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CNSC-65. ELECTROPHYSIOLOGICAL AND SPATIAL TRANSCRIPTOMIC PROFILING OF GLIOMA-INFILTRATED CORTEX REVEAL LAYER SPECIFIC ALTERATIONS. Neuro-Oncology. 2024 Nov 11; 26(Supplement_8):viii55-viii56.
Daniel DA, Aabedi AA, Umbach UG, Negussi NM, Herr HS, Gonzales GC, Krishna KS, Kaur KJ, Fazzari FE, Nejo NT, Raleigh RD, Bhaduri BA, Joseph JK, Ravi RV, Brang BD, Hervey-Jumper HS. .
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IMMU-28. LOW-INTENSITY PULSED ULTRASOUND COMBINED WITH POLY-ICLC AND INTERLEUKIN-2 UNLOCKS THE IMMUNE PRIVILEGE OF THE BRAIN BY PROMOTING EPITOPE SPREADING AND ACTIVATION OF CNS-SPECIFIC NAÏVE T CELLS. Neuro-Oncology. 2024 Nov 11; 26(Supplement_8):viii158-viii158.
Gallus GM, Yamamichi YA, Arrieta AV, Saijo SA, Chuntova CP, Phyu PS, Phung PL, Haegelin HJ, Long LH, Lakshmanachetty LS, Nejo NT, Okada OK, Chen CL, Habashy HK, Gould GA, Amidei AC, Chang CC, Stupp SR, Canney CM, Sonabend SA, Okada OH. .
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IMMU-55. TUMOR-WIDE RNA SPLICING ABERRATIONS GENERATE IMMUNOGENIC PUBLIC NEOANTIGENS IN GLIOBLASTOMAS AND OTHER CANCER TYPES. Neuro-Oncology. 2024 Nov 11; 26(Supplement_8):viii165-viii165.
Kwok KD, Stevers SN, Etxeberria EI, Nejo NT, Cove CM, Chen CL, Jung JJ, Okada OK, Lakshmanachetty LS, Gallus GM, Barpanda BA, Hong HC, Chan CG, Liu LJ, Wu WS, Ramos RE, Yamamichi YA, Watchmaker WP, Ogino OH, Saijo SA, Du DA, Grishanina GN, Woo WJ, Diaz DA, Chang CS, Phillips PJ, Wiita WA, Klebanoff KC, Costello CJ, Okada OH. .
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P02.16.A IRF8-DRIVEN REPROGRAMMING OF THE IMMUNE MICROENVIRONMENT ENHANCES ANTI-TUMOR ADAPTIVE IMMUNITY AND REDUCES IMMUNOSUPPRESSION IN MURINE GLIOBLASTOMA. Neuro-Oncology. 2024 Oct 17; 26(Supplement_5):v38-v38.
Montoya MM, Collins CS, Chuntova CP, Patel PT, Nejo NT, Yamamichi YA, Kasahara KN, Okada OH. .
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KS05.6.A T-CELL THERAPY COMBINED WITH LOW-INTENSITY PULSED FOCUSED ULTRASOUND, MICROBUBBLES AND POLY-ICLC PROMOTES THE PRESENTATION OF BRAIN-DERIVED ANTIGENS, BREAKING CNS TOLERANCE AND INDUCING ACTIVE T-CELL RESPONSES. Neuro-Oncology. 2024 Oct 17; 26(Supplement_5):v7-v8.
Gallus GM, Yamamichi YA, Arrieta AV, Saijo SA, Chuntova CP, Haegelin HJ, Phyu PS, Phung PL, Long LJ, Lakshmanachetty LS, Nejo NT, Okada OK, Chen CL, Habashy HK, Gould GA, Amidei AC, Chang CC, Stupp SR, Canney CM, Sonabend SA, Okada OH. .
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IRF8-driven reprogramming of the immune microenvironment enhances anti-tumor adaptive immunity and reduces immunosuppression in murine glioblastoma. Neuro Oncol. 2024 Aug 08.
Montoya M, Collins SA, Chuntova P, Patel TS, Nejo T, Yamamichi A, Kasahara N, Okada H. PMID: 39115195.
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Lessons from Post-Immunotherapy Tumor Tissues in Clinical Trials: How Can We Fuel the Tumor Microenvironment in Gliomas? Vaccines (Basel). 2024 Aug 01; 12(8).
Phung LH, Nejo T, Okada H. PMID: 39203988; PMCID: PMC11359082.
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AB019. Detailed analysis of DNA hydroxymethylation observed with the malignant progression of IDH-mutant gliomas. Chin Clin Oncol. 2024 Aug; 13(Suppl 1):AB019.
Hana T, Mukasa A, Nomura M, Nagae G, Yamamoto S, Tatsuno K, Ueda H, Fukuda S, Umeda T, Tanaka S, Nejo T, Kitagawa Y, Yamazawa E, Takahashi S, Koike T, Kushihara Y, Takami H, Takayanagi S, Aburatani H, Saito N. PMID: 39295337.
