Scott Kogan, MD

Title(s)Professor, Laboratory Medicine
SchoolSchool of Medicine
AddressLocation Required
Varies CA 00000
ORCID ORCID Icon0000-0002-2395-8479 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Francisco, CAM.D.1991 School of Medicine
    University of California, San Francisco, CA Residency 1994School of Medicine
    University of California, San Francisco, CA10/2020Diversity, Equity, and Inclusion Champion Training

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Impact of low IL-10 levels at birth and leukemia risk
    NIH R01CA185058Jun 1, 2014 - May 31, 2020
    Role: Co-Principal Investigator
    Impact of B-Cell Lineage on Progression of B-Acute Lymphoblastic Leukemia
    NIH R21CA173028Feb 1, 2013 - Jan 31, 2016
    Role: Co-Principal Investigator
    Center for Integrative Research on Childhood Leukemia and the Environment
    NIH P50ES018172Sep 25, 2009 - Jun 30, 2019
    Role: Co-Investigator
    Molecular Mechanisms of Leukemogenesis by PMLRAR alpha
    NIH R01CA095274Apr 1, 2002 - Jan 31, 2014
    Role: Principal Investigator
    NIH K08CA075986Feb 19, 1999 - Jan 31, 2004
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cytokine levels at birth in children who developed acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev. 2021 Jun 02. Whitehead TP, Wiemels JL, Zhou M, Kang AY, McCoy LS, Wang R, Fitch B, Petrick LM, Yano Y, Imani P, Rappaport SM, Dahl GV, Kogan SC, Ma X, Metayer C. PMID: 34078642.
      View in: PubMed   Mentions:    Fields:    
    2. Epigenetic biomarkers of prenatal tobacco smoke exposure are associated with gene deletions in childhood acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev. 2021 May 21. Xu K, Li S, Whitehead TP, Pandey P, Kang AY, Morimoto LM, Kogan SC, Metayer C, Wiemels JL, de Smith AJ. PMID: 34020997.
      View in: PubMed   Mentions:    Fields:    
    3. Anti-factor Xa activity assays of direct-acting oral anticoagulants during clinical care: An observational study. Res Pract Thromb Haemost. 2021 May; 5(4):e12528. Sukumar S, Cabero M, Tiu S, Fang MC, Kogan SC, Schwartz JB. PMID: 34013157.
      View in: PubMed   Mentions:
    4. In utero and early-life exposure to thirdhand smoke causes profound changes to the immune system. Clin Sci (Lond). 2021 Apr 30; 135(8):1053-1063. Snijders AM, Zhou M, Whitehead TP, Fitch B, Pandey P, Hechmer A, Huang A, Schick SF, de Smith AJ, Olshen AB, Metayer C, Mao JH, Wiemels JL, Kogan SC. PMID: 33851706.
      View in: PubMed   Mentions:    Fields:    
    5. Trends in Acute Lymphoblastic Leukemia Incidence in the United States by Race/Ethnicity From 2000 to 2016. Am J Epidemiol. 2021 04 06; 190(4):519-527. Feng Q, de Smith AJ, Vergara-Lluri M, Muskens IS, McKean-Cowdin R, Kogan S, Brynes R, Wiemels JL. PMID: 33034340.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. PML-RARa: changing myeloid networks. Blood. 2021 Mar 18; 137(11):1439-1440. Kogan SC. PMID: 33734342.
      View in: PubMed   Mentions:    Fields:    
    7. The Baf Subunit Dpf2 Regulates Resolution of Inflammation By Controlling Macrophage Differentiation Transcription Factor Networks. Blood. 2020 Nov 5; 136(Supplement 1):13-13. Gloria Mas Martin, Na Man, Daniel Karl, Concepcion Martinez, Stephanie Duffort, Hidehiro Itonaga, Adnan K Mookhtiar, Daniel Bilbao, Kranthi Kunkalla, Alfredo M Valencia, Clayton Collings, Cigall Kadoch, Francisco Vega, Scott C. Kogan, Stephen Nimer. .
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    8. KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice. JCI Insight. 2020 11 05; 5(21). Wong JC, Perez-Mancera PA, Huang TQ, Kim J, Grego-Bessa J, Del Pilar Alzamora M, Kogan SC, Sharir A, Keefe SH, Morales CE, Schanze D, Castel P, Hirose K, Huang GN, Zenker M, Sheppard D, Klein OD, Tuveson DA, Braun BS, Shannon K. PMID: 32990679.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    9. History of Early Childhood Infections and Acute Lymphoblastic Leukemia Risk Among Children in a US Integrated Health-Care System. Am J Epidemiol. 2020 10 01; 189(10):1076-1085. Morimoto LM, Kwan ML, Deosaransingh K, Munneke JR, Kang AY, Quesenberry C, Kogan S, de Smith AJ, Metayer C, Wiemels JL. PMID: 32322901.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Human pediatric B-cell acute lymphoblastic leukemias can be classified as B-1 or B-2-like based on a minimal transcriptional signature. Exp Hematol. 2020 10; 90:65-71.e1. Fitch B, Roy R, Geng H, Montecino-Rodriguez E, Bengtsson H, Gaillard C, Hiam K, Casero D, Olshen AB, Dorshkind K, Kogan SC. PMID: 32946981.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    11. Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice. Blood. 2020 05 14; 135(20):1772-1782. Zambetti NA, Firestone AJ, Remsberg JR, Huang BJ, Wong JC, Long AM, Predovic M, Suciu RM, Inguva A, Kogan SC, Haigis KM, Cravatt BF, Shannon K. PMID: 32219446.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    12. Loss of glucocorticoid receptor expression mediates in vivo dexamethasone resistance in T-cell acute lymphoblastic leukemia. Leukemia. 2020 08; 34(8):2025-2037. Wandler AM, Huang BJ, Craig JW, Hayes K, Yan H, Meyer LK, Scacchetti A, Monsalve G, Dail M, Li Q, Wong JC, Weinberg O, Hasserjian RP, Kogan SC, Jonsson P, Yamamoto K, Sampath D, Nakitandwe J, Downing JR, Zhang J, Aster JC, Taylor BS, Shannon K. PMID: 32066867.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    13. Increased neonatal level of arginase 2 in cases of childhood acute lymphoblastic leukemia implicates immunosuppression in the etiology. Haematologica. 2019 11; 104(11):e514-e516. Nielsen AB, Zhou M, de Smith AJ, Wang R, McCoy L, Hansen H, Morimoto L, Grønbæk K, Johansen C, Kogan SC, Metayer C, Bracci PM, Ma X, Wiemels JL. PMID: 30923090.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. FLT3-ITD impedes retinoic acid, but not arsenic, responses in murine acute promyelocytic leukemias. Blood. 2019 03 28; 133(13):1495-1506. Esnault C, Rahmé R, Rice KL, Berthier C, Gaillard C, Quentin S, Maubert AL, Kogan S, de Thé H. PMID: 30674471.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    15. Identification of IRF8 as a potent tumor suppressor in murine acute promyelocytic leukemia. Blood Adv. 2018 10 09; 2(19):2462-2466. Gaillard C, Surianarayanan S, Bentley T, Warr MR, Fitch B, Geng H, Passegué E, de Thé H, Kogan SC. PMID: 30266821.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    16. Dilute Russell viper venom time interpretation and clinical correlation: A two-year retrospective institutional review. Int J Lab Hematol. 2019 Feb; 41(1):80-86. Jacquot C, Wool GD, Kogan SC. PMID: 30194751.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. TCEA1 regulates the proliferative potential of mouse myeloid cells. Exp Cell Res. 2018 09 15; 370(2):551-560. Yang T, Cui H, Wen M, Zuber J, Kogan SC, Wei G. PMID: 30009791.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    18. Severe Iron Metabolism Defects in Mice With Double Knockout of the Multicopper Ferroxidases Hephaestin and Ceruloplasmin. Cell Mol Gastroenterol Hepatol. 