Sugandh Kumar, PhD

Title(s)Postdoctoral Scholar, Dermatology
SchoolSchool of Medicine
Address2340 Sutter Street, #N431
San Francisco CA 94115
ORCID ORCID Icon0000-0001-7000-4718 Additional info
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    Institute of Life Sciences, Bhubaneswar, IndiaPh.D.2021Computational Biology

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    I have done Ph.D. in Bioinformatics from the Institute of Life Sciences in Bhubaneswar, India. My expertise revolves around high-resolution genomics, machine learning, and the discovery of novel molecules targeting diverse diseases. My current research focus at UCSF involves the in-depth analysis, integration, and exploration of T-cell regulatory mechanisms, utilizing Spatial and single-cell transcriptomics, BulkSeq, GWAS, and machine learning techniques. Also, I actively contribute to the design of innovative therapeutic compounds through computational drug design approaches, with a keen dedication to advancing our understanding of complex diseases and discovering novel treatments using various computational methodologies. I have collaboration with clinical fellows involves leveraging my biostatistics and machine-learning skills to establish meaningful associations between patient outcomes.

    Beyond the laboratory, I find joy in traveling, exploring new destinations, meeting diverse people, and engaging in outdoor activities such as hiking and biking. Additionally, I have a penchant for experimenting with various culinary delights.
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Natural products from Streptomyces spp. as potential inhibitors of the major factors (holoRdRp and nsp13) for SARS-CoV-2 replication: an in silico approach. Arch Microbiol. 2024 Feb 02; 206(2):88. Kumar P, Raj N, Kumar M, Fakhri KU, Kumar S, Khan AA, Alanazi AM, Solanki R, Manzoor N, Kapur MK. PMID: 38305873.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    2. Artificial Intelligence, Deep Learning, and Precision Medicine. Artificial Intelligence, Deep Learning, and Precision Medicine. 2023. Khalid Umar Fakhri, Sugandh Kumar, Md Zubbair Malik, Chirag N. Patel, Yogesh Kumar, Khalid Imtiyaz, Farhan Jalees Ahmad and M.Moshahid Alam Rizvi. View Publication.
    3. A partitioned 88-loci psoriasis genetic risk score reveals HLA and non-HLA contributions to clinical phenotypes in a Newfoundland psoriasis cohort. Front Genet. 2023; 14:1141010. Bui A, Kumar S, Liu J, Orcales F, Gulliver S, Tsoi LC, Gulliver W, Liao W. PMID: 37323656; PMCID: PMC10265743.
      View in: PubMed   Mentions: 1  
    4. Human sperm proteome reveals the effect of environmental borne seminal polyaromatic hydrocarbons exposome in etiology of idiopathic male factor infertility. Front Cell Dev Biol. 2023; 11:1117155. Nayak J, Jena SR, Kumar S, Kar S, Dixit A, Samanta L. PMID: 37261076; PMCID: PMC10228828.
      View in: PubMed   Mentions: 4  
    5. JEADV Clinical Practice. The association of hidradenitis suppurativa with obstructive sleep apnea: A cross-sectional study using the All of Us database. 2023. Samuel Yeroushalmi, Jared Liu, Mimi Chung, Kareem G. Elhage, Erin Bartholomew, Marwa Hakimi, Sugandh Kumar, Alexander Ildardashty, Haley B. Naik, Tina Bhutani, Wilson Liao. View Publication.
    6. Biologic insights from single-cell studies of psoriasis and psoriatic arthritis. Expert Opin Biol Ther. 2022 Nov 09; 1-13. Jin JQ, Wu D, Spencer R, Elhage KG, Liu J, Davis M, Hakimi M, Kumar S, Huang ZM, Bhutani T, Liao W. PMID: 36317702.
      View in: PubMed   Mentions: 1     Fields:    
    7. Factors Associated with Multi-Biologic Use in Psoriasis Patients at an Academic Medical Center and Review of Biologic Survival. Journal of Psoriasis and Psoriatic Arthritis. 2022; 8(1):1-8. Edward Hadeler, Sugandh Kumar, Samuel Yeroushalmi, Julie Hong, Elizabeth Wallace, George Han, Megan Mosca, Erin Bartholomew, Mimi Chung, Marwa Hakimi, Soumya Reddy, Jose Scher, Tina Bhutani, George Gondo, April Armstrong, Stacie Bell, and Wilson Liao. View Publication.
    8. TRPV1 channel in spermatozoa is a molecular target for ROS-mediated sperm dysfunction and differentially expressed in both natural and ART pregnancy failure. Front Cell Dev Biol. 2022; 10:867057. Swain N, Samanta L, Goswami C, Kar S, Majhi RK, Kumar S, Dixit A. PMID: 36211461; PMCID: PMC9538505.
      View in: PubMed   Mentions:
    9. Identification of therapeutically potential targets and their ligands for the treatment of OSCC. Front Oncol. 2022; 12:910494. Kumari P, Kumar S, Sethy M, Bhue S, Mohanta BK, Dixit A. PMID: 36203433; PMCID: PMC9530560.
      View in: PubMed   Mentions: 3  
    10. Comparative proteome profiling of seminal components reveal impaired immune cell signalling as paternal contributors in recurrent pregnancy loss patients. Am J Reprod Immunol. 2023 02; 89(2):e13613. Jena SR, Nayak J, Kumar S, Kar S, Samanta L. PMID: 35998016.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Hypoxia-responsive and HIF1α-regulated AAA+ ATPase ATAD2 shows high oncogenic potential in stomach cancer. Cancer Research. 2022; 86(12). A Roychowdhury, A Nayak, Sugandh Kumar, A Dixit, A Bhattacharyya. View Publication.
