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Sanket Dhruva, MD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
Phone415-221-4810 ext. 22689
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bartlett VL, Dhruva SS, Shah ND, Ryan P, Ross JS. Feasibility of Using Real-World Data to Replicate Clinical Trial Evidence. JAMA Netw Open. 2019 Oct 02; 2(10):e1912869. PMID: 31596493.
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    2. Dayoub EJ, Ross JS, Shah ND, Dhruva SS. Evolution of Medicare Formulary Coverage Changes for Antithrombotic Therapies After Guideline Updates. Circulation. 2019 Oct; 140(14):1227-1230. PMID: 31567008.
      View in: PubMed
    3. DuBose-Briski V, Yao X, Dunlay SM, Dhruva SS, Ross JS, Shah ND, Noseworthy PA. Evolution of the American College of Cardiology and American Heart Association Cardiology Clinical Practice Guidelines: A 10-Year Assessment. J Am Heart Assoc. 2019 Oct; 8(19):e012065. PMID: 31566106.
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    4. Morgan DJ, Dhruva SS, Coon ER, Wright SM, Korenstein D. 2019 Update on Medical Overuse: A Review. JAMA Intern Med. 2019 Sep 09. PMID: 31498374.
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    5. Shahu A, Herrin J, Dhruva SS, Desai NR, Davis BR, Krumholz HM, Spatz ES. Disparities in Socioeconomic Context and Association With Blood Pressure Control and Cardiovascular Outcomes in ALLHAT. J Am Heart Assoc. 2019 Aug 06; 8(15):e012277. PMID: 31362591.
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    6. Redberg RF, Dhruva SS. Moving From Substantial Equivalence to Substantial Improvement for 510(k) Devices. JAMA. 2019 Jul 29. PMID: 31355877.
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    7. Egilman AC, Wallach JD, Dhruva SS, Gonsalves GS, Ross JS. Medicare Spending on Drugs and Biologics Not Recommended for Coverage by International Health Technology Assessment Agencies. J Gen Intern Med. 2019 Jul 16. PMID: 31313117.
      View in: PubMed
    8. Shaw LJ, Blankstein R, Brown DL, Dhruva SS, Douglas PS, Genders TSS, Gibbons RJ, Greenwood JP, Kwong R, Leipsic J, Mahmarian JJ, Maron D, Nagel E, Nicol E, Nieman K, Pellikka PA, Redberg RF, Weir-McCall J, Williams MC, Chandrasekhar Y. Controversies in Diagnostic Imaging of Patients With Suspected Stable and Acute Chest Pain Syndromes. JACC Cardiovasc Imaging. 2019 Jul; 12(7 Pt 1):1254-1278. PMID: 31272608.
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    9. Wallach JD, Luxkaranayagam AT, Dhruva SS, Miller JE, Ross JS. Postmarketing commitments for novel drugs and biologics approved by the US Food and Drug Administration: a cross-sectional analysis. BMC Med. 2019 06 17; 17(1):117. PMID: 31203816.
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    10. Judson TJ, Dhruva SS, Redberg RF. Evaluation of technologies approved for supplemental payments in the United States. BMJ. 2019 06 17; 365:l2190. PMID: 31209124.
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    11. Skydel JJ, Luxkaranayagam AT, Dhruva SS, Ross JS, Wallach JD. Analysis of Postapproval Clinical Trials of Therapeutics Approved by the US Food and Drug Administration Without Clinical Postmarketing Requirements or Commitments. JAMA Netw Open. 2019 May 03; 2(5):e193410. PMID: 31074812.
      View in: PubMed
    12. Morgan DJ, Dhruva SS, Korenstein D. Clinical Interpretation of High-Sensitivity Troponin Testing-Reply. JAMA Intern Med. 2019 May 01; 179(5):726. PMID: 31058941.
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    13. Vijay A, Ross JS, Shah ND, Jeffery MM, Dhruva SS. Medicare Formulary Coverage and Restrictions for Opioid Potentiators from 2013 to 2017. J Gen Intern Med. 2019 Apr; 34(4):518-520. PMID: 30623386.
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    14. Coon ER, Quinonez RA, Morgan DJ, Dhruva SS, Ho T, Money N, Schroeder AR. 2018 Update on Pediatric Medical Overuse: A Review. JAMA Pediatr. 2019 Apr 01; 173(4):379-384. PMID: 30776069.
      View in: PubMed
    15. Morgan DJ, Dhruva SS, Coon ER, Wright SM, Korenstein D. 2018 Update on Medical Overuse. JAMA Intern Med. 2019 Feb 01; 179(2):240-246. PMID: 30508032.
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    16. Dhruva SS. Implementation of an EConsult System with Patient Navigation. J Health Care Poor Underserved. 2019; 30(1):28-39. PMID: 30827966.
      View in: PubMed
    17. Shaw DL, Dhruva SS, Ross JS. Coverage of Novel Therapeutic Agents by Medicare Prescription Drug Plans Following FDA Approval. J Manag Care Spec Pharm. 2018 Dec; 24(12):1230-1238. PMID: 30479199.
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    18. Huang C, Murugiah K, Mahajan S, Li SX, Dhruva SS, Haimovich JS, Wang Y, Schulz WL, Testani JM, Wilson FP, Mena CI, Masoudi FA, Rumsfeld JS, Spertus JA, Mortazavi BJ, Krumholz HM. Enhancing the prediction of acute kidney injury risk after percutaneous coronary intervention using machine learning techniques: A retrospective cohort study. PLoS Med. 2018 11; 15(11):e1002703. PMID: 30481186.
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    19. Dhruva SS, Ross JS, Desai NR. Alirocumab's Price Reduction. Circulation. 2018 10 09; 138(15):1502-1504. PMID: 30354510.
      View in: PubMed
    20. Roginiel AC, Dhruva SS, Ross JS. Evidence supporting FDA approval and CMS national coverage determinations for novel medical products, 2005 through 2016: A cross-sectional study. Medicine (Baltimore). 2018 Oct; 97(40):e12715. PMID: 30290675.
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    21. Jones LC, Dhruva SS, Redberg RF. Assessment of Clinical Trial Evidence for High-Risk Cardiovascular Devices Approved Under the Food and Drug Administration Priority Review Program. JAMA Intern Med. 2018 Oct 01; 178(10):1418-1420. PMID: 30178044.
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    22. Sedrakyan A, Dhruva SS, Sun T, Mao J, Gaudino MFL, Redberg RF. Trends in Use of Transcatheter Aortic Valve Replacement by Age. JAMA. 2018 Aug 14; 320(6):598-600. PMID: 30039166.
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    23. Welsh J, Lu Y, Dhruva SS, Bikdeli B, Desai NR, Benchetrit L, Zimmerman CO, Mu L, Ross JS, Krumholz HM. Age of Data at the Time of Publication of Contemporary Clinical Trials. JAMA Netw Open. 2018 08 03; 1(4):e181065. PMID: 30646100.
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    24. Dhruva SS, Ross JS, Desai NR. Real-World Evidence: Promise and Peril For Medical Product Evaluation. P T. 2018 Aug; 43(8):464-472. PMID: 30100687.
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    25. Liu P, Dhruva SS, Shah ND, Ross JS. Medicare Beneficiary Out-of-Pocket Costs for Generic Cardiovascular Medications Available Through $4 Generic Drug Discount Programs. Ann Intern Med. 2018 12 04; 169(11):817-819. PMID: 30039170.
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    26. Warner F, Dhruva SS, Ross JS, Dey P, Murugiah K, Krumholz HM. Accurate estimation of cardiovascular risk in a non-diabetic adult: detecting and correcting the error in the reported Framingham Risk Score for the Systolic Blood Pressure Intervention Trial population. BMJ Open. 2018 07 23; 8(7):e021685. PMID: 30037874.
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    27. Dhruva SS. Continuing to Improve Appropriateness of Continuous Electrocardiographic Monitoring (Telemetry). JAMA Intern Med. 2018 07 01; 178(7):978-979. PMID: 29868799.
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    28. Bates J, Parzynski CS, Dhruva SS, Coppi A, Kuntz R, Li SX, Marinac-Dabic D, Masoudi FA, Shaw RE, Warner F, Krumholz HM, Ross JS. Quantifying the utilization of medical devices necessary to detect postmarket safety differences: A case study of implantable cardioverter defibrillators. Pharmacoepidemiol Drug Saf. 2018 08; 27(8):848-856. PMID: 29896873.
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    29. Dhruva SS, Ross JS, Schulz WL, Krumholz HM. Fulfilling the Promise of Unique Device Identifiers. Ann Intern Med. 2018 08 07; 169(3):183-185. PMID: 29868760.
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    30. Wallach JD, Egilman AC, Dhruva SS, McCarthy ME, Miller JE, Woloshin S, Schwartz LM, Ross JS. Postmarket studies required by the US Food and Drug Administration for new drugs and biologics approved between 2009 and 2012: cross sectional analysis. BMJ. 2018 05 24; 361:k2031. PMID: 29794072.
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    31. Coon ER, Young PC, Quinonez RA, Morgan DJ, Dhruva SS, Schroeder AR. 2017 Update on Pediatric Medical Overuse: A Review. JAMA Pediatr. 2018 05 01; 172(5):482-486. PMID: 29582079.
      View in: PubMed
    32. Egilman AC, Wallach JD, Ross JS, Dhruva SS. Medicare Spending and Potential Savings on Brand-Name Drugs With Available Generic Substitutes Excluded by 2 Large Pharmacy Benefit Managers, 2012 Through 2015. JAMA Intern Med. 2018 04 01; 178(4):567-569. PMID: 29340562.
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    33. Morgan DJ, Dhruva SS, Korenstein D. Medical Overuse of Prostate-Specific Antigen Testing and Overprescription of Antibiotics-Reply. JAMA Intern Med. 2018 03 01; 178(3):432-433. PMID: 29507989.
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    34. Morgan DJ, Dhruva SS, Coon ER, Wright SM, Korenstein D. 2017 Update on Medical Overuse: A Systematic Review. JAMA Intern Med. 2018 01 01; 178(1):110-115. PMID: 28973402.
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    35. Solotke MT, Dhruva SS, Downing NS, Shah ND, Ross JS. New and incremental FDA black box warnings from 2008 to 2015. Expert Opin Drug Saf. 2018 Feb; 17(2):117-123. PMID: 29215916.
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    36. Huang C, Dhruva SS, Coppi AC, Warner F, Li SX, Lin H, Nasir K, Krumholz HM. Systolic Blood Pressure Response in SPRINT (Systolic Blood Pressure Intervention Trial) and ACCORD (Action to Control Cardiovascular Risk in Diabetes): A Possible Explanation for Discordant Trial Results. J Am Heart Assoc. 2017 Nov 13; 6(11). PMID: 29133522.
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    37. Foy AJ, Dhruva SS, Peterson B, Mandrola JM, Morgan DJ, Redberg RF. Coronary Computed Tomography Angiography vs Functional Stress Testing for Patients With Suspected Coronary Artery Disease: A Systematic Review and Meta-analysis. JAMA Intern Med. 2017 11 01; 177(11):1623-1631. PMID: 28973101.
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    38. Dhruva SS, Curtis JP. Requiem for a Scaffold. Ann Intern Med. 2017 11 07; 167(9):675-676. PMID: 29049832.
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    39. Samuels EA, Ross JS, Dhruva SS. Medicare Formulary Coverage Restrictions for Prescription Opioids, 2006 to 2015. Ann Intern Med. 2017 12 19; 167(12):895-896. PMID: 29052693.
      View in: PubMed
    40. Angraal S, Ross JS, Dhruva SS, Desai NR, Welsh JW, Krumholz HM. Merits of Data Sharing: The Digitalis Investigation Group Trial. J Am Coll Cardiol. 2017 10 03; 70(14):1825-1827. PMID: 28958337.
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    41. Gupta R, Dhruva SS, Fox ER, Ross JS. The FDA Unapproved Drugs Initiative: An Observational Study of the Consequences for Drug Prices and Shortages in the United States. J Manag Care Spec Pharm. 2017 Oct; 23(10):1066-1076. PMID: 28944731.
      View in: PubMed
    42. Dhruva SS, Karaca-Mandic P, Shah ND, Shaw DL, Ross JS. Association between FDA black box warnings and Medicare formulary coverage changes. Am J Manag Care. 2017 Sep 01; 23(9):e310-e315. PMID: 29087169.
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    43. Coon ER, Young PC, Quinonez RA, Morgan DJ, Dhruva SS, Schroeder AR. Author's Response. Pediatrics. 2017 09; 140(3). PMID: 28860137.
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    44. Dhruva SS, Mazure CM, Ross JS, Redberg RF. Inclusion of Demographic-Specific Information in Studies Supporting US Food & Drug Administration Approval of High-Risk Medical Devices. JAMA Intern Med. 2017 09 01; 177(9):1390-1391. PMID: 28738116.
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    45. Zheng SY, Dhruva SS, Redberg RF. Characteristics of Clinical Studies Used for US Food and Drug Administration Approval of High-Risk Medical Device Supplements. JAMA. 2017 Aug 15; 318(7):619-625. PMID: 28810022.
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    46. Dhruva SS, Huang C, Spatz ES, Coppi AC, Warner F, Li SX, Lin H, Xu X, Furberg CD, Davis BR, Pressel SL, Coifman RR, Krumholz HM. Heterogeneity in Early Responses in ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial). Hypertension. 2017 07; 70(1):94-102. PMID: 28559399.
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    47. Dhruva SS, Redberg RF. FDA Drug Trials Snapshots-A Clearer Picture. JAMA Intern Med. 2017 05 01; 177(5):727. PMID: 28288250.
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    48. Krumholz HM, Dhruva SS. Real-World Data on Heart Failure Readmission Reduction: Real or Real Uncertain? J Am Coll Cardiol. 2017 05 16; 69(19):2366-2368. PMID: 28330750.
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    49. Sedrakyan A, Dhruva SS, Shuhaiber J. Transcatheter Aortic Valve Replacement in Younger Individuals. JAMA Intern Med. 2017 02 01; 177(2):159-160. PMID: 28027340.
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    50. Dhruva SS, Redberg RF. Letter by Dhruva and Redberg Regarding Article, "Sex and Race/Ethnicity Differences in Implantable Cardioverter-Defibrillator Counseling and Use Among Patients Hospitalized With Heart Failure: Findings From the Get With The Guidelines-Heart Failure Program". Circulation. 2017 01 17; 135(3):e20-e21. PMID: 28093498.
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    51. Dhruva SS, Desai NR, Karaca-Mandic P, Shah ND, Ross JS. Medicare Formulary Changes After the 2013 American College of Cardiology/American Heart Association Cholesterol Guideline. J Am Coll Cardiol. 2017 01 17; 69(2):244-246. PMID: 28081832.
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    52. Coon ER, Young PC, Quinonez RA, Morgan DJ, Dhruva SS, Schroeder AR. Update on Pediatric Overuse. Pediatrics. 2017 Feb; 139(2). PMID: 28049113.
      View in: PubMed
    53. Morgan DJ, Dhruva SS, Wright SM, Korenstein D. 2016 Update on Medical Overuse: A Systematic Review. JAMA Intern Med. 2016 11 01; 176(11):1687-1692. PMID: 27654002.
      View in: PubMed
    54. Foy AJ, Dhruva SS, Mandrola J. For the Patient with "Low-risk Chest Pain"-How Low Is Low? Acad Radiol. 2016 12; 23(12):1587-1591. PMID: 27671908.
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    55. Dhruva SS, Redberg RF. Sex-Specific Data for the Subcutaneous Implantable Cardioverter-Defibrillator. J Am Coll Cardiol. 2016 07 05; 68(1):133. PMID: 27364060.
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    56. Dhruva SS, Krumholz HM. Championing Effectiveness Before Cost-Effectiveness. JACC Heart Fail. 2016 05; 4(5):376-9. PMID: 27039130.
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    57. Dhruva SS, Prasad V. Application of Medicare's New Technology Add-on Payment Program for Blinatumomab. JAMA Oncol. 2016 Feb; 2(2):165-6. PMID: 26720844.
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    58. Dhruva SS, Krumholz HM. The Core Value of Cost-Effectiveness Analyses. J Am Coll Cardiol. 2016 Jan 05; 67(1):39-41. PMID: 26764064.
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    59. Morgan DJ, Dhruva SS, Wright SM, Korenstein D. Update on Medical Practices That Should Be Questioned in 2015. JAMA Intern Med. 2015 Dec; 175(12):1960-4. PMID: 26551354.
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    60. Dhruva SS, Ross JS, Gariepy AM. Revisiting Essure--Toward Safe and Effective Sterilization. N Engl J Med. 2015 Oct 08; 373(15):e17. PMID: 26397951.
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    61. Morgan DJ, Brownlee S, Leppin AL, Kressin N, Dhruva SS, Levin L, Landon BE, Zezza MA, Schmidt H, Saini V, Elshaug AG. Setting a research agenda for medical overuse. BMJ. 2015 Aug 25; 351:h4534. PMID: 26306661.
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    62. Sab S, Dhruva SS, Paulsen J, Sidhu RS, Amsterdam EA, Venugopal S. Here Today, Gone Tomorrow. Am J Med. 2015 Dec; 128(12):e7-9. PMID: 26302138.
