 Shaun Fontaine, PhD
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| Title(s) | ProLynx, Inc.-Scientist, Pharmaceutical Chemistry |
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| School | School of Pharmacy |
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| Address | 1700 4th Street
San Francisco CA 94158
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| Phone | 415-514-1367 |
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| vCard | Download vCard |
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 Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication.
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Attenuation of the Reaction of Michael Acceptors with Biologically Important Nucleophiles. Bioconjug Chem. 2021 Apr 06.
PMID: 33822591.
View in: PubMed Mentions: Fields:
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A very long-acting Poly(ADP-ribose) polymerase inhibitor suppresses cancer cell growth in DNA repair-deficient tumor models. Cancer Res. 2020 Dec 15.
Fontaine SD, Ashley GW, Houghton PJ, Kurmasheva RT, Diolaiti M, Ashworth A, Peer CJ, Nguyen R, Figg WD, Beckford-Vera DR, Santi DV. PMID: 33323380.
View in: PubMed Mentions: Fields:
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Prospective use of the single-mouse experimental design for the evaluation of PLX038A. Cancer Chemother Pharmacol. 2020 02; 85(2):251-263.
Ghilu S, Li Q, Fontaine SD, Santi DV, Kurmasheva RT, Zheng S, Houghton PJ. PMID: 31927611.
View in: PubMed Mentions: 1 Fields: Translation: AnimalsCells
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PET Imaging of the EPR Effect in Tumor Xenografts Using Small 15 nm Diameter Polyethylene Glycols Labeled with Zirconium-89. . 2020 02; 19(2):673-679.
Beckford Vera DR, Fontaine SD, VanBrocklin HF, Hearn BR, Reid R, Ashley GW, Santi DV. PMID: 31744896.
View in: PubMed Mentions:
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PLX038: a PEGylated prodrug of SN-38 independent of UGT1A1 activity. Cancer Chemother Pharmacol. 2020 01; 85(1):225-229.
Fontaine SD, Santi AD, Reid R, Smith PC, Ashley GW, Santi DV. PMID: 31707444.
View in: PubMed Mentions: Fields: Translation: Animals
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Species-specific optimization of PEG~SN-38 prodrug pharmacokinetics and antitumor effects in a triple-negative BRCA1-deficient xenograft. Cancer Chemother Pharmacol. 2019 10; 84(4):729-738.
Fontaine SD, Hann B, Reid R, Ashley GW, Santi DV. PMID: 31321449.
View in: PubMed Mentions: 1 Fields: Translation: AnimalsCells
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Primary deuterium kinetic isotope effects prolong drug release and polymer biodegradation in a drug delivery system. J Control Release. 2018 05 28; 278:74-79.
Hearn BR, Fontaine SD, Pfaff SJ, Schneider EL, Henise J, Ashley GW, Santi DV. PMID: 29577950.
View in: PubMed Mentions: Fields: Translation: AnimalsCells
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A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models. J Med Chem. 2016 12 22; 59(24):11161-11170.
Spangler B, Fontaine SD, Shi Y, Sambucetti L, Mattis AN, Hann B, Wells JA, Renslo AR. PMID: 27936709.
View in: PubMed Mentions: 6 Fields: Translation: HumansAnimalsCells
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Approach for Half-Life Extension of Small Antibody Fragments That Does Not Affect Tissue Uptake. Bioconjug Chem. 2016 Oct 19; 27(10):2534-2539.
Schneider EL, Hearn BR, Pfaff SJ, Fontaine SD, Reid R, Ashley GW, Grabulovski S, Strassberger V, Vogt L, Jung T, Santi DV. PMID: 27657443.
View in: PubMed Mentions: 2 Fields:
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A reactivity-based probe of the intracellular labile ferrous iron pool. Nat Chem Biol. 2016 09; 12(9):680-5.
Spangler B, Morgan CW, Fontaine SD, Vander Wal MN, Chang CJ, Wells JA, Renslo AR. PMID: 27376690.
View in: PubMed Mentions: 20 Fields: Translation: HumansCells
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Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response. ChemMedChem. 2016 Apr 19; 11(8):870-80.
Hearn BR, Jaishankar P, Sidrauski C, Tsai JC, Vedantham P, Fontaine SD, Walter P, Renslo AR. PMID: 26789650.
View in: PubMed Mentions: 4 Fields: Translation: HumansCells
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Trioxolane-Mediated Delivery of Mefloquine Limits Brain Exposure in a Mouse Model of Malaria. ACS Med Chem Lett. 2015 Nov 12; 6(11):1145-9.
Lauterwasser EM, Fontaine SD, Li H, Gut J, Katneni K, Charman SA, Rosenthal PJ, Bogyo M, Renslo AR. PMID: 26617969.
View in: PubMed Mentions:
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High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations. Sci Rep. 2015 Sep 25; 5:13891.
Mott BT, Eastman RT, Guha R, Sherlach KS, Siriwardana A, Shinn P, McKnight C, Michael S, Lacerda-Queiroz N, Patel PR, Khine P, Sun H, Kasbekar M, Aghdam N, Fontaine SD, Liu D, Mierzwa T, Mathews-Griner LA, Ferrer M, Renslo AR, Inglese J, Yuan J, Roepe PD, Su XZ, Thomas CJ. PMID: 26403635.
View in: PubMed Mentions: 29 Fields: Translation: HumansAnimalsCells
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Long-term stabilization of maleimide-thiol conjugates. Bioconjug Chem. 2015 Jan 21; 26(1):145-52.
Fontaine SD, Reid R, Robinson L, Ashley GW, Santi DV. PMID: 25494821.
View in: PubMed Mentions: 35 Fields:
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Efficient and stereocontrolled synthesis of 1,2,4-trioxolanes useful for ferrous iron-dependent drug delivery. Org Lett. 2014 Nov 07; 16(21):5776-9.
Fontaine SD, DiPasquale AG, Renslo AR. PMID: 25331549.
View in: PubMed Mentions: 11 Fields: Translation: HumansAnimalsCells
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Drug delivery to the malaria parasite using an arterolane-like scaffold. ChemMedChem. 2015 Jan; 10(1):47-51.
Fontaine SD, Spangler B, Gut J, Lauterwasser EM, Rosenthal PJ, Renslo AR. PMID: 25314098.
View in: PubMed Mentions: 10 Fields: Translation: AnimalsCells
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Synthetic studies on the mycolactone core. Org Biomol Chem. 2010 Nov 21; 8(22):5159-65.
Ko KS, Alexander MD, Fontaine SD, Biggs-Houck JE, La Clair JJ, Burkart MD. PMID: 20844795.
View in: PubMed Mentions: 4 Fields: Translation: Cells
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Synthesis of the mycolactone core by ring-closing metathesis. Chem Commun (Camb). 2006 Nov 28; (44):4602-4.
Alexander MD, Fontaine SD, La Clair JJ, Dipasquale AG, Rheingold AL, Burkart MD. PMID: 17082856.
View in: PubMed Mentions: 7 Fields: Translation: Cells
This graph shows the total number of publications by year. To see the data as text, click here.
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| Year | Publications |
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| 2006 | 1 | | 2010 | 1 | | 2014 | 3 | | 2015 | 2 | | 2016 | 4 | | 2018 | 1 | | 2019 | 3 | | 2020 | 2 | | 2021 | 1 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
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