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Precision targeting of the plasminogen activator inhibitor-1 mechanism increases efficacy of fibrinolytic therapy in empyema. Physiol Rep. 2021 05; 9(9):e14861.
Florova G, Girard RA, Azghani AO, Sarva K, Buchanan A, Karandashova S, DeVera CJ, Morris D, Chamiso M, Koenig K, Cines DB, Idell S, Komissarov AA. PMID: 33991465.
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Neutrophil elastase correlates with increased sphingolipid content in cystic fibrosis sputum. Pediatr Pulmonol. 2018 07; 53(7):872-880.
Karandashova S, Kummarapurugu A, Zheng S, Kang L, Sun S, Rubin BK, Voynow JA. PMID: 29624923.
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PubMed Mentions:
2 Fields:
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HumansAnimalsCells
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High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells. Am J Respir Cell Mol Biol. 2018 01; 58(1):126-128.
Kummarapurugu AB, Zheng S, Ledford J, Karandashova S, Voynow JA. PMID: 29286856.
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PubMed Mentions:
3 Fields:
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HumansCells
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Neutrophil elastase increases airway ceramide levels via upregulation of serine palmitoyltransferase. Am J Physiol Lung Cell Mol Physiol. 2018 01 01; 314(1):L206-L214.
Karandashova S, Kummarapurugu AB, Zheng S, Chalfant CE, Voynow JA. PMID: 29025713.
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3 Fields:
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Animals
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Targeting plasminogen activator inhibitor-1 in tetracycline-induced pleural injury in rabbits. . 2018 01 01; 314(1):L54-L68.
Florova G, Azghani AO, Karandashova S, Schaefer C, Yarovoi SV, Declerck PJ, Cines DB, Idell S, Komissarov AA. PMID: 28860148.
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Dose dependency of outcomes of intrapleural fibrinolytic therapy in new rabbit empyema models. . 2016 08 01; 311(2):L389-99.
Komissarov AA, Florova G, Azghani AO, Buchanan A, Boren J, Allen T, Rahman NM, Koenig K, Chamiso M, Karandashova S, Henry J, Idell S. PMID: 27343192.
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Targeting of plasminogen activator inhibitor 1 improves fibrinolytic therapy for tetracycline-induced pleural injury in rabbits. Am J Respir Cell Mol Biol. 2015 Apr; 52(4):429-37.
Florova G, Azghani A, Karandashova S, Schaefer C, Koenig K, Stewart-Evans K, Declerck PJ, Idell S, Komissarov AA. PMID: 25140386.
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11 Fields:
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Animals
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Plasminogen activator inhibitor-1 suppresses profibrotic responses in fibroblasts from fibrotic lungs. J Biol Chem. 2015 Apr 10; 290(15):9428-41.
Marudamuthu AS, Shetty SK, Bhandary YP, Karandashova S, Thompson M, Sathish V, Florova G, Hogan TB, Pabelick CM, Prakash YS, Tsukasaki Y, Fu J, Ikebe M, Idell S, Shetty S. PMID: 25648892.
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25 Fields:
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AnimalsCells
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Anaplasma phagocytophilum surface protein AipA mediates invasion of mammalian host cells. Cell Microbiol. 2014 Aug; 16(8):1133-45.
Seidman D, Ojogun N, Walker NJ, Mastronunzio J, Kahlon A, Hebert KS, Karandashova S, Miller DP, Tegels BK, Marconi RT, Fikrig E, Borjesson DL, Carlyon JA. PMID: 24612118.
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12 Fields:
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HumansAnimalsCells
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Active a-macroglobulin is a reservoir for urokinase after fibrinolytic therapy in rabbits with tetracycline-induced pleural injury and in human pleural fluids. . 2013 Nov 15; 305(10):L682-92.
Komissarov AA, Florova G, Azghani A, Karandashova S, Kurdowska AK, Idell S. PMID: 23997178.
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Remarkable stabilization of plasminogen activator inhibitor 1 in a "molecular sandwich" complex. Biochemistry. 2013 Jul 09; 52(27):4697-709.
Florova G, Karandashova S, Declerck PJ, Idell S, Komissarov AA. PMID: 23734661.
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10 Fields:
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Cells
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Intrapleural adenoviral delivery of human plasminogen activator inhibitor-1 exacerbates tetracycline-induced pleural injury in rabbits. Am J Respir Cell Mol Biol. 2013 Jan; 48(1):44-52.
Karandashova S, Florova G, Azghani AO, Komissarov AA, Koenig K, Tucker TA, Allen TC, Stewart K, Tvinnereim A, Idell S. PMID: 23002099.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells