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LNK/SH2B3 as a novel driver in juvenile myelomonocytic leukemia. Haematologica. 2024 08 01; 109(8):2533-2541.
Wintering A, Hecht A, Meyer J, Wong EB, Hübner J, Abelson S, Feldman K, Kennedy VE, Peretz CAC, French DL, Maguire JA, Jobaliya C, Vasquez MR, Desai S, Dulman R, Nemecek E, Haines H, Hammad M, El Haddad A, Kogan SC, Abdullaev Z, Chehab FF, Tasian SK, Smith CC, Loh ML, Stieglitz E. PMID: 38152053; PMCID: PMC11290546.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Early-life tobacco exposure is causally implicated in aberrant RAG-mediated recombination in childhood acute lymphoblastic leukemia. Res Sq. 2024 Jun 20.
de Smith A, Liu T, Xu K, Pardeshi A, Myint SS, Kang A, Morimoto L, Lieber M, Wiemels J, Wiemels J, Kogan S, Metayer C. PMID: 38946984; PMCID: PMC11213169.
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Efficacy of the Allosteric MEK Inhibitor Trametinib in Relapsed and Refractory Juvenile Myelomonocytic Leukemia: a Report from the Children's Oncology Group. Cancer Discov. 2024 Jun 11; OF1-OF9.
Stieglitz E, Lee AG, Angus SP, Davis C, Barkauskas DA, Hall D, Kogan SC, Meyer J, Rhodes SD, Tasian SK, Xuei X, Shannon K, Loh ML, Fox E, Weigel BJ. PMID: 38867349.
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PubMed Mentions: Fields:
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Impact of pinworm infection on the development of murine B-cell leukemia/lymphoma in the presence and absence of ETV6::RUNX1. Haematologica. 2023 Dec 01; 108(12):3480-3484.
Fitch BA, Situ J, Wiemels JL, Wiemels JL, Kogan SC, Zhou M. PMID: 37345483; PMCID: PMC10690896.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Gene-Environment Analyses Reveal Novel Genetic Candidates with Prenatal Tobacco Exposure in Relation to Risk for Childhood Acute Lymphoblastic Leukemia. Cancer Epidemiol Biomarkers Prev. 2023 12 01; 32(12):1707-1715.
Zhong C, Li S, Arroyo K, Morimoto LM, de Smith AJ, Metayer C, Ma X, Kogan SC, Gauderman WJ, Wiemels JL, Wiemels JL. PMID: 37773025.
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PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
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Efficacy of the Allosteric MEK Inhibitor Trametinib in Relapsed and Refractory Juvenile Myelomonocytic Leukemia: A Report from the Children's Oncology Group. Blood. 2023 Nov 28; 142(Supplement 1):74.
Stieglitz SE, Lee LA, Angus AS, Davis DC, Barkauskas BD, Hall HD, Kogan KS, Meyer MJ, Rhodes RS, Xuei XX, Shannon SK, Loh LM, Fox FE, Weigel WB. .
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Genetic architecture of the acute and persistent immune cell response after radiation exposure. Cell Genom. 2023 Nov 08; 3(11):100422.
He L, Zhong C, Chang H, Inman JL, Celniker SE, Ioakeim-Ioannidou M, Liu KX, Haas-Kogan D, MacDonald SM, Threadgill DW, Kogan SC, Mao JH, Snijders AM. PMID: 38020972; PMCID: PMC10667298.
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PubMed Mentions: Fields:
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The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression. J Clin Invest. 2023 07 03; 133(13).
Mas G, Man N, Nakata Y, Martinez-Caja C, Karl D, Beckedorff F, Tamiro F, Chen C, Duffort S, Itonaga H, Mookhtiar AK, Kunkalla K, Valencia AM, Collings CK, Kadoch C, Vega F, Kogan SC, Shiekhattar R, Morey L, Bilbao D, Nimer SD. PMID: 37200093; PMCID: PMC10313367.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Dapsone-induced methemoglobinemia and hemolysis in a woman without G6PD deficiency presenting with idiopathic urticaria. Hematology. 2022 Dec; 27(1):1253-1258.
Hu Y, Geere M, Awan M, Leavitt AD, Brown LE, Pearson HJ, Gandelman JS, Kogan SC. PMID: 36444994; PMCID: PMC9788447.
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Translation:
Humans
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Cytomegalovirus proteins, maternal pregnancy cytokines, and their impact on neonatal immune cytokine profiles and acute lymphoblastic leukemogenesis in children. Haematologica. 2022 09 01; 107(9):2266-2270.
Wiemels JL, Wiemels JL, Wang R, Zhou M, Hansen H, Gallant R, Jung J, Mancuso N, De Smith AJ, Metayer C, Kogan SC, Ma X. PMID: 35638549; PMCID: PMC9425315.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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RASA2 ablation in T cells boosts antigen sensitivity and long-term function. Nature. 2022 09; 609(7925):174-182.
Carnevale J, Shifrut E, Kale N, Nyberg WA, Blaeschke F, Chen YY, Li Z, Bapat SP, Diolaiti ME, O'Leary P, Vedova S, Belk J, Daniel B, Roth TL, Bachl S, Anido AA, Prinzing B, Ibañez-Vega J, Lange S, Haydar D, Luetke-Eversloh M, Born-Bony M, Hegde B, Kogan S, Feuchtinger T, Okada H, Satpathy AT, Shannon K, Gottschalk S, Eyquem J, Krenciute G, Ashworth A, Marson A. PMID: 36002574; PMCID: PMC9433322.
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PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Genomic Features of Interstitial Deletions of Chromosome 9q in Acute Myeloid Leukemia. Cytogenet Genome Res. 2022; 162(3):119-123.
Qi Z, Wen KW, Ki A, Prakash S, Kogan S, Yu J. PMID: 35675801; PMCID: PMC9677869.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Apixaban Concentrations in Routine Clinical Care of Older Adults With Nonvalvular Atrial Fibrillation. JACC Adv. 2022 Jun; 1(2).
Thomas A, Fang MC, Kogan S, Hubbard CC, Friedman PN, Gong L, Klein TE, Nutescu EA, O'Brien TJ, Tuck M, Perera MA, Schwartz JB. PMID: 37961076; PMCID: PMC10643025.
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1
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Clinical characteristics of cytomegalovirus-positive pediatric acute lymphoblastic leukemia at diagnosis. Am J Hematol. 2022 06 01; 97(6):E198-E201.
Gallant RE, Arroyo K, Bracci PM, Li S, Metayer C, Kogan SC, Wendt GA, Francis SS, de Smith AJ, Wiemels JL, Wiemels JL. PMID: 35285969.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Decreased IL-10 accelerates B-cell leukemia/lymphoma in a mouse model of pediatric lymphoid leukemia. Blood Adv. 2022 01 08; 6(3):854-865.
Fitch BA, Zhou M, Situ J, Surianarayanan S, Reeves MQ, Hermiston ML, Wiemels JL, Wiemels JL, Kogan SC. PMID: 34727170; PMCID: PMC8945291.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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Preventing Bleeding With Direct-Acting Oral Anticoagulants. J Am Coll Cardiol. 2021 10 19; 78(16):e127.
Schwartz JB, Kogan SC, Fang MC. PMID: 34649705; PMCID: PMC10631742.
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1 Fields:
Translation:
Humans
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Nf1 and Sh2b3 mutations cooperate in vivo in a mouse model of juvenile myelomonocytic leukemia. Blood Adv. 2021 09 28; 5(18):3587-3591.
Morales CE, Stieglitz E, Kogan SC, Loh ML, Braun BS. PMID: 34464969; PMCID: PMC8945579.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Cytokine Levels at Birth in Children Who Developed Acute Lymphoblastic Leukemia. Cancer Epidemiol Biomarkers Prev. 2021 08; 30(8):1526-1535.
Whitehead TP, Wiemels JL, Wiemels JL, Zhou M, Kang AY, McCoy LS, Wang R, Fitch B, Petrick LM, Yano Y, Imani P, Rappaport SM, Dahl GV, Kogan SC, Ma X, Metayer C. PMID: 34078642; PMCID: PMC8338848.
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PubMed Mentions:
6 Fields:
Translation:
HumansPHPublic Health
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Epigenetic Biomarkers of Prenatal Tobacco Smoke Exposure Are Associated with Gene Deletions in Childhood Acute Lymphoblastic Leukemia. Cancer Epidemiol Biomarkers Prev. 2021 08; 30(8):1517-1525.
Xu K, Li S, Whitehead TP, Pandey P, Kang AY, Morimoto LM, Kogan SC, Metayer C, Wiemels JL, Wiemels JL, de Smith AJ. PMID: 34020997; PMCID: PMC8338876.
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PubMed Mentions:
5 Fields:
Translation:
HumansCellsPHPublic Health
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Anti-factor Xa activity assays of direct-acting oral anticoagulants during clinical care: An observational study. Res Pract Thromb Haemost. 2021 May; 5(4):e12528.
Sukumar S, Cabero M, Tiu S, Fang MC, Kogan SC, Schwartz JB. PMID: 34013157; PMCID: PMC8114026.
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PubMed Mentions:
1
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In utero and early-life exposure to thirdhand smoke causes profound changes to the immune system. Clin Sci (Lond). 2021 04 30; 135(8):1053-1063.
Snijders AM, Zhou M, Whitehead TP, Fitch B, Pandey P, Hechmer A, Huang A, Schick SF, de Smith AJ, Olshen AB, Metayer C, Mao JH, Wiemels JL, Wiemels JL, Kogan SC. PMID: 33851706; PMCID: PMC8086195.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsPHPublic Health
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PubMed Mentions:
16 Fields:
Translation:
Humans
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PML-RARα: changing myeloid networks. Blood. 2021 03 18; 137(11):1439-1440.
Kogan SC. PMID: 33734342.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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The Baf Subunit Dpf2 Regulates Resolution of Inflammation By Controlling Macrophage Differentiation Transcription Factor Networks. Blood. 2020 Nov 5; 136(Supplement 1):13-13.
Mas Martin MG, Man MN, Karl KD, Martinez MC, Duffort DS, Itonaga IH, Mookhtiar MA, Bilbao BD, Kunkalla KK, Valencia VA, Collings CC, Kadoch KC, Vega VF, Kogan KS, Nimer NS. .
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KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice. JCI Insight. 2020 11 05; 5(21).
Wong JC, Perez-Mancera PA, Huang TQ, Kim J, Grego-Bessa J, Del Pilar Alzamora M, Kogan SC, Sharir A, Keefe SH, Morales CE, Schanze D, Castel P, Hirose K, Huang GN, Zenker M, Sheppard D, Klein OD, Tuveson DA, Braun BS, Shannon K. PMID: 32990679; PMCID: PMC7710308.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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History of Early Childhood Infections and Acute Lymphoblastic Leukemia Risk Among Children in a US Integrated Health-Care System. Am J Epidemiol. 2020 10 01; 189(10):1076-1085.
Morimoto LM, Kwan ML, Deosaransingh K, Munneke JR, Kang AY, Quesenberry C, Kogan S, de Smith AJ, Metayer C, Wiemels JL, Wiemels JL. PMID: 32322901; PMCID: PMC7670873.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Human pediatric B-cell acute lymphoblastic leukemias can be classified as B-1 or B-2-like based on a minimal transcriptional signature. Exp Hematol. 2020 10; 90:65-71.e1.
Fitch B, Roy R, Geng H, Montecino-Rodriguez E, Bengtsson H, Gaillard C, Hiam K, Casero D, Olshen AB, Dorshkind K, Kogan SC. PMID: 32946981; PMCID: PMC7606616.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Abstract A105: Trends in acute lymphocytic leukemia (ALL) incidence in the US from 2000-2016. Cancer Epidemiology Biomarkers & Prevention. 2020 Jun 1; 29(6_Supplement_2):a105-a105.
Feng FQ, Vergara-Lluri VM, Muskens MI, McKean-Cowdin MR, Kogan KS, Brynes BR, de Smith dA, Wiemels WJ. .
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Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice. Blood. 2020 05 14; 135(20):1772-1782.
Zambetti NA, Firestone AJ, Remsberg JR, Huang BJ, Wong JC, Long AM, Predovic M, Suciu RM, Inguva A, Kogan SC, Haigis KM, Cravatt BF, Shannon K. PMID: 32219446; PMCID: PMC7225687.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Abstract A23: A second site KrasG12D mutation that impairs PI3K binding rescues embryonic lethality, abrogates myeloproliferative disease, and delays lung tumorigenesis. Molecular Cancer Research. 2020 May 1; 18(5_Supplement):a23-a23.
Wong WJ, Perez-Mancera PP, Kim KJ, Jen JK, Kogan KS, Firestone FA, Collisson CE, Tuveson TD, Shannon SK. .
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Loss of glucocorticoid receptor expression mediates in vivo dexamethasone resistance in T-cell acute lymphoblastic leukemia. Leukemia. 2020 08; 34(8):2025-2037.
Wandler AM, Huang BJ, Craig JW, Hayes K, Yan H, Meyer LK, Scacchetti A, Monsalve G, Dail M, Li Q, Wong JC, Weinberg O, Hasserjian RP, Kogan SC, Jonsson P, Yamamoto K, Sampath D, Nakitandwe J, Downing JR, Zhang J, Aster JC, Taylor BS, Shannon K. PMID: 32066867; PMCID: PMC7440098.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimals
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Increased neonatal level of arginase 2 in cases of childhood acute lymphoblastic leukemia implicates immunosuppression in the etiology. Haematologica. 2019 11; 104(11):e514-e516.
Nielsen AB, Zhou M, de Smith AJ, Wang R, McCoy L, Hansen H, Morimoto L, Grønbæk K, Johansen C, Kogan SC, Metayer C, Bracci PM, Ma X, Wiemels JL, Wiemels JL. PMID: 30923090; PMCID: PMC6821599.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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FLT3-ITD impedes retinoic acid, but not arsenic, responses in murine acute promyelocytic leukemias. Blood. 2019 03 28; 133(13):1495-1506.
Esnault C, Rahmé R, Rice KL, Berthier C, Gaillard C, Quentin S, Maubert AL, Kogan S, de Thé H. PMID: 30674471; PMCID: PMC6440296.
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PubMed Mentions:
24 Fields:
Translation:
Animals
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Identification of IRF8 as a potent tumor suppressor in murine acute promyelocytic leukemia. Blood Adv. 2018 10 09; 2(19):2462-2466.
Gaillard C, Surianarayanan S, Bentley T, Warr MR, Fitch B, Geng H, Passegué E, de Thé H, Kogan SC. PMID: 30266821; PMCID: PMC6177650.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
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Dilute Russell viper venom time interpretation and clinical correlation: A two-year retrospective institutional review. Int J Lab Hematol. 2019 Feb; 41(1):80-86.
Jacquot C, Wool GD, Kogan SC. PMID: 30194751.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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TCEA1 regulates the proliferative potential of mouse myeloid cells. Exp Cell Res. 2018 09 15; 370(2):551-560.
Yang T, Cui H, Wen M, Zuber J, Kogan SC, Wei G. PMID: 30009791; PMCID: PMC6816334.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Abstract 3241: Children with acute lymphoblastic leukemia have increased arginase 2 at birth, implicating immunosuppression in leukemogenesis. Epidemiology. 2018 Jul 1; 3241-3241.
Nielsen NA, Zhou ZM, Smith SA, McCoy ML, Hansen HH, Bracci BP, Morimoto ML, Kogan KS, Metayer MC, Ma MX, Wiemels WJ. .
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Severe Iron Metabolism Defects in Mice With Double Knockout of the Multicopper Ferroxidases Hephaestin and Ceruloplasmin. Cell Mol Gastroenterol Hepatol. 2018; 6(4):405-427.
Fuqua BK, Lu Y, Frazer DM, Darshan D, Wilkins SJ, Dunn L, Loguinov AV, Kogan SC, Matak P, Chen H, Dunaief JL, Vulpe CD, Anderson GJ. PMID: 30182051; PMCID: PMC6120670.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Age-Related Impaired Efficacy of Bone Marrow Cell Therapy for Myocardial Infarction Reflects a Decrease in B Lymphocytes. Mol Ther. 2018 07 05; 26(7):1685-1693.
An S, Wang X, Ruck MA, Rodriguez HJ, Kostyushev DS, Varga M, Luu E, Derakhshandeh R, Suchkov SV, Kogan SC, Hermiston ML, Springer ML. PMID: 29914756; PMCID: PMC6036225.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia. Nat Commun. 2018 05 24; 9(1):2047.
Lehmann-Che J, Bally C, Letouzé E, Berthier C, Yuan H, Jollivet F, Ades L, Cassinat B, Hirsch P, Pigneux A, Mozziconacci MJ, Kogan S, Fenaux P, de Thé H. PMID: 29795382; PMCID: PMC5967331.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
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Pml nuclear body disruption cooperates in APL pathogenesis and impairs DNA damage repair pathways in mice. Blood. 2018 02 08; 131(6):636-648.
Voisset E, Moravcsik E, Stratford EW, Jaye A, Palgrave CJ, Hills RK, Salomoni P, Kogan SC, Solomon E, Grimwade D. PMID: 29191918; PMCID: PMC5805489.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
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Acute myeloid leukemia with t(14;21) involving RUNX1 and SYNE2: A novel favorable-risk translocation? Cancer Genet. 2017 Oct; 216-217:74-78.
Foley N, Van Ziffle J, Yu J, Qi Z, Grenert JP, Yeh I, Bastian B, Kogan S, Mannis GN. PMID: 29025598.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia. Blood. 2017 03 23; 129(12):1680-1684.
Francis SS, Wallace AD, Wendt GA, Li L, Liu F, Riley LW, Kogan S, Walsh KM, de Smith AJ, Dahl GV, Ma X, Delwart E, Metayer C, Wiemels JL, Wiemels JL. PMID: 27979823; PMCID: PMC5364339.
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PubMed Mentions:
34 Fields:
Translation:
HumansPHPublic Health
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Resistant T-Cell Acute Lymphoblastic Leukemias That Emerge after In Vivo Treatment with Dexamethasone Frequently Down-Regulate Glucocorticoid Receptor Protein Expression. Blood. 2016 Dec 2; 128(22):753-753.
Wandler WA, Huang HB, Scacchetti SA, Craig CJ, Yan YH, Monsalve MG, Li LQ, Dail DM, Wong WJ, Nakitandwe NJ, Weinberg WO, Hasserjian HR, Kogan KS, Sampath SD, Downing DJ, Yamamoto YK, Taylor TB, Aster AJ, Zhang ZJ, Shannon SK. .
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Mechanism of IL-10 Protective Effect in Development of Childhood B Cell Acute Lymphoblastic Leukemia. Blood. 2016 Dec 2; 128(22):4075-4075.
Fitch FB, Hermiston HM, Wiemels WJ, Kogan KS. .
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Dilute Russell Viper Venom Time Interpretation and Clinical Correlation: A Two-Year Retrospective Institutional Review. Blood. 2016 Dec 2; 128(22):2609-2609.
Jacquot JC, Wool WG, Kogan KS. .
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Identification of IRF8 As a Potent Tumor Suppressor in Murine Acute Promyelocytic Leukemia. Blood. 2016 Dec 2; 128(22):1518-1518.
Surianarayanan SS, Gaillard GC, Bentley BT, Warr WM, Fitch FB, Geng GH, Passegue PE, de Thé dH, Kogan KS. .
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Pml Nuclear Body Disruption Cooperates in APL Pathogenesis, Impacting DNA Damage Repair Pathways. Blood. 2016 Dec 2; 128(22):742-742.
Voisset VE, Moravcsik ME, Stratford SE, Jaye JA, Palgrave PC, Hills HR, Salomoni SP, Kogan KS, Solomon SE, Grimwade GD. .
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Genetic Subtypes of Human Pediatric ALLs Show Gene Expression Differences That Parallel Those Observed in Mouse B1 and B2 Progenitors, Suggesting Divergent Developmental Origins. Blood. 2016 Dec 2; 128(22):1741-1741.
Kogan KS, Geng GH, Roy RR, Montecino-Rodriguez ME, Gaillard GC, Hiam HK, Bengtsson BH, Casero CD, Olshen OA, Dorshkind DK. .
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Co-operative leukemogenesis in acute myeloid leukemia and acute promyelocytic leukemia reveals C/EBPα as a common target of TRIB1 and PML/RARA. Haematologica. 2016 10; 101(10):1228-1236.
Keeshan K, Vieugué P, Chaudhury S, Rishi L, Gaillard C, Liang L, Garcia E, Nakamura T, Omidvar N, Kogan SC. PMID: 27390356; PMCID: PMC5046652.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia. Cancer Discov. 2016 05; 6(5):501-15.
Meyer SE, Qin T, Muench DE, Masuda K, Venkatasubramanian M, Orr E, Suarez L, Gore SD, Delwel R, Paietta E, Tallman MS, Fernandez H, Melnick A, Le Beau MM, Kogan S, Salomonis N, Figueroa ME, Grimes HL. PMID: 27016502; PMCID: PMC4861898.
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PubMed Mentions:
58 Fields:
Translation:
HumansAnimalsCells
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Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice. J Clin Invest. 2016 Jan; 126(1):404.
Chang T, Krisman K, Theobald EH, Xu J, Akutagawa J, Lauchle JO, Kogan S, Braun BS, Shannon K. PMID: 26727232; PMCID: PMC4701564.
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PubMed Mentions:
2 Fields:
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Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis. Elife. 2015 Jul 20; 4.
Wong JC, Weinfurtner KM, Alzamora Mdel P, Kogan SC, Burgess MR, Zhang Y, Nakitandwe J, Ma J, Cheng J, Chen SC, Ho TT, Flach J, Reynaud D, Passegué E, Downing JR, Shannon K. PMID: 26193121; PMCID: PMC4569895.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation. Haematologica. 2015 Aug; 100(8):1064-75.
Gaillard C, Tokuyasu TA, Rosen G, Sotzen J, Vitaliano-Prunier A, Roy R, Passegué E, de Thé H, Figueroa ME, Kogan SC. PMID: 26088929; PMCID: PMC5004423.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia. Nat Immunol. 2015 Jul; 16(7):766-774.
Swaminathan S, Klemm L, Park E, Papaemmanuil E, Ford A, Kweon SM, Trageser D, Hasselfeld B, Henke N, Mooster J, Geng H, Schwarz K, Kogan SC, Casellas R, Schatz DG, Lieber MR, Greaves MF, Müschen M. PMID: 25985233; PMCID: PMC4475638.
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PubMed Mentions:
106 Fields:
Translation:
HumansAnimalsCells
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Direct and indirect targeting of MYC to treat acute myeloid leukemia. Cancer Chemother Pharmacol. 2015 Jul; 76(1):35-46.
Brondfield S, Umesh S, Corella A, Zuber J, Rappaport AR, Gaillard C, Lowe SW, Goga A, Kogan SC. PMID: 25956709; PMCID: PMC4485702.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis. Nat Genet. 2015 May; 47(5):539-43.
Zhao Z, Chen CC, Rillahan CD, Shen R, Kitzing T, McNerney ME, Diaz-Flores E, Zuber J, Shannon K, Le Beau MM, Spector MS, Kogan SC, Lowe SW. PMID: 25822087; PMCID: PMC4414804.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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Preclinical Efficacy of MEK Inhibition in Nras Mutant Acute Myeloid Leukemia. Blood. 2014 Dec 6; 124(21):3753-3753.
Burgess BM, Hwang HE, Firestone FA, Huang HT, Xu XJ, Zuber ZJ, Bohin BN, Wen WT, Kogan KS, Haigis HK, Lowe LS, Shannon SK, Li LQ. .
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Aberrant Hematopoietic Stem Cell Function in Mice Haploinsufficient for a 2 Mb Deletion of Chromosome 5A3 Syntenic to a Region of Human 7q22 Frequently Deleted in Myelodysplastic Syndromes. Blood. 2014 Dec 6; 124(21):3247-3247.
Wong WJ, Weinfurtner WK, Alzamora AP, Kogan KS, Burgess BM, Zhang ZY, Nakitandwe NJ, Ma MJ, Cheng CJ, Chen CS, Flach FJ, Reynaud RD, Passegue PE, Downing DJ, Shannon SK. .
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Preclinical efficacy of MEK inhibition in Nras-mutant AML. Blood. 2014 Dec 18; 124(26):3947-55.
Burgess MR, Hwang E, Firestone AJ, Huang T, Xu J, Zuber J, Bohin N, Wen T, Kogan SC, Haigis KM, Sampath D, Lowe S, Shannon K, Li Q. PMID: 25361812; PMCID: PMC4271180.
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PubMed Mentions:
59 Fields:
Translation:
HumansAnimalsCells
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MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia. Cancer Cell. 2014 May 12; 25(5):652-65.
Chen C, Liu Y, Rappaport AR, Kitzing T, Schultz N, Zhao Z, Shroff AS, Dickins RA, Vakoc CR, Bradner JE, Stock W, LeBeau MM, Shannon KM, Kogan S, Zuber J, Lowe SW. PMID: 24794707; PMCID: PMC4206212.
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PubMed Mentions:
180 Fields:
Translation:
HumansAnimalsCells
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Crenolanib is a selective type I pan-FLT3 inhibitor. Proc Natl Acad Sci U S A. 2014 Apr 08; 111(14):5319-24.
Smith CC, Lasater EA, Lin KC, Wang Q, McCreery MQ, Stewart WK, Damon LE, Perl AE, Jeschke GR, Sugita M, Carroll M, Kogan SC, Kuriyan J, Shah NP. PMID: 24623852; PMCID: PMC3986131.
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PubMed Mentions:
102 Fields:
Translation:
HumansCells
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CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression. Cancer Res. 2014 Jan 15; 74(2):520-31.
Wang Y, Wen M, Kwon Y, Xu Y, Liu Y, Zhang P, He X, Wang Q, Huang Y, Jen KY, LaBarge MA, You L, Kogan SC, Gray JW, Mao JH, Wei G. PMID: 24305877; PMCID: PMC3934357.
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PubMed Mentions:
111 Fields:
Translation:
HumansAnimalsCells
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Disruption Of PML Nuclear Bodies Cooperates In The Pathogenesis Of Acute Promyelocytic Leukemia. Blood. 2013 Nov 15; 122(21):3721-3721.
Moravcsik ME, Joannides JM, Voisset VE, Stratford SE, Zeisig ZB, Morris MJ, Densham DR, Palgrave PC, Stamp SG, Nye NE, Hills HR, Salomoni SP, Eric So EC, Kogan KS, Solomon SE, Grimwade GD. .
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The Challenge Of Russell’s Viper Venom Time Interpretation For Lupus Anticoagulant Diagnosis: A Two-Year Retrospective Institutional Review. Blood. 2013 Nov 15; 122(21):1131-1131.
Wool WG, Kogan KS. .
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Pten loss in the bone marrow leads to G-CSF-mediated HSC mobilization. J Exp Med. 2013 Oct 21; 210(11):2337-49.
Tesio M, Oser GM, Baccelli I, Blanco-Bose W, Wu H, Göthert JR, Kogan SC, Trumpp A. PMID: 24127490; PMCID: PMC3804947.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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The histone demethylase PHF8 governs retinoic acid response in acute promyelocytic leukemia. Cancer Cell. 2013 Mar 18; 23(3):376-89.
Arteaga MF, Mikesch JH, Qiu J, Christensen J, Helin K, Kogan SC, Dong S, So CW. PMID: 23518351; PMCID: PMC6812572.
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PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
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Initially disadvantaged, TEL-AML1 cells expand and initiate leukemia in response to irradiation and cooperating mutations. Leukemia. 2013 Jul; 27(7):1570-3.
Li M, Jones L, Gaillard C, Binnewies M, Ochoa R, Garcia E, Lam V, Wei G, Yang W, Lobe C, Hermiston M, Passegué E, Kogan SC. PMID: 23443342; PMCID: PMC3715751.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice. J Clin Invest. 2013 Jan; 123(1):335-9.
Chang T, Krisman K, Theobald EH, Xu J, Akutagawa J, Lauchle JO, Kogan S, Braun BS, Shannon K. PMID: 23221337; PMCID: PMC3533281.
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PubMed Mentions:
69 Fields:
Translation:
HumansAnimals
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PML-RARa Deregulates an Unexpectedly Small Number of Genes in Pre-Leukemic Promyelocytes. Blood. 2012 Nov 16; 120(21):3526-3526.
Gaillard GC, Tokuyasu TT, Passegue´ PE, Kogan KS. .
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Evaluation of Patients with Bleeding Symptoms Using a Novel Perfusion Chamber Assay (PCA). Blood. 2012 Nov 16; 120(21):3295-3295.
Gorman GM, Kogan KS, Huang HJ, Stephens SG. .
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Crenolanib (CP-868,596) Is a Potent and Selective Type I FLT3 Inhibitor That Retains Activity Against AC220 Resistance-Causing FLT3 Kinase Domain Mutants. Blood. 2012 Nov 16; 120(21):141-141.
Smith SC, Lasater LE, Mccreery MM, Lin LK, Stewart SW, Damon DL, Perl PA, Jeschke JG, Sugita SM, Carroll CM, Kogan KS, Shah SN. .
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PML-RARα co-operates with Sox4 in acute myeloid leukemia development in mice. Haematologica. 2013 Mar; 98(3):424-7.
Omidvar N, Maunakea ML, Jones L, Sevcikova S, Yin B, Himmel KL, Tennant TR, Le Beau MM, Largaespada DA, Kogan SC. PMID: 23144197; PMCID: PMC3659942.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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A dominantly acting murine allele of Mcm4 causes chromosomal abnormalities and promotes tumorigenesis. PLoS Genet. 2012; 8(11):e1003034.
Bagley BN, Keane TM, Maklakova VI, Marshall JG, Lester RA, Cancel MM, Paulsen AR, Bendzick LE, Been RA, Kogan SC, Cormier RT, Kendziorski C, Adams DJ, Collier LS. PMID: 23133403; PMCID: PMC3486839.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Genetically mediated Nf1 loss in mice promotes diverse radiation-induced tumors modeling second malignant neoplasms. Cancer Res. 2012 Dec 15; 72(24):6425-34.
Choi G, Huang B, Pinarbasi E, Braunstein SE, Horvai AE, Kogan S, Bhatia S, Faddegon B, Nakamura JL. PMID: 23071067; PMCID: PMC3787120.
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PubMed Mentions:
16 Fields:
Translation:
Animals
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An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model. Blood. 2012 May 10; 119(19):4512-23.
Bergerson RJ, Collier LS, Sarver AL, Been RA, Lugthart S, Diers MD, Zuber J, Rappaport AR, Nixon MJ, Silverstein KA, Fan D, Lamblin AF, Wolff L, Kersey JH, Delwel R, Lowe SW, O'Sullivan MG, Kogan SC, Adams DJ, Largaespada DA. PMID: 22427200; PMCID: PMC3362364.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Heterozygous Germ Line Deletion of a 2Mb Interval in Mice That Models Loss of 7q22 in Human Myeloid Malignancies Results in Defective Hematopoietic Stem Cell Function Reminiscent of Premature Aging. Blood. 2011 Nov 18; 118(21):2340-2340.
Wong WJ, Weinfurtner WK, Zhang ZY, Alzamora AP, Hwang HE, Kogan KS, Shannon SK. .
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Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity. Genes Dev. 2011 Oct 15; 25(20):2125-36.
Chien Y, Scuoppo C, Wang X, Fang X, Balgley B, Bolden JE, Premsrirut P, Luo W, Chicas A, Lee CS, Kogan SC, Lowe SW. PMID: 21979375; PMCID: PMC3205583.
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PubMed Mentions:
467 Fields:
Translation:
HumansAnimalsCells
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PML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway. Autophagy. 2011 Oct; 7(10):1132-44.
Huang Y, Hou JK, Chen TT, Zhao XY, Yan ZW, Zhang J, Yang J, Kogan SC, Chen GQ. PMID: 21673516; PMCID: PMC3210306.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Abstract A37: A dominantly acting allele of murine Mcm4 causes chromosome instability and promotes leukemiogenesis. Cancer Genomics. 2011 Sep 15; a37-a37.
Bagley BB, Maklakova MV, Kendziorski KC, Adams AD, Collier CL, Marshall MJ, Lester LR, Cancel CM, Bendzick BL, Keane KT, Kogan KS, Sullivan SR, Cormier CR. .
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Donor myocardial infarction impairs the therapeutic potential of bone marrow cells by an interleukin-1-mediated inflammatory response. Sci Transl Med. 2011 Sep 14; 3(100):100ra90.
Wang X, Takagawa J, Lam VC, Haddad DJ, Tobler DL, Mok PY, Zhang Y, Clifford BT, Pinnamaneni K, Saini SA, Su R, Bartel MJ, Sievers RE, Carbone L, Kogan S, Yeghiazarians Y, Hermiston M, Springer ML. PMID: 21918107; PMCID: PMC3350804.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimals
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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature. 2011 Aug 03; 478(7370):524-8.
Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA, Magoon D, Qi J, Blatt K, Wunderlich M, Taylor MJ, Johns C, Chicas A, Mulloy JC, Kogan SC, Brown P, Valent P, Bradner JE, Lowe SW, Vakoc CR. PMID: 21814200; PMCID: PMC3328300.
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PubMed Mentions:
1061 Fields:
Translation:
HumansAnimalsCells
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An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance. Genes Dev. 2011 Aug 01; 25(15):1628-40.
Zuber J, Rappaport AR, Luo W, Wang E, Chen C, Vaseva AV, Shi J, Weissmueller S, Fellmann C, Fellman C, Taylor MJ, Weissenboeck M, Graeber TG, Kogan SC, Vakoc CR, Lowe SW. PMID: 21828272; PMCID: PMC3182026.
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PubMed Mentions:
165 Fields:
Translation:
Animals
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A rapid and scalable system for studying gene function in mice using conditional RNA interference. Cell. 2011 Apr 01; 145(1):145-58.
Premsrirut PK, Dow LE, Kim SY, Camiolo M, Malone CD, Miething C, Scuoppo C, Zuber J, Dickins RA, Kogan SC, Shroyer KR, Sordella R, Hannon GJ, Lowe SW. PMID: 21458673; PMCID: PMC3244080.
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PubMed Mentions:
193 Fields:
Translation:
AnimalsCells
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Treatment with 5-azacytidine accelerates acute promyelocytic leukemia leukemogenesis in a transgenic mouse model. Genes Cancer. 2011 Feb; 2(2):160-5.
Scaglioni PP, Cai LF, Majid SM, Yung TM, Socci ND, Kogan SC, Kopelovich L, Pandolfi PP. PMID: 21779489; PMCID: PMC3111249.
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PubMed Mentions:
1
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Dose-dependent effects of focal fractionated irradiation on secondary malignant neoplasms in Nf1 mutant mice. Cancer Res. 2011 Jan 01; 71(1):106-15.
Nakamura JL, Phong C, Pinarbasi E, Kogan SC, Vandenberg S, Horvai AE, Faddegon BA, Fiedler D, Shokat K, Houseman BT, Chao R, Pieper RO, Shannon K. PMID: 21199799; PMCID: PMC3077533.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus. Blood. 2011 Feb 10; 117(6):2022-32.
Li Q, Haigis KM, McDaniel A, Harding-Theobald E, Kogan SC, Akagi K, Wong JC, Braun BS, Wolff L, Jacks T, Shannon K. PMID: 21163920; PMCID: PMC3056645.
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PubMed Mentions:
84 Fields:
Translation:
HumansAnimalsCells
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Mutant BCL2 Co-Operates with CBFß/PEBP2ß-MYH11 to Promote Expansion of Leukemia Initiating Cells with a Predominantly Pro-Apoptotic Mechanism Via Recruitment of Ras-GTP In a Mouse Model of Progressive Acute Myeloid Leukemia. Blood. 2010 Nov 19; 116(21):1050-1050.
Omidvar ON, Pogam PC, Beurlet BS, Noguera NM, Janin JA, Kogan KS, Weissman WI, Pla PM, Chomienne CC, Padua PR. .
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ABT-737 Targets Leukemic Stem Cells In Mouse Models of Mutant NRASD12/hBCL-2- Mediated Acute Myeloid Leukemia Progression with Increased Survival. Blood. 2010 Nov 19; 116(21):3308-3308.
Padua PR, Beurlet BS, Krief KP, Omidvar ON, Pogam PC, Auboeuf AD, de la Grange dP, Soulie SA, Janin JA, Noguera NM, Merlet MP, Sarda-Mantel SL, Fenaux FP, Konopleva KM, Andreeff AM, Tu TA, Yang YP, Fan FA, Kogan KS, Weissman WI, Felsher FD, Pla PM, West WR, Chomienne CC. .
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Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia. J Exp Med. 2010 Nov 22; 207(12):2581-94.
Jones L, Wei G, Sevcikova S, Phan V, Jain S, Shieh A, Wong JC, Li M, Dubansky J, Maunakea ML, Ochoa R, Zhu G, Tennant TR, Shannon KM, Lowe SW, Le Beau MM, Kogan SC. PMID: 21059853; PMCID: PMC2989761.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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PML-RAR{alpha} and Dnmt3a1 cooperate in vivo to promote acute promyelocytic leukemia. Cancer Res. 2010 Nov 01; 70(21):8792-801.
Subramanyam D, Belair CD, Barry-Holson KQ, Lin H, Kogan SC, Passegué E, Blelloch R. PMID: 20861188; PMCID: PMC3021794.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal. Genes Dev. 2010 Jul 01; 24(13):1389-402.
Zhao Z, Zuber J, Diaz-Flores E, Lintault L, Kogan SC, Shannon K, Lowe SW. PMID: 20595231; PMCID: PMC2895198.
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PubMed Mentions:
97 Fields:
Translation:
AnimalsCells
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Abstract 3427A: Focal fractionated irradiation induces specific malignancies in a dose-dependent manner in Nf1 mutant mice. Clinical Research. 2010 Apr 15; 3427a-3427a.
Nakamura NJ, Phong PC, Pinarbasi PE, Kogan KS, Vandenberg VS, Horvai HA, Faddegon FB, Houseman HB, Pieper PR, Shannon SK. .
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Medicine. Poisonous contacts. Science. 2010 Apr 09; 328(5975):184-5.
Kogan SC. PMID: 20378808.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies. Blood. 2010 Jun 03; 115(22):4524-32.
Wong JC, Zhang Y, Lieuw KH, Tran MT, Forgo E, Weinfurtner K, Alzamora P, Kogan SC, Akagi K, Wolff L, Le Beau MM, Killeen N, Shannon K. PMID: 20233966; PMCID: PMC2881500.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents. Proc Natl Acad Sci U S A. 2010 Mar 16; 107(11):5106-11.
Dail M, Li Q, McDaniel A, Wong J, Akagi K, Huang B, Kang HC, Kogan SC, Shokat K, Wolff L, Braun BS, Shannon K. PMID: 20194733; PMCID: PMC2841878.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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An Insertional Mutagenesis Screen for Genes That Cooperate with Mll-AF9 in Leukemogenesis. Blood. 2009 Nov 20; 114(22):3962-3962.
Bergerson BR, Collier CL, Lugthart LS, Allaei AR, Nixon NM, Silverstein SK, Sarver SA, Fan FD, Lamblin LA, Wolff WL, Kersey KJ, O'Sullivan OM, Delwel DR, Kogan KS, Adams AD, Largaespada LD. .
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Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras. Nature. 2009 Sep 17; 461(7262):411-4.
Lauchle JO, Kim D, Le DT, Akagi K, Crone M, Krisman K, Warner K, Bonifas JM, Li Q, Coakley KM, Diaz-Flores E, Gorman M, Przybranowski S, Tran M, Kogan SC, Roose JP, Copeland NG, Jenkins NA, Parada L, Wolff L, Sebolt-Leopold J, Shannon K. PMID: 19727076; PMCID: PMC4119783.
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PubMed Mentions:
85 Fields:
Translation:
Animals
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Mouse models of human AML accurately predict chemotherapy response. Genes Dev. 2009 Apr 01; 23(7):877-89.
Zuber J, Radtke I, Pardee TS, Zhao Z, Rappaport AR, Luo W, McCurrach ME, Yang MM, Dolan ME, Kogan SC, Downing JR, Lowe SW. PMID: 19339691; PMCID: PMC2666344.
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PubMed Mentions:
162 Fields:
Translation:
HumansAnimals
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Curing APL: differentiation or destruction? Cancer Cell. 2009 Jan 06; 15(1):7-8.
Kogan SC. PMID: 19111876.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimals
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Myc Drives Chromosomal Gain in Acute Myeloid Leukemia. Blood. 2008 Nov 16; 112(11):792-792.
Jones JL, Sevcikova SS, Phan PV, Jain JS, Shieh SA, Dubansky DJ, Li LM, Maunakea MM, Zhu ZG, Tennant TT, Lowe LS, Le LM, Kogan KS. .
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ABT-737 Targets Intrinsic Apoptosis during Cooperation of BCL-2 and Oncogenic NRAS in An in Vivo Progression Model of Myelodysplasia/Acute Myeloid Leukaemia. Blood. 2008 Nov 16; 112(11):848-848.
Omidvar ON, Beurlet BS, Le Pogam LC, Janin JA, Leboeuf LC, Soulie SA, Setterblad SN, Noguera NM, Sarda-Mantel SL, Merlet MP, Pla PM, Kogan KS, Weissman WI, Konopleva KM, Bormann BW, Andreeff AM, Chomienne CC, Padua PR. .
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Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family. Cell Stem Cell. 2008 Oct 09; 3(4):416-28.
Viatour P, Somervaille TC, Venkatasubrahmanyam S, Kogan S, McLaughlin ME, Weissman IL, Butte AJ, Passegué E, Sage J. PMID: 18940733; PMCID: PMC2646421.
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PubMed Mentions:
95 Fields:
Translation:
AnimalsCells
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Fractionated Cranial Irradiation Induces a Distinctive Pattern of Second Malignant Neoplasms in Nf1 Mutant Mice. International Journal of Radiation Oncology • Biology • Physics. 2008 Sep 1; 72(1):s83.
Nakamura NJ, Phong PC, Kogan KS, Vandenberg VS, Pieper PR, Shannon SK. .
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mTORC1 promotes survival through translational control of Mcl-1. Proc Natl Acad Sci U S A. 2008 Aug 05; 105(31):10853-8.
Mills JR, Hippo Y, Robert F, Chen SM, Malina A, Lin CJ, Trojahn U, Wendel HG, Charest A, Bronson RT, Kogan SC, Nadon R, Housman DE, Lowe SW, Pelletier J. PMID: 18664580; PMCID: PMC2504845.
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PubMed Mentions:
166 Fields:
Translation:
AnimalsCells
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Survival and tumorigenesis in O6-methylguanine DNA methyltransferase-deficient mice following cyclophosphamide exposure. Mutagenesis. 2008 Sep; 23(5):341-6.
Nagasubramanian R, Hansen RJ, Delaney SM, Cherian MM, Samson LD, Kogan SC, Dolan ME. PMID: 18477655; PMCID: PMC2527341.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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The protective effect of KCNMB1 E65K against hypertension is restricted to blood pressure treatment with beta-blockade. J Hum Hypertens. 2008 Jul; 22(7):512-5.
Kelley-Hedgepeth A, Peter I, Kip K, Montefusco M, Kogan S, Cox D, Ordovas J, Levy D, Reis S, Mendelsohn M, Housman D, Huggins G. PMID: 18418400; PMCID: PMC2659689.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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BCL-2 and mutant NRAS interact physically and functionally in a mouse model of progressive myelodysplasia. Cancer Res. 2007 Dec 15; 67(24):11657-67.
Omidvar N, Kogan S, Beurlet S, le Pogam C, Janin A, West R, Noguera ME, Reboul M, Soulie A, Leboeuf C, Setterblad N, Felsher D, Lagasse E, Mohamedali A, Thomas NS, Fenaux P, Fontenay M, Pla M, Mufti GJ, Weissman I, Chomienne C, Padua RA. PMID: 18089795.
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PubMed Mentions:
27 Fields:
Translation:
Animals
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Novel Mll-AF9 Cooperating Genes Identified in a Leukemogenesis Screen Using Retroviral Mutagenesis. Blood. 2007 Nov 16; 110(11):825-825.
Bergerson BR, Collier CL, Allaei AR, Silverstein SK, Lamblin LA, Wolff WL, Kogan KS, Kersey KJ, Adams AD, Largaespada LD. .
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Expressing N-RasG12D from the Endogenous Promoter Induces Myeloproliferative Disease (MPD) and Cooperates with Retroviral Insertional Mutagenesis (RIM) To Generate Acute Myeloid Leukemia (AML). Blood. 2007 Nov 16; 110(11):1616-1616.
Li LQ, Haigis HK, McDaniel MA, Huang HB, Miller MM, Shieh SA, Kogan KS, Wolff WL, Jacks JT, Shannon SK. .
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PPARgamma-active triterpenoid CDDO enhances ATRA-induced differentiation in APL. Cancer Biol Ther. 2007 Dec; 6(12):1967-77.
Tabe Y, Konopleva M, Kondo Y, Contractor R, Tsao T, Konoplev S, Shi Y, Ling X, Watt JC, Tsutsumi-Ishii Y, Ohsaka A, Nagaoka I, Issa JP, Kogan SC, Andreeff M. PMID: 18075297.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders. Blood. 2007 Jul 15; 110(2):719-26.
Joslin JM, Fernald AA, Tennant TR, Davis EM, Kogan SC, Anastasi J, Crispino JD, Le Beau MM. PMID: 17420284; PMCID: PMC1924479.
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PubMed Mentions:
92 Fields:
Translation:
HumansAnimalsCells
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Mouse models of acute promyelocytic leukemia. Curr Top Microbiol Immunol. 2007; 313:3-29.
Kogan SC. PMID: 17217036.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimals
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Dual treatment with FLT3 inhibitor SU11657 and doxorubicin increases survival of leukemic mice. Leuk Res. 2007 Aug; 31(8):1131-4.
Lee BD, Sevcikova S, Kogan SC. PMID: 17184839; PMCID: PMC2680761.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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Acute Promyelocytic Leukemia Stem Cell Derived from Leukemic Progenitor. Blood. 2006 Nov 16; 108(11):235-235.
Rosen RG, Kogan KS. .
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SU11657 Cooperates with Doxorubicin To Increase Survival of Leukemic Mice. Blood. 2006 Nov 16; 108(11):4572-4572.
Sevcikova SS, Lee LB, Kogan KS. .
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Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice. Blood. 2007 Feb 15; 109(4):1687-91.
Kim A, Morgan K, Hasz DE, Wiesner SM, Lauchle JO, Geurts JL, Diers MD, Le DT, Kogan SC, Parada LF, Shannon K, Largaespada DA. PMID: 17090653; PMCID: PMC1794059.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo. Cancer Res. 2006 Aug 01; 66(15):7639-46.
Wendel HG, Malina A, Zhao Z, Zender L, Kogan SC, Cordon-Cardo C, Pelletier J, Lowe SW. PMID: 16885364; PMCID: PMC4586049.
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PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors. Cell. 2006 Jul 28; 126(2):415-26.
Forsberg EC, Serwold T, Kogan S, Weissman IL, Passegué E. PMID: 16873070.
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PubMed Mentions:
93 Fields:
Translation:
AnimalsCells
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CCAAT/enhancer binding proteins alpha and epsilon cooperate with all-trans retinoic acid in therapy but differ in their antileukemic activities. Blood. 2006 Oct 01; 108(7):2416-9.
Lee YJ, Jones LC, Timchenko NA, Perrotti D, Tenen DG, Kogan SC. PMID: 16788101; PMCID: PMC1895555.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Loss of p53 impedes the antileukemic response to BCR-ABL inhibition. Proc Natl Acad Sci U S A. 2006 May 09; 103(19):7444-9.
Wendel HG, de Stanchina E, Cepero E, Ray S, Emig M, Fridman JS, Veach DR, Bornmann WG, Clarkson B, McCombie WR, Kogan SC, Hochhaus A, Lowe SW. PMID: 16651519; PMCID: PMC1455409.
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PubMed Mentions:
53 Fields:
Translation:
HumansAnimalsCells
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Trp53 loss during in vitro selection contributes to acquired Ara-C resistance in acute myeloid leukemia. Exp Hematol. 2006 May; 34(5):631-41.
Yin B, Kogan SC, Dickins RA, Lowe SW, Largaespada DA. PMID: 16647569.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Leukemia with distinct phenotypes in transgenic mice expressing PML/RAR alpha, PLZF/RAR alpha or NPM/RAR alpha. Oncogene. 2006 Mar 23; 25(13):1974-9.
Rego EM, Ruggero D, Tribioli C, Cattoretti G, Kogan S, Redner RL, Pandolfi PP. PMID: 16331271.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimals
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Increased CCAAT enhancer-binding protein epsilon (C/EBPepsilon) expression and premature apoptosis in myeloid cells expressing Gfi-1 N382S mutant associated with severe congenital neutropenia. J Biol Chem. 2006 Apr 21; 281(16):10745-51.
Zhuang D, Qiu Y, Kogan SC, Dong F. PMID: 16500901.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Forced retinoic acid receptor alpha homodimers prime mice for APL-like leukemia. Cancer Cell. 2006 Feb; 9(2):81-94.
Sternsdorf T, Phan VT, Maunakea ML, Ocampo CB, Sohal J, Silletto A, Galimi F, Le Beau MM, Evans RM, Kogan SC. PMID: 16473276.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia. Cancer Cell. 2006 Jan; 9(1):57-68.
Kuo YH, Landrette SF, Heilman SA, Perrat PN, Garrett L, Liu PP, Le Beau MM, Kogan SC, Castilla LH. PMID: 16413472.
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78 Fields:
Translation:
AnimalsCells
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Investigation of Hematopoietic Stem Cell and Progenitor Populations: Implication for Cell Fate Determination and Lineage Commitment. Blood. 2005 Nov 16; 106(11):801-801.
Passegue PE, Forsberg FC, Serwold ST, Kogan KS, Weissman WI. .
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Haploinsufficiency of Runx1/AML1 promotes myeloid features and leukaemogenesis in BXH2 mice. Br J Haematol. 2005 Nov; 131(4):495-507.
Yamashita N, Osato M, Huang L, Yanagida M, Kogan SC, Iwasaki M, Nakamura T, Shigesada K, Asou N, Ito Y. PMID: 16281942.
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13 Fields:
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HumansAnimalsCells
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Opinion: how patients have benefited from mouse models of acute promyelocytic leukaemia. Nat Rev Cancer. 2005 10; 5(10):821-7.
Lallemand-Breitenbach V, Zhu J, Kogan S, Chen Z, de Thé H. PMID: 16175176.
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10 Fields:
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HumansAnimals
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Therapy-induced malignant neoplasms in Nf1 mutant mice. Cancer Cell. 2005 Oct; 8(4):337-48.
Chao RC, Pyzel U, Fridlyand J, Kuo YM, Teel L, Haaga J, Borowsky A, Horvai A, Kogan SC, Bonifas J, Huey B, Jacks TE, Albertson DG, Shannon KM. PMID: 16226708.
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19 Fields:
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AnimalsCells
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Induction of tumor arrest and differentiation with prolonged survival by intermittent hypoxia in a mouse model of acute myeloid leukemia. Blood. 2006 Jan 15; 107(2):698-707.
Liu W, Guo M, Xu YB, Li D, Zhou ZN, Wu YL, Chen Z, Kogan SC, Chen GQ. PMID: 16166593.
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21 Fields:
Translation:
AnimalsCells
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Role of O6-alkylguanine-DNA alkyltransferase in protecting against 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced long-term toxicities. J Pharmacol Exp Ther. 2005 Dec; 315(3):1247-55.
Hansen RJ, Nagasubramanian R, Delaney SM, Cherian MM, Lin S, Kogan SC, Dolan ME. PMID: 16126841.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Cooperation of Cytokine Signaling with Chimeric Transcription Factors in Leukemogenesis: PML-Retinoic Acid Receptor Alpha Blocks Growth Factor-Mediated Differentiation. Molecular and Cellular Biology. 2005 Jul 1; 25(13):5787-5787.
Phan PV, Shultz SD, Truong TB, Blake BT, Brown BA, Gonda GT, Le Beau LM, Kogan KS. .
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A sumoylation site in PML/RARA is essential for leukemic transformation. Cancer Cell. 2005 Feb; 7(2):143-53.
Zhu J, Zhou J, Peres L, Riaucoux F, Honoré N, Kogan S, de Thé H. PMID: 15710327.
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57 Fields:
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HumansAnimalsCells
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Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease. EMBO J. 2005 Jan 26; 24(2):368-81.
Wang J, Iwasaki H, Krivtsov A, Febbo PG, Thorner AR, Ernst P, Anastasiadou E, Kutok JL, Kogan SC, Zinkel SS, Fisher JK, Hess JL, Golub TR, Armstrong SA, Akashi K, Korsmeyer SJ. PMID: 15635450; PMCID: PMC545811.
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41 Fields:
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Animals
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O-14 A reversible two-step model ofMDS/preleukemia: Transgenic mice expressing inducible BCL2 and mutant NRAS. Leukemia Research. 2005 Jan 1; 29:s5.
Padua PR, Omidvar ON, Kogan KS, Phan PT, West WR, Felsher FD, Weissmann WI, Thomas TS, Whittaker WJ, Janin JA, Pla PM, Muftis MG, Bishop BJ, Chomienne CC. .
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Identification of Cooperating Genetic Alterations in RUNX Leukemia Using the Mouse Model for the Human Familial Leukemia, FPD/AML. Blood. 2004 Nov 16; 104(11):3383-3383.
Osato OM, Yamashita YN, Yanagida YM, Huang HL, Kogan KS, Iwasaki IM, Nakamura NT, Shigesada SK, Asou AN, Ito IY. .
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Cbfb-MYH11 Induces Expansion of a Lin-Kit+Sca1- Abnormal Progenitor Compartment that Predisposes Acute Myeloid Leukemia in Mice. Blood. 2004 Nov 16; 104(11):543-543.
Kuo KY, Heilman HS, Chen CA, Liu LP, Gernstein GR, Kogan KS, Castilla CL. .
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Increased DNA Damage and Error-Prone Repair in MPD/MDS Mice with Disease Progression: Key Indicators for Increased Genomic Instability. Blood. 2004 Nov 16; 104(11):200-200.
Rassool RF, Gaymes GT, Brady BN, Lea LN, Pla PM, Phan PT, Kogan KS, Chomienne CC, Thomas TN, Mafti MG, Padua PR. .
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Cooperative Pathways to Acute Myeloid Leukemia Include the Combining of Transcription Factor Alterations: PML-RARa Cooperates with SOX4. Blood. 2004 Nov 16; 104(11):3385-3385.
Kogan KS, Maunakea MM, Himmel HK, Yin YB, Le Beau LM, Largaespada LD. .
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Homodimerization of Retinoic Acid Receptor alpha through its Fusion Partners Underlies Pathogenesis of Acute Promyelocytic Leukemia. Blood. 2004 Nov 16; 104(11):546-546.
Kogan KS, Phan PV, Sternsdorf ST, Maunakea MM, Sohal SJ, Silletto SA, Galimi GF, Evans ER. .
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Discovery of Genes Involved in Experimental Pre-Leukemia to Leukemia Transition in Mice Using Expression Arrays. Blood. 2004 Nov 16; 104(11):1109-1109.
Entin EI, Kogan KS. .
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HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo. Blood. 2005 Feb 15; 105(4):1456-66.
Fischbach NA, Rozenfeld S, Shen W, Fong S, Chrobak D, Ginzinger D, Kogan SC, Radhakrishnan A, Le Beau MM, Largman C, Lawrence HJ. PMID: 15522959.
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49 Fields:
Translation:
AnimalsCells
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Myeloid Malignancies. Mouse Models of Human Cancer. 2004 Oct 15.
Kogan KS. .
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Mouse models of human cancers (part 3). Comp Med. 2004 Jun; 54(3):258-70.
Borowsky AD, Munn RJ, Galvez JJ, Cardiff RD, Ward JM, Morse HC, Kogan SC, Aldape KD, Louis DN, Bosenberg MW. PMID: 15253271.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy. Nature. 2004 Mar 18; 428(6980):332-7.
Wendel HG, De Stanchina E, Fridman JS, Malina A, Ray S, Kogan S, Cordon-Cardo C, Pelletier J, Lowe SW. PMID: 15029198.
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PubMed Mentions:
396 Fields:
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AnimalsCells
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Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder. Blood. 2004 Jun 01; 103(11):4243-50.
Le DT, Kong N, Zhu Y, Lauchle JO, Aiyigari A, Braun BS, Wang E, Kogan SC, Le Beau MM, Parada L, Shannon KM. PMID: 14982883.
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PubMed Mentions:
91 Fields:
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AnimalsCells
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The role of p53 in suppression of KSHV cyclin-induced lymphomagenesis. Cancer Res. 2004 Jan 15; 64(2):581-9.
Verschuren EW, Hodgson JG, Gray JW, Kogan S, Jones N, Evan GI. PMID: 14744772.
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30 Fields:
Translation:
AnimalsCells
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Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder. Proc Natl Acad Sci U S A. 2004 Jan 13; 101(2):597-602.
Braun BS, Tuveson DA, Kong N, Le DT, Kogan SC, Rozmus J, Le Beau MM, Jacks TE, Shannon KM. PMID: 14699048; PMCID: PMC327193.
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PubMed Mentions:
153 Fields:
Translation:
AnimalsCells
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PML-RARA-targeted DNA vaccine induces protective immunity in a mouse model of leukemia. Nat Med. 2003 Nov; 9(11):1413-7.
Padua RA, Larghero J, Robin M, le Pogam C, Schlageter MH, Muszlak S, Fric J, West R, Rousselot P, Phan TH, Mudde L, Teisserenc H, Carpentier AF, Kogan S, Degos L, Pla M, Bishop JM, Stevenson F, Charron D, Chomienne C. PMID: 14566333.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimals
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A PMLRARA transgene results in a retinoid-deficient phenotype associated with enhanced susceptibility to skin tumorigenesis. Cancer Res. 2003 Sep 01; 63(17):5257-65.
Hansen LA, Brown D, Virador V, Tanaka T, Andreola F, Strain K, Dancheck B, Riley R, Arbeit JM, De Luca LM, Kogan S, Yuspa SH. PMID: 14500356.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation. Mol Cell Biol. 2003 Jul; 23(13):4573-85.
Phan VT, Shultz DB, Truong BT, Blake TJ, Brown AL, Gonda TJ, Le Beau MM, Kogan SC. PMID: 12808098; PMCID: PMC164846.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice identify cooperating events and genetic pathways to acute promyelocytic leukemia. Blood. 2003 Aug 01; 102(3):1072-4.
Le Beau MM, Davis EM, Patel B, Phan VT, Sohal J, Kogan SC. PMID: 12689927.
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PubMed Mentions:
23 Fields:
Translation:
Animals
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A model of APL with FLT3 mutation is responsive to retinoic acid and a receptor tyrosine kinase inhibitor, SU11657. Blood. 2003 Apr 15; 101(8):3188-97.
Sohal J, Phan VT, Chan PV, Davis EM, Patel B, Kelly LM, Abrams TJ, O'Farrell AM, Gilliland DG, Le Beau MM, Kogan SC. PMID: 12515727.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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In vivo activation of cAMP signaling induces growth arrest and differentiation in acute promyelocytic leukemia. J Exp Med. 2002 Nov 18; 196(10):1373-80.
Guillemin MC, Raffoux E, Vitoux D, Kogan S, Soilihi H, Lallemand-Breitenbach V, Zhu J, Janin A, Daniel MT, Gourmel B, Degos L, Dombret H, Lanotte M, De Thé H. PMID: 12438428; PMCID: PMC2193985.
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28 Fields:
Translation:
AnimalsCells
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CCAAT/Enhancer binding proteins repress the leukemic phenotype of acute myeloid leukemia. Blood. 2003 Feb 01; 101(3):1141-8.
Truong BT, Lee YJ, Lodie TA, Park DJ, Perrotti D, Watanabe N, Koeffler HP, Nakajima H, Tenen DG, Kogan SC. PMID: 12393450.
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24 Fields:
Translation:
HumansAnimalsCells
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Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice. Blood. 2002 Jul 01; 100(1):238-45.
Kogan SC, Ward JM, Anver MR, Berman JJ, Brayton C, Cardiff RD, Carter JS, de Coronado S, Downing JR, Fredrickson TN, Haines DC, Harris AW, Harris NL, Hiai H, Jaffe ES, MacLennan IC, Pandolfi PP, Pattengale PK, Perkins AS, Simpson RM, Tuttle MS, Wong JF, Morse HC, Hematopathology subcommittee of the Mouse Models of Human Cancers Consortium. PMID: 12070033.
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PubMed Mentions:
227 Fields:
Translation:
HumansAnimals
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Bethesda proposals for classification of lymphoid neoplasms in mice. Blood. 2002 Jul 01; 100(1):246-58.