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Translation:
HumansCells
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Enhancing CAR-T cell metabolism to overcome hypoxic conditions in the brain tumor microenvironment. JCI Insight. 2024 Apr 08; 9(7).
Hatae R, Kyewalabye K, Yamamichi A, Chen T, Phyu S, Chuntova P, Nejo T, Levine LS, Spitzer MH, Okada H. PMID: 38386420; PMCID: PMC11128202.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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IRF8-driven reprogramming of the immune microenvironment enhances anti-tumor adaptive immunity and reduces immunosuppression in murine glioblastoma. bioRxiv. 2024 Apr 03.
Montoya M, Collins SA, Chuntova P, Patel TS, Nejo T, Yamamichi A, Kasahara N, Okada H. PMID: 38617245; PMCID: PMC11014587.
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Abstract 3907: Novel public and tumor-wide neoantigens arising from clonal aberrant splicing events drive tumor-specific T-cell responses across diverse cancer types. Cancer Research. 2024 Mar 22; 84(6_Supplement):3907-3907.
Kwok KD, Stevers SN, Nejo NT, Chen CL, Etxeberria EI, Jung JJ, Okada OK, Cove CM, Lakshmanachetty LS, Gallus GM, Barpanda BA, Hong HC, Chan CG, Wu WS, Ramos RE, Yamamichi YA, Liu LJ, Watchmaker WP, Ogino OH, Saijo SA, Du DA, Grishanina GN, Woo WJ, Diaz DA, Chang CS, Phillips PJ, Wiita WA, Klebanoff KC, Costello CJ, Okada OH. .
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Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma. Sci Rep. 2024 03 16; 14(1):6362.
Nejo T, Wang L, Leung KK, Wang A, Lakshmanachetty S, Gallus M, Kwok DW, Hong C, Chen LH, Carrera DA, Zhang MY, Stevers NO, Maldonado GC, Yamamichi A, Watchmaker PB, Naik A, Shai A, Phillips JJ, Chang SM, Wiita AP, Wells JA, Costello JF, Diaz AA, Okada H. PMID: 38493204; PMCID: PMC10944514.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Region-specific DNA hydroxymethylation along the malignant progression of IDH-mutant gliomas. Cancer Sci. 2024 May; 115(5):1706-1717.
Hana T, Mukasa A, Nomura M, Nagae G, Yamamoto S, Tatsuno K, Ueda H, Fukuda S, Umeda T, Tanaka S, Nejo T, Kitagawa Y, Yamazawa E, Takahashi S, Koike T, Kushihara Y, Takami H, Takayanagi S, Aburatani H, Saito N. PMID: 38433527; PMCID: PMC11093199.
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1 Fields:
Translation:
HumansCells
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Glioblastoma with high O6-methyl-guanine DNA methyltransferase expression are more immunologically active than tumors with low MGMT expression. Front Immunol. 2024; 15:1328375.
Kushihara Y, Tanaka S, Kobayashi Y, Nagaoka K, Kikuchi M, Nejo T, Yamazawa E, Nambu S, Kugasawa K, Takami H, Takayanagi S, Saito N, Kakimi K. PMID: 38288307; PMCID: PMC10824125.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Enhancing CAR-T Cell Metabolism to Overcome Hypoxic Conditions in the Brain Tumor Microenvironment. bioRxiv. 2023 Nov 15.
Hatae R, Kyewalabye K, Yamamichi A, Chen T, Phyu S, Chuntova P, Nejo T, Levine LS, Spitzer MH, Okada H. PMID: 38014236; PMCID: PMC10680638.
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CNSC-06. REDIRECTING IMMUNOSUPPRESSIVE GLIOMA MICROENVIRONMENT THROUGH PHARMACOLOGICAL INTERVENTION TARGETING NEURONAL ACTIVITY. Neuro-Oncology. 2023 Nov 10; 25(Supplement_5):v23-v23.
Nejo NT, Krishna KS, Yamamichi YA, Jimenez JC, Lakshmanachetty LS, Young YJ, Phyu PS, Watchmaker WP, Hervey-Jumper HS, Okada OH. .
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IMMU-16. PUBLIC TUMOR-WIDE NEOANTIGENS DERIVED FROM CLONAL ABERRANT SPLICING EVENTS DRIVE TUMOR-SPECIFIC T-CELL RESPONSES. Neuro-Oncology. 2023 Nov 10; 25(Supplement_5):v144-v145.
Kwok KD, Stevers SN, Nejo NT, Jung JJ, Chen CL, Lakshmanachetty LS, Etxeberria EI, Gallus GM, Yamamichi YA, Ramos RE, Hong HC, Colton CM, Chan CG, Du DA, Woo WJ, Wiita WA, Klebanoff KC, Costello CJ, Okada OH. .
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Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma. bioRxiv. 2023 Nov 02.
Nejo T, Wang L, Leung KK, Wang A, Lakshmanachetty S, Gallus M, Kwok DW, Hong C, Chen LH, Carrera DA, Zhang MY, Stevers NO, Maldonado GC, Yamamichi A, Watchmaker P, Naik A, Shai A, Phillips JJ, Chang SM, Wiita AP, Wells JA, Costello JF, Diaz AA, Okada H. PMID: 37961484; PMCID: PMC10634890.
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2
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Tumor-wide RNA splicing aberrations generate immunogenic public neoantigens. bioRxiv. 2023 Oct 20.
Kwok DW, Stevers NO, Nejo T, Chen LH, Etxeberria I, Jung J, Okada K, Cove MC, Lakshmanachetty S, Gallus M, Barpanda A, Hong C, Chan GKL, Wu SH, Ramos E, Yamamichi A, Liu J, Watchmaker P, Ogino H, Saijo A, Du A, Grishanina N, Woo J, Diaz A, Chang SM, Phillips JJ, Wiita AP, Klebanoff CA, Costello JF, Okada H. PMID: 37904942; PMCID: PMC10614978.
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Glioma-neuronal circuit remodeling induces regional immunosuppression. bioRxiv. 2023 Aug 06.
Nejo T, Krishna S, Jimenez C, Yamamichi A, Young JS, Lakshmanachetty S, Chen T, Phyu SSS, Ogino H, Watchmaker P, Diebold D, Choudhury A, Daniel AGS, Raleigh DR, Hervey-Jumper SL, Okada H. PMID: 37577659; PMCID: PMC10418167.
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Abstract 2497: Glioma-induced neuronal remodeling promotes regional immunosuppression. Cancer Research. 2023 Apr 4; 83(7_Supplement):2497-2497.
Nejo NT, Krishna KS, Jimenez JC, Yamamichi YA, Young YJ, Chen CT, Lakshmanachetty LS, Watchmaker WP, Choudhury CA, Ogino OH, Raleigh RD, Hervey-Jumper HS, Okada OH. .
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Abstract 3152: Targetable public neoantigens are generated by tumor-wide cancer-specific splicing events in gliomas. Cancer Research. 2023 Apr 4; 83(7_Supplement):3152-3152.
Kwok KD, Nejo NT, Stevers SN, Chen CL, Okada OK, Hong HC, Chan CG, Yamamichi YA, Du DA, Colton CM, Woo WJ, Costello CJ, Okada OH. .
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CNSC-19. GLIOMA-INDUCED NEURONAL REMODELING PROMOTES REGIONAL IMMUNOSUPPRESSION. Neuro-Oncology. 2022 Nov 14; 24(Supplement_7):vii26-vii26.
Nejo NT, Krishna KS, Young YJ, Yamamichi YA, Jimenez JC, Chen CT, Watchmaker WP, Choudhury CA, Diebold DD, Ogino OH, Raleigh RD, Hervey-Jumper HS, Okada OH. .
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Primary Intracranial Spindle Cell Sarcoma, DICER1-Mutant, with MDM2 Amplification Diagnosed on the Basis of Extensive Molecular Profiling. Clin Med Insights Case Rep. 2022; 15:11795476221131189.
Nejo T, Takayanagi S, Tanaka S, Shinozaki-Ushiku A, Kohsaka S, Nagata K, Yokoyama M, Sora S, Ushiku T, Mukasa A, Aburatani H, Mano H, Saito N. PMID: 36277904; PMCID: PMC9580084.
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4
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Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma. J Clin Invest. 2022 Jun 15; 132(12).
Mueller S, Taitt JM, Villanueva-Meyer JE, Bonner ER, Nejo T, Lulla RR, Goldman S, Banerjee A, Chi SN, Whipple NS, Crawford JR, Gauvain K, Nazemi KJ, Watchmaker PB, Almeida ND, Okada K, Salazar AM, Gilbert RD, Nazarian J, Molinaro AM, Butterfield LH, Prados MD, Okada H. PMID: 35703183; PMCID: PMC9203080.
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3 Fields:
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Abstract 4170: Integrative transcriptomic and proteomic analysis reveals immunogenic and spatially-conserved HLA-binding neoantigen targets derived from tumor-specific alternative splicing events. Cancer Research. 2022 Jun 15; 82(12_Supplement):4170-4170.
Kwok KD, Nejo NT, Du DA, Colton CM, Woo WJ, Costello CJ, Okada OH. .
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Inhibition of D-2HG leads to upregulation of a proinflammatory gene signature in a novel HLA-A2/HLA-DR1 transgenic mouse model of IDH1R132H-expressing glioma. J Immunother Cancer. 2022 05; 10(5).
Chuntova P, Yamamichi A, Chen T, Narayanaswamy R, Ronseaux S, Hudson C, Tron AE, Hyer ML, Montoya M, Mende AL, Nejo T, Downey KM, Diebold D, Lu M, Nicolay B, Okada H. PMID: 35606087; PMCID: PMC9174833.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Randomized trial of neoadjuvant vaccination with tumor-cell lysate induces T cell response in low-grade gliomas. J Clin Invest. 2022 02 01; 132(3).
Ogino H, Taylor JW, Nejo T, Gibson D, Watchmaker PB, Okada K, Saijo A, Tedesco MR, Shai A, Wong CM, Rabbitt JE, Olin MR, Moertel CL, Nishioka Y, Salazar AM, Molinaro AM, Phillips JJ, Butowski NA, Clarke JL, Oberheim Bush NA, Hervey-Jumper SL, Theodosopoulos P, Chang SM, Berger MS, Okada H. PMID: 34882581; PMCID: PMC8803342.
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PubMed Mentions:
21 Fields:
Translation:
HumansCellsPHPublic Health
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Novel EGFRvIII-CAR transgenic mice for rigorous preclinical studies in syngeneic mice. Neuro Oncol. 2022 02 01; 24(2):259-272.
Chuntova P, Hou Y, Naka R, Yamamichi A, Chen T, Goretsky Y, Hatae R, Nejo T, Kohanbash G, Mende AL, Montoya M, Downey KM, Diebold D, Skinner J, Liang HE, Schwer B, Okada H. PMID: 34347086; PMCID: PMC8804899.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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EPCO-14. MULTIFACETED TRANSCRIPTOMIC AND PROTEOMIC ANALYSES IDENTIFIED PUTATIVE ALTERNATIVE SPLICING-DERIVED CELL SURFACE ANTIGENS IN GLIOMA. Neuro-Oncology. 2021 Nov 12; 23(Supplement_6):vi4-vi4.
Nejo NT, Kwok KD, Leung LK, Wang WL, Wang WA, Watchmaker WP, Diebold DD, Driks DH, Wells WJ, Diaz DA, Costello CJ, Okada OH. .
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IMMU-31. TUMOR-SPECIFIC ALTERNATIVE SPLICING GENERATES SPATIALLY-CONSERVED HLA-BINDING NEOANTIGEN TARGETS DETECTED THROUGH INTEGRATIVE TRANSCRIPTOMIC AND PROTEOMIC ANALYSES. Neuro-Oncology. 2021 Nov 12; 23(Supplement_6):vi99-vi99.
Kwok KD, Nejo NT, Costello CJ, Okada OH. .
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SURG-10. DEVELOPMENT OF NOVEL TOPICAL FLUORESCENT PROBE FOR INTRAOPERATIVE RAPID DETECTION OF GLIOMA. Neuro-Oncology. 2021 Nov 12; 23(Supplement_6):vi197-vi197.
Tanaka TS, Kitagawa KY, Kamiya KM, Kuriki KY, Yamamoto YK, Shimizu ST, Nejo NT, Hana HT, Koike KT, Yamazawa YE, Kushihara KY, Takahashi TS, Nomura NM, Takami TH, Takayanagi TS, Mukasa MA, Urano UY, Saito SN. .
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CTIM-24. RANDOMIZED TRIAL OF NEOADJUVANT VACCINATION WITH TUMOR-CELL LYSATE INDUCES T CELL RESPONSE IN LOW-GRADE GLIOMAS. Neuro-Oncology. 2021 Nov 12; 23(Supplement_6):vi55-vi55.
Taylor TJ, Ogino OH, Nejo NT, Gibson GD, Watchmaker WP, Okada OK, Saijo SA, Tedesco TM, Shai SA, Wong WC, Rabbitt RJ, Olin OM, Moertel MC, Nishioka NY, Salazar SA, Molinaro MA, Phillips PJ, Butowski BN, Clarke CJ, Oberheim-Bush ON, Hervey-Jumper HS, Theodosopoulos TP, Chang CS, Berger BM, Okada OH. .
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IMMU-33. NEOANTIGEN-SPECIFIC T CELLS CAN INFILTRATE IDH-MUTANT LOWER GRADE GLIOMAS AND PERSIST IN THE PERIPHERAL BLOOD. Neuro-Oncology. 2021 Nov 12; 23(Supplement_6):vi99-vi100.
Zhang ZM, Wang WC, Pan PZ, Yuen YB, Peng PS, Kwok KD, Nejo NT, Martin MM, Hong HC, Hilz HS, Phillips PJ, Shai SA, Oberheim-Bush ON, Hervey-Jumper HS, McDermott MM, Mandl MS, Okada OH, Costello CJ. .
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A Novel Topical Fluorescent Probe for Detection of Glioblastoma. Clin Cancer Res. 2021 07 15; 27(14):3936-3947.
Kitagawa Y, Tanaka S, Kamiya M, Kuriki Y, Yamamoto K, Shimizu T, Nejo T, Hana T, Matsuura R, Koike T, Yamazawa E, Kushihara Y, Takahashi S, Nomura M, Takami H, Takayanagi S, Mukasa A, Urano Y, Saito N. PMID: 34031057.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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The evolution of alternative splicing in glioblastoma under therapy. Genome Biol. 2021 01 26; 22(1):48.
Wang L, Shamardani K, Babikir H, Catalan F, Nejo T, Chang S, Phillips JJ, Okada H, Diaz AA. PMID: 33499924; PMCID: PMC7835670.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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IMMU-31. PNOC007: H3.3K27M SPECIFIC PEPTIDE VACCINE COMBINED WITH POLY-ICLC FOR THE TREATMENT OF NEWLY DIAGNOSED HLA-A2+ H3.3K27M DIFFUSE MIDLINE GLIOMAS (DMG). Neuro-Oncology. 2020 Dec 4; 22(Suppl 3):iii366-iii366.
Mueller MS, Taitt TJ, Bonner BE, Lulla LR, Goldman GS, Banerjee BA, Chi CS, Whipple WN, Crawford CJ, Gauvain GK, Nazemi NK, Watchmaker WP, Nejo NT, Okada OK, Butterfield BL, Nazarian NJ, Villaneuva-Meyer VJ, Molinaro MA, Prados PM, Okada OH. .
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IMMU-23. A NOVEL MASS CYTOMETRY-BASED MULTI-PARAMETER CHARACTERIZATION OF NEOANTIGEN-REACTIVE CD8+ T-CELLS IN PATIENTS PARTICIPATING IN PNOC007 H3.3K27M PEPTIDE VACCINE CLINICAL TRIAL. Neuro-Oncology. 2020 Dec 4; 22(Suppl 3):iii364-iii365.
Taitt TJ, Nejo NT, Watchmaker WP, Almeida AN, Okada OK, Shahin SM, Gilbert GR, Molinaro MA, Prados PM, Mueller MS, Okada OH. .
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Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma. J Clin Invest. 2020 12 01; 130(12):6325-6337.
Mueller S, Taitt JM, Villanueva-Meyer JE, Bonner ER, Nejo T, Lulla RR, Goldman S, Banerjee A, Chi SN, Whipple NS, Crawford JR, Gauvain K, Nazemi KJ, Watchmaker PB, Almeida ND, Okada K, Salazar AM, Gilbert RD, Nazarian J, Molinaro AM, Butterfield LH, Prados MD, Okada H. PMID: 32817593; PMCID: PMC7685729.
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PubMed Mentions:
62 Fields:
Translation:
HumansCellsCTClinical Trials
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DDRE-10. IMMUNE PROFILES ASSOCIATE WITH OUTCOMES IN HLA-A*02:01+, H3.3K27M+ PATIENTS WITH DIFFUSE MIDLINE GLIOMAS TREATED WITH H3.3K27M PEPTIDE VACCINE COMBINED WITH POLY-ICLC: A PNOC REPORT. Neuro-Oncology. 2020 Nov 9; 22(Supplement_2):ii63-ii63.
Mueller MS, Taitt TJ, Villanueva-Meyer VJ, Bonner BE, Nejo NT, Lulla LR, Goldman GS, Banerjee BA, Chi CS, Whipple WN, Crawford CJ, Gauvain GK, Nazemi NK, Watchmaker WP, Almeida AN, Okada OK, Salazar SA, Gilbert GR, Nazarian NJ, Molinaro MA, Butterfield BL, Prados PM, Okada OH. .
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EPCO-10. CHANGES IN ALTERNATIVE SPLICING AND ASSOCIATED NEOANTIGENS DUE TO THERAPY. Neuro-Oncology. 2020 Nov 9; 22(Supplement_2):ii71-ii71.
Wang WL, Shamardani SK, Babikir BH, Catalan CF, Nejo NT, Chang CS, Philips PJ, Okada OH, Diaz DA. .
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The current state of immunotherapy for primary and secondary brain tumors: similarities and differences. Jpn J Clin Oncol. 2020 Oct 22; 50(11):1231-1245.
Nejo T, Mende A, Okada H. PMID: 32984905; PMCID: PMC7733526.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Neoantigen load and HLA-class I expression identify a subgroup of tumors with a T-cell-inflamed phenotype and favorable prognosis in homologous recombination-proficient high-grade serous ovarian carcinoma. J Immunother Cancer. 2020 05; 8(1).
Matsushita H, Hasegawa K, Oda K, Yamamoto S, Asada K, Karasaki T, Yabuno A, Nishijima A, Nejo T, Kobayashi Y, Sato S, Ikeda Y, Miyai M, Takahashi Y, Yamaguchi R, Fujiwara K, Aburatani H, Kakimi K. PMID: 32461346; PMCID: PMC7254153.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Increased Vascular Adhesion Protein 1 (VAP-1) Levels are Associated with Alternative M2 Macrophage Activation and Poor Prognosis for Human Gliomas. Diagnostics (Basel). 2020 Apr 27; 10(5).
Chang SJ, Tu HP, Lai YC, Luo CW, Nejo T, Tanaka S, Chai CY, Kwan AL. PMID: 32349342; PMCID: PMC7278017.
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PubMed Mentions:
14
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Tumor antigens in glioma. Semin Immunol. 2020 02; 47:101385.
Nejo T, Yamamichi A, Almeida ND, Goretsky YE, Okada H. PMID: 32037183.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimals
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COMP-02. MINING-GUIDED MACHINE LEARNING ANALYSES SUPPORTS GRASPING THE LATEST TRENDS ON NEURO-ONCOLOGY. Neuro-Oncology. 2019 Nov 11; 21(Supplement_6):vi61-vi61.
Hana HT, Tanaka TS, Nejo NT, Kitagawa KY, Takahashi TS, Koike KT, Kushihara KY, Yamazawa YE, Nomura NM, Takayanagi TS, Saito SN. .
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DDIS-02. DEVELOPMENT OF NOVEL SPRAY-TYPE FLUORESCENT PROBES FOR GLIOBLASTOMA DETECTION. Neuro-Oncology. 2019 Nov 11; 21(Supplement_6):vi65-vi65.
Kitagawa KY, Tanaka TS, Kuriki KY, Yamamoto YK, Nejo NT, Takahashi TS, Nomura NM, Hana HT, Koike KT, Kushihara KY, Yamazawa YE, Takayanagi TS, Mukasa MA, Kamiya KM, Urano UY, Saito SN. .
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PDCT-17 (LTBK-11). PNOC007: H3.3K27M SPECIFIC PEPTIDE VACCINE COMBINED WITH POLY-ICLC FOR THE TREATMENT OF NEWLY DIAGNOSED HLA-A2+ H3.3K27M MIDLINE GLIOMAS. Neuro-Oncology. 2019 Nov 11; 21(Supplement_6):vi284-vi285.
Mueller MS, Lulla LR, Goldman GS, Banerjee BA, Chi CS, Whipple WN, Crawford CJ, Gauvain GK, Nazemi NK, Nazarian NJ, Taitt TJ, Watchmaker WP, Nejo NT, Okada OK, Butterfield BL, Molinaro MA, Prados PM, Okada OH. .
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IMMU-30. UTILIZING A NOVEL MASS CYTOMETRY-BASED IMMUNOMONITORING PLATFORM FOR THE CHARACTERIZATION OF VACCINE-REACTIVE, EPITOPE-SPECIFIC CD8+ T-CELLS IN HLA-A*0201+ PATIENTS WITH K27M+ DIFFUSE MIDLINE GLIOMAS. Neuro-Oncology. 2019 Nov 11; 21(Supplement_6):vi125-vi125.
Taitt TJ, Watchmaker WP, Nejo NT, Almeida AN, Okada OK, Shahin SM, Gilbert GR, Mueller MS, Okada OH. .
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Spray Fluorescent Probes for Fluorescence-Guided Neurosurgery. Front Oncol. 2019; 9:727.
Kitagawa Y, Tanaka S, Kuriki Y, Yamamoto K, Ogasawara A, Nejo T, Matsuura R, Koike T, Hana T, Takahashi S, Nomura M, Takayanagi S, Mukasa A, Kamiya M, Urano Y, Saito N. PMID: 31448231; PMCID: PMC6691768.
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PubMed Mentions:
3
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Radiomics Analysis for Glioma Malignancy Evaluation Using Diffusion Kurtosis and Tensor Imaging. Int J Radiat Oncol Biol Phys. 2019 11 15; 105(4):784-791.
Takahashi S, Takahashi W, Tanaka S, Haga A, Nakamoto T, Suzuki Y, Mukasa A, Takayanagi S, Kitagawa Y, Hana T, Nejo T, Nomura M, Nakagawa K, Saito N. PMID: 31344432.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
Publisher Correction: DNA demethylation is associated with malignant progression of lower-grade gliomas. Sci Rep. 2019 May 23; 9(1):7935.
Nomura M, Saito K, Aihara K, Nagae G, Yamamoto S, Tatsuno K, Ueda H, Fukuda S, Umeda T, Tanaka S, Takayanagi S, Otani R, Nejo T, Hana T, Takahashi S, Kitagawa Y, Omata M, Higuchi F, Nakamura T, Muragaki Y, Narita Y, Nagane M, Nishikawa R, Ueki K, Saito N, Aburatani H, Mukasa A. PMID: 31118432; PMCID: PMC6531430.
View in:
PubMed Mentions:
1 Fields:
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Reduced Neoantigen Expression Revealed by Longitudinal Multiomics as a Possible Immune Evasion Mechanism in Glioma. Cancer Immunol Res. 2019 07; 7(7):1148-1161.
Nejo T, Matsushita H, Karasaki T, Nomura M, Saito K, Tanaka S, Takayanagi S, Hana T, Takahashi S, Kitagawa Y, Koike T, Kobayashi Y, Nagae G, Yamamoto S, Ueda H, Tatsuno K, Narita Y, Nagane M, Ueki K, Nishikawa R, Aburatani H, Mukasa A, Saito N, Kakimi K. PMID: 31088845.
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PubMed Mentions:
42 Fields:
Translation:
HumansCells
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???????·????????????????????????????. . 2019 Mar 1.
?? ??, Nejo NT. .
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DNA demethylation is associated with malignant progression of lower-grade gliomas. Sci Rep. 2019 02 13; 9(1):1903.
Nomura M, Saito K, Aihara K, Nagae G, Yamamoto S, Tatsuno K, Ueda H, Fukuda S, Umeda T, Tanaka S, Takayanagi S, Otani R, Nejo T, Hana T, Takahashi S, Kitagawa Y, Omata M, Higuchi F, Nakamura T, Muragaki Y, Narita Y, Nagane M, Nishikawa R, Ueki K, Saito N, Aburatani H, Mukasa A. PMID: 30760837; PMCID: PMC6374451.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Mining-Guided Machine Learning Analyses Revealed the Latest Trends in Neuro-Oncology. Cancers (Basel). 2019 Feb 03; 11(2).
Hana T, Tanaka S, Nejo T, Takahashi S, Kitagawa Y, Koike T, Nomura M, Takayanagi S, Saito N. PMID: 30717468; PMCID: PMC6406908.
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PubMed Mentions:
4
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Maffucci syndrome complicated by three different central nervous system tumors sharing an IDH1 R132C mutation: case report. J Neurosurg. 2019 12 01; 131(6):1829-1834.
Nejo T, Tanaka S, Ikemura M, Nomura M, Takayanagi S, Shin M, Ushiku T, Shibahara J, Saito N, Mukasa A. PMID: 30579273.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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IMMU-58. REDUCED NEOANTIGEN EXPRESSION AS A POSSIBLE IMMUNE EVASION MECHANISM DURING GLIOMA PROGRESSION. Neuro-Oncology. 2018 Nov 5; 20(suppl_6):vi134-vi134.
Nejo NT, Matushita MH, Karasaki KT, Nomura NM, Nagae NG, Takayanagi TS, Tanaka TS, Takahashi TS, Kitagawa KY, Hana HT, Koike KT, Narita NY, Nagane NM, Nishikawa NR, Ueki UK, Aburatani AH, Mukasa MA, Kakimi KK, Saito SN. .
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NIMG-55. RADIOMICS ANALYSIS FOR DETECTION OF IDH MUTATION OF GLIOMA USING DIFFUSION TENSOR AND KURTOSIS IMAGES. Neuro-Oncology. 2018 Nov 5; 20(suppl_6):vi188-vi188.
Takahashi TS, Takahashi TW, Tanaka TS, Haga HA, Nakamoto NT, Mukasa MA, Takayanagi TS, Suzuki SY, Koike KT, Kitagawa KY, Hana HT, Nejo NT, Nomura NM, Saito SN. .
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TMIC-42. DEVELOPMENT OF NOVEL SPRAY-TYPE FLUORESCENT PROBES FOR BRAIN TUMORS. Neuro-Oncology. 2018 Nov 5; 20(suppl_6):vi265-vi265.
Kitagawa KY, Tanaka TS, Ogasawara OA, Kuriki KY, Yamamoto YK, Koike KT, Hana HT, Takahashi TS, Nejo NT, Nomura NM, Takayanagi TS, Kamiya KM, Urano UY, Saito SN. .
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P04.14 Multiomics analysis on primary and recurrent paired tumors reveals a possible immune evasion mechanism through reduced neoantigen expression in some glioma. Neuro-Oncology. 2018 Sep 19; 20(suppl_3):iii281-iii281.
Nejo NT, Matsushita MH, Karasaki KT, Nomura NM, Takayanagi TS, Tanaka TS, Mukasa MA, Kakimi KK, Saito SN. .
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PATH-28. CLINICAL AND GENETIC CHARACTERISTICS OF DIFFUSE MIDLINE GLIOMA IN THE SPINAL CORD. Neuro-Oncology. 2017 Nov 6; 19(suppl_6):vi176-vi176.
Tanaka TS, Otani OR, Hongo HH, Matsuda MH, Ikemura IM, Nomura NM, Takayanagi TS, Nejo NT, Takahashi TS, Kitagawa KY, Hana HT, Mukasa MA, Ueki UK, Komori KT, Taniguchi TM, Saito SN, Kin KP. .
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GENE-10. CHARACTERISTIC MOLECULAR PROFILE CHANGES IN PRIMARY AND RECURRENT GLIOMAS DEPENDING ON THEIR HISTOPATHOLOGY. Neuro-Oncology. 2017 Nov 6; 19(suppl_6):vi94-vi94.
Mukasa MA, Nomura NM, Saito SK, Aihara AK, Nagae NG, Nejo NT, Tanaka TS, Takayanagi TS, Takahashi TS, Omata OM, Nakamura NT, Narita NY, Muragaki MY, Nagane NM, Ueki UK, Nishikawa NR, Aburatani AH, Saito SN. .
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RARE-02. PRIMARY SPINAL CORD EWING’S SARCOMA IN 50-YEAR-OLD WOMAN: A CASE REPORT. Neuro-Oncology. 2017 Nov 6; 19(suppl_6):vi212-vi212.
Takahashi TS, Takayanagi TS, Ikemura IM, Nejo NT, Nomura NM, Yanagisawa YS, Tanaka TS, Mukasa MA, Saito SN. .
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Distinct molecular profile of diffuse cerebellar gliomas. Acta Neuropathol. 2017 12; 134(6):941-956.
Nomura M, Mukasa A, Nagae G, Yamamoto S, Tatsuno K, Ueda H, Fukuda S, Umeda T, Suzuki T, Otani R, Kobayashi K, Maruyama T, Tanaka S, Takayanagi S, Nejo T, Takahashi S, Ichimura K, Nakamura T, Muragaki Y, Narita Y, Nagane M, Ueki K, Nishikawa R, Shibahara J, Aburatani H, Saito N. PMID: 28852847; PMCID: PMC5663812.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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Genetic and epigenetic stability of oligodendrogliomas at recurrence. Acta Neuropathol Commun. 2017 03 07; 5(1):18.
Aihara K, Mukasa A, Nagae G, Nomura M, Yamamoto S, Ueda H, Tatsuno K, Shibahara J, Takahashi M, Momose T, Tanaka S, Takayanagi S, Yanagisawa S, Nejo T, Takahashi S, Omata M, Otani R, Saito K, Narita Y, Nagane M, Nishikawa R, Ueki K, Aburatani H, Saito N. PMID: 28270234; PMCID: PMC5339990.
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PubMed Mentions:
29 Fields:
Translation:
HumansCells
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Limitations of Routine Verification of Nasogastric Tube Insertion Using X-Ray and Auscultation: Two Case Reports of Life-Threatening Complications. Nutr Clin Pract. 2016 Dec; 31(6):780-784.
Nejo T, Oya S, Tsukasa T, Yamaguchi N, Matsui T. PMID: 27207938.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Dorsal displacement of the facial nerve in acoustic neuroma surgery: clinical features and surgical outcomes of 21 consecutive dorsal pattern cases. Neurosurg Rev. 2016 Apr; 39(2):277-88; discussion 288.
Nejo T, Kohno M, Nagata O, Sora S, Sato H. PMID: 26621676.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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[An Endovascular Approach for Ruptured Aneurysms of the Basilar Trunk Perforating Artery]. No Shinkei Geka. 2015 Jul; 43(7):619-27.
Kanenaka N, Sato H, Abe H, Koike T, Nejo T, Fukui A, Torihashi K, Sora S, Kohno M. PMID: 26136326.
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Translation:
Humans
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Usefulness of repetitive intraoperative indocyanine green-based videoangiography to confirm complete obliteration of micro-arteriovenous malformations. Surg Neurol Int. 2015; 6:85.
Oya S, Nejo T, Fujisawa N, Tsuchiya T, Indo M, Nakamura T, Matsui T. PMID: 26015873; PMCID: PMC4443402.
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PubMed Mentions:
4
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Increased flow signal in compressed segments of the spinal cord in patients with cervical spondylotic myelopathy. Spine (Phila Pa 1976). 2014 Dec 15; 39(26):2136-42.
Chang HS, Nejo T, Yoshida S, Oya S, Matsui T. PMID: 25271503.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Pearls & Oy-sters: Anorexia and emaciation in patients with cerebellar hemangioblastoma. Neurology. 2014 Sep 30; 83(14):1298-300.
Oya S, Nejo T, Indo M, Matsui T. PMID: 25267985.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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A case of thalamic dementia due to DAVF. Nosotchu. 2013 Jan 1; 35(3):203.
Kanenaka KN, Sato SH, Abe AH, Nejo NT, Fukui FA, Teranishi TY, Torihashi TK, Miyakoshi MA, Sora SS, Kohno KM. .
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Effectiveness of coil embolization of cerebral aneurysms under high magnification using biplane flat panel detector. Journal of Neuroendovascular Therapy. 2013 Jan 1; 7(1):51.
KANENAKA KN, Hiroaki HS, Hajime HA, Takahide TN, FUKUI FA, TERANISHI TY, TORIHASHI TK, MIYAKOSHI MA, Shigeo SS, KOHNO KM. .
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