Sindhu Chandran, MD

TitleAssociate Professor
InstitutionUniversity of California San Francisco
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    Collapse Biography 
    Collapse Education and Training
    All India Institute of Medical Sciences, New Delhi, IndiaM.B., B.S.2002School of Medicine
    University of Arizona, Tucson, AZInternship & Residency2007Medicine
    Stanford University, Palo Alto, CAClinical & Research Fellowship2010Nephrology
    University of California, San Francisco, San Francisco, CAClinical Fellowship 2011Transplant Nephrology

    Collapse Overview 
    Collapse Overview
    A transplant nephrologist with expertise in kidney and pancreas transplantation, Dr. Chandran earned her medical degree at All India Institute of Medical Sciences, and completed her residency at the University of Arizona. After completing her nephrology fellowship at Stanford University, she joined UCSF in 2010 for additional training in kidney transplantation and stayed on as a member of the transplant nephrology faculty. She is currently the Director of the Inpatient Kidney Transplant Unit.

    Dr. Chandran is a member of the American Society of Nephrology and the American Society of Transplantation. She is board certified in internal medicine and nephrology. She has a strong background in renal physiology dating back to her research fellowship at Stanford during which she worked on the mechanisms of sodium transport in the distal nephron. At UCSF, she has focused her research interests on the treatment of renal graft inflammation with novel immunosuppressive regimens including cellular therapy with the overall goal of improving long term graft survival. Dr. Chandran is also involved in studying therapies that can promote tolerance in her role as an Associate Director with the clinical trials group at the Immune Tolerance Network.

    Collapse Research 
    Collapse Research Activities and Funding
    Novel Therapies to Modulate the Inflammatory Alloresponse in Renal Grafts
    NIH U01AI113362Jul 1, 2014 - Jun 30, 2021
    Role: Co-Investigator
    Role Description: Protocol chair

