Sangeetha Omprakash Kandoi, PhD

Title(s)Postdoctoral Scholar, Ophthalmology
SchoolSchool of Medicine
Address35 Medical Center Way, #913A
San Francisco CA 94143
Phone--
Emailsangeetha.kandoi@ucsf.edu
ORCID ORCID Icon0000-0001-8346-8642 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Indian Institute of Technology Madras, Chennai, IndiaPhD03/2019Stem Cells & Cardiomyopathy
    Bharathidasan University, IndiaMaster of Philosophy12/2006Mirobiology
    University of Madras, Chennai, IndiaMaster of Science04/2004Applied Microbiology
    University of Madras, Chennai, IndiaBachelor of Science04/2002Microbiology
    Collapse Awards and Honors
    National Alliance for Eye and Vision Research (NAEVR)/Alliance for Eye and Vision Research (AEVR)2023Emerging Vision Scientist
    BrightFocus Foundation (Macular Degeneration Research)2023  - 2025Postdoctoral Fellowship
    Tree Shrew Discovery 2023 Meeting, Florida, USA2023Travel Grant & Contributed Talk
    All May See Foundation2023  - 2023Postdoctoral Fellowship
    University of California San Francisco2022Top Ten Finalist and People’s choice winner award at the UCSF Postdoc Slam Contest
    UCSF Department of Ophthalmology 2022First Prize in Trainee presentation, Research Day
    ARVO 2022 Annual Meeting, Denver, USA2022Retina Research Foundation/Joseph M. and Eula C. Lawrence Travel Grant
    XIXth International Symposium on Retinal Degenerations 2021 Meeting2021Retinal Degenerations and the BrightFocus Macular Fast TrackSM Travel Fellowship
    ARVO 2021 Annual Meeting2021American Macular Degeneration Foundation Travel Grant

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Modeling Retinitis Pigmentosa using patient-derived human iPSC organoids
    California Institute of Regenerative Medicine (CIRM) DISC0-14449Jul 1, 2023 - Jun 20, 2026
    Role: Post-doctoral Scholar
    Description: The purpose of this study is to generate a 3D retinal organoid model of adRP due to copy number variants and P23H in the RHO gene using patient-derived iPSC lines to decipher the pathogenesis and to design novel therapeutic strategies.
    Photoreceptor remodeling in the hibernating cone-dominant 13-lined ground squirrel as a model for macular degeneration in humans
    BrightFocus Foundation for Macular Degeneration Research M2023005FJul 1, 2023 - Jun 30, 2025
    Role: Principal Investigator
    Description: The goal of the study is to leverage the clinically relevant features of the squirrel model, to understand how squirrel photoreceptor, glial, and immune cells are involved in overcoming hibernation stress, an understanding that could lead to novel therapies for AMD.
    Retinal organoid-based modeling and gene editing for GUCY2D-associated Cone Rod dystrophy
    All May See Foundation Jul 1, 2023 - Jun 30, 2024
    Role: Principal Investigator
    Description: The purpose of this study is to develop a novel GUCY2D-CORD6 variants’ model-in-a-dish and compare them with a gene edited counterpart cell line for the development of future clinical therapies.
    Developing Cone-Dominant Retinal Disease Models as a Resource for Translational Vision Research
    NEI/NIH U24EY029891Sep 30, 2018 - Aug 31, 2023
    Role: Post-doctoral Scholar
    Description: The purpose of this study is to assess cell replacement strategies in alternative species like 13-lined ground squirrels and Tree shrews.

    Collapse ORNG Applications 
    Collapse Featured Publications
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Retinal Organoids: A Human Model System for Development, Diseases, and Therapies. Adv Exp Med Biol. 2023; 1415:549-554. Kandoi S, Lamba DA. PMID: 37440085.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Characterization of Retinal Development in 13-Lined Ground Squirrels. Transl Vis Sci Technol. 2022 11 01; 11(11):17. Kandoi S, Martinez C, Merriman DK, Lamba DA. PMID: 36409292; PMCID: PMC9695149.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    3. Timed Notch Inhibition Drives Photoreceptor Fate Specification in Human Retinal Organoids. Invest Ophthalmol Vis Sci. 2022 09 01; 63(10):12. Chew SH, Martinez C, Chirco KR, Kandoi S, Lamba DA. PMID: 36129723; PMCID: PMC9513742.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    4. Biophysical, Molecular and Proteomic Profiling of Human Retinal Organoid-Derived Exosomes. Pharm Res. 2023 Apr; 40(4):801-816. Arthur P, Kandoi S, Sun L, Kalvala A, Kutlehria S, Bhattacharya S, Kulkarni T, Nimma R, Li Y, Lamba DA, Singh M. PMID: 36002615; PMCID: PMC10576571.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    5. An enhancer located in a Pde6c intron drives transient expression in the cone photoreceptors of developing mouse and human retinas. Dev Biol. 2022 08; 488:131-150. Bachu VS, Kandoi S, Park KU, Kaufman ML, Schwanke M, Lamba DA, Brzezinski JA. PMID: 35644251.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. Generation and transplantation of hepatocytes-like cells using human origin hepatogenic serum for acute liver injury treatment. Xenotransplantation. 2022 03; 29(2):e12730. Gupta S, Sharma A, Paneerselvan S, Kandoi S, Patra B, Bishi DK, Verma RS. PMID: 35166406.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. The mesenchymal stem cell secretome: A new paradigm towards cell-free therapeutic mode in regenerative medicine. Cytokine Growth Factor Rev. 2019 04; 46:1-9. L PK, Kandoi S, Misra R, S V, K R, Verma RS. PMID: 30954374.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansAnimalsCells
    8. Evaluation of platelet lysate as a substitute for FBS in explant and enzymatic isolation methods of human umbilical cord MSCs. Sci Rep. 2018 08 20; 8(1):12439. Kandoi S, L PK, Patra B, Vidyasekar P, Sivanesan D, S V, K R, Verma RS. PMID: 30127445; PMCID: PMC6102222.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    9. Association of Cardiomyopathy With MYBPC3 D389V and MYBPC3Δ25bpIntronic Deletion in South Asian Descendants. JAMA Cardiol. 2018 06 01; 3(6):481-488. Viswanathan SK, Puckelwartz MJ, Mehta A, Ramachandra CJA, Jagadeesan A, Fritsche-Danielson R, Bhat RV, Wong P, Kandoi S, Schwanekamp JA, Kuffel G, Pesce LL, Zilliox MJ, Durai UNB, Verma RS, Molokie RE, Suresh DP, Khoury PR, Thomas A, Sanagala T, Tang HC, Becker RC, Knöll R, Shim W, McNally EM, Sadayappan S. PMID: 29641836; PMCID: PMC6054452.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
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