Scott Soifer, MD

Title(s)Professor, Pediatrics
SchoolSchool of Medicine
Address550 16th. Street
San Francisco CA 94158
Phone415-476-6083
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    University of California, San FranciscoResidency School of Medicine

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    ABNORMAL FETAL LUNG CIRCULATION--VASOACTIVE MEDIATORS
    NIH R01HL035518Jul 1, 1986 - May 31, 2000
    Role: Principal Investigator
    PULMONARY HYPERTENSION AND LUNG DISEASE IN THE NEWBORN
    NIH R23HL029941Jan 1, 1983 - Dec 31, 1985
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Harnessing Viscous Flow to Simplify the Actuation of Fluidic Soft Robots. Soft Robot. 2020 02; 7(1):1-9. Vasios N, Gross AJ, Soifer S, Overvelde JTB, Bertoldi K. PMID: 31070518.
      View in: PubMed   Mentions: 4     Fields:    
    2. Effect of enalaprilat on postoperative hypertension after surgical repair of coarctation of the aorta. Pediatr Crit Care Med. 2003 Jul; 4(3):327-32. Rouine-Rapp K, Mello DM, Hanley FL, Mohan Reddy V, Soifer S. PMID: 12831415.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    3. Expression of VEGF and its receptors Flt-1 and Flk-1/KDR is altered in lambs with increased pulmonary blood flow and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2003 Jul; 285(1):L222-31. Mata-Greenwood E, Meyrick B, Soifer SJ, Fineman JR, Black SM. PMID: 12665467.
      View in: PubMed   Mentions: 24  Translation:AnimalsCells
    4. Cyclic mechanical stretch induces VEGF and FGF-2 expression in pulmonary vascular smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2002 May; 282(5):L897-903. Quinn TP, Schlueter M, Soifer SJ, Gutierrez JA. PMID: 11943652.
      View in: PubMed   Mentions: 25  Translation:AnimalsCells
    5. A receptor for vascular endothelial growth factor that stimulates endothelial apoptosis. Cancer Res. 2001 Dec 15; 61(24):8629-37. Quinn TP, Soifer SJ, Ramer K, Williams LT, Nakamura MC. PMID: 11751375.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. Altered regulation of the ET-1 cascade in lambs with increased pulmonary blood flow and pulmonary hypertension. Pediatr Res. 2000 Jan; 47(1):97-106. Black SM, Bekker JM, Johengen MJ, Parry AJ, Soifer SJ, Fineman JR. PMID: 10625089.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    7. Altered endothelial function in lambs with pulmonary hypertension and acute lung injury. Pediatr Pulmonol. 1999 Mar; 27(3):147-56. Fineman JR, Wong J, Mikhailov T, Vanderford PA, Jerome HE, Soifer SJ. PMID: 10213252.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    8. Coordinated regulation of genes of the nitric oxide and endothelin pathways during the development of pulmonary hypertension in fetal lambs. Pediatr Res. 1998 Dec; 44(6):821-30. Black SM, Johengen MJ, Soifer SJ. PMID: 9853913.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    9. Increased endothelial NOS in lambs with increased pulmonary blood flow and pulmonary hypertension. Am J Physiol. 1998 11; 275(5):H1643-51. Black SM, Fineman JR, Steinhorn RH, Bristow J, Soifer SJ. PMID: 9815072.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    10. Increased pulmonary blood flow alters the molecular regulation of vascular reactivity in the lamb. Chest. 1998 Jul; 114(1 Suppl):39S. Black S, Fineman J, Johengen M, Bristow J, Soifer S. PMID: 9676621.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    11. Ventilation and oxygenation induce endothelial nitric oxide synthase gene expression in the lungs of fetal lambs. J Clin Invest. 1997 Sep 15; 100(6):1448-58. Black SM, Johengen MJ, Ma ZD, Bristow J, Soifer SJ. PMID: 9294110; PMCID: PMC508323.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    12. Nonsustained ventricular tachycardia in severe heart failure. Independent marker of increased mortality due to sudden death. GESICA-GEMA Investigators. Circulation. 1996 Dec 15; 94(12):3198-203. Doval HC, Nul DR, Grancelli HO, Varini SD, Soifer S, Corrado G, Dubner S, Scapin O, Perrone SV. PMID: 8989129.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCTClinical Trials
