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Stephen Kahl, PhD

Title(s)Professor, Pharmaceutical Chemistry
SchoolSchool of Pharmacy
Address513 Parnassus Ave, MSB
San Francisco CA 94117
Phone415-476-4684
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    Collapse Research 
    Collapse Research Activities and Funding
    Nonclinical development of Nervelight, an intra-operative peripheral nerve imaging agent
    NIH/NCI R44CA180745Sep 25, 2017 - Aug 31, 2019
    Role: Principal Investigator
    In vivo feasibility of a peripheral nerve imaging agent
    NIH/NCI R43CA180745Sep 1, 2013 - Feb 28, 2014
    Role: Principal Investigator
    Program for Development of BNCT Agents
    NIH/NCI R01CA082478Mar 1, 2000 - Jan 31, 2012
    Role: Principal Investigator
    DESIGN/SYNTHESIS OF BORONATED TUMOR-SEEKING MACROCYCLIC
    NIH/NCI R01CA053901Sep 18, 1991 - Jul 31, 1996
    Role: Principal Investigator
    BORONATED LIPOPROTEIN SITE SPECIFIC RADIOCHEMOTHERAPY
    NIH/NCI R01CA041487Jun 1, 1986 - May 31, 1990
    Role: Principal Investigator
    BORONATED TUMOR-SEEKING PORPHYRINS--SYNTHESIS &TESTING
    NIH/NCI R01CA037961Jul 1, 1985 - Nov 30, 1991
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Synthesis and comparative toxicology of a series of polyhedral borane anion-substituted tetraphenyl porphyrins. J Med Chem. 2007 Feb 22; 50(4):820-7. Koo MS, Ozawa T, Santos RA, Lamborn KR, Bollen AW, Deen DF, Kahl SB. PMID: 17253677.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    2. Simple, high-yield methods for the synthesis of aldehydes directly from o-, m-, and p-carborane and their further conversions. Inorg Chem. 2005 Oct 31; 44(22):8053-7. Dozzo P, Kasar RA, Kahl SB. PMID: 16241155.
      View in: PubMed   Mentions: 1     Fields:    
    3. Toxicity, biodistribution, and convection-enhanced delivery of the boronated porphyrin BOPP in the 9L intracerebral rat glioma model. Int J Radiat Oncol Biol Phys. 2005 Sep 01; 63(1):247-52. Ozawa T, Afzal J, Lamborn KR, Bollen AW, Bauer WF, Koo MS, Kahl SB, Deen DF. PMID: 16111595.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    4. Biodistribution of boron compounds in an animal model of human undifferentiated thyroid cancer for boron neutron capture therapy. Mol Pharm. 2005 Mar-Apr; 2(2):151-6. Dagrosa MA, Viaggi M, Rebagliati RJ, Batistoni D, Kahl SB, Juvenal GJ, Pisarev MA. PMID: 15804189.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    5. Synthesis, characterization, and plasma lipoprotein association of a nucleus-targeted boronated porphyrin. J Med Chem. 2005 Jan 27; 48(2):357-9. Dozzo P, Koo MS, Berger S, Forte TM, Kahl SB. PMID: 15658849.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    6. In vivo evaluation of the boronated porphyrin TABP-1 in U-87 MG intracerebral human glioblastoma xenografts. Mol Pharm. 2004 Sep-Oct; 1(5):368-74. Ozawa T, Santos RA, Lamborn KR, Bauer WF, Koo MS, Kahl SB, Deen DF. PMID: 16026007.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    7. Plasma pharmacokinetics and tissue biodistribution of boron following administration of a boronated porphyrin in dogs. J Pharm Sci. 2000 Apr; 89(4):469-77. Tibbitts J, Sambol NC, Fike JR, Bauer WF, Kahl SB. PMID: 10737908.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    8. Synthesis of 3-Amino-1-carboxy-o-carborane and an Improved, General Method for the Synthesis of All Three C-Amino-C-carboxycarboranes. Inorg Chem. 1999 Jun 14; 38(12):2936-2940. Kasar RA, Knudsen GM, Kahl SB. PMID: 11671041.
      View in: PubMed   Mentions: 4     Fields:    
    9. Toxicology of a boronated porphyrin in dogs. Photochem Photobiol. 1999 May; 69(5):587-94. Tibbitts J, Fike JR, Lamborn KR, Bollen AW, Kahl SB. PMID: 10333766.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    10. Enantioselective Synthesis of L- and D-Carboranylalanine. J Org Chem. 1996 Jul 12; 61(14):4582-4588. Radel PA, Kahl SB. PMID: 11667383.
      View in: PubMed   Mentions:    Fields:    
    11. Synthesis and Characterization of a Boronated Metallophthalocyanine for Boron Neutron Capture Therapy. Inorg Chem. 1996 Jun 19; 35(13):3878-3880. Kahl SB, Li J. PMID: 11666577.
      View in: PubMed   Mentions: 1     Fields:    
    12. Specific inhibition of HIV-1 protease by boronated porphyrins. J Med Chem. 1992 Sep 04; 35(18):3426-8. DeCamp DL, Babé LM, Salto R, Lucich JL, Koo MS, Kahl SB, Craik CS. PMID: 1527792.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    13. Uptake of a nido-carboranylporphyrin by human glioma xenografts in athymic nude mice and by syngeneic ovarian carcinomas in immunocompetent mice. Proc Natl Acad Sci U S A. 1990 Sep; 87(18):7265-9. Kahl SB, Joel DD, Nawrocky MM, Micca PL, Tran KP, Finkel GC, Slatkin DN. PMID: 2402507.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    14. Boronated porphyrins in NCT: results with a new potent tumor localizer. Strahlenther Onkol. 1989 Feb-Mar; 165(2-3):134-7. Kahl SB, Koo MS, Laster BH, Fairchild RG. PMID: 2928935.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    15. New tumor localizers: advances in the use of low density lipoproteins (LDL). Strahlenther Onkol. 1989 Feb-Mar; 165(2-3):137-9. Kahl SB, Callaway JC. PMID: 2928936.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. A carboranyl porphyrin for boron neutron capture therapy of brain tumors. Basic Life Sci. 1989; 50:193-203. Kahl SB, Joel DD, Finkel GC, Micca PL, Nawrocky MM, Coderre JA, Slatkin DN. PMID: 2751608.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    17. Distribution of a boronated porphyrin in murine tumors. Basic Life Sci. 1989; 50:205-12. Kahl SB, Laster BH, Koo MS, Warkentien LS, Fairchild RG. PMID: 2751609.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
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