Sarah Puryear, MD, MPH

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
Address1001 Potrero Ave, #410
San Francisco CA 94110
ORCID ORCID Icon0000-0003-0669-3293 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Georgia, Athens, GABS05/2007Microbiology
    Johns Hopkins University School of Medicine, Baltimore, MDMD05/2013Medicine
    Johns Hopkins Hospital Osler Medical Residency, Baltimore, MDResidency06/2016Internal Medicine
    University of California, Berkeley, Berkeley, CAMPH06/2019Epidemiology
    University of California, San Francisco, San Francisco, CAFellowship09/2020Infectious Diseases
    Collapse Awards and Honors
    UCSF Division of Infectious Diseases2019Jane Koehler Award for Outstanding Fellowship Research in Infectious Diseases
    UCSF AIDS Research Institute2018  - 2020AIDS Research Institute Clinical Fellowship
    Center for AIDS Prevention Studies2018  - 2020Traineeship in AIDS Prevention Studies Fellowship
    Conference on Retroviruses and Opportunistic Infections2020Young Investigator Award
    UCSF Division of HIV, Infectious Diseases, & Global Medicine2022Teri Liegler Young Scientist Career Award

    Collapse Overview 
    Collapse Overview
    I am an infectious disease (ID) physician and clinical researcher whose work focuses on the intersection of alcohol, HIV, and tuberculosis in sub-Saharan Africa. I am currently an assistant professor in the Division of HIV, ID, and Global Medicine at the University of California, San Francisco (UCSF). I am trained in infectious diseases, HIV and TB prevention and epidemiology, and work as a physician in the Ward 86 HIV clinic and the inpatient Internal Medicine and HIV/ID consult services at San Francisco General Hospital. I have worked in research and public health programming in sub-Saharan Africa since 2007.

    My research focuses on defining HIV care outcomes and TB epidemiology among persons who engage in alcohol use, who are a high-risk group for poor outcomes and may benefit from novel service interventions. Currently, I am focused on understanding the epidemiology of alcohol use and its relationship to HIV care outcomes among youth living with HIV in sub-Saharan Africa with the ultimate goal of developing youth-specific, culturally appropriate alcohol interventions. Additionally, I am co-leading a randomized controlled trial within the SEARCH-Sapphire study (PIs: Havlir, Petersen, Kamya) to test a novel recruitment and intervention strategy to improve viral suppression among people living with HIV who have hazardous levels of alcohol use. Across my research, I am interested in leveraging alcohol biomarkers to better understand the measurement of alcohol use.

    Collapse Research 
    Collapse Research Activities and Funding
    Understanding alcohol misuse and its impact on viral suppression in youth living with HIV in East Africa
    NIH K23AA029045Sep 15, 2020 - Aug 31, 2025
    Role: Principal Investigator
    Validation of a Novel Blood-Based Alcohol Biomarker (Phosphatidylethanol) for Detection and Quantification of Alcohol Use in Youth Living with HIV
    UCSF AIDS Research Institute Jul 1, 2020 - Jun 30, 2022
    Role: Principal Investigator
    Description: The goal of this project is to determine predictors of PEth positivity and to establish PEth cut points for clinically relevant drinking patterns in youth (ages 15-24) living with HIV.

