Theodore Miclau, MD

Title(s)Professor, Orthopaedic Surgery
SchoolSchool of Medicine
Address2540 23rd Street, #2908
San Francisco CA 94110
Phone628-206-8812
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    University of California, San Francisco, CA2019Diversity, Equity, and Inclusion Champion Training

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    Theodore Miclau III, MD is Professor and Vice Chairman of the Department of Orthopaedic Surgery at the University of California, San Francisco, and the Director of the University of California/San Francisco General Hospital Orthopaedic Trauma Institute. Dr. Miclau serves on many local and national committees, and editorial and grant-review panels. He is Past-President of the Orthopaedic Research Society (ORS), Orthopaedic Trauma Association (OTA), and Past-President of the International Combined Orthopaedic Research Societies. He is currently the Steering Committee Chair of the International Orthopaedic Trauma Association, Committee Chair of the Osteosynthesis and Trauma Care Foundation’s Research Committee, and Chair of the Clinical Science Advisory Committee for the AO Foundation. He organizes the Consortium of Orthopaedic Academic Traumatologists (COACT), which has the goal of enhancing the collaborative efforts of North American centers that engage in education and research in low and low-middle income countries, and the Asociación de Ciruganos Traumatólogos en las Americas (ACTUAR), which is a growing surgeon network dedicated to promoting research in Latin America. He is the course chair for the Annual San Francisco International Orthopaedic Trauma conference now in its 18th year and other conferences nationally and internationally. His research focuses on clinical studies of musculoskeletal injury care and basic research of bone repair and is supported by extramural grants from the US Department of Defense and the National Institutes of Health. He has published over 225 peer-reviewed research papers and 20 book chapters. He has teamed with a variety of organizations to develop research and clinical courses throughout the United States, Europe, and Latin America, and is an Honorary Member of multiple national orthopaedic societies, including the Federación Mexicana de Colegios De Ortopedia y Traumatologia (FEMECOT), Cuban Society of Orthopaedics and Traumatology (SCOT), Sociedad Colombiana de Cirugia Ortopedico y Traumatologia (SCCOT), and the Argentina Association of Orthopaedics and Traumatology (AAOT). He has recently been recognized with the Alfred R. Shands Award from the ORS, Transformative Contribution Award from the ICORS, and the Honorary Award from the Osteosynthesis and Trauma Care Foundation.
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    Understanding the Global Burden of Disease of Skeletal Fractures: the International Orthopaedic Multi-Center Study (INORMUS)
    NIH R01AR076654Sep 21, 2020 - Aug 31, 2022
    Role: Principal Investigator
    Mechanisms of Skeletal Stem Cell Dysfunctions in Traumatic Bone Injuries
    NIH R01AR072707Jul 12, 2018 - Apr 30, 2023
    Role: Principal Investigator
    A Murine Model of Polytrauma: Understanding the molecular basis of accelerated bone repair with concomitant traumatic brain injury
    NIH R21AR066847Mar 1, 2015 - Dec 31, 2017
    Role: Principal Investigator
    Functional roles of muscle in bone repair
    NIH R01AR057344Mar 1, 2010 - Jun 30, 2016
    Role: Principal Investigator
    Biology of stable and non-stable fracture repair
    NIH R01AR053645Feb 1, 2006 - Nov 30, 2011
    Role: Principal Investigator
    ROLE OF ANGIOGENESIS IN BONE REPAIR
    NIH K08AR002164Apr 4, 2000 - Mar 31, 2006
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Open fractures: Current treatment perspective. OTA Int. 2023 Jun; 6(3 Suppl):e240. Minehara H, Maruo A, Amadei R, Contini A, Braile A, Kelly M, Jenner L, Schemitsch GW, Schemitsch EH, Miclau T. PMID: 37533445; PMCID: PMC10392445.
      View in: PubMed   Mentions: 1  
    2. A Shifting Paradigm: Transformation of Cartilage to Bone during Bone Repair. J Dent Res. 2023 01; 102(1):13-20. Marcucio RS, Miclau T, Bahney CS. PMID: 36303415; PMCID: PMC9791286.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    3. Leadership development programs for healthcare professionals in low-and middle-income countries: A systematic review. Int J Health Plann Manage. 2022 Jul; 37(4):2149-2166. MacKechnie MC, Miclau TA, Cordero DM, Tahir P, Miclau T. PMID: 35398927.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Appendicular Fracture and Polytrauma Correlate with Outcome of Spinal Cord Injury: A Transforming Research and Clinical Knowledge in Spinal Cord Injury Study. J Neurotrauma. 2022 08; 39(15-16):1030-1038. Miclau TA, Torres-Espin A, Morshed S, Morioka K, Huie JR, El Naga AN, Chou A, Pascual L, Duong-Fernandez X, Kuo YH, Weinstein P, Dhall SS, Bresnahan JC, Beattie MS, Digiorgio A, Ferguson AR, Transforming Research and Clinical Knowledge in Spinal Cord Injury (TRACK-SCI) Investigators. PMID: 35255740; PMCID: PMC9536347.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Collagen X Longitudinal Fracture Biomarker Suggests Staged Fixation in Tibial Plateau Fractures Delays Rate of Endochondral Repair. J Orthop Trauma. 2022 Feb 01; 36(Suppl 2):S32-S39. Working ZM, Peterson D, Lawson M, O'Hara K, Coghlan R, Provencher MT, Friess DM, Johnstone B, Miclau T, Bahney CS. PMID: 35061649; PMCID: PMC10308601.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Smith-Petersen Versus Watson-Jones Approach Does Not Affect Quality of Open Reduction of Femoral Neck Fracture. J Orthop Trauma. 2021 Oct 01; 35(10):517-522. Patterson JT, Ishii K, Tornetta P, Leighton RK, Friess DM, Jones CB, Levine A, Maclean JJ, Miclau T, Mullis BH, Obremskey WT, Ostrum RF, Reid JS, Ruder JA, Saleh A, Schmidt AH, Teague DC, Tsismenakis A, Westberg JR, Morshed S. PMID: 34510125.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Cost Minimization Analysis of a Teledermatology Triage System in a Managed Care Setting. JAMA Dermatol. 2021 01 01; 157(1):52-58. Zakaria A, Miclau TA, Maurer T, Leslie KS, Amerson E. PMID: 33206146; PMCID: PMC7675221.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    8. Open Tibial Shaft Fractures: Treatment Patterns in Latin America. J Bone Joint Surg Am. 2020 Nov 18; 102(22):e126. Albright PD, MacKechnie MC, Roberts HJ, Shearer DW, Padilla Rojas LG, Segovia J, Quintero JE, Amadei R, Baldy Dos Reis F, Miclau T, and the ACTUAR Open Tibia Study Group. PMID: 32890042.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    9. Motivations and impact of international rotations in low- and middle-income countries for orthopaedic surgery residents: Are we on the same page? Am J Surg. 2021 02; 221(2):245-253. Roberts HJ, Albright PD, Shearer DW, Won N, MacKechnie MC, Richard Coughlin R, Miclau T, Morshed S, Sabharwal S, COACT Resident Rotation Study Group. PMID: 33092782.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. The Life of a Fracture: Biologic Progression, Healing Gone Awry, and Evaluation of Union. JBJS Rev. 2020 08; 8(8):e1900221. Hellwinkel JE, Miclau T, Provencher MT, Bahney CS, Working ZM. PMID: 32796195.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    11. A quantitative serum biomarker of circulating collagen X effectively correlates with endochondral fracture healing. J Orthop Res. 2021 01; 39(1):53-62. Working ZM, Morris ER, Chang JC, Coghlan RF, Johnstone B, Miclau T, Horton WA, Bahney CS. PMID: 32533783.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    12. Open Reduction Is Associated With Greater Hazard of Early Reoperation After Internal Fixation of Displaced Femoral Neck Fractures in Adults 18-65 Years. J Orthop Trauma. 2020 Jun; 34(6):294-301. Patterson JT, Ishii K, Tornetta P, Leighton RK, Friess DM, Jones CB, Levine A, Maclean JJ, Miclau T, Mullis BH, Obremskey WT, Ostrum RF, Reid JS, Ruder JA, Saleh A, Schmidt AH, Teague DC, Tsismenakis A, Westberg JR, Morshed S. PMID: 32079891.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    13. Optimizing Patient Function After Musculoskeletal Trauma: An Introduction. Injury. 2020 05; 51 Suppl 2:S1. Miclau T, Van Lieshout EMM. PMID: 32616295.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. The global burden of musculoskeletal injury in low and lower-middle income countries: A systematic literature review. OTA Int. 2020 Jun; 3(2):e062. Cordero DM, Miclau TA, Paul AV, Morshed S, Miclau T, Martin C, Shearer DW. PMID: 33937696; PMCID: PMC8022900.
      View in: PubMed   Mentions: 13  
    15. Knowledge deficits and barriers to performing soft-tissue coverage procedures: An analysis of participants in an orthopaedic surgical skills training course in Mexico. OTA Int. 2019 Dec; 2(4):e044. Albright PD, Mackechnie MC, Jackson JH, Chopra A, Holler JT, Flores Biard A, Padilla Rojas LG, Morshed S, Miclau T, Shearer DW, Terry MJ. PMID: 33937672; PMCID: PMC7997122.
      View in: PubMed   Mentions: 3  
    16. Differential fracture response to traumatic brain injury suggests dominance of neuroinflammatory response in polytrauma. Sci Rep. 2019 08 21; 9(1):12199. Morioka K, Marmor Y, Sacramento JA, Lin A, Shao T, Miclau KR, Clark DR, Beattie MS, Marcucio RS, Miclau T, Ferguson AR, Bresnahan JC, Bahney CS. PMID: 31434912; PMCID: PMC6704103.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    17. Minimally invasive plate osteosynthesis versus conventional open insertion techniques for osteosynthesis. Injury. 2018 Jun; 49 Suppl 1:S19-S23. Toogood P, Huang A, Siebuhr K, Miclau T. PMID: 29929686.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    18. Microenvironmental Regulation of Chondrocyte Plasticity in Endochondral Repair-A New Frontier for Developmental Engineering. Front Bioeng Biotechnol. 2018; 6:58. Wong SA, Rivera KO, Miclau T, Alsberg E, Marcucio RS, Bahney CS. PMID: 29868574; PMCID: PMC5962790.
      View in: PubMed   Mentions: 18  
    19. Fracture healing: A review of clinical, imaging and laboratory diagnostic options. Injury. 2017 Jun; 48 Suppl 1:S69-S75. Cunningham BP, Brazina S, Morshed S, Miclau T. PMID: 28483359.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    20. Barriers to Clinical Research in Latin America. Front Public Health. 2017; 5:57. Chomsky-Higgins K, Miclau TA, Mackechnie MC, Aguilar D, Avila JR, Dos Reis FB, Balmaseda R, Barquet A, Ceballos A, Contreras F, Escalante I, Elias N, Vincenti SI, Lozano C, Medina F, Merchan G, Segovia J, Guerado E, Quintero JE, Morshed S, Bhandari M, Miclau T. PMID: 28459047; PMCID: PMC5394164.
      View in: PubMed   Mentions: 7     Fields:    
    21. Stem Cell Therapies in Orthopaedic Trauma. J Orthop Trauma. 2015 Dec; 29 Suppl 12:S24-7. Marcucio RS, Nauth A, Giannoudis PV, Bahney C, Piuzzi NS, Muschler G, Miclau T. PMID: 26584262; PMCID: PMC4845034.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    22. The multifaceted role of the vasculature in endochondral fracture repair. Front Endocrinol (Lausanne). 2015; 6:4. Bahney CS, Hu DP, Miclau T, Marcucio RS. PMID: 25699016; PMCID: PMC4318416.
