Swetansu Hota, PhD

Title(s)Scientist, Business Service Ctr
SchoolChancellor/EVC/FAS
Phone--
ORCID ORCID Icon0000-0003-3105-9729 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Gladstone Institutes, San FranciscoPostdocDevelopmental Biology, Genomics, Biochemistry
    Southern Illinois University, CarbondalePhD2011Biochemistry
    Collapse Awards and Honors
    Gladstone Institutes2020Distinguished Achievement in Science Award
    UCSF/CVRI2018Poster Prize
    Gladstone Institutes2018Career Advancement Award
    Innocentive.com2003Solver award
    AstraZeneca2002Initiative Award

    Collapse Research 
    Collapse Research Activities and Funding
    Dissecting the function of BAF chromatin remodeling ATPases during cardiogenesis
    American Heart Association 861914, Career Development AwardJul 1, 2021 - Jun 30, 2024
    Role: Principal Investigator
    Dissecting the functions of cardiac specific BAF complexes in cardiac gene regulation
    NIH 4T32HL007731-25, T32Jul 14, 2017 - Jul 13, 2018
    Role: Trainee
    Chromatin remodellers Brg1 and Baf60c in heart development
    Tobacco Related Disease Research Program 22FT-0079, Post-doctoralAug 1, 2015 - Jul 31, 2016
    Role: Principal Investigator
    Molecular and genomic function of the chromatin remodeling factor Baf60c in heart development
    American Heart Association 13POST17290043, Post-doctoral (declined)Jul 1, 2013 - Jun 30, 2015
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Brahma safeguards canalization of cardiac mesoderm differentiation. Nature. 2022 02; 602(7895):129-134. Hota SK, Rao KS, Blair AP, Khalilimeybodi A, Hu KM, Thomas R, So K, Kameswaran V, Xu J, Polacco BJ, Desai RV, Chatterjee N, Hsu A, Muncie JM, Blotnick AM, Winchester SAB, Weinberger LS, Hüttenhain R, Kathiriya IS, Krogan NJ, Saucerman JJ, Bruneau BG. PMID: 35082446.
      View in: PubMed   Mentions:
    2. Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease. Dev Cell. 2021 02 08; 56(3):292-309.e9. Kathiriya IS, Rao KS, Iacono G, Devine WP, Blair AP, Hota SK, Lai MH, Garay BI, Thomas R, Gong HZ, Wasson LK, Goyal P, Sukonnik T, Hu KM, Akgun GA, Bernard LD, Akerberg BN, Gu F, Li K, Speir ML, Haeussler M, Pu WT, Stuart JM, Seidman CE, Seidman JG, Heyn H, Bruneau BG. PMID: 33321106; PMCID: PMC7878434.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    3. Dinucleosome specificity and allosteric switch of the ISW1a ATP-dependent chromatin remodeler in transcription regulation. Nat Commun. 2020 11 20; 11(1):5913. Bhardwaj SK, Hailu SG, Olufemi L, Brahma S, Kundu S, Hota SK, Persinger J, Bartholomew B. PMID: 33219211; PMCID: PMC7680125.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    4. Dynamic BAF chromatin remodeling complex subunit inclusion promotes temporally distinct gene expression programs in cardiogenesis. Development. 2019 07 05; 146(19). Hota SK, Johnson JR, Verschueren E, Thomas R, Blotnick AM, Zhu Y, Sun X, Pennacchio LA, Krogan NJ, Bruneau BG. PMID: 30814119; PMCID: PMC6803373.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    5. Histone Octamer Structure Is Altered Early in ISW2 ATP-Dependent Nucleosome Remodeling. Cell Rep. 2019 07 02; 28(1):282-294.e6. Hada A, Hota SK, Luo J, Lin YC, Kale S, Shaytan AK, Bhardwaj SK, Persinger J, Ranish J, Panchenko AR, Bartholomew B. PMID: 31269447.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    6. Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function. Biol Open. 2018 Jan 05; 7(1). Sun X, Hota SK, Zhou YQ, Novak S, Miguel-Perez D, Christodoulou D, Seidman CE, Seidman JG, Gregorio CC, Henkelman RM, Rossant J, Bruneau BG. PMID: 29183906; PMCID: PMC5829499.
      View in: PubMed   Mentions: 13  
    7. ATP-dependent chromatin remodeling during mammalian development. Development. 2016 08 15; 143(16):2882-97. Hota SK, Bruneau BG. PMID: 27531948; PMCID: PMC5004879.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    8. Brg1 modulates enhancer activation in mesoderm lineage commitment. Development. 2015 Apr 15; 142(8):1418-30. Alexander JM, Hota SK, He D, Thomas S, Ho L, Pennacchio LA, Bruneau BG. PMID: 25813539; PMCID: PMC4392595.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    9. ISWI remodelers slide nucleosomes with coordinated multi-base-pair entry steps and single-base-pair exit steps. Cell. 2013 Jan 31; 152(3):442-52. Deindl S, Hwang WL, Hota SK, Blosser TR, Prasad P, Bartholomew B, Zhuang X. PMID: 23374341; PMCID: PMC3647478.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    10. Nucleosome mobilization by ISW2 requires the concerted action of the ATPase and SLIDE domains. Nat Struct Mol Biol. 2013 Feb; 20(2):222-9. Hota SK, Bhardwaj SK, Deindl S, Lin YC, Zhuang X, Bartholomew B. PMID: 23334290; PMCID: PMC3565048.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    11. Disparity in the DNA translocase domains of SWI/SNF and ISW2. Nucleic Acids Res. 2012 May; 40(10):4412-21. Dechassa ML, Hota SK, Sen P, Chatterjee N, Prasad P, Bartholomew B. PMID: 22298509; PMCID: PMC3378860.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    12. Mapping protein-DNA and protein-protein interactions of ATP-dependent chromatin remodelers. Methods Mol Biol. 2012; 809:381-409. Hota SK, Dechassa ML, Prasad P, Bartholomew B. PMID: 22113290.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    13. Approaches for studying nucleosome movement by ATP-dependent chromatin remodeling complexes. Methods Mol Biol. 2012; 809:367-80. Hota SK, Bartholomew B. PMID: 22113289.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    14. An assay for exogenous sources of purified MurG, enabled by the complementation of Escherichia coli murG(Ts) by the Mycobacterium tuberculosis homologue. FEMS Microbiol Lett. 2012 Jan; 326(2):161-7. Jha RK, Katagihallimath N, Hota SK, Das KS, de Sousa SM. PMID: 22092490.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    15. Diversity of operation in ATP-dependent chromatin remodelers. Biochim Biophys Acta. 2011 Sep; 1809(9):476-87. Hota SK, Bartholomew B. PMID: 21616185; PMCID: PMC3171594.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells