Tarjani Thaker, PhD

TitlePostdoctoral Scholar
InstitutionUniversity of California San Francisco
DepartmentCardiovascular Research Inst
Address555 Mission Bay Blvd South
San Francisco CA 94158
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    Collapse Biography 
    Collapse Awards and Honors
    NIH-NCI2017  - 2019Ruth L. Kirschstein National Research Service Award
    Program for Breakthrough Biomedical Research (PBBR) Posdoctoral Fellowship Program2015  - 2016PBBR Postdoctoral Independent Research Award
    NIH2014  - 2015NIH Institutional Research Service Award in Molecular and Cellular Basis of Cardiovascular Disease

    Collapse Research 
    Collapse Research Activities and Funding
    Deciphering Molecular Determinants of Activation in the HER2/HER3 Receptor Complex
    NIH/NCI F32CA216928Apr 1, 2017 - Mar 31, 2019
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Mishra R, Alanazi S, Yuan L, Solomon T, Thaker TM, Jura N, Garrett JT. Activating HER3 mutations in breast cancer. Oncotarget. 2018 Jun 12; 9(45):27773-27788. PMID: 29963236.
      View in: PubMed
    2. Liu L, Thaker TM, Freed DM, Frazier N, Malhotra K, Lemmon MA, Jura N. Regulation of Kinase Activity in the Caenorhabditis elegans EGF Receptor, LET-23. Structure. 2018 Feb 06; 26(2):270-281.e4. PMID: 29358026.
      View in: PubMed
    3. Chen Q, Vishnivetskiy SA, Zhuang T, Cho MK, Thaker TM, Sanders CR, Gurevich VV, Iverson TM. The rhodopsin-arrestin-1 interaction in bicelles. Methods Mol Biol. 2015; 1271:77-95. PMID: 25697518; PMCID: PMC4520306.
    4. Thaker TM, Sarwar M, Preininger AM, Hamm HE, Iverson TM. A transient interaction between the phosphate binding loop and switch I contributes to the allosteric network between receptor and nucleotide in Gai1. J Biol Chem. 2014 Apr 18; 289(16):11331-41. PMID: 24596087; PMCID: PMC4036270.
    5. Thaker TM, Tanabe M, Fowler ML, Preininger AM, Ingram-Smith C, Smith KS, Iverson TM. Crystal structures of acetate kinases from the eukaryotic pathogens Entamoeba histolytica and Cryptococcus neoformans. J Struct Biol. 2013 Feb; 181(2):185-9. PMID: 23159802; PMCID: PMC3565045.
    6. Thaker TM, Kaya AI, Preininger AM, Hamm HE, Iverson TM. Allosteric mechanisms of G protein-Coupled Receptor signaling: a structural perspective. Methods Mol Biol. 2012; 796:133-74. PMID: 22052489; PMCID: PMC3549666.
    7. Kaya AI, Thaker TM, Preininger AM, Iverson TM, Hamm HE. Coupling efficiency of rhodopsin and transducin in bicelles. Biochemistry. 2011 Apr 19; 50(15):3193-203. PMID: 21375271; PMCID: PMC3119548.
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