Svetlana Kholodar, PhD

Title(s)Postdoctoral Scholar, Pharmaceutical Chemistry
SchoolSchool of Pharmacy
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bruning JM, Wang Y, Oltrabella F, Tian B, Kholodar SA, Liu H, Bhattacharya P, Guo S, Holton JM, Fletterick RJ, Jacobson MP, England PM. Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite. Cell Chem Biol. 2019 Feb 16. PMID: 30853418.
      View in: PubMed
    2. Kholodar SA, Ghosh AK, Swiderek K, Moliner V, Kohen A. Parallel reaction pathways and noncovalent intermediates in thymidylate synthase revealed by experimental and computational tools. Proc Natl Acad Sci U S A. 2018 10 09; 115(41):10311-10314. PMID: 30249644.
      View in: PubMed
    3. Kholodar SA, Ghosh AK, Kohen A. Measurement of Enzyme Isotope Effects. Methods Enzymol. 2017; 596:43-83. PMID: 28911779.
      View in: PubMed
    4. Kholodar SA, Kohen A. Noncovalent Intermediate of Thymidylate Synthase: Fact or Fiction? J Am Chem Soc. 2016 07 06; 138(26):8056-9. PMID: 27327197.
      View in: PubMed
    5. Kholodar SA, Allen CL, Gulick AM, Murkin AS. The role of phosphate in a multistep enzymatic reaction: reactions of the substrate and intermediate in pieces. J Am Chem Soc. 2015 Feb 25; 137(7):2748-56. PMID: 25642788; PMCID: PMC4507815.
    6. Murkin AS, Manning KA, Kholodar SA. Mechanism and inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase. Bioorg Chem. 2014 Dec; 57:171-85. PMID: 24998420.
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    7. Kholodar SA, Tombline G, Liu J, Tan Z, Allen CL, Gulick AM, Murkin AS. Alteration of the flexible loop in 1-deoxy-D-xylulose-5-phosphate reductoisomerase boosts enthalpy-driven inhibition by fosmidomycin. Biochemistry. 2014 Jun 03; 53(21):3423-31. PMID: 24825256; PMCID: PMC4045324.
    8. Kholodar SA, Novopashina DS, Meschaninova MI, Venyaminova AG. Multipyrene tandem probes for point mutations detection in DNA. J Nucleic Acids. 2013; 2013:860457. PMID: 24455205; PMCID: PMC3886547.
    9. Kholodar SA, Murkin AS. DXP reductoisomerase: reaction of the substrate in pieces reveals a catalytic role for the nonreacting phosphodianion group. Biochemistry. 2013 Apr 02; 52(13):2302-8. PMID: 23473304.
      View in: PubMed
    10. Kholodar SA, Novopashina DS, Meschaninova MI, Lomzov AA, Venyaminova AG. Multipyrene tandem probes for detection of C677T polymorphism in MTHFR gene. Nucleic Acids Symp Ser (Oxf). 2009; (53):143-4. PMID: 19749301.
      View in: PubMed
    11. Novopashina DS, Meschaninova MI, Kholodar SA, Lomzov AA, Venyaminova AG. New eximer-based tandem systems for SNP detection. Nucleic Acids Symp Ser (Oxf). 2008; (52):229-30. PMID: 18776337.
      View in: PubMed