    13. Expression of neuronal nitric oxide synthase corresponds to regions of selective vulnerability to hypoxia-ischaemia in the developing rat brain. Neurobiol Dis. 1995 Jun; 2(3):145-55. Black SM, Bedolli MA, Martinez S, Bristow JD, Ferriero DM, Soifer SJ. PMID: 9173998.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    14. Endothelinb receptor agonists produce pulmonary vasodilation in intact newborn lambs with pulmonary hypertension. J Cardiovasc Pharmacol. 1995 Feb; 25(2):207-15. Wong J, Vanderford PA, Winters J, Soifer SJ, Fineman JR. PMID: 7752646.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    15. Regulation of pulmonary vascular tone in the perinatal period. Annu Rev Physiol. 1995; 57:115-34. Fineman JR, Soifer SJ, Heymann MA. PMID: 7778860.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    16. Developmental effects of endothelin-1 on the pulmonary circulation in sheep. Pediatr Res. 1994 Sep; 36(3):394-401. Wong J, Vanderford PA, Fineman JR, Soifer SJ. PMID: 7808838.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    17. Use of ATP-MgCl2 in the evaluation and treatment of children with pulmonary hypertension secondary to congenital heart defects. Circulation. 1994 Sep; 90(3):1287-93. Brook MM, Fineman JR, Bolinger AM, Wong AF, Heymann MA, Soifer SJ. PMID: 8087937.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    18. Chronic nitric oxide inhibition in utero produces persistent pulmonary hypertension in newborn lambs. J Clin Invest. 1994 Jun; 93(6):2675-83. Fineman JR, Wong J, Morin FC, Wild LM, Soifer SJ. PMID: 8201005; PMCID: PMC294514.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    19. HA1004, an intracellular calcium antagonist, selectively attenuates pulmonary hypertension in newborn lambs. J Cardiovasc Pharmacol. 1994 May; 23(5):806-13. Crowley MR, Fineman JR, Soifer SJ. PMID: 7521465.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    20. Diethylamine/nitric oxide (NO) adduct, an NO donor, produces potent pulmonary and systemic vasodilation in intact newborn lambs. J Cardiovasc Pharmacol. 1994 Jan; 23(1):113-9. Vanderford PA, Wong J, Chang R, Keefer LK, Soifer SJ, Fineman JR. PMID: 7511722.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    21. Disparate temporal expression of the prothrombin and thrombin receptor genes during mouse development. Am J Pathol. 1994 Jan; 144(1):60-9. Soifer SJ, Peters KG, O'Keefe J, Coughlin SR. PMID: 8291612; PMCID: PMC1887128.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    22. Endothelin-1 produces pulmonary vasodilation in the intact newborn lamb. Am J Physiol. 1993 Oct; 265(4 Pt 2):H1318-25. Wong J, Vanderford PA, Fineman JR, Chang R, Soifer SJ. PMID: 8238420.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    23. Pulmonary hypertension: physiologic or pathologic disease? Crit Care Med. 1993 Sep; 21(9 Suppl):S370-4. Soifer SJ. PMID: 8365235.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Hyperoxia and alkalosis produce pulmonary vasodilation independent of endothelium-derived nitric oxide in newborn lambs. Pediatr Res. 1993 Apr; 33(4 Pt 1):341-6. Fineman JR, Wong J, Soifer SJ. PMID: 8479813.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    25. M&B 22948, a cGMP phosphodiesterase inhibitor, is a pulmonary vasodilator in lambs. Am J Physiol. 1993 Jan; 264(1 Pt 2):H252-8. Braner DA, Fineman JR, Chang R, Soifer SJ. PMID: 8381611.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    26. Endothelin-1 does not mediate acute hypoxic pulmonary vasoconstriction in the intact newborn lamb. J Cardiovasc Pharmacol. 1993; 22 Suppl 8:S262-6. Wong J, Vanderford PA, Winters JW, Chang R, Soifer SJ, Fineman JR. PMID: 7509961.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    27. EDRF inhibition attenuates the increase in pulmonary blood flow due to oxygen ventilation in fetal lambs. J Appl Physiol (1985). 1992 Nov; 73(5):2151-7. Moore P, Velvis H, Fineman JR, Soifer SJ, Heymann MA. PMID: 1474097.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    28. Thrombin receptor expression in normal and atherosclerotic human arteries. J Clin Invest. 1992 Oct; 90(4):1614-21. Nelken NA, Soifer SJ, O'Keefe J, Vu TK, Charo IF, Coughlin SR. PMID: 1328304; PMCID: PMC443210.