      View in: PubMed   Mentions: 57     Fields:    
    23. Status of road safety and injury burden: North America. J Orthop Trauma. 2014; 28 Suppl 1:S37-8. Shearer D, Morshed S, Miclau T. PMID: 24857996.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Modulation of macrophage activity during fracture repair has differential effects in young adult and elderly mice. J Orthop Trauma. 2014; 28 Suppl 1:S10-4. Slade Shantz JA, Yu YY, Andres W, Miclau T, Marcucio R. PMID: 24378434; PMCID: PMC3965608.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    25. Acute complications of patients with pelvic fractures after pelvic angiographic embolization. Clin Orthop Relat Res. 2013 Sep; 471(9):2906-11. Matityahu A, Marmor M, Elson JK, Lieber C, Rogalski G, Lin C, Belaye T, Miclau T, Kandemir U. PMID: 23846601; PMCID: PMC3734434.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    26. Beneficial effects of oxygen- and lactate-production in scaffold designs. Bone. 2013 Nov; 57(1):324. Marcucio R, Hunt TK, Miclau T. PMID: 23895996.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    27. Creating rigidly stabilized fractures for assessing intramembranous ossification, distraction osteogenesis, or healing of critical sized defects. J Vis Exp. 2012 Apr 11; (62). Yu YY, Bahney C, Hu D, Marcucio RS, Miclau T. PMID: 22525683; PMCID: PMC3466651.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    28. Use of osteobiologics in the management of osteoporotic fractures. J Orthop Trauma. 2011 Jun; 25 Suppl 2:S51-5. Nauth A, Miclau T, Bhandari M, Schemitsch EH. PMID: 21566475.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    29. Rejuvenation of the inflammatory system stimulates fracture repair in aged mice. J Orthop Res. 2010 Aug; 28(8):1000-6. Xing Z, Lu C, Hu D, Miclau T, Marcucio RS. PMID: 20108320; PMCID: PMC2892015.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    30. Action of IL-1beta during fracture healing. J Orthop Res. 2010 Jun; 28(6):778-84. Lange J, Sapozhnikova A, Lu C, Hu D, Li X, Miclau T, Marcucio RS. PMID: 20041490; PMCID: PMC2858256.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    31. Gene therapy for fracture healing. J Orthop Trauma. 2010 Mar; 24 Suppl 1:S17-24. Nauth A, Miclau T, Li R, Schemitsch EH. PMID: 20182229.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    32. Delayed internal fixation of femoral shaft fracture reduces mortality among patients with multisystem trauma. J Bone Joint Surg Am. 2009 Jan; 91(1):3-13. Morshed S, Miclau T, Bembom O, Cohen M, Knudson MM, Colford JM. PMID: 19122073; PMCID: PMC2663326.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    33. Variability in the assessment of fracture-healing in orthopaedic trauma studies. J Bone Joint Surg Am. 2008 Sep; 90(9):1862-8. Corrales LA, Morshed S, Bhandari M, Miclau T. PMID: 18762645; PMCID: PMC2663323.
      View in: PubMed   Mentions: 123     Fields:    Translation:Humans
    34. Qualitative and quantitative assessment of bone fragility and fracture healing using conventional radiography and advanced imaging technologies--focus on wrist fracture. J Orthop Trauma. 2008 Sep; 22(8 Suppl):S83-90. Firoozabadi R, Morshed S, Engelke K, Prevrhal S, Fierlinger A, Miclau T, Genant HK. PMID: 18753895.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    35. Outcome assessment in clinical trials of fracture-healing. J Bone Joint Surg Am. 2008 Feb; 90 Suppl 1:62-7. Morshed S, Corrales L, Genant H, Miclau T. PMID: 18292359.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    36. What's new in orthopaedic trauma. J Bone Joint Surg Am. 2007 Nov; 89(11):2560-77. Cole PA, Miclau T, Bhandari M. PMID: 17974910.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
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