Shivani Malik, PhD

TitlePostdoctoral Scholar
SchoolUCSF School of Medicine
Address1450 Third St
San Francisco CA 94158
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Roy N, Takeuchi KK, Ruggeri JM, Bailey P, Chang D, Li J, Leonhardt L, Puri S, Hoffman MT, Gao S, Halbrook CJ, Song Y, Ljungman M, Malik S, Wright CV, Dawson DW, Biankin AV, Hebrok M, Crawford HC. PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance. Genes Dev. 2016 Dec 15; 30(24):2669-2683. PMID: 28087712.
      View in: PubMed
    2. Malik S, Villanova L, Tanaka S, Aonuma M, Roy N, Berber E, Pollack JR, Michishita-Kioi E, Chua KF. SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors. Sci Rep. 2015 Apr 29; 5:9841. PMID: 25923013; PMCID: PMC4413894.
    3. Roy N, Malik S, Villanueva KE, Urano A, Lu X, Von Figura G, Seeley ES, Dawson DW, Collisson EA, Hebrok M. Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation. Genes Dev. 2015 Mar 15; 29(6):658-71. PMID: 25792600; PMCID: PMC4378197.
    4. Malik S, Bhaumik SR. Regulation of active genome integrity and expression by Rad26p. Nucleus. 2014; 5(6):520-6. PMID: 25484185; PMCID: PMC4615787.
    5. Sen R, Malik S, Frankland-Searby S, Uprety B, Lahudkar S, Bhaumik SR. Rrd1p, an RNA polymerase II-specific prolyl isomerase and activator of phosphoprotein phosphatase, promotes transcription independently of rapamycin response. Nucleic Acids Res. 2014 Sep; 42(15):9892-907. PMID: 25114048; PMCID: PMC4150799.
    6. Malik S, Durairaj G, Bhaumik SR. Mechanisms of antisense transcription initiation from the 3' end of the GAL10 coding sequence in vivo. Mol Cell Biol. 2013 Sep; 33(18):3549-67. PMID: 23836882; PMCID: PMC3753873.
    7. Malik S, Bhaumik SR. Rad26p, a transcription-coupled repair factor, promotes the eviction and prevents the reassociation of histone H2A-H2B dimer during transcriptional elongation in vivo. Biochemistry. 2012 Jul 31; 51(30):5873-5. PMID: 22794311; PMCID: PMC3447996.
    8. Malik S, Chaurasia P, Lahudkar S, Uprety B, Bhaumik SR. Rad26p regulates the occupancy of histone H2A-H2B dimer at the active genes in vivo. Nucleic Acids Res. 2012 Apr; 40(8):3348-63. PMID: 22199252; PMCID: PMC3333851.
    9. Uprety B, Lahudkar S, Malik S, Bhaumik SR. The 19S proteasome subcomplex promotes the targeting of NuA4 HAT to the promoters of ribosomal protein genes to facilitate the recruitment of TFIID for transcriptional initiation in vivo. Nucleic Acids Res. 2012 Mar; 40(5):1969-83. PMID: 22086954; PMCID: PMC3300024.
    10. Durairaj G, Chaurasia P, Lahudkar S, Malik S, Shukla A, Bhaumik SR. Regulation of chromatin assembly/disassembly by Rtt109p, a histone H3 Lys56-specific acetyltransferase, in vivo. J Biol Chem. 2010 Oct 01; 285(40):30472-9. PMID: 20668333; PMCID: PMC2945540.
    11. Malik S, Bhaumik SR. Mixed lineage leukemia: histone H3 lysine 4 methyltransferases from yeast to human. FEBS J. 2010 Apr; 277(8):1805-21. PMID: 20236312; PMCID: PMC2873088.
    12. Malik S, Shukla A, Sen P, Bhaumik SR. The 19 s proteasome subcomplex establishes a specific protein interaction network at the promoter for stimulated transcriptional initiation in vivo. J Biol Chem. 2009 Dec 18; 284(51):35714-24. PMID: 19843524; PMCID: PMC2791002.
    13. Malik S, Chaurasia P, Lahudkar S, Durairaj G, Shukla A, Bhaumik SR. Rad26p, a transcription-coupled repair factor, is recruited to the site of DNA lesion in an elongating RNA polymerase II-dependent manner in vivo. Nucleic Acids Res. 2010 Mar; 38(5):1461-77. PMID: 20007604; PMCID: PMC2836574.
    14. Bhaumik SR, Malik S. Diverse regulatory mechanisms of eukaryotic transcriptional activation by the proteasome complex. Crit Rev Biochem Mol Biol. 2008 Nov-Dec; 43(6):419-33. PMID: 19058045.
      View in: PubMed
    15. Malik S, Bagla S, Chaurasia P, Duan Z, Bhaumik SR. Elongating RNA polymerase II is disassembled through specific degradation of its largest but not other subunits in response to DNA damage in vivo. J Biol Chem. 2008 Mar 14; 283(11):6897-905. PMID: 18195014.
      View in: PubMed
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