    12. Single Cell Transcriptome and Surface Epitope Analysis of Ankylosing Spondylitis Facilitates Disease Classification by Machine Learning. Front Immunol. 2022; 13:838636. Alber S, Kumar S, Liu J, Huang ZM, Paez D, Hong J, Chang HW, Bhutani T, Gensler LS, Liao W. PMID: 35634297; PMCID: PMC9135966.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    13. Association of seminal polyaromatic hydrocarbons exposome with idiopathic male factor infertility: A proteomic insight into sperm function. BioRxiv. 2022. Jasmine Nayak, Soumya Ranjan Jena, Sugandh Kumar, Anshuman Dixit, Luna Samanta . View Publication.
    14. Combined Single Cell Transcriptome and Surface Epitope Profiling Identifies Potential Biomarkers of Psoriatic Arthritis and Facilitates Diagnosis via Machine Learning. Front Immunol. 2022; 13:835760. Liu J, Kumar S, Hong J, Huang ZM, Paez D, Castillo M, Calvo M, Chang HW, Cummins DD, Chung M, Yeroushalmi S, Bartholomew E, Hakimi M, Ye CJ, Bhutani T, Matloubian M, Gensler LS, Liao W. PMID: 35309349; PMCID: PMC8924042.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    15. Nimbolide-encapsulated PLGA nanoparticles induces Mesenchymal-to-Epithelial Transition by dual inhibition of AKT and mTOR in pancreatic cancer stem cells. Toxicol In Vitro. 2022 Mar; 79:105293. Singh D, Mohapatra P, Kumar S, Behera S, Dixit A, Sahoo SK. PMID: 34883246.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    16. Correction: RRBP1 rewires cisplatin resistance in oral squamous cell carcinoma by regulating Hippo pathway. Br J Cancer. 2021 Jun; 124(12):2039. Shriwas O, Arya R, Mohanty S, Mohapatra P, Kumar S, Rath R, Kaushik SR, Pahwa F, Murmu KC, Das Majumdar SK, Muduly DK, Dixit A, Prasad P, Nanda RK, Dash R. PMID: 33963301; PMCID: PMC8184770.
      View in: PubMed   Mentions:    Fields:    
    17. Identification of multipotent drugs for COVID-19 therapeutics with the evaluation of their SARS-CoV2 inhibitory activity. Comput Struct Biotechnol J. 2021; 19:1998-2017. Kumar S, Singh B, Kumari P, Kumar PV, Agnihotri G, Khan S, Kant Beuria T, Syed GH, Dixit A. PMID: 33841751; PMCID: PMC8025584.
      View in: PubMed   Mentions: 23  
    18. RRBP1 rewires cisplatin resistance in oral squamous cell carcinoma by regulating Hippo pathway. Br J Cancer. 2021 06; 124(12):2004-2016. Shriwas O, Arya R, Mohanty S, Mohapatra P, Kumar S, Rath R, Kaushik SR, Pahwa F, Murmu KC, Majumdar SKD, Muduly DK, Dixit A, Prasad P, Nanda RK, Dash R. PMID: 33762722; PMCID: PMC8184829.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    19. Oncogenic potential of ATAD2 in stomach cancer and insights into the protein-protein interactions at its AAA + ATPase domain and bromodomain. J Biomol Struct Dyn. 2022 08; 40(12):5606-5622. Nayak A, Kumar S, Singh SP, Bhattacharyya A, Dixit A, Roychowdhury A. PMID: 33438526.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    20. Paternal contributors in recurrent pregnancy loss: Cues from comparative proteome profiling of seminal extracellular vesicles. Mol Reprod Dev. 2021 01; 88(1):96-112. Jena SR, Nayak J, Kumar S, Kar S, Dixit A, Samanta L. PMID: 33345401.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    21. Analysis of Indian SARS-CoV-2 Genomes Reveals Prevalence of D614G Mutation in Spike Protein Predicting an Increase in Interaction With TMPRSS2 and Virus Infectivity. Front Microbiol. 2020; 11:594928. Raghav S, Ghosh A, Turuk J, Kumar S, Jha A, Madhulika S, Priyadarshini M, Biswas VK, Shyamli PS, Singh B, Singh N, Singh D, Datey A, Avula K, Smita S, Sabat J, Bhattacharya D, Kshatri JS, Vasudevan D, Suryawanshi A, Dash R, Senapati S, Beuria TK, Swain R, Chattopadhyay S, Syed GH, Dixit A, Prasad P, Odisha COVID-19 Study Group, ILS COVID-19 Team, Pati S, Parida A. PMID: 33329480; PMCID: PMC7732478.
      View in: PubMed   Mentions: 33  
    22. Predictive models for stage and risk classification in head and neck squamous cell carcinoma (HNSCC). PeerJ. 2020; 8:e9656. Kumar S, Patnaik S, Dixit A. PMID: 33024622; PMCID: PMC7518185.
      View in: PubMed   Mentions: 6     Fields:    
    23. Identification of stage-wise miRNAs signature as a potential biomarker in head and neck squamous cell carcinoma. Clinical Cancer Research. 2020; 26(12). Sugandh Kumar, Anshuman Dixit. View Publication.
    24. Aberrant Upregulation of Compensatory Redox Molecular Machines May Contribute to Sperm Dysfunction in Infertile Men with Unilateral Varicocele: A Proteomic Insight. Antioxid Redox Signal. 2020 03 10; 32(8):504-521. Swain N, Samanta L, Agarwal A, Kumar S, Dixit A, Gopalan B, Durairajanayagam D, Sharma R, Pushparaj PN, Baskaran S. PMID: 31691576.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
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