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Simon Bucher, PhD

Title(s)Postdoctoral Scholar, Medicine
SchoolSchool of Medicine
Address513 Parnassus Ave, HSE
San Francisco CA 94143
Phone415-476-6160
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity. Cell Biol Toxicol. 2020 Jun 14. Allard J, Bucher S, Massart J, Ferron PJ, Le Guillou D, Loyant R, Daniel Y, Launay Y, Buron N, Begriche K, Borgne-Sanchez A, Fromenty B. PMID: 32535746.
      View in: PubMed   Mentions:    Fields:    
    2. Non-oxidative ethanol metabolism in human hepatic cells in vitro: Involvement of uridine diphospho-glucuronosyltransferase 1A9 in ethylglucuronide production. Toxicol In Vitro. 2020 Aug; 66:104842. Hugbart C, Verres Y, Le Daré B, Bucher S, Vène E, Bodin A, Lagente V, Fromenty B, Bouvet R, Morel I, Loyer P, Gicquel T. PMID: 32283135.
      View in: PubMed   Mentions:    Fields:    
    3. Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending on their affinity for the aryl hydrocarbon receptor. Toxicol Sci. 2019 Jul 31. van Meteren N, Lagadic-Gossmann D, Chevanne M, Gallais I, Gobart D, Burel A, Bucher S, Grova N, Fromenty B, Appenzeller BMR, Chevance S, Gauffre F, Le Ferrec E, Sergent O. PMID: 31368503.
      View in: PubMed   Mentions: 1     Fields:    
    4. Moderate chronic ethanol consumption exerts beneficial effects on nonalcoholic fatty liver in mice fed a high-fat diet: possible role of higher formation of triglycerides enriched in monounsaturated fatty acids. Eur J Nutr. 2020 Jun; 59(4):1619-1632. Bucher S, Begriche K, Catheline D, Trak-Smayra V, Tiaho F, Coulouarn C, Pinon G, Lagadic-Gossmann D, Rioux V, Fromenty B. PMID: 31161349.
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    5. Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol: a possible key role for xenobiotic metabolism and nitric oxide. Free Radic Biol Med. 2018 12; 129:323-337. Tête A, Gallais I, Imran M, Chevanne M, Liamin M, Sparfel L, Bucher S, Burel A, Podechard N, Appenzeller BMR, Fromenty B, Grova N, Sergent O, Lagadic-Gossmann D. PMID: 30268890.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    6. Production of chlorzoxazone glucuronides via cytochrome P4502E1 dependent and independent pathways in human hepatocytes. Arch Toxicol. 2018 10; 92(10):3077-3091. Quesnot N, Bucher S, Gade C, Vlach M, Vene E, Valença S, Gicquel T, Holst H, Robin MA, Loyer P. PMID: 30151596.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure. Oxid Med Cell Longev. 2018; 2018:4396403. Bucher S, Le Guillou D, Allard J, Pinon G, Begriche K, Tête A, Sergent O, Lagadic-Gossmann D, Fromenty B. PMID: 30147834.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    8. Drug-Induced Alterations of Mitochondrial DNA Homeostasis in Steatotic and Nonsteatotic HepaRG Cells. J Pharmacol Exp Ther. 2018 06; 365(3):711-726. Le Guillou D, Bucher S, Begriche K, Hoët D, Lombès A, Labbe G, Fromenty B. PMID: 29669730.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo. Sci Rep. 2018 04 13; 8(1):5963. Bucher S, Tête A, Podechard N, Liamin M, Le Guillou D, Chevanne M, Coulouarn C, Imran M, Gallais I, Fernier M, Hamdaoui Q, Robin MA, Sergent O, Fromenty B, Lagadic-Gossmann D. PMID: 29654281.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    10. Bisphenol a induces steatosis in HepaRG cells using a model of perinatal exposure. Environ Toxicol. 2017 Mar; 32(3):1024-1036. Bucher S, Jalili P, Le Guillou D, Begriche K, Rondel K, Martinais S, Zalko D, Corlu A, Robin MA, Fromenty B. PMID: 27322340.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsPHPublic Health
    11. A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophen. Toxicol Appl Pharmacol. 2016 Feb 01; 292:40-55. Michaut A, Le Guillou D, Moreau C, Bucher S, McGill MR, Martinais S, Gicquel T, Morel I, Robin MA, Jaeschke H, Fromenty B. PMID: 26739624.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    12. Protein kinase C-dependent regulation of human hepatic drug transporter expression. Biochem Pharmacol. 2015 Dec 15; 98(4):703-17. Mayati A, Le Vee M, Moreau A, Jouan E, Bucher S, Stieger B, Denizot C, Parmentier Y, Fardel O. PMID: 26462574.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    13. Modulation of metabolizing enzymes by bisphenol a in human and animal models. Chem Res Toxicol. 2014 Sep 15; 27(9):1463-73. Quesnot N, Bucher S, Fromenty B, Robin MA. PMID: 25142872.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    14. Regulation of hepatic drug transporter activity and expression by organochlorine pesticides. J Biochem Mol Toxicol. 2014 Mar; 28(3):119-28. Bucher S, Le Vee M, Jouan E, Fardel O. PMID: 24464585.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
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