Svetlana Kholodar, PhD

Title(s)Postdoctoral Scholar, Pharmaceutical Chemistry
SchoolSchool of Pharmacy
Address600 16th St
San Francisco CA 94158
ORCID ORCID Icon0000-0002-4100-1814 Additional info
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Analogs of the Dopamine Metabolite 5,6-Dihydroxyindole Bind Directly to and Activate the Nuclear Receptor Nurr1. ACS Chem Biol. 2021 07 16; 16(7):1159-1163. Kholodar SA, Lang G, Cortopassi WA, Iizuka Y, Brah HS, Jacobson MP, England PM. PMID: 34165961.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate Analog. Biochemistry. 2021 04 27; 60(16):1243-1247. Kholodar SA, Finer-Moore JS, Swiderek K, Arafet K, Moliner V, Stroud RM, Kohen A. PMID: 33829766.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    3. Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite. Cell Chem Biol. 2019 05 16; 26(5):674-685.e6. Bruning JM, Wang Y, Oltrabella F, Tian B, Kholodar SA, Liu H, Bhattacharya P, Guo S, Holton JM, Fletterick RJ, Jacobson MP, England PM. PMID: 30853418.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    4. Parallel reaction pathways and noncovalent intermediates in thymidylate synthase revealed by experimental and computational tools. Proc Natl Acad Sci U S A. 2018 10 09; 115(41):10311-10314. Kholodar SA, Ghosh AK, Swiderek K, Moliner V, Kohen A. PMID: 30249644.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    5. Measurement of Enzyme Isotope Effects. Methods Enzymol. 2017; 596:43-83. Kholodar SA, Ghosh AK, Kohen A. PMID: 28911779.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    6. Noncovalent Intermediate of Thymidylate Synthase: Fact or Fiction? J Am Chem Soc. 2016 07 06; 138(26):8056-9. Kholodar SA, Kohen A. PMID: 27327197.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    7. The role of phosphate in a multistep enzymatic reaction: reactions of the substrate and intermediate in pieces. J Am Chem Soc. 2015 Feb 25; 137(7):2748-56. Kholodar SA, Allen CL, Gulick AM, Murkin AS. PMID: 25642788.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    8. Mechanism and inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase. Bioorg Chem. 2014 Dec; 57:171-185. Murkin AS, Manning KA, Kholodar SA. PMID: 24998420.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    9. Alteration of the flexible loop in 1-deoxy-D-xylulose-5-phosphate reductoisomerase boosts enthalpy-driven inhibition by fosmidomycin. Biochemistry. 2014 Jun 03; 53(21):3423-31. Kholodar SA, Tombline G, Liu J, Tan Z, Allen CL, Gulick AM, Murkin AS. PMID: 24825256.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    10. Multipyrene tandem probes for point mutations detection in DNA. J Nucleic Acids. 2013; 2013:860457. Kholodar SA, Novopashina DS, Meschaninova MI, Venyaminova AG. PMID: 24455205.
      View in: PubMed   Mentions:
    11. DXP reductoisomerase: reaction of the substrate in pieces reveals a catalytic role for the nonreacting phosphodianion group. Biochemistry. 2013 Apr 02; 52(13):2302-8. Kholodar SA, Murkin AS. PMID: 23473304.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    12. Multipyrene tandem probes for detection of C677T polymorphism in MTHFR gene. Nucleic Acids Symp Ser (Oxf). 2009; (53):143-4. Kholodar SA, Novopashina DS, Meschaninova MI, Lomzov AA, Venyaminova AG. PMID: 19749301.
      View in: PubMed   Mentions: 2     Fields:    
    13. Oligo(2'-O-methylribonucleotides) and their derivatives: III. 5'-Mono- and 5'-bispyrenyl derivatives of oligo(2'-O-methylribonucleotides) and their 3'-modified analogues: Synthesis and properties. Russian Journal of Bioorganic Chemistry. 2008 Sep 1; 34(5):602. Novopashina ND, Totskaya TO, Kholodar’ KS, Meshchaninova MM, Ven’yaminova VA. .
      View in: Publisher Site   Mentions:
    14. New eximer-based tandem systems for SNP detection. Nucleic Acids Symp Ser (Oxf). 2008; (52):229-30. Novopashina DS, Meschaninova MI, Kholodar SA, Lomzov AA, Venyaminova AG. PMID: 18776337.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
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