2018; 6(4):405-427. Fuqua BK, Lu Y, Frazer DM, Darshan D, Wilkins SJ, Dunn L, Loguinov AV, Kogan SC, Matak P, Chen H, Dunaief JL, Vulpe CD, Anderson GJ. PMID: 30182051.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    19. Age-Related Impaired Efficacy of Bone Marrow Cell Therapy for Myocardial Infarction Reflects a Decrease in B Lymphocytes. Mol Ther. 2018 07 05; 26(7):1685-1693. An S, Wang X, Ruck MA, Rodriguez HJ, Kostyushev DS, Varga M, Luu E, Derakhshandeh R, Suchkov SV, Kogan SC, Hermiston ML, Springer ML. PMID: 29914756.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    20. Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia. Nat Commun. 2018 05 24; 9(1):2047. Lehmann-Che J, Bally C, Letouzé E, Berthier C, Yuan H, Jollivet F, Ades L, Cassinat B, Hirsch P, Pigneux A, Mozziconacci MJ, Kogan S, Fenaux P, de Thé H. PMID: 29795382.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    21. Pml nuclear body disruption cooperates in APL pathogenesis and impairs DNA damage repair pathways in mice. Blood. 2018 02 08; 131(6):636-648. Voisset E, Moravcsik E, Stratford EW, Jaye A, Palgrave CJ, Hills RK, Salomoni P, Kogan SC, Solomon E, Grimwade D. PMID: 29191918.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    22. Acute myeloid leukemia with t(14;21) involving RUNX1 and SYNE2: A novel favorable-risk translocation? Cancer Genet. 2017 Oct; 216-217:74-78. Foley N, Van Ziffle J, Yu J, Qi Z, Grenert JP, Yeh I, Bastian B, Kogan S, Mannis GN. PMID: 29025598.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    23. In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia. Blood. 2017 03 23; 129(12):1680-1684. Francis SS, Wallace AD, Wendt GA, Li L, Liu F, Riley LW, Kogan S, Walsh KM, de Smith AJ, Dahl GV, Ma X, Delwart E, Metayer C, Wiemels JL. PMID: 27979823.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansPHPublic Health
    24. Identification of IRF8 As a Potent Tumor Suppressor in Murine Acute Promyelocytic Leukemia. Blood. 2016 Dec 2; 128(22):1518-1518. Sangeetha Surianarayanan, Coline M Gaillard, Trevor Bentley, Matthew R. Warr, Briana Fitch, Huimin Geng, Emmanuelle Passegue, Hugues de Thé, Scott C. Kogan. .
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    25. Genetic Subtypes of Human Pediatric ALLs Show Gene Expression Differences That Parallel Those Observed in Mouse B1 and B2 Progenitors, Suggesting Divergent Developmental Origins. Blood. 2016 Dec 2; 128(22):1741-1741. Scott C. Kogan, Huimin Geng, Ritu Roy, Encarnacion Montecino-Rodriguez, Coline M Gaillard, Kamir Hiam, Henrik Bengtsson, David Casero, Adam B Olshen, Kenneth Dorshkind. .
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    26. Pml Nuclear Body Disruption Cooperates in APL Pathogenesis, Impacting DNA Damage Repair Pathways. Blood. 2016 Dec 2; 128(22):742-742. Edwige Voisset, Eva Moravcsik, Eva W Stratford, Amie Jaye, Christopher J Palgrave, Robert K Hills, Paolo Salomoni, Scott C. Kogan, Ellen Solomon, David Grimwade. .
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    27. Resistant T-Cell Acute Lymphoblastic Leukemias That Emerge after In Vivo Treatment with Dexamethasone Frequently Down-Regulate Glucocorticoid Receptor Protein Expression. Blood. 2016 Dec 2; 128(22):753-753. Anica M. Wandler, Benjamin Huang, Alessandro Scacchetti, Jeff Craig, Hannah Yan, Gabriela Monsalve, Qing Li, Monique Dail, Jasmine C. Wong, Joy Nakitandwe, Olga Weinberg, Robert P. Hasserjian, Scott C. Kogan, Deepak Sampath, James R. Downing, Keith Yamamoto, Barry S. Taylor, Jon C. Aster, Jinghui Zhang, Kevin Shannon. .
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    28. Mechanism of IL-10 Protective Effect in Development of Childhood B Cell Acute Lymphoblastic Leukemia. Blood. 2016 Dec 2; 128(22):4075-4075. Briana Fitch, Michelle L. Hermiston, Joseph L. Wiemels, Scott C. Kogan. .
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    29. Dilute Russell Viper Venom Time Interpretation and Clinical Correlation: A Two-Year Retrospective Institutional Review. Blood. 2016 Dec 2; 128(22):2609-2609. Cyril Jacquot, Geoffrey D. Wool, Scott C. Kogan. .
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    30. Co-operative leukemogenesis in acute myeloid leukemia and acute promyelocytic leukemia reveals C/EBPa as a common target of TRIB1 and PML/RARA. Haematologica. 2016 10; 101(10):1228-1236. Keeshan K, Vieugué P, Chaudhury S, Rishi L, Gaillard C, Liang L, Garcia E, Nakamura T, Omidvar N, Kogan SC. PMID: 27390356.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    31. DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia. Cancer Discov. 2016 05; 6(5):501-15. Meyer SE, Qin T, Muench DE, Masuda K, Venkatasubramanian M, Orr E, Suarez L, Gore SD, Delwel R, Paietta E, Tallman MS, Fernandez H, Melnick A, Le Beau MM, Kogan S, Salomonis N, Figueroa ME, Grimes HL. PMID: 27016502.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    32. Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice. J Clin Invest. 2016 Jan; 126(1):404. Chang T, Krisman K, Theobald EH, Xu J, Akutagawa J, Lauchle JO, Kogan S, Braun BS, Shannon K. PMID: 26727232.
      View in: PubMed   Mentions: 1     Fields:    
    33. Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis. Elife. 2015 Jul 20; 4. Wong JC, Weinfurtner KM, Alzamora Mdel P, Kogan SC, Burgess MR, Zhang Y, Nakitandwe J, Ma J, Cheng J, Chen SC, Ho TT, Flach J, Reynaud D, Passegué E, Downing JR, Shannon K. PMID: 26193121.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    34. Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation. Haematologica. 2015 Aug; 100(8):1064-75. Gaillard C, Tokuyasu TA, Rosen G, Sotzen J, Vitaliano-Prunier A, Roy R, Passegué E, de Thé H, Figueroa ME, Kogan SC. PMID: 26088929.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    35. Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia. Nat Immunol. 2015 Jul; 16(7):766-774. Swaminathan S, Klemm L, Park E, Papaemmanuil E, Ford A, Kweon SM, Trageser D, Hasselfeld B, Henke N, Mooster J, Geng H, Schwarz K, Kogan SC, Casellas R, Schatz DG, Lieber MR, Greaves MF, Müschen M. PMID: 25985233.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    36. Direct and indirect targeting of MYC to treat acute myeloid leukemia. Cancer Chemother Pharmacol. 2015 Jul; 76(1):35-46. Brondfield S, Umesh S, Corella A, Zuber J, Rappaport AR, Gaillard C, Lowe SW, Goga A, Kogan SC. PMID: 25956709.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    37. Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis. Nat Genet. 2015 May; 47(5):539-43. Zhao Z, Chen CC, Rillahan CD, Shen R, Kitzing T, McNerney ME, Diaz-Flores E, Zuber J, Shannon K, Le Beau MM, Spector MS, Kogan SC, Lowe SW. PMID: 25822087.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    38. Aberrant Hematopoietic Stem Cell Function in Mice Haploinsufficient for a 2 Mb Deletion of Chromosome 5A3 Syntenic to a Region of Human 7q22 Frequently Deleted in Myelodysplastic Syndromes. Blood. 2014 Dec 6; 124(21):3247-3247. Jasmine C. Wong, Kelley Weinfurtner, Pilar Alzamora, Scott C. Kogan, Michael R. Burgess, Yan Zhang, Joy Nakitandwe, Jing Ma, Jinjun Cheng, Shann-Ching Chen, Johanna Flach, Damien Reynaud, Emmanuelle Passegue, James R Downing, Kevin Shannon. .
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    39. Preclinical Efficacy of MEK Inhibition in Nras Mutant Acute Myeloid Leukemia. Blood. 2014 Dec 6; 124(21):3753-3753. Michael R. Burgess, Eugene Hwang, Ari J Firestone, Tannie Huang, Jin Xu, Johannes Zuber, Natacha Bohin, Tiffany Wen, Scott C. Kogan, Kevin M. Haigis, Scott W. Lowe, Kevin Shannon, Qing Li. .
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    40. Preclinical efficacy of MEK inhibition in Nras-mutant AML. Blood. 2014 Dec 18; 124(26):3947-55. Burgess MR, Hwang E, Firestone AJ, Huang T, Xu J, Zuber J, Bohin N, Wen T, Kogan SC, Haigis KM, Sampath D, Lowe S, Shannon K, Li Q. PMID: 25361812.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    41. MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia. Cancer Cell. 2014 May 12; 25(5):652-65. Chen C, Liu Y, Rappaport AR, Kitzing T, Schultz N, Zhao Z, Shroff AS, Dickins RA, Vakoc CR, Bradner JE, Stock W, LeBeau MM, Shannon KM, Kogan S, Zuber J, Lowe SW. PMID: 24794707.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansAnimalsCells
    42. Crenolanib is a selective type I pan-FLT3 inhibitor. Proc Natl Acad Sci U S A. 2014 Apr 08; 111(14):5319-24. Smith CC, Lasater EA, Lin KC, Wang Q, McCreery MQ, Stewart WK, Damon LE, Perl AE, Jeschke GR, Sugita M, Carroll M, Kogan SC, Kuriyan J, Shah NP. PMID: 24623852.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    43. CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression. Cancer Res. 2014 Jan 15; 74(2):520-31. Wang Y, Wen M, Kwon Y, Xu Y, Liu Y, Zhang P, He X, Wang Q, Huang Y, Jen KY, LaBarge MA, You L, Kogan SC, Gray JW, Mao JH, Wei G. PMID: 24305877.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansAnimalsCells
    44. The Challenge Of Russell’s Viper Venom Time Interpretation For Lupus Anticoagulant Diagnosis: A Two-Year Retrospective Institutional Review. Blood. 2013 Nov 15; 122(21):1131-1131. Geoffrey D. Wool, Scott C. Kogan. .
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    45. Disruption Of PML Nuclear Bodies Cooperates In The Pathogenesis Of Acute Promyelocytic Leukemia. Blood. 2013 Nov 15; 122(21):3721-3721. Eva Moravcsik, Melanie Joannides, Edwige Voisset, Eva Wessel Stratford, Bernd B. Zeisig, Jo Morris, Ruth Densham, Chris Palgrave, Gordon Stamp, Emma Nye, Robert K. Hills, Paolo Salomoni, Chi Wai Eric So, Scott C. Kogan, Ellen Solomon, David Grimwade. .
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    46. Pten loss in the bone marrow leads to G-CSF-mediated HSC mobilization. J Exp Med. 2013 Oct 21; 210(11):2337-49. Tesio M, Oser GM, Baccelli I, Blanco-Bose W, Wu H, Göthert JR, Kogan SC, Trumpp A. PMID: 24127490.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    47. The histone demethylase PHF8 governs retinoic acid response in acute promyelocytic leukemia. Cancer Cell. 2013 Mar 18; 23(3):376-89. Arteaga MF, Mikesch JH, Qiu J, Christensen J, Helin K, Kogan SC, Dong S, So CW. PMID: 23518351.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    48. Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice. J Clin Invest. 2013 Jan; 123(1):335-9. Chang T, Krisman K, Theobald EH, Xu J, Akutagawa J, Lauchle JO, Kogan S, Braun BS, Shannon K. PMID: 23221337.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimals
    49. Evaluation of Patients with Bleeding Symptoms Using a Novel Perfusion Chamber Assay (PCA). Blood. 2012 Nov 16; 120(21):3295-3295. Matthew F. Gorman, Scott C. Kogan, James Huang, Gillian Stephens. .
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    50. PML-RARa Deregulates an Unexpectedly Small Number of Genes in Pre-Leukemic Promyelocytes. Blood. 2012 Nov 16; 120(21):3526-3526. Coline M Gaillard, Taku A Tokuyasu, Emmanuelle Passegue´, Scott C. Kogan. .
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    51. Crenolanib (CP-868,596) Is a Potent and Selective Type I FLT3 Inhibitor That Retains Activity Against AC220 Resistance-Causing FLT3 Kinase Domain Mutants. Blood. 2012 Nov 16; 120(21):141-141. Catherine C Smith, Elisabeth Lasater, Melissa Mccreery, Kimberly Lin, Whitney Stewart, Lauren E Damon, Alexander E Perl, Grace R Jeschke, Mayumi Sugita, Martin Carroll, Scott C. Kogan, Neil Shah. .
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    52. PML-RARa co-operates with Sox4 in acute myeloid leukemia development in mice. Haematologica. 2013 Mar; 98(3):424-7. Omidvar N, Maunakea ML, Jones L, Sevcikova S, Yin B, Himmel KL, Tennant TR, Le Beau MM, Largaespada DA, Kogan SC. PMID: 23144197.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    53. A dominantly acting murine allele of Mcm4 causes chromosomal abnormalities and promotes tumorigenesis. PLoS Genet. 2012; 8(11):e1003034. Bagley BN, Keane TM, Maklakova VI, Marshall JG, Lester RA, Cancel MM, Paulsen AR, Bendzick LE, Been RA, Kogan SC, Cormier RT, Kendziorski C, Adams DJ, Collier LS. PMID: 23133403.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    54. Genetically mediated Nf1 loss in mice promotes diverse radiation-induced tumors modeling second malignant neoplasms. Cancer Res. 2012 Dec 15; 72(24):6425-34. Choi G, Huang B, Pinarbasi E, Braunstein SE, Horvai AE, Kogan S, Bhatia S, Faddegon B, Nakamura JL. PMID: 23071067.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    55. An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model. Blood. 2012 May 10; 119(19):4512-23. Bergerson RJ, Collier LS, Sarver AL, Been RA, Lugthart S, Diers MD, Zuber J, Rappaport AR, Nixon MJ, Silverstein KA, Fan D, Lamblin AF, Wolff L, Kersey JH, Delwel R, Lowe SW, O'Sullivan MG, Kogan SC, Adams DJ, Largaespada DA. PMID: 22427200.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    56. Heterozygous Germ Line Deletion of a 2Mb Interval in Mice That Models Loss of 7q22 in Human Myeloid Malignancies Results in Defective Hematopoietic Stem Cell Function Reminiscent of Premature Aging. Blood. 2011 Nov 18; 118(21):2340-2340. Jasmine C. Wong, Kelley Weinfurtner, Yan Zhang, Pilar Alzamora, Eugene Hwang, Scott C. Kogan, Kevin M. Shannon. .
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    57. Control of the senescence-associated secretory phenotype by NF-?B promotes senescence and enhances chemosensitivity. Genes Dev. 2011 Oct 15; 25(20):2125-36. Chien Y, Scuoppo C, Wang X, Fang X, Balgley B, Bolden JE, Premsrirut P, Luo W, Chicas A, Lee CS, Kogan SC, Lowe SW. PMID: 21979375.
      View in: PubMed   Mentions: 287     Fields:    Translation:HumansAnimalsCells
    58. PML-RARa enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway. Autophagy. 2011 Oct; 7(10):1132-44. Huang Y, Hou JK, Chen TT, Zhao XY, Yan ZW, Zhang J, Yang J, Kogan SC, Chen GQ. PMID: 21673516.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    59. Donor myocardial infarction impairs the therapeutic potential of bone marrow cells by an interleukin-1-mediated inflammatory response. Sci Transl Med. 2011 Sep 14; 3(100):100ra90. Wang X, Takagawa J, Lam VC, Haddad DJ, Tobler DL, Mok PY, Zhang Y, Clifford BT, Pinnamaneni K, Saini SA, Su R, Bartel MJ, Sievers RE, Carbone L, Kogan S, Yeghiazarians Y, Hermiston M, Springer ML. PMID: 21918107.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    60. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature. 2011 Aug 03; 478(7370):524-8. Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA, Magoon D, Qi J, Blatt K, Wunderlich M, Taylor MJ, Johns C, Chicas A, Mulloy JC, Kogan SC, Brown P, Valent P, Bradner JE, Lowe SW, Vakoc CR. PMID: 21814200.
      View in: PubMed   Mentions: 852     Fields:    Translation:HumansAnimalsCells
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    66. Mutant BCL2 Co-Operates with CBFß/PEBP2ß-MYH11 to Promote Expansion of Leukemia Initiating Cells with a Predominantly Pro-Apoptotic Mechanism Via Recruitment of Ras-GTP In a Mouse Model of Progressive Acute Myeloid Leukemia. Blood. 2010 Nov 19; 116(21):1050-1050. Nader Omidvar, Carole Le Pogam, Stephanie Beurlet, Maria-Elena Noguera, Ann Janin, Scott C. Kogan, Irving L. Weissman, Marika Pla, Christine Chomienne, Rose Ann Padua. .
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    81. Fractionated Cranial Irradiation Induces a Distinctive Pattern of Second Malignant Neoplasms in Nf1 Mutant Mice. International Journal of Radiation Oncology • Biology • Physics. 2008 Sep 1; 72(1):s83. J.L. Nakamura, C. Phong, S. Kogan, S. Vandenberg, R.O. Pieper, K. Shannon. .
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    83. Survival and tumorigenesis in O6-methylguanine DNA methyltransferase-deficient mice following cyclophosphamide exposure. Mutagenesis. 2008 Sep; 23(5):341-6. Nagasubramanian R, Hansen RJ, Delaney SM, Cherian MM, Samson LD, Kogan SC, Dolan ME. PMID: 18477655.
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    85. Novel Mll-AF9 Cooperating Genes Identified in a Leukemogenesis Screen Using Retroviral Mutagenesis. Blood. 2007 Nov 16; 110(11):825-825. Rachel J. Bergerson, Lara S. Collier, Raha Allaei, Kevin A. Silverstein, Anne-Francoise F. Lamblin, Linda Wolff, Scott C. Kogan, John H. Kersey, David J. Adams, David A. Largaespada. .
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    95. New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors. Cell. 2006 Jul 28; 126(2):415-26. Forsberg EC, Serwold T, Kogan S, Weissman IL, Passegué E. PMID: 16873070.
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    96. CCAAT/enhancer binding proteins alpha and epsilon cooperate with all-trans retinoic acid in therapy but differ in their antileukemic activities. Blood. 2006 Oct 01; 108(7):2416-9. Lee YJ, Jones LC, Timchenko NA, Perrotti D, Tenen DG, Kogan SC. PMID: 16788101.
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    97. Trp53 loss during in vitro selection contributes to acquired Ara-C resistance in acute myeloid leukemia. Exp Hematol. 2006 May; 34(5):631-41. Yin B, Kogan SC, Dickins RA, Lowe SW, Largaespada DA. PMID: 16647569.
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    98. Loss of p53 impedes the antileukemic response to BCR-ABL inhibition. Proc Natl Acad Sci U S A. 2006 May 09; 103(19):7444-9. Wendel HG, de Stanchina E, Cepero E, Ray S, Emig M, Fridman JS, Veach DR, Bornmann WG, Clarkson B, McCombie WR, Kogan SC, Hochhaus A, Lowe SW. PMID: 16651519.
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    99. Increased CCAAT enhancer-binding protein epsilon (C/EBPepsilon) expression and premature apoptosis in myeloid cells expressing Gfi-1 N382S mutant associated with severe congenital neutropenia. J Biol Chem. 2006 Apr 21; 281(16):10745-51. Zhuang D, Qiu Y, Kogan SC, Dong F. PMID: 16500901.
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    100. Forced retinoic acid receptor alpha homodimers prime mice for APL-like leukemia. Cancer Cell. 2006 Feb; 9(2):81-94. Sternsdorf T, Phan VT, Maunakea ML, Ocampo CB, Sohal J, Silletto A, Galimi F, Le Beau MM, Evans RM, Kogan SC. PMID: 16473276.
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    101. Arsenite pre-conditioning reduces UVB-induced apoptosis in corneal epithelial cells through the anti-apoptotic activity of 27 kDa heat shock protein (HSP27). J Cell Physiol. 2006 Feb; 206(2):301-8. Shi B, Isseroff RR. PMID: 16126841.
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    103. Investigation of Hematopoietic Stem Cell and Progenitor Populations: Implication for Cell Fate Determination and Lineage Commitment. Blood. 2005 Nov 16; 106(11):801-801. Emmanuelle Passegue, Camilla Forsberg, Thomas Serwold, Scott Kogan, Irving L. Weissman. .
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    107. Induction of tumor arrest and differentiation with prolonged survival by intermittent hypoxia in a mouse model of acute myeloid leukemia. Blood. 2006 Jan 15; 107(2):698-707. Liu W, Guo M, Xu YB, Li D, Zhou ZN, Wu YL, Chen Z, Kogan SC, Chen GQ. PMID: 16166593.
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    108. Cooperation of Cytokine Signaling with Chimeric Transcription Factors in Leukemogenesis: PML-Retinoic Acid Receptor Alpha Blocks Growth Factor-Mediated Differentiation. Molecular and Cellular Biology. 2005 Jul 1; 25(13):5787-5787. Vernon T. Phan, David B. Shultz, Bao-Tran H. Truong, Timothy J. Blake, Anna L. Brown, Thomas J. Gonda, Michelle M. Le Beau, Scott C. Kogan. .
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    110. Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease. EMBO J. 2005 Jan 26; 24(2):368-81. Wang J, Iwasaki H, Krivtsov A, Febbo PG, Thorner AR, Ernst P, Anastasiadou E, Kutok JL, Kogan SC, Zinkel SS, Fisher JK, Hess JL, Golub TR, Armstrong SA, Akashi K, Korsmeyer SJ. PMID: 15635450.
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    111. O-14 A reversible two-step model ofMDS/preleukemia: Transgenic mice expressing inducible BCL2 and mutant NRAS. Leukemia Research. 2005 Jan 1; 29:s5. R.A. Padua, N. Omidvar, S. Kogan, T.-H. Phan, R. West, D. Felsher, I. Weissmann, S. Thomas, J. Whittaker, A. Janin, M. Pla, G. Muftis, J.M. Bishop, C. Chomienne. .
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    113. Identification of Cooperating Genetic Alterations in RUNX Leukemia Using the Mouse Model for the Human Familial Leukemia, FPD/AML. Blood. 2004 Nov 16; 104(11):3383-3383. Motomi Osato, Namiko Yamashita, Masatoshi Yanagida, Liqun Huang, Scott Kogan, Masayuki Iwasaki, Takuro Nakamura, Katsuya Shigesada, Norio Asou, Yoshiaki Ito. .
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    118. HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo. Blood. 2005 Feb 15; 105(4):1456-66. Fischbach NA, Rozenfeld S, Shen W, Fong S, Chrobak D, Ginzinger D, Kogan SC, Radhakrishnan A, Le Beau MM, Largman C, Lawrence HJ. PMID: 15522959.
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    119. Myeloid Malignancies. Mouse Models of Human Cancer. 2004 Oct 15. Scott C. Kogan. .
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    123. The role of p53 in suppression of KSHV cyclin-induced lymphomagenesis. Cancer Res. 2004 Jan 15; 64(2):581-9. Verschuren EW, Hodgson JG, Gray JW, Kogan S, Jones N, Evan GI. PMID: 14744772.
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    125. PML-RARA-targeted DNA vaccine induces protective immunity in a mouse model of leukemia. Nat Med. 2003 Nov; 9(11):1413-7. Padua RA, Larghero J, Robin M, le Pogam C, Schlageter MH, Muszlak S, Fric J, West R, Rousselot P, Phan TH, Mudde L, Teisserenc H, Carpentier AF, Kogan S, Degos L, Pla M, Bishop JM, Stevenson F, Charron D, Chomienne C. PMID: 14566333.
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