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Wojciechowski D, Chandran S, Webber A, Hirose R, Vincenti F. Mycophenolate Mofetil Withdrawal With Conversion to Everolimus to Treat BK Virus Infection in Kidney Transplant Recipients. Transplant Proc. 2017 Oct; 49(8):1773-1778. PMID: 28923623.
      View in: PubMed
    2. Chandran S, Tang Q, Sarwal M, Laszik ZG, Putnam AL, Lee K, Leung J, Nguyen V, Sigdel T, Tavares EC, Yang JYC, Hellerstein M, Fitch M, Bluestone JA, Vincenti F. Polyclonal Regulatory T Cell Therapy for Control of Inflammation in Kidney Transplants. Am J Transplant. 2017 Nov; 17(11):2945-2954. PMID: 28675676.
      View in: PubMed
    3. Wojciechowski D, Chandran S, Yang JYC, Sarwal MM, Vincenti F. Retrospective evaluation of the efficacy and safety of belatacept with thymoglobulin induction and maintenance everolimus: A single-center clinical experience. Clin Transplant. 2017 Sep; 31(9). PMID: 28662293.
      View in: PubMed
    4. Lee BJ, McCulloch CE, Grimes BA, Chandran S, Allen IE, Delgado C, Hsu CY. Refining the Policy for Timing of Kidney Transplant Waitlist Qualification. Transplant Direct. 2017 Aug; 3(8):e195. PMID: 28795146.
      View in: PubMed
    5. Abend JR, Changala M, Sathe A, Casey F, Kistler A, Chandran S, Howard A, Wojciechowski D. Correlation of BK Virus Neutralizing Serostatus With the Incidence of BK Viremia in Kidney Transplant Recipients. Transplantation. 2017 06; 101(6):1495-1505. PMID: 27854236.
      View in: PubMed
    6. Wojciechowski D, Chandran S, Vincenti F. Early post-transplant conversion from tacrolimus to belatacept for prolonged delayed graft function improves renal function in kidney transplant recipients. Clin Transplant. 2017 May; 31(5). PMID: 28190259.
      View in: PubMed
    7. Chandran S, Stock PG. Opportunities and Challenges for Kidney Donation from and to HIV-Positive Individuals. Clin J Am Soc Nephrol. 2017 03 07; 12(3):385-387. PMID: 28232405.
      View in: PubMed
    8. Chandran S, Feng S. Current status of tolerance in kidney transplantation. Curr Opin Nephrol Hypertens. 2016 11; 25(6):591-601. PMID: 27636772.
      View in: PubMed
    9. Wojciechowski D, Chandran S. BK Virus Infection After Kidney Transplantation: The Data Are Mounting for a Personalized Approach. Transplantation. 2016 Apr; 100(4):703-4. PMID: 26760573.
      View in: PubMed
    10. Morgan TA, Chandran S, Burger IM, Zhang CA, Goldstein RB. Complications of Ultrasound-Guided Renal Transplant Biopsies. Am J Transplant. 2016 Apr; 16(4):1298-305. PMID: 26601796.
      View in: PubMed
    11. Safa K, Chandran S, Wojciechowski D. Erratum to: Pharmacologic Targeting of Regulatory T Cells for Solid Organ Transplantation: Current and Future Prospects. Drugs. 2015 Dec; 75(18):2171. PMID: 26553341.
      View in: PubMed
    12. Safa K, Chandran S, Wojciechowski D. Pharmacologic targeting of regulatory T cells for solid organ transplantation: current and future prospects. Drugs. 2015 Nov; 75(16):1843-52. PMID: 26493288.
      View in: PubMed
    13. Wu EH, Wojciechowski D, Chandran S, Yeh BM, Park M, Westphalen A, Wang ZJ. Prevalence of abdominal aortic calcifications in older living renal donors and its effect on graft function and histology. Transpl Int. 2015 Oct; 28(10):1172-8. PMID: 26011061.
      View in: PubMed
    14. Arroyo D, Chandran S, Vagefi PA, Wojciechowski D. Adjuvant Ciprofloxacin for Persistent BK Polyomavirus Infection in Kidney Transplant Recipients. J Transplant. 2014; 2014:107459. PMID: 25349720; PMCID: PMC4034659.
    15. Chandran S, Masharani U, Webber AB, Wojciechowski DM. Prediabetic living kidney donors have preserved kidney function at 10 years after donation. Transplantation. 2014 Apr 15; 97(7):748-54. PMID: 24342975.
      View in: PubMed
    16. Chandran S, Vincenti F. Clinical aspects: focusing on key unique organ-specific issues of renal transplantation. Cold Spring Harb Perspect Med. 2014 Feb 01; 4(2). PMID: 24370927; PMCID: PMC3904099.
    17. Wojciechowski D, Chandran S. Effect of ciprofloxacin combined with sulfamethoxazole-trimethoprim prophylaxis on the incidence of urinary tract infections after kidney transplantation. Transplantation. 2013 Aug 27; 96(4):400-5. PMID: 23698597.
      View in: PubMed
    18. Chandran S, Jen KY, Laszik ZG. Recurrent HIV-associated immune complex glomerulonephritis with lupus-like features after kidney transplantation. Am J Kidney Dis. 2013 Aug; 62(2):335-8. PMID: 23481367; PMCID: PMC4121438.
    19. Wojciechowski D, Chanda R, Chandran S, Lee B, Webber A, Macaraig M, Tomlanovich S, Vincenti F. Ciprofloxacin prophylaxis in kidney transplant recipients reduces BK virus infection at 3 months but not at 1 year. Transplantation. 2012 Dec 15; 94(11):1117-23. PMID: 23060281.
      View in: PubMed
    20. Freed MM, Ramirez-Valle F, Chandran S. Fever, hepatosplenomegaly and a skin nodule in a kidney-pancreas transplant recipient. Am J Transplant. 2012 Sep; 12(9):2556-8; quiz 2558. PMID: 22925186; PMCID: PMC4087158.
    21. Lockridge JB, Chandran S. The Scribner shunt: 50 years later. Kidney Int. 2012 Jan; 81(1):120. PMID: 22170532; PMCID: PMC4124935.
    22. Chandran S, Li H, Dong W, Krasinska K, Adams C, Alexandrova L, Chien A, Hallows KR, Bhalla V. Neural precursor cell-expressed developmentally down-regulated protein 4-2 (Nedd4-2) regulation by 14-3-3 protein binding at canonical serum and glucocorticoid kinase 1 (SGK1) phosphorylation sites. J Biol Chem. 2011 Oct 28; 286(43):37830-40. PMID: 21900244; PMCID: PMC3199524.
    23. Chandran S, Baxter-Lowe L, Olson JL, Tomlanovich SJ, Webber A. Eculizumab for the treatment of de novo thrombotic microangiopathy post simultaneous pancreas-kidney transplantation--a case report. Transplant Proc. 2011 Jun; 43(5):2097-101. PMID: 21693335.
      View in: PubMed
    24. Hallows KR, Bhalla V, Oyster NM, Wijngaarden MA, Lee JK, Li H, Chandran S, Xia X, Huang Z, Chalkley RJ, Burlingame AL, Pearce D. Phosphopeptide screen uncovers novel phosphorylation sites of Nedd4-2 that potentiate its inhibition of the epithelial Na+ channel. J Biol Chem. 2010 Jul 09; 285(28):21671-8. PMID: 20466724; PMCID: PMC2898378.
    25. Chandran S, Petersen J, Jacobs C, Fiorentino D, Doeden K, Lafayette RA. Imatinib in the treatment of nephrogenic systemic fibrosis. Am J Kidney Dis. 2009 Jan; 53(1):129-32. PMID: 19012999.
      View in: PubMed
    26. Bose S, Chandran S, Mirocha JM, Bose N. The Akt pathway in human breast cancer: a tissue-array-based analysis. Mod Pathol. 2006 Feb; 19(2):238-45. PMID: 16341149.
      View in: PubMed