Morse HC, Anver MR, Fredrickson TN, Haines DC, Harris AW, Harris NL, Jaffe ES, Kogan SC, MacLennan IC, Pattengale PK, Ward JM, Hematopathology subcommittee of the Mouse Models of Human Cancers Consortium. PMID: 12070034.
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168 Fields:
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HumansAnimalsCells
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Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice parallel human acute promyelocytic leukemia. Blood. 2002 Apr 15; 99(8):2985-91.
Le Beau MM, Bitts S, Davis EM, Kogan SC. PMID: 11929790.
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34 Fields:
Translation:
HumansAnimalsCells
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Characteristics of consumer terminology for health information retrieval. Methods Inf Med. 2002; 41(4):289-98.
Zeng Q, Kogan S, Ash N, Greenes RA, Boxwala AA. PMID: 12425240.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Retroviral integration at the Epi1 locus cooperates with Nf1 gene loss in the progression to acute myeloid leukemia. J Virol. 2001 Oct; 75(19):9427-34.
Blaydes SM, Kogan SC, Truong BT, Gilbert DJ, Jenkins NA, Copeland NG, Largaespada DA, Brannan CI. PMID: 11533205; PMCID: PMC114510.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Mouse intestinal goblet cells expressing SV40 T antigen directed by the MUC2 mucin gene promoter undergo apoptosis upon migration to the villi. Cancer Res. 2001 Apr 15; 61(8):3472-9.
Gum JR, Hicks JW, Gillespie AM, Rius JL, Treseler PA, Kogan SC, Carlson EJ, Epstein CJ, Kim YS. PMID: 11309310.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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BCL-2 cooperates with promyelocytic leukemia retinoic acid receptor alpha chimeric protein (PMLRARalpha) to block neutrophil differentiation and initiate acute leukemia. J Exp Med. 2001 Feb 19; 193(4):531-43.
Kogan SC, Brown DE, Shultz DB, Truong BT, Lallemand-Breitenbach V, Guillemin MC, Lagasse E, Weissman IL, Bishop JM. PMID: 11181704; PMCID: PMC2195904.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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Patient and clinician vocabulary: how different are they? Stud Health Technol Inform. 2001; 84(Pt 1):399-403.
Zeng Q, Kogan S, Ash N, Greenes RA. PMID: 11604772.
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14 Fields:
Translation:
Humans
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Problems and challenges in patient information retrieval: a descriptive study. Proc AMIA Symp. 2001; 329-33.
Kogan S, Zeng Q, Ash N, Greenes RA. PMID: 11825205; PMCID: PMC2243602.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Acute promyelocytic leukemia: a view from a mouse. Blood Cells Mol Dis. 2000 Dec; 26(6):620-5.
Kogan SC. PMID: 11358354.
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2 Fields:
Translation:
HumansAnimals
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Leukemia initiated by PMLRARalpha: the PML domain plays a critical role while retinoic acid-mediated transactivation is dispensable. Blood. 2000 Mar 01; 95(5):1541-50.
Kogan SC, Hong SH, Shultz DB, Privalsky ML, Bishop JM. PMID: 10688806.
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30 Fields:
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HumansAnimalsCells
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Acute promyelocytic leukemia: from treatment to genetics and back. Oncogene. 1999 Sep 20; 18(38):5261-7.
Kogan SC, Bishop JM. PMID: 10498878.
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5 Fields:
Translation:
HumansAnimals
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Images in clinical medicine. Indinavir crystalluria. N Engl J Med. 1999 Apr 29; 340(17):1329.
Tsao JW, Kogan SC. PMID: 10219068.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia. J Exp Med. 1999 Apr 05; 189(7):1043-52.
Lallemand-Breitenbach V, Guillemin MC, Janin A, Daniel MT, Degos L, Kogan SC, Bishop JM, de Thé H. PMID: 10190895; PMCID: PMC2193002.
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PubMed Mentions:
82 Fields:
Translation:
HumansAnimalsCells
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The PEBP2betaMYH11 fusion created by Inv(16)(p13;q22) in myeloid leukemia impairs neutrophil maturation and contributes to granulocytic dysplasia. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11863-8.
Kogan SC, Lagasse E, Atwater S, Bae SC, Weissman I, Ito Y, Bishop JM. PMID: 9751756; PMCID: PMC21731.
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16 Fields:
Translation:
HumansAnimalsCells
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A PMLRARalpha transgene initiates murine acute promyelocytic leukemia. Proc Natl Acad Sci U S A. 1997 Mar 18; 94(6):2551-6.
Brown D, Kogan S, Lagasse E, Weissman I, Alcalay M, Pelicci PG, Atwater S, Bishop JM. PMID: 9122233; PMCID: PMC20126.
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PubMed Mentions:
125 Fields:
Translation:
HumansAnimalsCells
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6 The effect of fractionated radiotherapy in glioblastoma depends on P53 function. International Journal of Radiation Oncology • Biology • Physics. 1996 Jan 1; 36(1):161.
Haas-Kogan HD, Kogan KS, Yount YG, Hsu HJ, Dewey DW, Phillips PT, Israel IM. .
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Inhibition of apoptosis by the retinoblastoma gene product. EMBO J. 1995 Feb 01; 14(3):461-72.
Haas-Kogan DA, Kogan SC, Levi D, Dazin P, T'Ang A, Fung YK, Israel MA. PMID: 7859736; PMCID: PMC398104.
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PubMed Mentions:
48 Fields:
Translation:
HumansCells
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157 P53-dependent G1 arrest and P53-independent apoptosis influence the radiobiologic response of glioblastoma. International Journal of Radiation Oncology • Biology • Physics. 1995 Jan 1; 32:219.
Haas-Kogan HD, Yount YG, Haas HM, Levi LD, Kogan KS, Hu HL, Vidair VC, Deen DD, Dewey DW, Israel IM. .
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Genitourinary malformations associated with agenesis of the corpus callosum. J Urol. 1993 May; 149(5):1119-21.
Franco I, Kogan S, Fisher J, Rifkinson-Mann S, Reda E, Levitt S, Roseman B. PMID: 8483226.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Amino acid substitutions in conserved domains of factor VIII and related proteins: study of patients with mild and moderately severe hemophilia A. Hum Mutat. 1992; 1(3):248-57.
Diamond C, Kogan S, Levinson B, Gitschier J. PMID: 1301932.
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5 Fields:
Translation:
HumansCells
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Genetic basis of hemophilia A. Thromb Haemost. 1991 Jul 12; 66(1):37-9.
Gitschier J, Kogan S, Diamond C, Levinson B. PMID: 1926049.
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2 Fields:
Translation:
HumansCells
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Mutations and a polymorphism in the factor VIII gene discovered by denaturing gradient gel electrophoresis. Proc Natl Acad Sci U S A. 1990 Mar; 87(6):2092-6.
Kogan S, Gitschier J. PMID: 2107542; PMCID: PMC53632.
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20 Fields:
Translation:
HumansCells
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35 GENETIC PREDICTION OF HEMOPHILIA A. PCR Protocols. 1990 Jan 1; 288-299.
Kogan KS, Gitschier GJ. .
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Accurate prenatal diagnosis with novel polymerase chain reaction primers in a family with sporadic hemophilia A. Obstet Gynecol. 1989 Sep; 74(3 Pt 1):414-7.
Sarkar G, Evans MI, Kogan S, Lusher J, Sommer SS. PMID: 2569705.
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1 Fields:
Translation:
Humans
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Functional dissection and sequence of yeast HAP1 activator. Cell. 1989 Jan 27; 56(2):291-301.
Pfeifer K, Kim KS, Kogan S, Guarente L. PMID: 2643482.
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131 Fields:
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AnimalsCells
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Mutations of factor VIII cleavage sites in hemophilia A. Blood. 1988 Sep; 72(3):1022-8.
Gitschier J, Kogan S, Levinson B, Tuddenham EG. PMID: 3137981.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Mutations of factor VIII cleavage sites in hemophilia A. Blood. 1988 Sep 1; 72(3):1022-1028.
Gitschier GJ, Kogan KS, Levinson LB, Tuddenham TE. .
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An Improved Method for Prenatal Diagnosis of Genetic Diseases by Analysis of Amplified DNA Sequences. Obstetrical & Gynecological Survey. 1988 Apr 1; 43(4):236-238.
KOGAN KS, DOHERTY DM, GITSCHIER GJ. .
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An Improved Method for Prenatal Diagnosis of Genetic Diseases by Analysis of Amplified DNA Sequences. Obstetrical & Gynecological Survey. 1988 Apr 1; 43(4):236-238.
KOGAN KS, DOHERTY DM, GITSCHIER GJ. .
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An improved method for prenatal diagnosis of genetic diseases by analysis of amplified DNA sequences. Application to hemophilia A. N Engl J Med. 1987 Oct 15; 317(16):985-90.
Kogan SC, Doherty M, Gitschier J. PMID: 3657865.
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PubMed Mentions:
211 Fields:
Translation:
HumansCells