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Efficacy of alcohol reduction interventions among people with HIV as evaluated by self-report and a phosphatidylethanol (PEth) outcome: protocol for a systematic review and individual participant data meta-analysis. BMJ Open. 2023 06 06; 13(6):e070713. Kane JC, Allen I, Fatch R, Scheffler A, Emenyonu N, Puryear SB, Chirayil P, So-Armah K, Kahler CW, Magidson JF, Conroy AA, Edelman EJ, Woolf-King S, Parry C, Kiene SM, Chamie G, Adong J, Go VF, Cook RL, Muyindike W, Morojele N, Blokhina E, Krupitsky E, Fiellin DA, Hahn JA. PMID: 37280036; PMCID: PMC10254608.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Universal HIV Testing and Treatment with Patient-Centered Care Improves ART Uptake and Viral Suppression among Adults Reporting Hazardous Alcohol Use in Uganda and Kenya. J Acquir Immune Defic Syndr. 2023 May 22. Puryear SB, Ayieko J, Hahn JA, Mucunguzi A, Owaraganise A, Schwab J, Balzer LB, Kwarisiima D, Charlebois ED, Cohen CR, Bukusi EA, Petersen ML, Havlir DV, Kamya MR, Chamie G. PMID: 37220015.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Effects of a COVID-19 Public Health Lockdown on Drinking and Health Behavior Among Persons with HIV and with Unhealthy Alcohol use in Uganda. AIDS Behav. 2023 Mar 31. Beesiga B, Marson K, Fatch R, Emenyonu NI, Adong J, Kekibiina A, Puryear S, Lodi S, McDonell MG, Muyindike WR, Kamya MR, Hahn JA, Chamie G. PMID: 37000383; PMCID: PMC10063928.
      View in: PubMed   Mentions:    Fields:    
    4. Associations between alcohol and cigarette use and type 1 and 2 myocardial infarction among people with HIV. HIV Med. 2023 06; 24(6):703-715. Drumright LN, Nance RM, Ruderman SA, Ma J, Whitney BM, Hahn A, Fredericksen RJ, Luu B, Lober WB, Moore RD, Budoff MJ, Keruly JC, Christopoulos K, Puryear S, Willig A, Cropsey K, Mathews WC, Cachay E, Bamford L, Eron JJ, Napravnik S, Mayer KH, O'Cleirigh C, Mccaul ME, Chander G, Feinstein MJ, Saag MS, Kitahata MM, Heckbert SR, Crane HM, Delaney JAC. PMID: 36855253; PMCID: PMC10330202.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. ID Learning Unit: Understanding Advances in the Treatment of Latent Tuberculosis Infection among People with HIV. Open Forum Infectious Diseases. 2021; ofab319. Nicky J Mehtani, Sarah Puryear, Paul Pham, Kelly E Dooley, Maunank Shah. View Publication.
    6. Infectious Diseases Learning Unit: Understanding Advances in the Treatment of Latent Tuberculosis Infection Among People With Human Immunodeficiency Virus. Open Forum Infect Dis. 2021 Aug; 8(8):ofab319. Mehtani NJ, Puryear S, Pham P, Dooley KE, Shah M. PMID: 34395707; PMCID: PMC8361237.
      View in: PubMed   Mentions: 2  
    7. Higher Levels of Alcohol Use Are Associated With Latent Tuberculosis Infection in Adults Living With Human Immunodeficiency Virus. Clin Infect Dis. 2021 03 01; 72(5):865-868. Puryear SB, Fatch R, Beesiga B, Kekibiina A, Lodi S, Marson K, Emenyonu NI, Muyindike WR, Kwarisiima D, Hahn JA, Chamie G. PMID: 32374867; PMCID: PMC7935375.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    8. Associations between alcohol use and HIV care cascade outcomes among adults undergoing population-based HIV testing in East Africa. AIDS. 2020 03 01; 34(3):405-413. Puryear SB, Balzer LB, Ayieko J, Kwarisiima D, Hahn JA, Charlebois ED, Clark TD, Cohen CR, Bukusi EA, Kamya MR, Petersen ML, Havlir DV, Chamie G. PMID: 31725431; PMCID: PMC7046088.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    9. Disseminated Cutaneous and Osteoarticular Sporotrichosis Mimicking Pyoderma Gangrenosum. Open Forum Infect Dis. 2019 Oct; 6(10):ofz395. Saeed L, Weber RJ, Puryear SB, Bahrani E, Peluso MJ, Babik JM, Haemel A, Coates SJ. PMID: 31660357; PMCID: PMC6786506.
      View in: PubMed   Mentions: 4  
    10. HIV seroconversion among Baltimore City residents tested at a mobile van programme. Sex Transm Infect. 2018 02; 94(1):37-39. Puryear S, Burnett P, Page KR, Muvva R, Chaulk P, Ghanem KG, Monroe A. PMID: 28899995; PMCID: PMC7216789.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. High magnitude of under nutrition among HIV infected adults who have not started ART in Tanzania--a call to include nutrition care and treatment in the test and treat model. BMC Nutrition. 2017; 58(3). Bruno F. Sunguya, Nzovu K. Ulenga, Hellen Siril, Sarah Puryear, Eric Aris, Expeditho Mtisi, Edith Tarimo, David P. Urassa, Wafaie Fawzi & Ferdnand Mugusi . View Publication.
    12. High magnitude of under nutrition among HIV infected adults who have not started ART in Tanzania--a call to include nutrition care and treatment in the test and treat model. BMC Nutr. 2017; 3:58. Sunguya BF, Ulenga NK, Siril H, Puryear S, Aris E, Mtisi E, Tarimo E, Urassa DP, Fawzi W, Mugusi F. PMID: 32153838; PMCID: PMC7050693.
      View in: PubMed   Mentions: 2  
    13. Yield of contact tracing from pediatric tuberculosis index cases in Gaborone, Botswana. Int J Tuberc Lung Dis. 2013 Aug; 17(8):1049-55. Puryear S, Seropola G, Ho-Foster A, Arscott-Mills T, Mazhani L, Firth J, Goldfarb DM, Ncube R, Bisson GP, Steenhoff AP. PMID: 23827029; PMCID: PMC6219389.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansPHPublic Health
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