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    63. Chang L, Dhruva SS, Chu J, Bero LA, Redberg RF. Selective reporting in trials of high risk cardiovascular devices: cross sectional comparison between premarket approval summaries and published reports. BMJ. 2015 Jun 10; 350:h2613. PMID: 26063311.
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    64. Dhruva SS, Redberg RF. Evidence And Medicare's Coverage Of Interventions. Health Aff (Millwood). 2015 Jun; 34(6):1066. PMID: 26056214.
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    65. Morgan DJ, Wright SM, Dhruva S. Update on medical overuse. JAMA Intern Med. 2015 Jan; 175(1):120-4. PMID: 25365707.
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    66. Gartenberg AJ, Peleg A, Dhruva SS, Redberg RF. Presumed safe no more: lessons from the Wingspan saga on regulation of devices. BMJ. 2014 Jan 22; 348:g93. PMID: 24452627.
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    67. Baxi S, Platts-Mills J, Dhruva S, Huang L, Hanks D, Dhaliwal G. A double-edged sword. J Hosp Med. 2013 Jan; 8(1):47-51. PMID: 23293015.
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    68. Dhruva SS, Redberg RF. FDA regulation of cardiovascular devices and opportunities for improvement. J Interv Card Electrophysiol. 2013 Mar; 36(2):99-105. PMID: 23263896.
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    69. Chen CE, Dhruva SS, Redberg RF. Inclusion of comparative effectiveness data in high-risk cardiovascular device studies at the time of premarket approval. JAMA. 2012 Nov 07; 308(17):1740-2. PMID: 23117769.
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    70. Dhruva SS, Redberg RF. Medical device regulation: time to improve performance. PLoS Med. 2012; 9(7):e1001277. PMID: 22859912.
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    71. Dhruva SS, Redberg RF. Evaluating sex differences in medical device clinical trials: time for action. JAMA. 2012 Mar 21; 307(11):1145-6. PMID: 22378695.
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    72. Dhruva SS, Redberg RF. Withdrawing unsafe drugs from the market. Health Aff (Millwood). 2011 Nov; 30(11):2218. PMID: 22068420.
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    73. Dhruva SS, Redberg RF. Sex-specific outcomes for HeartMate II. J Am Coll Cardiol. 2011 Sep 13; 58(12):1285; author reply 1285-6. PMID: 21903068.
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    74. Redberg RF, Dhruva SS. Transcatheter aortic-valve replacement. N Engl J Med. 2011 09 08; 365(10):958-9; author reply 959. PMID: 21899458.
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    75. Dhruva SS, Redberg RF. Clinical trial enrollment and progress in women's health. JAMA. 2011 Mar 23; 305(12):1197; author reply 1197-8. PMID: 21427370.
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    76. Dhruva SS, Bero LA, Redberg RF. Gender bias in studies for Food and Drug Administration premarket approval of cardiovascular devices. Circ Cardiovasc Qual Outcomes. 2011 Mar; 4(2):165-71. PMID: 21364127.
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    77. Redberg RF, Dhruva SS. Medical device recalls: get it right the first time: Comment on "Medical device recalls and the FDA approval process". Arch Intern Med. 2011 Jun 13; 171(11):1011-2. PMID: 21321286.
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    78. Chen CE, Dhruva SS, Bero LA, Redberg RF. Inclusion of training patients in US Food and Drug Administration premarket approval cardiovascular device studies. Arch Intern Med. 2011 Mar 28; 171(6):534-9. PMID: 21098342.
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    79. Dhruva SS, Redberg RF. Accelerated approval and possible withdrawal of midodrine. JAMA. 2010 Nov 17; 304(19):2172-3. PMID: 21081731.
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    80. Dhruva SS, Redberg RF. The need for sex-specific data prior to food and drug administration approval. J Am Coll Cardiol. 2010 Jan 19; 55(3):261; author reply 261-2. PMID: 20117414.
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    81. Dhruva SS, Bero LA, Redberg RF. Strength of study evidence examined by the FDA in premarket approval of cardiovascular devices. JAMA. 2009 Dec 23; 302(24):2679-85. PMID: 20040556.
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    82. Dhruva SS, Phurrough SE, Salive ME, Redberg RF. CMS's landmark decision on CT colonography--examining the relevant data. N Engl J Med. 2009 Jun 25; 360(26):2699-701. PMID: 19474419.
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    83. Dhruva SS, Redberg RF. Variations between clinical trial participants and Medicare beneficiaries in evidence used for Medicare national coverage decisions. Arch Intern Med. 2008 Jan 28; 168(2):136-40. PMID: 18227358.
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