warnick R. GNOSIS: guidelines for neuro-oncology: standards for investigational studies--reporting of surgically based therapeutic clinical trials. J Neurooncol. 2007 Apr; 82(2):211-20. PMID: 17146595.
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Chi JH, Parsa AT, Berger MS, Kunwar S, McDermott MW. Extended bifrontal craniotomy for midline anterior fossa meningiomas: minimization of retraction-related edema and surgical outcomes. Neurosurgery. 2006 Oct; 59(4 Suppl 2):ONS426-33; discussion ONS433-4. PMID: 17041513.
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Chi JH, Sughrue M, Kunwar S, Lawton MT. The "yo-yo" technique to prevent cerebrospinal fluid rhinorrhea after anterior clinoidectomy for proximal internal carotid artery aneurysms. Neurosurgery. 2006 Jul; 59(1 Suppl 1):ONS101-7; discussion ONS101-7. PMID: 16888539.
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Kioi M, Husain SR, Croteau D, Kunwar S, Puri RK. Convection-enhanced delivery of interleukin-13 receptor-directed cytotoxin for malignant glioma therapy. Technol Cancer Res Treat. 2006 Jun; 5(3):239-50. PMID: 16700620.
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Kunwar S, Chang SM, Prados MD, Berger MS, Sampson JH, Croteau D, Sherman JW, Grahn AY, Shu VS, Dul JL, Husain SR, Joshi BH, Pedain C, Puri RK. Safety of intraparenchymal convection-enhanced delivery of cintredekin besudotox in early-phase studies. Neurosurg Focus. 2006 Apr 15; 20(4):E15. PMID: 16709020.
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Sampson JH, Akabani G, Friedman AH, Bigner D, Kunwar S, Berger MS, Bankiewicz KS. Comparison of intratumoral bolus injection and convection-enhanced delivery of radiolabeled antitenascin monoclonal antibodies. Neurosurg Focus. 2006 Apr 15; 20(4):E14. PMID: 16709019.
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Misra A, Pellarin M, Hu L, Kunwar S, Perhouse M, Lamborn KR, Deen DF, Feuerstein BG. Chromosome transfer experiments link regions on chromosome 7 to radiation resistance in human glioblastoma multiforme. Genes Chromosomes Cancer. 2006 Jan; 45(1):20-30. PMID: 16130123.
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Allmond LR, Stratmann G, Kunwar SM, Burkhardt DH. Epidural blood patch for headache after lumboperitoneal shunt placement. Anesth Analg. 2005 Nov; 101(5):1497-8. PMID: 16244018.
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Melisko ME, Kunwar S, Prados M, Berger MS, Park JW. Brain metastases of breast cancer. Expert Rev Anticancer Ther. 2005 Apr; 5(2):253-68. PMID: 15877523.
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Parney IF, Kunwar S, McDermott M, Berger M, Prados M, Cha S, Croteau D, Puri RK, Chang SM. Neuroradiographic changes following convection-enhanced delivery of the recombinant cytotoxin interleukin 13-PE38QQR for recurrent malignant glioma. J Neurosurg. 2005 Feb; 102(2):267-75. PMID: 15739554.
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Liu C, Lo JC, Dowd CF, Wilson CB, Kunwar S, Aron DC, Tyrrell JB. Cavernous and inferior petrosal sinus sampling in the evaluation of ACTH-dependent Cushing's syndrome. Clin Endocrinol (Oxf). 2004 Oct; 61(4):478-86. PMID: 15473881.
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McDermott MW, Berger MS, Kunwar S, Parsa AT, Sneed PK, Larson DA. Stereotactic radiosurgery and interstitial brachytherapy for glial neoplasms. J Neurooncol. 2004 Aug-Sep; 69(1-3):83-100. PMID: 15527082.
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Sanai N, Tramontin AD, Quiñones-Hinojosa A, Barbaro NM, Gupta N, Kunwar S, Lawton MT, McDermott MW, Parsa AT, Manuel-García Verdugo J, Berger MS, Alvarez-Buylla A. Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration. Nature. 2004 Feb 19; 427(6976):740-4. PMID: 14973487.
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Kunwar S. Endoscopic adjuncts to intraventricular surgery. Neurosurg Clin N Am. 2003 Oct; 14(4):547-57. PMID: 15024800.
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Sampson JH, Akabani G, Archer GE, Bigner DD, Berger MS, Friedman AH, Friedman HS, Herndon JE, Kunwar S, Marcus S, McLendon RE, Paolino A, Penne K, Provenzale J, Quinn J, Reardon DA, Rich J, Stenzel T, Tourt-Uhlig S, Wikstrand C, Wong T, Williams R, Yuan F, Zalutsky MR, Pastan I. Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors. J Neurooncol. 2003 Oct; 65(1):27-35. PMID: 14649883.
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Lang FF, Bruner JM, Fuller GN, Aldape K, Prados MD, Chang S, Berger MS, McDermott MW, Kunwar SM, Junck LR, Chandler W, Zwiebel JA, Kaplan RS, Yung WK. Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results. J Clin Oncol. 2003 Jul 01; 21(13):2508-18. PMID: 12839017.
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Kunwar S. Convection enhanced delivery of IL13-PE38QQR for treatment of recurrent malignant glioma: presentation of interim findings from ongoing phase 1 studies. Acta Neurochir Suppl. 2003; 88:105-11. PMID: 14531568.
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Larson DA, Prados M, Lamborn KR, Smith V, Sneed PK, Chang S, Nicholas KM, Wara WM, Devriendt D, Kunwar S, Berger M, McDermott MW. Phase II study of high central dose Gamma Knife radiosurgery and marimastat in patients with recurrent malignant glioma. Int J Radiat Oncol Biol Phys. 2002 Dec 01; 54(5):1397-404. PMID: 12459362.
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Kunwar S, Mohapatra G, Bollen A, Lamborn KR, Prados M, Feuerstein BG. Genetic subgroups of anaplastic astrocytomas correlate with patient age and survival. Cancer Res. 2001 Oct 15; 61(20):7683-8. PMID: 11606412.
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Kunwar S, Wilson CB. Pediatric pituitary adenomas. J Clin Endocrinol Metab. 1999 Dec; 84(12):4385-9. PMID: 10599692.
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Prior TI, Kunwar S, Pastan I. Studies on the activity of barnase toxins in vitro and in vivo. Bioconjug Chem. 1996 Jan-Feb; 7(1):23-9. PMID: 8741987.
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Kunwar S, Pai LH, Pastan I. Cytotoxicity and antitumor effects of growth factor-toxin fusion proteins on human glioblastoma multiforme cells. J Neurosurg. 1993 Oct; 79(4):569-76. PMID: 7692018.
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Pastan I, Lovelace E, Rutherford AV, Kunwar S, Willingham MC, Peehl DM. PR1--a monoclonal antibody that reacts with an antigen on the surface of normal and malignant prostate cells. J Natl Cancer Inst. 1993 Jul 21; 85(14):1149-54. PMID: 7686582.
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Brinkmann U, Gallo M, Brinkmann E, Kunwar S, Pastan I. A recombinant immunotoxin that is active on prostate cancer cells and that is composed of the Fv region of monoclonal antibody PR1 and a truncated form of Pseudomonas exotoxin. Proc Natl Acad Sci U S A. 1993 Jan 15; 90(2):547-51. PMID: 8421689.
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