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    29. K+ channel pulmonary vasodilation in fetal lambs: role of endothelium-derived nitric oxide. J Appl Physiol (1985). 1992 Jul; 73(1):188-94. Chang JK, Moore P, Fineman JR, Soifer SJ, Heymann MA. PMID: 1506367.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    30. EDRF inhibition augments pulmonary hypertension in intact newborn lambs. Am J Physiol. 1992 May; 262(5 Pt 2):H1365-71. Fineman JR, Chang R, Soifer SJ. PMID: 1590440.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    31. L-Arginine, a precursor of EDRF in vitro, produces pulmonary vasodilation in lambs. Am J Physiol. 1991 Nov; 261(5 Pt 2):H1563-9. Fineman JR, Chang R, Soifer SJ. PMID: 1659228.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    32. Hemodynamic effects of oleic acid in newborn lambs: role of arachidonic acid metabolites. J Dev Physiol. 1991 Sep; 16(3):167-72. Schreiber MD, Soifer SJ. PMID: 1797924.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    33. In vivo attenuation of endothelium-dependent pulmonary vasodilation by methylene blue. J Appl Physiol (1985). 1991 Aug; 71(2):735-41. Fineman JR, Crowley MR, Heymann MA, Soifer SJ. PMID: 1657862.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    34. N omega-nitro-L-arginine attenuates endothelium-dependent pulmonary vasodilation in lambs. Am J Physiol. 1991 Apr; 260(4 Pt 2):H1299-306. Fineman JR, Heymann MA, Soifer SJ. PMID: 1849373.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    35. Effects of vasoactive drugs on thromboxane A2 mimetic-induced pulmonary hypertension in newborn lambs. Pediatr Res. 1991 Feb; 29(2):167-72. Crowley MR, Fineman JR, Soifer SJ. PMID: 2014153.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    36. The role of pulmonary vascular endothelium in perinatal pulmonary circulatory regulation. Semin Perinatol. 1991 Feb; 15(1):58-62. Fineman JR, Soifer SJ, Heymann MA. PMID: 2063230.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    37. Selective pulmonary vasodilation with ATP-MgCl2 during pulmonary hypertension in lambs. J Appl Physiol (1985). 1990 Nov; 69(5):1836-42. Fineman JR, Crowley MR, Soifer SJ. PMID: 2272976.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    38. Leukotrienes C4, D4, and E4 in fetal lamb tracheal fluid. J Dev Physiol. 1990 Jul; 14(1):37-41. Velvis H, Krusell J, Roman C, Soifer SJ, Riemer RK, Heymann MA. PMID: 1965438.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    39. Plasma epinephrine concentrations after intraosseous and central venous injection during cardiopulmonary resuscitation in the lamb. J Pediatr. 1990 Feb; 116(2):312-5. Andropoulos DB, Soifer SJ, Schreiber MD. PMID: 2299508.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    40. Bradykinin produces pulmonary vasodilation in fetal lambs: role of prostaglandin production. J Appl Physiol (1985). 1989 Oct; 67(4):1512-7. Frantz E, Soifer SJ, Clyman RI, Heymann MA. PMID: 2507510.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    41. Leukotriene antagonists attenuate thromboxane-inducible pulmonary hypertension. Pediatr Res. 1989 Aug; 26(2):83-7. Soifer SJ, Schreiber MD, Heymann MA. PMID: 2505220.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    42. Cromolyn sodium does not prevent hypoxia-induced pulmonary hypertension in newborn and young lambs. J Dev Physiol. 1988 Dec; 10(6):555-65. Frantz EG, Schreiber MD, Soifer SJ. PMID: 3149968.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    43. Respiratory alkalosis attenuates thromboxane-induced pulmonary hypertension. Crit Care Med. 1988 Dec; 16(12):1225-8. Schreiber MD, Soifer SJ. PMID: 3191739.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    44. Tricuspid regurgitation in children: a pulsed Doppler, contrast echocardiographic and angiographic comparison. J Am Soc Echocardiogr. 1988 Jul-Aug; 1(4):257-63. Martin GR, Silverman NH, Soifer SJ, Lutin WA, Scagnelli SA. PMID: 3272773.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    45. Effects of prostaglandin D2 on pulmonary arterial pressure and oxygenation in newborn infants with persistent pulmonary hypertension. J Pediatr. 1988 May; 112(5):774-7. Soifer SJ, Clyman RI, Heymann MA. PMID: 3162978.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    46. Leukotriene synthesis inhibition increases pulmonary blood flow in fetal lambs. Chest. 1988 Mar; 93(3 Suppl):117S. Heymann MA, LeBidois J, Soifer SJ, Clyman RI. PMID: 3125017.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    47. Piriprost: a putative leukotriene synthesis inhibitor increases pulmonary blood flow in fetal lambs. Pediatr Res. 1987 Sep; 22(3):350-4. Lebidois J, Soifer SJ, Clyman RI, Heymann MA. PMID: 3309861.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    48. Effects of activity on ascending aortic velocity in children with valvar aortic stenosis. Am J Cardiol. 1987 Jun 01; 59(15):1386-90. Martin GR, Soifer SJ, Silverman NH, Dae MW, Stanger P. PMID: 3591696.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    49. Umbilical cord compression produces pulmonary hypertension in newborn lambs: a model to study the pathophysiology of persistent pulmonary hypertension in the newborn. J Dev Physiol. 1987 Jun; 9(3):239-52. Soifer SJ, Kaslow D, Roman C, Heymann MA. PMID: 3112213.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    50. The differential effects of leukotriene C4 and D4 on the pulmonary and systemic circulations in newborn lambs. Pediatr Res. 1987 Feb; 21(2):176-82. Schreiber MD, Heymann MA, Soifer SJ. PMID: 3822598.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    51. Infant coarctation: a spectrum in clinical presentation and treatment. Ann Thorac Surg. 1986 Nov; 42(5):488-93. Yee ES, Soifer SJ, Turley K, Verrier ED, Fishman NH, Ebert PA. PMID: 3777999.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    52. Increased arterial pH, not decreased PaCO2, attenuates hypoxia-induced pulmonary vasoconstriction in newborn lambs. Pediatr Res. 1986 Feb; 20(2):113-7. Schreiber MD, Heymann MA, Soifer SJ. PMID: 3080725.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    53. Contrast echocardiography in the diagnosis of anomalous left coronary artery arising from the pulmonary artery. Pediatr Cardiol. 1986; 6(4):203-5. Martin GR, Cooper MJ, Silverman NH, Soifer SJ. PMID: 3703691.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    54. Thromboxane is not responsible for the high pulmonary vascular resistance in fetal lambs. Pediatr Res. 1985 Dec; 19(12):1254-7. Clozel M, Clyman RI, Soifer SJ, Heymann MA. PMID: 4080442.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    55. Leukotriene end organ antagonists increase pulmonary blood flow in fetal lambs. Am J Physiol. 1985 Sep; 249(3 Pt 2):H570-6. Soifer SJ, Loitz RD, Roman C, Heymann MA. PMID: 4037105.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    56. Leukotriene inhibition prevents and reverses hypoxic pulmonary vasoconstriction in newborn lambs. Pediatr Res. 1985 May; 19(5):437-41. Schreiber MD, Heymann MA, Soifer SJ. PMID: 4000769.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    57. Future research directions in persistent pulmonary hypertension of the newborn. Clin Perinatol. 1984 Oct; 11(3):745-55. Soifer SJ, Heymann MA. PMID: 6386274.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    58. Synthetic patch aortoplasty. A simplified approach for coarctation in repairs during early infancy and thereafter. Am J Surg. 1984 Aug; 148(2):240-3. Yee ES, Turley K, Soifer S, Ebert PA. PMID: 6380324.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    59. The developmental effects of prostaglandin D2 on the pulmonary and systemic circulations in the newborn lamb. J Dev Physiol. 1983 Aug; 5(4):237-50. Soifer SJ, Morin FC, Kaslow DC, Heymann MA. PMID: 6579103.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    60. Prostaglandin D2 reverses induced pulmonary hypertension in the newborn lamb. J Pediatr. 1982 Mar; 100(3):458-63. Soifer SJ, Morin FC, Heymann MA. PMID: 7199569.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    61. Detection of intracranial arteriovenous fistula by two-dimensional ultrasonography. Circulation. 1981 May; 63(5):1179-85. Snider AR, Soifer SJ, Silverman NH. PMID: 6451332.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
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